Select your Country or Region

  • TargetMol | Compound LibraryArgentinaArgentina
  • TargetMol | Compound LibraryAustraliaAustralia
  • TargetMol | Compound LibraryAustriaAustria
  • TargetMol | Compound LibraryBelgiumBelgium
  • TargetMol | Compound LibraryBrazilBrazil
  • TargetMol | Compound LibraryBulgariaBulgaria
  • TargetMol | Compound LibraryCroatiaCroatia
  • TargetMol | Compound LibraryCyprusCyprus
  • TargetMol | Compound LibraryCzechCzech
  • TargetMol | Compound LibraryDenmarkDenmark
  • TargetMol | Compound LibraryEgyptEgypt
  • TargetMol | Compound LibraryEstoniaEstonia
  • TargetMol | Compound LibraryFinlandFinland
  • TargetMol | Compound LibraryFranceFrance
  • TargetMol | Compound LibraryGermanyGermany
  • TargetMol | Compound LibraryGreeceGreece
  • TargetMol | Compound LibraryHong KongHong Kong
  • TargetMol | Compound LibraryHungaryHungary
  • TargetMol | Compound LibraryIcelandIceland
  • TargetMol | Compound LibraryIndiaIndia
  • TargetMol | Compound LibraryIrelandIreland
  • TargetMol | Compound LibraryIsraelIsrael
  • TargetMol | Compound LibraryItalyItaly
  • TargetMol | Compound LibraryJapanJapan
  • TargetMol | Compound LibraryKoreaKorea
  • TargetMol | Compound LibraryLatviaLatvia
  • TargetMol | Compound LibraryLebanonLebanon
  • TargetMol | Compound LibraryMalaysiaMalaysia
  • TargetMol | Compound LibraryMaltaMalta
  • TargetMol | Compound LibraryMoroccoMorocco
  • TargetMol | Compound LibraryNetherlandsNetherlands
  • TargetMol | Compound LibraryNew ZealandNew Zealand
  • TargetMol | Compound LibraryNorwayNorway
  • TargetMol | Compound LibraryPolandPoland
  • TargetMol | Compound LibraryPortugalPortugal
  • TargetMol | Compound LibraryRomaniaRomania
  • TargetMol | Compound LibrarySingaporeSingapore
  • TargetMol | Compound LibrarySlovakiaSlovakia
  • TargetMol | Compound LibrarySloveniaSlovenia
  • TargetMol | Compound LibrarySpainSpain
  • TargetMol | Compound LibrarySwedenSweden
  • TargetMol | Compound LibrarySwitzerlandSwitzerland
  • TargetMol | Compound LibraryTaiwan,ChinaTaiwan,China
  • TargetMol | Compound LibraryThailandThailand
  • TargetMol | Compound LibraryTurkeyTurkey
  • TargetMol | Compound LibraryUnited KingdomUnited Kingdom
  • TargetMol | Compound LibraryUnited StatesUnited States
  • TargetMol | Compound LibraryOther CountriesOther Countries
Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

GluR

Glutamate receptors are synaptic and non synaptic receptors located primarily on the membranes of neuronal and glial cells.Glutamate receptors are responsible for the glutamate-mediated postsynaptic excitation of neural cells, and are important for neural communication, memory formation, learning, and regulation.

  • Dasolampanel
    T31208503294-13-1In house
    Dasolampanel (NGX-426) is an orally available ionotropic glutamate receptor AMPA and Kainate receptor antagonist for the study of chronic pain disorders, including neuropathic pain and migraine.
    • $762
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Hot
  • L-Glutamine
    T0326L56-85-9
    L-Glutamine (L-Glutamic acid 5-amide) , a non-essential amino acid, is synthesized from glutamic acid and ammonia.
    • $29
    In Stock
    Size
    QTY
    TargetMol | Citations Cited
  • Evans blue
    T0313314-13-6
    Evans blue (C.I. 23860) is an azo dye, inhibits L-glutamate uptake via the membrane-bound excitatory amino acid transporter (EAAT).
    • $41
    In Stock
    Size
    QTY
  • L-Glutamic acid monosodium salt
    T6871142-47-2
    L-Glutamic acid monosodium salt (MSG) (Monosodium glutamate) is an activator of mGlu1 receptor.
    • $33
    In Stock
    Size
    QTY
  • Kynurenic acid
    T65135492-27-3
    Kynurenic acid (Quinurenic acid) is an endogenous tryptophan active metabolite, a triple antagonist of NMDA, glutamate, α7 nicotinic acetylcholine receptor, and an agonist of GPR35/CXCR8 with neuroprotective and anticonvulsant properties. It has neuroprotective and anticonvulsant properties and can be used to study neurodegeneration and metabolism-related diseases.
    • $31
    In Stock
    Size
    QTY
  • CHPG hydrochloride
    T10809L In house
    CHPG hydrochloride is a selective agonist of mGluR5.
    • $85
    In Stock
    Size
    QTY
  • pep2-EVKI acetate(1315378-67-6 free base)
    TP1943L1
    Pep2-EVKI acetate is a cell-permeable peptide. Pep2-EVKI acetate interferes the interaction between protein interacting with C-kinase (PICK1) and GluR2 AMPA receptor subunits.
    • $166
    In Stock
    Size
    QTY
  • gamma-DGG acetate(6729-55-1 free base)
    T15369L2935387-13-4
    gamma-DGG acetate(6729-55-1 free base) (γ-D-Glutamylglycine) is a competitive blocker of AMPA receptor.
    • $48
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • VU 0285683
    T23509327056-22-4
    VU 0285683 is a specific negative allosteric modulator of mGluR5 with a high affinity for the MPEP binding site. VU 0285683 shows anxiolytic-like activity.
    • $58
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • (RS)-3-Hydroxyphenylglycine
    T2325931932-87-3
    PI-linked metabotropic glutamate receptors agonist
    • $30
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • LY382884
    T27949211566-75-5In house
    LY382884 is a selective and potent GluR5 kainate receptor antagonist with anxiolytic activity.LY382884 blocks blockade of mossy fibre LTP induction.
    • $748
    In Stock
    Size
    QTY
  • (S)-ATPO
    T3473252930-37-3
    (S)-ATPO is Competitive antagonist at GluR1-4 (AMPA-preferring) receptors.
    • $48
    In Stock
    Size
    QTY
  • DMeOB
    T2273640252-74-2
    DMeOB (3,3'-Dimethoxybenzaldazine) is a negative regulator with mGluR5 agonist activity and can be used to study neurological diseases.
    • $30
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • CBiPES hydrochloride
    T22638856702-40-4
    CBiPES hydrochloride (CBiPES HCl) is a potent orthosteric modulator of the mGlu2 receptor with an EC50 value of 92.8 nM.CBiPES hydrochloride blocks the action of WT and mGlu(3) receptors.CBiPES hydrochloride can be used to study neurological disorders like epilepsy and Parkinson's syndrome. CBiPES hydrochloride can be used to study neurological disorders like epilepsy and Parkinson's syndrome.
    • $173
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • LY339434 HCl
    T27947L In house
    LY339434 HCl is a low affinity GluR5 erythrocyte receptor agonist.LY339434 HCl causes rapid neuronal death primarily by affecting N-methyl-D-aspartate (NMDA) receptors.
    • $195
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • LY-2300559
    T27932889115-58-6In house
    LY-2300559 is an agonist of metabotropic glutamate receptor 2 (mGluR2) and can be used in studies about the treatment of migraine.
    • $350
    In Stock
    Size
    QTY
  • TC-N 22A
    T234401314140-00-5
    TC-N 22A is a strong, selective, oral active mGlu4 forward allosteric regulator (PAM) that can cross the blood-brain barrier. EC50 expression of TC-N 22A in BHK cells expressing human mGlu4 was 9 nM. TC-N 22A showed very low activity against mGlu 1, 2, 3, 5, and 7 receptors in excitation and forward allosteric models (EC50 >10 μM). TC-N 22A can be used in the study of central nervous system diseases.
    • $123
    In Stock
    Size
    QTY
  • 1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-
    T60224175340-21-3In house
    1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- is a low activity isomer of S 18986. S 18986 is a AMPA receptor positive modulator with EC2 (Concentration that doubles the intensity of the AMPA-induced current) of 35 μM.
    • $117
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • HexylHIBO
    T22840334887-43-3
    HexylHIBO is a type I mGluR antagonist that inhibits mGlu1a and mGlu5a, with Kb values of 140 and 110 μM, respectively.HexylHIBO decreases sEPSC in rats.
