tryptamine

Tryptamine is a monoamine alkaloid found in animals, plants, and fungi. It contains an indole ring structure and is structurally analogous to the tryptophan. It is found in trace amounts in the brains of mammals and is recognized to play a role as a neuro

CoA-S-trimethylene-acetyl-tryptamine (Coenzyme A-S-trimethylene-acetyl-tryptamine) is a derivative of coenzyme A.

PDAT is a noncompetitive Indolethylamine N-methyltransferase inhibitor.

Heterocyclic compound-indole, intermediate and building block

Tryptamine hydrochloride is a monoamine alkaloid, metabolite of tryptophan and CNS active substance, agonist of 5-HT4 receptor, TAAR1 and AHR, with potential for blood-brain barrier permeability.

Tryptamine (Standard) is the standard substance of Tryptamine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Tryptamine is a monoamine alkaloid found in animals, plants, and fungi. It contains an indole ring structure and is structurally analogous to the tryptophan. It is found in trace amounts in the brains of mammals and is recognized to play a role as a neurotransmitter or neuromodulator.

N-Acetyl-5-hydroxytryptamine (O-Demethylmelatonin) , also known as Normelatonin, is the immediate precursor of melatonin. It is produced from serotonin by the enzyme aralkylamine N-acetyltransferase and is converted to melatonin by acetylserotonin O-methyltransferase. It can potently activate TrkB receptor.

5-Methyltryptamine hydrochloride is a high-affinity 5-HT1C receptor ligand and a partial agonist of 5-HT. 5-Methyltryptamine hydrochloride protects mice subjected to burn, tourniquet and endotoxin shock.

6-Fluorotryptamine hydrochloride is a compound used as a molecular structural unit and is a derivative of the natural tryptamine alkaloid serotonin. It is an agonist at 5-HT2A and 5-HT2C serotonin receptors, making it a potential candidate for the development of new drugs for the treatment of various psychiatric and neurological disorders.

5-Methoxy-alpha-ethyltryptamine is a psychoactive substance that can cause various effects. It belongs to the tryptamine chemical class and can be used for various psychoactive and stimulant effects.

4-Hydroxytryptamine creatinine sulfate, a derivative of tryptamine, acts as an agonist for neurotransmitters.

N-Salicyloyltryptamine(STP) is a tryptamine analogue with anticonvulsant, anti-inflammatory, analgesic, and vasorelaxation effect. N-Salicyloyltryptamine acts as the voltage-dependent Na +, Ca 2+, and K + ion channels inhibitor which inhibits K + currents with an IC 50 value of 34.6 μM ( /to) [1] - [5].

5-Bromo-N,N-dimethyltryptamine is an active metabolite and a potential candidate for antidepressant and sedative medications. It has affinity for the serotonin receptor subtypes 5-HT1A, 5-HT2B, 5-HT6, and 5-HT7.

Ethylpropyltryptamine (EPT) is an orally active novel psychoactive substance. It is predicted to act as a partial agonist of the 5-HT2A receptor.

6-Fluoro-N,N-diethyltryptamine (6-F-DET) exhibits affinity for the 5-HT2A receptor.

5-Fluoro-α-methyltryptamine hydrochloride may increase intracellular 5-HT levels, subsequently enhancing the release of 5-HT. The EC50 values for 5-Fluoro-α-methyltryptamine hydrochloride are 37 nM for dopamine (DA), 14 nM for 5-hydroxytryptamine (5-HT), 78 nM for norepinephrine (NE), and 8.47 nM for the 5-HT2A receptor.

5-Chloro-α-methyltryptamine (Compound 7b) is a potent and selective dual DA/5-HT releaser and 5-HT2a agonist. Its EC50 values for the release of DA and 5-HT are 54.3 nM and 16.2 nM, respectively. This compound can be used in neurotransmitter research.

2-Methyl-N,N-dimethyltryptamine (2,N,N-TMT, compound 15) exhibits binding affinity for the serotonin (5-HT) receptor, with a pA2 value of 6.04. It plays a significant role in neurological disease research.

5-Benzyloxytryptamine (5-BT) is a selective partial agonist of the 5-hydroxytryptamine 1D/1B (5-HT1D/1B) receptors, with an IC50 value of 40 nM for the bovine caudate nucleus 5-HT1D. It exhibits much lower affinity for other receptors (5-HT2 IC50 > 470 nM). 5-Benzyloxytryptamine inhibits adenylate cyclase, leading to reduced neurotransmitter release and downregulation of cAMP signaling. It holds potential for research into diseases associated with neurotransmitter imbalances.

5-Carboxamidotryptamine maleate (5-CT maleate) is a receptor agonist with antihypertensive and glucose-raising effects.

5-HT1B agonist

5-HT2B receptor agonist

5-Hydroxytryptamine creatinine sulfate monohydrate (Serotonin creatinine sulfate monohydrate) is a neurotransmitter.

7-FluorotryptaMine HCl is a potent aromatic monoamine GPRC5A agonist that induces GPRC5A-mediated β-arrestin recruitment.7-FluorotryptaMine HCl can be used to study signalling pathways related to immunity and cancer.