GluR

Glutamate receptors are synaptic and non synaptic receptors located primarily on the membranes of neuronal and glial cells.Glutamate receptors are responsible for the glutamate-mediated postsynaptic excitation of neural cells, and are important for neural communication, memory formation, learning, and regulation.

Cat. No.	Product name	CAS No.	Purity
T23010	MNI 137	946619-21-2	98%
T23010	MNI 137 is a negative allosteric modulator of mGlu2. MNI 137 inhibits glutamate-induced calcium mobilization with IC50s of 8.3 and 12.6 nM for human and rat.
T15692	L-AP4	23052-81-5	98%
T15692	L-APB is an effective and specific agonist for the group III mGluRs (EC50s: 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6, and mGlu7 receptors, respectively).
T15369	Gamma-DGG	6729-55-1	98%
T15369	gamma-DGG is a competitive blocker of AMPA receptor.
T15819	LY377604	204592-94-9	98%
T15819	LY377604 is a human β3-adrenergic receptor agonist (EC50: 2.4 nM). It also a β1- and β2-adrenergic receptor antagonist.
T10808	CHPG sodium salt	1303993-73-8	98%
T10808	CHPG sodium salt is a selective agonist of mGluR5 and activates the ERK and Akt signaling pathways. CHPG sodium salt can be used in studies about traumatic brain...
T15618	JNJ-46281222	1254980-38-5	98%
T15618	JNJ-46281222 is an metabotropic glutamate (mGlu) 2-selective, highly potent PAM (positive allosteric modulator). It has nanomolar affinity (Kd = 1.7 nM) and a hi...
T6562	Latrepirdine dihydrochloride	97657-92-6	98%
T6562	Latrepirdine is an orally active, and neuroactive antagonist of multiple drug targets, including histamine receptors, GluR, and 5-HT receptors, used as an antihi...
T11906	LY 541850	852679-76-6	98%
T11906	LY541850 is a selective orthosteric mGlu2 agonist and mGlu3 antagonist with IC50 values of 0.161 μM and 0.038 μM, respectively.LY 541850 is claimed from human io...
T11311L	Foliglurax	1883329-51-8	98%
T11311L	Foliglurax is a highly selective brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) (EC50: 79 nM).
T11911	LY3020371 hydrochloride	1377615-44-5	98%
T11911	LY3020371 hydrochloride exerts an antidepressant-like signature in vivo. LY3020371 hydrochloride is a potent, selective metabotropic glutamate 2/3 receptor (mGlu...
T12520	Pomaglumetad methionil	956385-05-0	98%
T12520	Pomaglumetad methionil is an oral methionine prodrug of the potent specific agonist of mGlu2/3 receptor LY404039.
T4009	NS 1209	205645-02-9	98%
T4009	NS1209 is a AMPA receptor antagonist.
T35028	Valiglurax	1976050-09-5	98%
T35028	Valiglurax, also known as VU0652957 and VU2957, is a potent, selective, CNS penetrant, and orally bioavailable mGlu4 PAM. VU2957 possessed attractive in vitro an...
T15619	JNJ-46778212	1363281-27-9	98%
T15619	JNJ-46778212 is an effective mGlu5 allosteric modulator (EC50: 260 nM).
T15823	LYPLAL1-IN-1	1966129-74-7	98%
T15823	LYPLAL1-IN-1 is a selective covalent small-molecule inhibitor of Lysophospholipase-like 1 (IC50: 0.006 μM). LYPLAL1-IN-1 also enhances glucose production.
T15944	M77976	394237-61-7	98%
T15944	M77976 is the potential for the research of obesity and diabetes. M77976 is a specific ATP-competitive inhibitor of PDK4 (pyruvate dehydrogenase kinase isoforms ...
T12025	MFZ 10-7 hydrochloride	1779796-36-9	98%
T12025	MFZ 10-7 hydrochloride is a highly potent and selective negative allosteric modulator of mGluR5 NAM
T21935	AMN082	97075-46-2	98%
T21935	AMN 082 dihydrochloride is a selective metabotropic glutamate mGlu7 receptor agonist reported to exhibit antidepressant activity.
T14389	AZD 9272	327056-26-8	98%
T14389	AZD 9272 is a antagonist of brain penetrant mGluR5.
T13319	VU0652835	1848252-81-2	98%
T13319	VU0652835 is a negative allosteric modulator of metabotropic glutamate receptor subtype 5 (mGlu5) (IC50: 81 nM).