    • $77
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • S-Sulfo-L-cysteine sodium salt
    T233037381-67-1
    S-Sulfo-L-cysteine sodium salt shows a weak affinity for mGluR1α and mGluR5a at high concentrations and has potential antioxidant activity.
    • $109
    In Stock
    Size
    QTY
  • 3-MATIDA
    T3486518357-51-2In house
    3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 μM, rat mGluR-1a). Displays ≥ 40-fold selectivity over other receptors: mGluR-5, mGluR-2, mGluR-4 (mGluR-4a) (IC50 > 300 μM), NMDA and GluR (AMPA) (IC50 = 250 μM). 3-MATIDA act as a neuroprotectant in cultured murine cortical cells and rat hippocampal slice cultures in vitro.
    • $37
    In Stock
    Size
    QTY
  • KRP-199 sodium
    T27748L In house
    KRP-199 sodium sodium is highly potent and selective for AMPA-R in vitro and exhibits good neuroprotection in vivo.
    • $195
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • TAT-GluA2 3Y acetate(1404188-93-7 free base)
    TP2111L
    TAT-GluA2 3Y acetate is an inhibitor of AMPA receptor endocytosis.Systemic administration of Tat-GluA2(3Y) during the induction phase of d-amphetamine blocked maintenance of behavioural sensitization and attenuated the maintenance of neurochemical sensitization of rat.
    • $205
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • YM90K
    T8435154164-30-4
    YM90K (6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)-) hydrochloride is an antagonist of AMPA receptor.
    • $133
    In Stock
    Size
    QTY
  • NBQX Disodium
    T25853479347-86-9
    NBQX Disodium (FG9202 disodium) is a highly selective, competitive AMPA receptor antagonist with neuroprotective and anticonvulsant activity. NBQX Disodium is a salt of NBQX. NBQX is a potent and selective AMPA/rhodosinate receptor antagonist that can be used to antagonize the excitatory toxicity of glutamate. It has anticonvulsant effects in rodent models.
    • $62
    In Stock
    Size
    QTY
  • pep2-SVKI acetate
    TP1944L1
    Pep2-SVKI acetate(pep2-SVKI acetate (328944-75-8 free base)) is a synthetic peptide salt that prevents internalization of AMPA-type glutamate receptor.
    • $133
    In Stock
    Size
    QTY
  • (R)-3,4-DCPG HCl
    T23215L In house
    (R)-3,4-DCPG HCl is a potent and selective mGlu8a receptor agonist that activates metabotropic glutamate receptors on primary afferent terminals in the neonatal rat spinal cord.
    • $195
    In Stock
    Size
    QTY
  • (S)-3,4-DCPG HCl
    T23288L In house
    (S)-3,4-DCPG HCl ((S)-3,4-Dicarboxyphenylglycine HCl) is a selective metabotropic glutamate receptor 8a (mGluR8a) agonist that has an effect on human mGluR8-expressing AV12-664 cells with an EC50 of 31 nM.
    • $193
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • AZD 9272
    T14389327056-26-8In house
    AZD 9272 is a brain-permeable mGluR5 antagonist for the study of gastroesophageal reflux.
    • $42
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • (S)-3-Hydroxyphenylglycine
    T2329171301-82-1
    (S)-3-Hydroxyphenylglycine is an agonist of group I metabotropic glutamate receptors (mGluRs).
    • $128
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • AMPA receptor modulator-2
    T377342034181-36-5In house
    AMPA receptor modulator-2 (Example 134) is a AMPA receptor modulator, with a pIC50 of 10.1 for TARPγ2 dependent AMPA receptor[1]. pIC50 = -lgIC50. [1]. BERRY CYNTHIA G B (US), et al. AZABENZIMIDAZOLES AND THEIR USE AS AMPA RECEPTOR MODULATORS. Patent. WO2016176460.
    • $125
    In Stock
    Size
    QTY
  • VU6012962
    T133232313526-86-0In house
    VU6012962 is an orally bioavailable negative allosteric modulator of CNS-penetrant metabotropic glutamate receptor 7(mGlu7; IC50: 347 nM).
    • $31
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • Methoxy-PEPy
    T12012524924-76-3In house
    Methoxy-PEPy is a potent and selective mGlu5 receptor inhibitor with an IC50 value of 1 nM.
    • $30
    In Stock
    Size
    QTY
  • BMT-145027
    T105732018282-44-3In house
    BMT-145027 is a positive allosteric modulator of mGluR5 without inherent agonist activity (EC50 = 47 nM).
    • $38
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • Dipraglurant
    T15134872363-17-2In house
    Dipraglurant (ADX48621) is a negative alteration modulator (NAM) of mGluR5 that inhibits dyskinesia in the LID macaque model.
    • $98
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • S 18986
    T16816175340-20-2In house
    S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors, showcasing cognitive-enhancing properties in rodents. It induces the release of noradrenaline and acetylcholine in the rat hippocampus, leading to enhanced object-recognition memory.
    • $30
    In Stock
    Size
    QTY
  • IEM 1754 2HBr
    T6134162831-31-4In house
    IEM 1754 2HBr (IEM 1754 dihydrobromide) is a selective AMPA/kainate receptor blockers for GluR1 and GluR3 with IC50 of 6 μM.
    • $30
    In Stock
    Size
    QTY
  • CPPHA
    T10881693288-97-0In house
    CPPHA, a positive allosteric modulator of glutamate receptors mGluR5 and mGluR1, is commonly used in development for central nervous system diseases.
    • $33
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • 7-Chlorokynurenic acid
    T10191L18000-24-3In house
    7-Chlorokynurenic acid (7-chloro-4-hydroxy-2-carboxyquinoline) is an effecitve and selective antagonist of NMDA receptor with IC50 of 0.56 μM for the glycine B coagonist site. 7-Chlorokynurenic acid inhibits the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM and shows antinociceptive actions after neuraxial delivery.
    • $38
    In Stock
    Size
    QTY
  • CHPG sodium salt
    T108081303993-73-8In house
    CHPG sodium salt is a selective agonist of mGluR5 and activates the ERK and Akt signaling pathways. CHPG sodium salt can be used in studies about traumatic brain injury.
    • $40
    In Stock
    Size
    QTY
  • L-AP4
    T1569223052-81-5In house
    L-APB is an effective and specific agonist for the group III mGluRs (EC50s: 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6, and mGlu7 receptors, respectively).
    • $140
    35 days
    Size
    QTY
    TargetMol | Inhibitor Sale
  • Memantine hydrochloride
    T144341100-52-1
    Memantine hydrochloride (Memantine HCl) is an AMANTADINE derivative that has some dopaminergic effects. Memantine hydrochloride has been proposed as an antiparkinson agent.
    • $42
    In Stock
    Size
    QTY
    TargetMol | Citations Cited
  • CDPPB
    T22641781652-57-1
    CDPPB is a modulator of mGluR5 positive allosteric(with an EC50 of 27 nM in Chinese hamster ovary cells expressing human mGluR5).
    • $38
    In Stock
    Size
    QTY
    TargetMol | Citations Cited
  • NBQX
    T4113118876-58-7
    NBQX (FG9202) is a potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo.
    • $34
    In Stock
    Size
    QTY
    TargetMol | Citations Cited
  • Urethane
    T005151-79-6
    Urethane (Ethylurethane) was an antineoplastic agent .Now is used for other medicinal purposes.
    • $29
    In Stock
    Size
    QTY
    TargetMol | Citations Cited
  • Xanthurenic Acid
    T301059-00-7
    Xanthurenic Acid (8-Hydroxykynurenic acid), a molecule arising from tryptophan metabolism by transamination of 3-hydroxykynurenine, activates mGlu2/3 Metabotropic glutamate receptors (mGlu2 and mGlu3).
    • $30
    In Stock
    Size
    QTY
    TargetMol | Citations Cited
  • VU 0364439
    T61601246086-78-1
    VU 0364439 is a mGlu4 positive allosteric modulator (C50: 19.8 nM).
    • $40
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • VU0155041
    T35651093757-42-6
    VU0155041 is an effective and positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50: 798/693 nM, at human/rat).
    • $40
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • FTIDC
    T3483873551-53-2
    FTIDC is a highly potent and selective allosteric antagonist of mGluR1 receptors and shows very weak potency against human and rat mGluR5 receptors. The inhibition of FTIDC for mGluR1 receptors is shown to be in noncompetitive manner and displays IC50 val
    • $107
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • DL-AP3
    T2273020263-06-3
    DL-AP3 is a competitive group I metabotropic glutamate receptor antagonist and inhibitor of phosphoserine phosphatase.
    • $29
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale