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Search Result

Search Results for "serotonin receptor"

Libraries

Serotonin Receptor-Targeted Compound Library
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Compounds

Cat No. Product Name
T8441 Lerisetron 5-HT Receptor
Lerisetron 是5-HT3拮抗剂，与 5-HT3受体具有高亲和力(pKi:9.2)。它对尿烷麻醉大鼠的 5-HT 引发的反射性心率过缓具有抑制作用。
T2209 Serotonin hydrochloride 5-羟基色胺盐酸盐,5-HT HCl,5-Hydroxytryptamine hydrochloride,5-HT hydrochloride,Serotonin HCl Transferase , 5-HT Receptor , Endogenous Metabolite
Serotonin hydrochloride 是一种内源性 5-HT 受体激动剂、CNS 中的单胺神经递质和儿茶酚 O-甲基转移酶 (COMT) 抑制剂，Ki 值为 44 μM。
T0031L2 Ziprasidone 齐拉西酮,CP-88059,Zeldox,Geodon Norepinephrine , 5-HT Receptor , Dopamine Receptor , Histamine Receptor , Adrenergic Receptor
Ziprasidone 是一种联合的 5-HT（5-羟色胺）和多巴胺受体拮抗剂，具有强大的抗精神病活性。它是去甲肾上腺素再摄取抑制剂，对大鼠和人的5-HT1A，5-HT2A 和多巴胺 D2 受体有很高的亲和力。
T1566 Aripiprazole OPC-14597,阿立哌唑 5-HT Receptor
Aripiprazole 是血清素受体 5-HT1A 和多巴胺 D2 受体的部分激动剂，还用作突触后拮抗剂和血清素受体 5-HT2A 的拮抗剂。
T3648 Hypidone hydrochloride YL0919 5-HT Receptor
YL0919 是一种新型抗抑郁候选药物，具有作为 5-HT1A 受体激动剂和选择性 5-羟色胺再摄取抑制剂的双重活性。
T12172 NAN-190 hydrobromide 5-HT Receptor
NAN-190 hydrobromide 是一种5-HT1A 选择性拮抗剂。
T4568 Dolasetron MDL-73147,多拉司琼 5-HT Receptor
Dolasetron 是一种血清素 5-HT3 受体拮抗剂，用于治疗化疗后的恶心和呕吐。
T1279 Vilazodone 维拉佐酮,SB659746A,EMD 68843 5-HT Receptor , Serotonin Transporter
Vilazodone 是一种可口服的选择性 5 -羟色胺再摄取抑制剂 (SSRI) 和部分5-HT1A 受体激动剂。它有抗抑郁作用，可用于抑郁症和情绪性疾病的研究。
T1042 Granisetron hydrochloride BRL 43694A,Granisetron HCl,盐酸格拉司琼 5-HT Receptor
Granisetron hydrochloride 是一种5-HT3受体拮抗剂，可作为化疗后止吐剂。
T1735 Lurasidone hydrochloride 盐酸鲁拉西酮,SM-13496 (Hydrochloride),SM-13496,Lurasidone HCl Norepinephrine , 5-HT Receptor , Dopamine Receptor
Lurasidone hydrochloride 是多巴胺 D2和5-HT7的拮抗剂，IC50值分别为 1.68 和 0.495 nM，用于治疗精神分裂症和双相情感障碍。它也是5-HT1A 受体的部分激动剂，IC50值为 6.75 nM。
T4562L Ramosetron hydrochloride 盐酸雷莫司琼,YM 060,YM-060,YM060 5-HT Receptor
Ramosetron Hydrochloride 是一种 5-HT3 受体拮抗剂，用于治疗以腹泻为主的肠易激综合征和恶心。
T5389 Volinanserin 氟利色林,M 100907,MDL100907 5-HT Receptor
Volinanserin 是选择性的5-HT2受体拮抗剂，Ki 值为 0.36 nM，可用于精神疾病的研究。它对 5-HT2 受体的选择性比 5-HT1c、α-1 肾上腺素能受体和 σ 受体高 300 倍。
T0031 Ziprasidone hydrochloride monohydrate CP 88059,齐拉西酮盐酸盐一水合物,盐酸齐拉西酮水合物 Adrenergic Receptor , Norepinephrine , Dopamine Receptor , Histamine Receptor , 5-HT Receptor
Ziprasidone hydrochloride monohydrate 是一种联合 5-HT（5-羟色胺）和多巴胺受体拮抗剂，具有抗精神病活性的强效作用。它也是去甲肾上腺素再摄取抑制剂。
T2589 Dolasetron Mesylate hydrate 多拉司琼甲磺酸盐一水合物,Dalasetron Mesylate Hydrate 5-HT Receptor
Dolasetron Mesylate hydrate 是一种选择性血清素受体拮抗剂，可竞争性阻断血清素对 5HT3 受体的作用，从而抑制化疗和放疗引起的恶心和呕吐。
T39161 Ro60-0175 Ro60-0175 5-HT Receptor
Ro60-0175 是 5- 羟色胺 2B (5-HT2B) 和 5- 羟色胺 2C (5-HT2C) 血清素受体亚型的选择性激动剂，常用富马酸盐形式。 它具有 5- 羟色胺 2B 受体激动剂和 5- 羟色胺 2C 受体激动剂的作用。
TN1032 Geissoschizine methyl ether 缝籽木嗪甲醚,缝籽嗪甲醚 5-HT Receptor
Geissoschizine methyl ether 是从钩藤中发现的一种生物碱，是 Yokukansan 的主要活性成分，具有精神药物作用。它是一种有效的 5-羟色胺 A 受体激动剂，是 Yokukansan 改善攻击性和社交性的候选药...
T3431 Pardoprunox hydrochloride SLV-308 hydrochloride,DU-126891 hydrochloride,帕多芦诺盐酸盐 Dopamine Receptor , Adrenergic Receptor , 5-HT Receptor
Pardoprunox hydrochloride 是多巴胺受体 D2、D3部分激动剂和5-HT1A 激动剂，pEC50分别为 8、9.2 和 6.3。
T1066 Ketanserin R41468,Ketanserin tartrate,Ketanserinum,酮色林,凯他色林 5-HT Receptor , Autophagy , Potassium Channel
Ketanserin 是一种喹唑啉衍生物和 5-羟色胺受体亚型 2 拮抗剂，具有潜在的抗高血压和抗血小板活性。它也浓度依赖性抑制 hERG 电流，IC50为 0.11 μM。
T0162 Quetiapine Quetiapin,ICI204636,喹硫平 Dopamine Receptor , Adrenergic Receptor , 5-HT Receptor , AChR , Histamine Receptor
Quetiapine 是5-HT 受体激动剂和多巴胺受体拮抗剂，对人5-HT1A 的 pEC50值为 4.77，对人 D2的 pIC50值为 6.33。它用于治疗精神分裂症，以及治疗与 I 型双相情感障碍相关的急性躁狂发作。它对人 D2、H...
T1173 Tropisetron hydrochloride SDZ-ICS 930,ICS 205-930,Tropisetron HCl,盐酸托烷司琼 5-HT Receptor
Tropisetron Hydrochloride 是5-HT3受体拮抗剂和α7-烟碱受体激动剂，具有抗恶心和止吐活性，对5-HT3受体的 IC50为70.1 nM。
Lerisetron
T8441
synonym:
Target:
Serotonin hydrochloride
T2209
synonym: 5-羟基色胺盐酸盐,5-HT HCl,5-Hydroxytryptamine hydrochloride,5-HT hydrochloride,Serotonin HCl
Target:
Ziprasidone
T0031L2
synonym: 齐拉西酮,CP-88059,Zeldox,Geodon
Target:
Aripiprazole
T1566
synonym: OPC-14597,阿立哌唑
Target:
Hypidone hydrochloride
T3648
synonym: YL0919
Target:
NAN-190 hydrobromide
T12172
synonym:
Target:
Dolasetron
T4568
synonym: MDL-73147,多拉司琼
Target:
Vilazodone
T1279
synonym: 维拉佐酮,SB659746A,EMD 68843
Target:
Granisetron hydrochloride
T1042
synonym: BRL 43694A,Granisetron HCl,盐酸格拉司琼
Target:
Lurasidone hydrochloride
T1735
synonym: 盐酸鲁拉西酮,SM-13496 (Hydrochloride),SM-13496,Lurasidone HCl
Target:
Ramosetron hydrochloride
T4562L
synonym: 盐酸雷莫司琼,YM 060,YM-060,YM060
Target:
Volinanserin
T5389
synonym: 氟利色林,M 100907,MDL100907
Target:
Ziprasidone hydrochloride monohydrate
T0031
synonym: CP 88059,齐拉西酮盐酸盐一水合物,盐酸齐拉西酮水合物
Target:
Dolasetron Mesylate hydrate
T2589
synonym: 多拉司琼甲磺酸盐一水合物,Dalasetron Mesylate Hydrate
Target:
Ro60-0175
T39161
synonym: Ro60-0175
Target:
Geissoschizine methyl ether
TN1032
synonym: 缝籽木嗪甲醚,缝籽嗪甲醚
Target:
Pardoprunox hydrochloride
T3431
synonym: SLV-308 hydrochloride,DU-126891 hydrochloride,帕多芦诺盐酸盐
Target:
Ketanserin
T1066
synonym: R41468,Ketanserin tartrate,Ketanserinum,酮色林,凯他色林
Target:
Quetiapine
T0162
synonym: Quetiapin,ICI204636,喹硫平
Target:
Tropisetron hydrochloride
T1173
synonym: SDZ-ICS 930,ICS 205-930,Tropisetron HCl,盐酸托烷司琼
Target:
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