d-9

TrxR-IN-D9 is a novel inhibitor of thioredoxin reductase (TrxR).

NITD-916 is an orally active and highly lipophilic inhibitor of Mycobacterium enoyl reductase InhA with an IC50 of 570 nM.NITD-916 is a potent 4-hydroxy-2-pyridone derivative that forms a ternary complex with InhA and NADH, preventing access to the fatty acyl substrate-binding pocket.NITD-916 exhibits antituberculosis activity.

2-Aminopurine-9-beta-D-(2'-deoxy)riboside, a derivative of 2-Aminopurine, is a modified nucleoside composed of a purine base linked to a (2'-deoxy)ribose sugar moiety.

[D-Trp8]-γ-MSH acetate(321351-81-9 free base) is a selective melanocortin 3 (MC3) receptor agonist (IC50 values are 6.7, 340 and 600 nM for human MC3, MC5 and MC4 receptors respectively) and displays anti-inflammatory efficacy.

CRBN ligand-9 (2-(2,6-dioxopiperidin-3-yl)-5-nitroisoindoline-1,3-dione) exhibit inhibition of CRBN.

N6-Benzoyl-9-β-D-arabinofuranosyladenine hydrate is the hydrated form of N6-Benzoyl-9-β-D-arabinofuranosyladenine, which is an adenine nucleoside analog. Such adenosine analogs often function as vasodilators for smooth muscle and have been shown to inhibit cancer progression. Popular related products include Adenosine phosphate, Acadesine, Clofarabine, Fludarabine phosphate, and Vidarabine.

2,6-Dichloropurine-9-β-D-riboside is a building block.1,2It has been used in the synthesis of photoaffinity probes for nucleotide binding sites in proteins. 1.Wower, J., Hixson, S.S., Sylvers, L.A., et al.Synthesis of 2,6-diazido-9-(β-D-ribofuranosyl)purine 3',5'-bisphosphate: Incorporation into transfer RNA and photochemical labeling of Escherichia coli ribosomesBioconjug. Chem.5(2)158-161(1994) 2.Seiter, M.S., Bauer, M.P., Bogel, P.D., et al.Synthesis of novel spin-labeled photoaffinity derivatives of NAD+ and ATP and their characterization as coenzymes and substrates of several enzymesSynthesis2269-273(1996)

(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-6-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanoic acid is a useful organic compound for research related to life sciences. The catalog number is T65199 and the CAS number is 146987-10-2.

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2,4-difluoro-D-phenylalanine is a valuable organic compound for life sciences research. Its catalog number is T66882 and its CAS number is 1217820-78-4.

7-Cyclopropyl methyl-7,8-dihydro-8-oxo-9-(β-D-ribofuranosyl)guanine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis , etc [1] .

6-Methoxypurine-9-beta-D-(3-methoxy riboside), a purine nucleoside analog, exhibits extensive antitumor effects, particularly against indolent lymphoid malignancies. Its anticancer mechanisms include the inhibition of DNA synthesis and the induction of apoptosis, among others [1].

6-Methoxy-9-beta-D-(2-C-ethynyl-ribofuranosyl) purine is a purine nucleoside analog with broad antitumor activity targeting indolent lymphoid malignancies. Its anticancer mechanisms include inhibition of DNA synthesis and induction of apoptosis [1].

6-Methoxypurine-9-β-D-5'(R)-C-methylriboside, an analog of hypoxanthine—a purine base predominantly found in muscle tissue and a metabolite generated when purine oxidase acts on xanthine—displays anti-inflammatory properties and functions as a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. Its cytoprotective role is underscored by its ability to inhibit PARP activity, thus preventing peroxynitrite-induced mitochondrial depolarization and subsequent superoxide production. Furthermore, hypoxanthine serves as a biomarker for hypoxia [1] [2].

9-(5(R)-C-Methyl-2,3,5-tri-O-benzoyl-D-ribofuranosyl)-6-chloropurine, a purine nucleoside analog, demonstrates broad antitumor activity, particularly against indolent lymphoid malignancies, through inhibition of DNA synthesis and induction of apoptosis. [1]

[D-Leu6, Val7]-LH-RH (1-9) Ethyl Amide is an LH-RH peptide analogue.

Dihydrodehydrodiconiferyl alcohol 9-O-β-D-xylopyranoside serves as an anti-hepatitis B virus (anti-HBV) agent, effectively inhibiting the secretion of HBV surface antigen (HBsAg) and HBV e antigen (HBeAg) in the Hep G2.2.15 cell line, with IC50 values of 1.67 mM for HBsAg and over 2.15 mM for HBeAg [1].

ent-9-Hydroxy-15-oxo-16-kauren-19-oic acid beta-D-glucopyranosyl ester is a natural product for research related to life sciences. The catalog number is TN3955 and the CAS number is 81263-96-9.

(7R,8R)-Dihydrodehydrodiconiferyl alcohol 9-O-β-D-glucoside is a natural product for research related to life sciences. The catalog number is TN5432 and the CAS number is 351346-10-6.

Toralactone-9-O-β-D-glucopyranoside is a phenolic compound that can be extracted from Eriocaulon buergerianum.

9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(thiophen-3-yl)purine is a Nucleoside Derivative - Fluoro-modified nucleoside, 6-Modified purine nucleoside, 3'-Modified nucleoside.

9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-phenylpurine is a fluoro-modified nucleoside derivative, specifically a 6-modified purine nucleoside and a 3'-modified nucleoside.

9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(pyridine-4-yl)purine is a nucleoside derivative, specifically a fluoro-modified nucleoside, 6-modified purine nucleoside, and 3'-modified nucleoside.

9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(naphthalen-1-yl)purine is a nucleoside derivative characterized as a fluoro-modified, 6-modified purine, and 3'-modified nucleoside.

9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(5-phenylpyridin-3-yl)purine is a nucleoside derivative: fluoro-modified nucleoside, 6-modified purine nucleoside, 3'-modified nucleoside.