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Anti-human CD71 Antibody (5D995)

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Catalog No. TMAB-07418 Copy Product Info
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Anti-human CD71 Antibody (5D995) is a Mouse antibody targeting human CD71. Anti-human CD71 Antibody (5D995) can be used in ICC/IF,FCM.
Anti-human CD71 Antibody (5D995)
Pack SizePriceUSA StockGlobal StockQuantity
100 μg$3557-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-human CD71 Antibody (5D995) is a Mouse antibody targeting human CD71. Anti-human CD71 Antibody (5D995) can be used in ICC/IF,FCM.
Ig Type
Mouse IgG1, k
Clone
5D995
Reactivity
Human
Application
Recommended Dose
ICC/IF: 1:100-500; FCM: 1μg/Test
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationCell membrane; Single-pass type II membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
ConstructionHybridoma Monoclonal Antibody
PurificationProtein G purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4).
Concentration1mg/ml
Research BackgroundThis gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Transferrin receptor
Antigen Species
Human
Gene Name
TFRC
Gene ID
Protein Name
Transferrin receptor protein 1
Uniprot ID
Function
Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferring for an overlapping C-terminal binding site.
Chemical Properties
Molecular WeightTheoretical: 74/85 kDa. Actual: 95 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Related Tags: Anti-human CD71 Antibody (5D995) chemical structure | Anti-human CD71 Antibody (5D995) molecular weight