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LY-2300559

Name: LY-2300559
Brand: TargetMol
SKU: T27932
Price: 350 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T27932Cas No. 889115-58-6

Alias LY2300559

LY-2300559 is an agonist of metabotropic glutamate receptor 2 (mGluR2) and can be used in studies about the treatment of migraine.

LY-2300559

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Purity: 99.22%

Catalog No. T27932Alias LY2300559Cas No. 889115-58-6

LY-2300559 is an agonist of metabotropic glutamate receptor 2 (mGluR2) and can be used in studies about the treatment of migraine.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$350	In Stock	In Stock
5 mg	$828	In Stock	In Stock
10 mg	$1,130	In Stock	In Stock
25 mg	$1,590	In Stock	In Stock
50 mg	$1,980	In Stock	In Stock
100 mg	$2,500	In Stock	In Stock
500 mg	$4,900	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.22%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	LY-2300559 is an agonist of metabotropic glutamate receptor 2 (mGluR2) and can be used in studies about the treatment of migraine.
Synonyms	LY2300559

Chemical Properties

Molecular Weight	434.48
Formula	C₂₆H₂₆O₆
Cas No.	889115-58-6
Smiles	O(CC1=CC=C(C(O)C2=CC(C(O)=O)=CC=C2)C=C1)C3=C(CCC)C(O)=C(C(C)=O)C=C3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (138.1 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3016 mL	11.5080 mL	23.0160 mL	115.0801 mL
5 mM	0.4603 mL	2.3016 mL	4.6032 mL	23.0160 mL
10 mM	0.2302 mL	1.1508 mL	2.3016 mL	11.5080 mL
20 mM	0.1151 mL	0.5754 mL	1.1508 mL	5.7540 mL
50 mM	0.0460 mL	0.2302 mL	0.4603 mL	2.3016 mL
100 mM	0.0230 mL	0.1151 mL	0.2302 mL	1.1508 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc