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Search Result

Search Results for " smo "

Targets

Hedgehog/Smoothened Smo Hedgehog/Smoothened

67

Compounds

27

Natural Products

26

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T63429 SMO-IN-2 Hedgehog/Smoothened
SMO-IN-2 is a potent smoothened (SMO) inhibitor of hedgehog (Hh) signaling.SMO-IN-2 shows antiproliferative activity and anticancer activity against human medulloblastoma cell lines.SMO-IN-2 can be used in the study of c...
T63387 SMO-IN-3
SMO-IN-3 is a potent inhibitor of smoothened (SMO) that acts on the hedgehog (Hh) signaling pathway (IC50: 34.09 nM). SMO-IN-3 inhibits the proliferation of Daoy, a human medulloblastoma cell line, and exhibits anticance...
T61897 SMO-IN-1
SMO-IN-1 (Compound 15) is an oral effective Smoothened (SMO) inhibitor. The EC50 value of sonic Hh protein (shh) is 89 nM.
T3460 HhAntag Hedgehog/Smoothened , Smo
HhAntag is a small molecule inhibitor of GLI1-mediated transcription, an essential down-stream element of the Hedgehog (Hh) pathway with the anti-tumor activity.
T23027 MRT-10 Hedgehog/Smoothened
MRT-10 is a Smoothened (Smo) receptor antagonist.
T14188 ALLO-2 Hedgehog/Smoothened , Smo
ALLO-2 is a Inhibitor of Drug-Resistant Smo Mutant.It inhibits Smo agonist Hh-Ag1.5-induced luciferase expression in TM3-Gli-Luc cells with IC50 of 6 nM.
T12109 MRT-83 Smo
MRT-83 is a potent Smo antagonist.
T2450 SANT-1 SANT 1 Hedgehog/Smoothened , Smo
SANT-1 directly binds to Smoothened (Smo) receptor (Kd: 1.2 nM) and inhibits Smo agonist effects (IC50: 20 nM).
T9531 MRT-14 Smo
MRT-14 is a potent Smo antagonist and can be used in several types of cancers linked to abnormal Hh signaling studies.
T6891 MK-4101 Apoptosis , Hedgehog/Smoothened , Smo
MK-4101, an effective inhibitor of the Hedgehog pathway, has anti-tumor activity through the induction of extensive apoptosis and inhibition of proliferation in tumor cells.
T2666 Taladegib LY2940680 Hedgehog/Smoothened , Smo
Taladegib (LY2940680) is an orally bioavailable small molecule antagonist of the Hedgehog (Hh)-ligand cell surface receptor smoothened (Smo) with potential antineoplastic activity.
T6514 Glasdegib PF-04449913 Hedgehog/Smoothened , Smo
Glasdegib (PF-04449913) (PF-04449913) is a potent, and orally bioavailable Smoothened (Smo) inhibitor with IC50 of 5 nM. Phase 2.
T1810 Purmorphamine Shh Signaling Antagonist VI Hedgehog/Smoothened , Smo , Autophagy
Purmorphamine (Shh Signaling Antagonist VI), which directly binds and activates Smoothened, blocks BODIPY-cyclopamine binding to Smo. It also is an inducer of osteoblast differentiation.
T24159 IHR-1 IHR 1 Smo
IHR-1 is a Potent Smo antagonist (IC50 = 7.6 nM). Selectively inhibits Hedgehog signaling over Wnt and Notch signaling pathways. Blocks Smo accumulation in primary cilium in vitro.
T1779 SAG Smoothened Agonist (SAG) HCl,Smoothened Agonist Hedgehog/Smoothened , Smo
SAG (Smoothened Agonist) is a Smo receptor agonist (EC50=3 nM) that is cell-permeable and selective. SAG regulates Smo activity by binding directly to the Smo helix and can activate the Hedgehog signaling pathway.
T11838 LEQ506 NVP-LEQ506 Smo
LEQ506 is a Smo inhibitor with IC50s of 2 nM and 4 nM for hSmo and mSmo, respectively.
T22814 GSA-10 Hedgehog/Smoothened
Smoothened (Smo) receptor agonist
T5465 PF-5274857 PF-5274857 freebase Smo
PF-5274857 (PF-5274857 free base) is an effective and selective hedgehog signaling pathway inhibitor (IC50: 5.8 nM and a Ki: 4.6 nM). PF-5274857 is a potentially attractive clinical candidate for the treatment of tumor t...
T2299 BMS-833923 XL-139 Apoptosis , Hedgehog/Smoothened , Smo
BMS-833923 (XL-139), an orally bioavailable Smoothened antagonist, inhibits BODIPY cyclopamine binding to SMO in a dose-dependent manner (IC50: 21 nM).
T9532 MRT-81 Others
MRT-81 inhibits human and rodent smoothened Smo receptors effectively with an IC50 value of 41 nM in the Shh-light2 cells. MRT-81 has potent hedgehog inhibiting activity. MRT-81 also can be used for the research of cance...
T1926 Sonidegib Erismodegib,NVP-LDE225,LDE225 Hedgehog/Smoothened , Smo
Sonidegib (Erismodegib), a Smoothened (Smo) antagonist, inhibits Hedgehog (Hh) signaling with IC50 of 1.3 nM (mouse) and 2.5 nM (human), respectively.
T0107 Halcinonide Halcimat,Halciderm,Halcinonida,SQ-18566 Glucocorticoid Receptor , Smo
Halcinonide (Halciderm), a high-efficiency corticosteroid, is served as an anti-inflammatory agent used in topical preparations.
T2250 DY131 DY 131,GSK 9089,DY-131 Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Smo
DY131 (DY-131) is a novel selective agonist of ERRβ and ERRγ.
T15727 Sonidegib diphosphate NVP-LDE 225 diphosphate,Erismodegib diphosphate,LDE225 diphosphate Smo
Sonidegib diphosphate (LDE225 diphosphate) is an effective and selective Smo antagonist (IC50: 1.3 nM and 2.5 nM for mouse and human Smo in a binding assay, respectively).
T124384 Jasmonic acid (-)-Jasmonic acid
Jasmonic acid (JA) is a phytohormone and plant growth regulator involved in plant defense and growth and development.Jasmonic acid plays an important role in signaling, inducing the MAP kinase cascade pathway and calcium...
T2590 Vismodegib Erivedge,GDC-0449,RG 3616 Hedgehog/Smoothened , ABC , Autophagy
Vismodegib (GDC-0449) is a hedgehog pathway inhibitor (IC50: 3 nM). It also inhibits P-gp (IC50: 3.0 μM), ABCG2 (IC50: 1.4 μM).
T5144 Desmopressin acetate (16679-58-6 free base) Desmopressin acetate,DDAVP Vasopressin Receptor
Desmopressin acetate (16679-58-6 free base) (DDAVP) is the synthetic analog of the antidiuretic hormone arginine vasopressin. Vasopressin Receptor The antidiuretic properties of desmopressin have led to its use in polyur...
T5019 Desmopressin DDAVP,Desmopressin Acetate Vasopressin Receptor
Desmopressin (DDAVP)(DDAVP) is the synthetic analogue of the antidiuretic hormone arginine vasopressin.Vasopressin Receptor The antidiuretic properties of desmopressin have led to its use in polyuric conditions including...
T39910 Desmorpholinyl Navitoclax-NH-Me Desmorpholinyl ABT-263-NH-Me,Desmorpholinyl Navitoclax-NH-Me BCL
Desmorpholinyl Navitoclax-NH-Me (Desmorpholinyl ABT-263-NH-Me) is a Bcl-xL inhibitor, which can be employed alongside a CRBN ligand to synthesize XZ739, a PROTAC BCL-XL degrader [1] [2].
T39818 Desmorpholinyl Quizartinib-PEG2-COOH Desmorpholinyl Quizartinib-PEG2-COOH
Desmorpholinyl Quizartinib-PEG2-COOH is a compound featuring an FLT-3 ligand and a PEG-based PROTAC linker. It is employed in the synthesis of PROTAC FLT-3 degrader 1, which serves as a degrader for the FLT-3 internal ta...
T131458 Acetyl-alpha-desmotroposantonin
Acetyl-alpha-desmotroposantonin is a useful organic compound for research related to life sciences and the catalog number is T131458.
T13523 Bronchospasmolytic agent 1 Others
Bronchospasmolytic agent 1 is a flutropium bromide compound and acts as a bronchospasmolytic agent.
T23769 AZSMO-23 AZSMO 23
AZSMO-23 is the human ether-a-go-go-related gene (hERG)-encoded potassium channel activator that acts by blocking hKv4.3-hKChIP2.2, hCav3.2, and hKv1.5 and activating hCav1.2/β2/α2δ.
T131459 Alpha-Desmotroposantonin methylether
alpha-Desmotroposantonin methylether is a useful organic compound for research related to life sciences and the catalog number is T131459.
T32269 Jasmone, (E)- EINECS 228-410-7
Jasmone, (E)- is a type of perfuming agent.
T31472 Dihydrojasmone lactone gamma-Methyldecalactone,gamma-Methyl decalactone,4-Methyldecanolide
Dihydrojasmone lactone is a biochemical.
T74190 (-)-Jasmonoyl-L-isoleucine
(-)-Jasmonoyl-L-isoleucine ((-)-JA-L-Ile), an enantiomer of (+)-JA-L-Ile [1], is an inactive endogenous hormone.
T40880 (±)-Jasmonic acid
(±)-Jasmonic acid, a plant growth regulator and derivative of α-linolenic acid, exhibits chlorophyll-lowering effects in green and etiolated barley leaf segments, while also inhibiting the elongation of rice seedlings.
T65308 Methyl jasmonate
Methyl jasmonate is a useful organic compound for research related to life sciences. The catalog number is T65308 and the CAS number is 1211-29-6.
T36941 Sporidesmolide III
Sporidesmolide III is a cyclodepsipeptide originally isolated from P. chartarum.
T40465 SAG dihydrochloride Hedgehog/Smoothened
SAG dihydrochloride, a powerful agonist of the Smoothened (Smo) receptor (EC 50 = 3 nM; Kd = 59 nM), effectively activates the Hedgehog signaling pathway. It also negates the effects of Cyclopamine inhibition on Smo.
T4211 SAG hydrochloride (912545-86-9(free base)) Smoothened Agonist HCl Hedgehog/Smoothened
SAG hydrochloride (912545-86-9(free base)) (Smoothened Agonist HCl) acts as an SMO agonist.
T24754 Hh-Ag1.5 SAG-1.5,SAG1.5,SAG 1.5 Hedgehog/Smoothened
Hh-Ag1.5 (SAG-1.5) is a potent Hedgehog (Hh) agonist (EC50: 1 nM) and Smoothened (Smo) receptor agonist, with an EC50 of 1 nM and Ki values between 0.5 and 2.3 nM for Smo. Hh-Ag1.5-mediated reprogramming breaks the quies...
T64351 GI-560192 RL-0070933 Smo
GI-560192 (RL-0070933) is a potent smo cilial modulator with an EC50 value of 0.02 µM. GI-560192 modulates the translocation and/or accumulation of smoothened to the primary cilia by hedgehog signaling pathway.
T15019L CUR61414 hydrochloride CUR61414 hydrochloride (334998-36-6 Free base) Hedgehog/Smoothened
CUR61414 hydrochloride is a potent and cell permeable inhibitor of Hedgehog signaling pathway (IC50 =100-200 nM). CUR61414 hydrochloride is a small-molecule aminoproline class compound. CUR61414 hydrochloride selectively...
T70178 Sonidegib metabolite M25
Sonidegib metabolite M25 is a smoothened (SMO) antagonist.
T22958 M 25 Others
M 25 is a Smoothened (Smo) receptor antagonist.
T26723 AZD8542 AZD-8542,AZD 8542
AZD8542 is an antagonist of Smoothened (SMO) with potential as an oncology therapeutic.
T35539 IHR-Cy3 IHR-Cy3
Potent fluorescent Smo antagonist (IC50 = 100 nM). Non-fluorescent analog also available. Fan et al (2014) The Hedgehog pathway effector smoothened exhibits signaling competency in the absence of ciliary accumulation. Ch...
T35563 PF-5274857 hydrochloride
PF-5274857 hydrochloride is a potent, orally active, selective, blood-brain barrier permeable Smo antagonist with IC50=5.8 nM and Ki=4.6 nM. It has research potential in a variety of tumors including brain tumors and bra...

Compounds

SMO-IN-2
T63429
Synonym:
Target: Hedgehog/Smoothened
SMO-IN-3
T63387
Synonym:
Target:
SMO-IN-1
T61897
Synonym:
Target:
HhAntag
T3460
Synonym:
Target: Hedgehog/Smoothened, Smo
MRT-10
T23027
Synonym:
Target: Hedgehog/Smoothened
ALLO-2
T14188
Synonym:
Target: Hedgehog/Smoothened, Smo
MRT-83
T12109
Synonym:
Target: Smo
SANT-1
T2450
Synonym: SANT 1
Target: Hedgehog/Smoothened, Smo
MRT-14
T9531
Synonym:
Target: Smo
MK-4101
T6891
Synonym:
Target: Apoptosis, Hedgehog/Smoothened, Smo
Taladegib
T2666
Synonym: LY2940680
Target: Hedgehog/Smoothened, Smo
Glasdegib
T6514
Synonym: PF-04449913
Target: Hedgehog/Smoothened, Smo
Purmorphamine
T1810
Synonym: Shh Signaling Antagonist VI
Target: Hedgehog/Smoothened, Smo, Autophagy
IHR-1
T24159
Synonym: IHR 1
Target: Smo
SAG
T1779
Synonym: Smoothened Agonist (SAG) HCl,Smoothened Agonist
Target: Hedgehog/Smoothened, Smo
LEQ506
T11838
Synonym: NVP-LEQ506
Target: Smo
GSA-10
T22814
Synonym:
Target: Hedgehog/Smoothened
PF-5274857
T5465
Synonym: PF-5274857 freebase
Target: Smo
BMS-833923
T2299
Synonym: XL-139
Target: Apoptosis, Hedgehog/Smoothened, Smo
MRT-81
T9532
Synonym:
Target: Others
Sonidegib
T1926
Synonym: Erismodegib,NVP-LDE225,LDE225
Target: Hedgehog/Smoothened, Smo
Halcinonide
T0107
Synonym: Halcimat,Halciderm,Halcinonida,SQ-18566
Target: Glucocorticoid Receptor, Smo
DY131
T2250
Synonym: DY 131,GSK 9089,DY-131
Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Smo
Sonidegib diphosphate
T15727
Synonym: NVP-LDE 225 diphosphate,Erismodegib diphosphate,LDE225 diphosphate
Target: Smo
Jasmonic acid
T124384
Synonym: (-)-Jasmonic acid
Target:
Vismodegib
T2590
Synonym: Erivedge,GDC-0449,RG 3616
Target: Hedgehog/Smoothened, ABC, Autophagy
Desmopressin acetate (16679-58-6 free base)
T5144
Synonym: Desmopressin acetate,DDAVP
Target: Vasopressin Receptor
Desmopressin
T5019
Synonym: DDAVP,Desmopressin Acetate
Target: Vasopressin Receptor
Desmorpholinyl Navitoclax-NH-Me
T39910
Synonym: Desmorpholinyl ABT-263-NH-Me,Desmorpholinyl Navitoclax-NH-Me
Target: BCL
Desmorpholinyl Quizartinib-PEG2-COOH
T39818
Synonym: Desmorpholinyl Quizartinib-PEG2-COOH
Target:
Acetyl-alpha-desmotroposantonin
T131458
Synonym:
Target:
Bronchospasmolytic agent 1
T13523
Synonym:
Target: Others
AZSMO-23
T23769
Synonym: AZSMO 23
Target:
alpha-Desmotroposantonin methylether
T131459
Synonym:
Target:
Jasmone, (E)-
T32269
Synonym: EINECS 228-410-7
Target:
Dihydrojasmone lactone
T31472
Synonym: gamma-Methyldecalactone,gamma-Methyl decalactone,4-Methyldecanolide
Target:
(-)-Jasmonoyl-L-isoleucine
T74190
Synonym:
Target:
(±)-Jasmonic acid
T40880
Synonym:
Target:
Methyl jasmonate
T65308
Synonym:
Target:
Sporidesmolide III
T36941
Synonym:
Target:
SAG dihydrochloride
T40465
Synonym:
Target: Hedgehog/Smoothened
SAG hydrochloride (912545-86-9(free base))
T4211
Synonym: Smoothened Agonist HCl
Target: Hedgehog/Smoothened
Hh-Ag1.5
T24754
Synonym: SAG-1.5,SAG1.5,SAG 1.5
Target: Hedgehog/Smoothened
GI-560192
T64351
Synonym: RL-0070933
Target: Smo
CUR61414 hydrochloride
T15019L
Synonym: CUR61414 hydrochloride (334998-36-6 Free base)
Target: Hedgehog/Smoothened
Sonidegib metabolite M25
T70178
Synonym:
Target:
M 25
T22958
Synonym:
Target: Others
AZD8542
T26723
Synonym: AZD-8542,AZD 8542
Target:
IHR-Cy3
T35539
Synonym: IHR-Cy3
Target:
PF-5274857 hydrochloride
T35563
Synonym:
Target:
1 2
Cat No. Product Name Synonyms Targets
T2825 Cyclopamine 11-Deoxojervine Hedgehog/Smoothened , Endogenous Metabolite , Smo
Cyclopamine (11-Deoxojervine), a Smoothened (Smo) antagonist (IC50: 46 nM in TM3Hh12 cells), belongs to the group of steroidal jerveratrum alkaloids.
T3912 Saikosaponin B1 Others
Saponin activator. Activates release of Prostaglandin E2 in vitro. Anti-inflammatory agent. Orally active. Active in vivo and in vitro.
T3363 Jervine Iervin,11-Ketocyclopamine,Jerwiny Hedgehog/Smoothened , Smo
The biological activity of Jervine (Jerwiny) is mediated via its interaction with the 7 passes transmembrane protein Smoothened. Jervine binds with and inhibits smoothened, which is an integral part of the Hedgehog signa...
T6S2247 Alismoxide (+)-Alismoxide Others
1. Alismoxide ((+)-Alismoxide) has anti-inflammatory effects.
TJS0161 Eudesmol β-Eudesmol Others
β-Eudesmol (β-Eudesmol) is a natural product
T3865 Beta-Eudesmol Beta-Selinenol TRP/TRPV Channel , AChR
beta-Eudesmol (Beta-Selinenol) is a noncompetitive antagonist of nicotinic acetylcholine receptors (nAChRs). It is a sesquiterpene that has been found in a variety of plants, including Cannabis, and has diverse biologica...
T2783 Methyl dihydrojasmonate Methyl Dihydrojasmonate,Kharismal,Hedione Others
Methyl dihydrojasmonate (Kharismal) is an ester and a diffusive aroma compound, with the smell vaguely similar to jasmine. In racemic mixtures the odor is floral and citrus while epimerized mixtures exhibit a dense fatty...
T7220 Prohydrojasmon racemate Propyl dihydrojasmonate,Prohydrojasmon Others
Prohydrojasmon racemate (Propyl dihydrojasmonate) is a synthesized plant gowth regulator, which has jasmonic acid activity.
T19711 Desmosterol Desmesterol,24-Dehydrocholesterol Endogenous Metabolite
Desmosterol (24-Dehydrocholesterol) is a cholesterol biosynthesis intermediate that inhibits macrophage inflammatory vesicle activation and prevents vascular inflammation and atherosclerosis.
T8076 Cis-​Jasmone Jasmone Others
cis-​Jasmone is a natural product isolated from the volatile portion of the oil from jasmine flowers,as an insect semiochemical and in plant defense
T8077 Dihydrojasmone Others
Dihydrojasmone is a natural product from bergamot
T4900 (±)-Methyl Jasmonate (±)-Jasmonic Acid methyl ester,Methyl 2-(3-oxo-2-(pent-2-en-1-yl)cyclopentyl)acetate Others , Endogenous Metabolite
Methyl 2-(3-oxo-2-(pent-2-en-1-yl)cyclopentyl)acetate ((±)-Jasmonic Acid methyl ester)induces the synthesis of proteinase inhibitors in plant leaves. In cancer cells, it suppresses proliferation and induces apoptosis. Mo...
TN5801 12-Hydroxyjasmonic acid
12-Hydroxyjasmonic acid glucoside is a COI1-JAZ-independent activator of leaf-closing movement in samanea saman.
TN5886 Thamnosmonin
Thamnosmonin is a natural product from Citrus sinensis.
T83460 11-O-β-D-glucopyranosyl thamnosmonin
11-O-β-D-glucopyranosyl thamnosmonin is a coumarin glucoside extractable from the roots of Angelica apaensis that exhibits weak inhibitory effects on rabbit platelet aggregation induced by PAF, AA, and ADP [1].
TN2668 1beta-Hydroxy-beta-eudesmol Others
1beta-Hydroxy-beta-eudesmol is a natural product from Cymbopogon proximus STAPF.
T21296 Desmopressin acetate trihydrate Desmogalen,Adiuretin,Deamino Arginine Vasopressin,Vasopressin 1-Desamino-8-arginine
Desmopressin acetate is a synthetic replacement for vasopressin, which reduces urine production. Medical use of Desmopressin acetate includes: (a) bed wetting; (b) diabetes insipidus; (c) nighttime urination; (d) clottin...
T40450 Dihydrojasmonic acid
Dihydrojasmonic acid is a plant growth regulator.
TN1367 Alismol Potassium Channel , Calcium Channel , PI3K
Alismol has antihypertensive action, it decreases cardiac output, heart rate and left ventricular pressure, but it increases coronary flow, it has been used for the prevention of anginal attacks.
TN3962 Epi-Eudesmol Others
epi-Eudesmol is a natural product from Laggera alata var. montana C. D. Adams.
TN4351 Jasmoside Others
Jasmoside is a natural product from Jasminum mesnyi.
TSP-41868968 Alpha-Desmotroposantonin
alpha-Desmotroposantonin is a useful organic compound for research related to life sciences and the catalog number is TSP-41868968.
TN5377 Nardoeudesmol A
Nardoeudesmol A is a natural product for research related to life sciences. The catalog number is TN5377 and the CAS number is 1445952-30-6.
T19782 Antidesmone
Antidesmone is one compound mainly isolated from Ajugade cumbers Thunb (Labiatae). Antidesmone prevents acute lung injury via regulating MAPK and NF-κB activities.
TN2585 11-Hydroxyjasmonic acid Others
11-Hydroxyjasmonic acid is a natural product of Stephania, Menispermaceae. The catalog number is TN2585 and the CAS number is 140447-14-9. 11-Hydroxyjasmonic acid can be used as a reference standard.
T81113 Sporidesmolide V
Sporidesmolide V, a cyclodepsipeptide, has been isolated from Pithornyces chartarum cultures [1].
T10085 20(S)-Hydroxycholesterol 20α-Hydroxycholesterol Smo
20(S)-Hydroxycholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo).

Natural Products

Cyclopamine
T2825
Synonym: 11-Deoxojervine
Target: Hedgehog/Smoothened, Endogenous Metabolite, Smo
Saikosaponin B1
T3912
Synonym:
Target: Others
Jervine
T3363
Synonym: Iervin,11-Ketocyclopamine,Jerwiny
Target: Hedgehog/Smoothened, Smo
Alismoxide
T6S2247
Synonym: (+)-Alismoxide
Target: Others
Eudesmol
TJS0161
Synonym: β-Eudesmol
Target: Others
beta-Eudesmol
T3865
Synonym: Beta-Selinenol
Target: TRP/TRPV Channel, AChR
Methyl dihydrojasmonate
T2783
Synonym: Methyl Dihydrojasmonate,Kharismal,Hedione
Target: Others
Prohydrojasmon racemate
T7220
Synonym: Propyl dihydrojasmonate,Prohydrojasmon
Target: Others
Desmosterol
T19711
Synonym: Desmesterol,24-Dehydrocholesterol
Target: Endogenous Metabolite
cis-​Jasmone
T8076
Synonym: Jasmone
Target: Others
Dihydrojasmone
T8077
Synonym:
Target: Others
(±)-Methyl Jasmonate
T4900
Synonym: (±)-Jasmonic Acid methyl ester,Methyl 2-(3-oxo-2-(pent-2-en-1-yl)cyclopentyl)acetate
Target: Others, Endogenous Metabolite
12-Hydroxyjasmonic acid
TN5801
Synonym:
Target:
Thamnosmonin
TN5886
Synonym:
Target:
11-O-β-D-glucopyranosyl thamnosmonin
T83460
Synonym:
Target:
1beta-Hydroxy-beta-eudesmol
TN2668
Synonym:
Target: Others
Desmopressin acetate trihydrate
T21296
Synonym: Desmogalen,Adiuretin,Deamino Arginine Vasopressin,Vasopressin 1-Desamino-8-arginine
Target:
Dihydrojasmonic acid
T40450
Synonym:
Target:
Alismol
TN1367
Synonym:
Target: Potassium Channel, Calcium Channel, PI3K
epi-Eudesmol
TN3962
Synonym:
Target: Others
Jasmoside
TN4351
Synonym:
Target: Others
alpha-Desmotroposantonin
TSP-41868968
Synonym:
Target:
Nardoeudesmol A
TN5377
Synonym:
Target:
Antidesmone
T19782
Synonym:
Target:
11-Hydroxyjasmonic acid
TN2585
Synonym:
Target: Others
Sporidesmolide V
T81113
Synonym:
Target:
20(S)-Hydroxycholesterol
T10085
Synonym: 20α-Hydroxycholesterol
Target: Smo

Recombinant Proteins

Species：
Human (9)
Plasmodium falciparum (7)
Mouse (5)
Rat (2)
Nicotiana tabacum (1)
Plasmodium berghei (1)
Plasmodium knowlesi (1)
Expression System：
E. coli (12)
HEK293 (11)
Baculovirus (1)
Yeast (1)
in vitro E. coli expression system (1)
Tag：
His (6)
N-terminal 10xHis-tagged and C-terminal Myc-tagged (3)
N-terminal 6xHis-SUMO-tagged (3)
hFc (3)
C-His (2)
N-terminal 10xHis-tagged (2)
N-terminal 6xHis-tagged (2)
None (2)
Tag-Free (2)
N-terminal 6xHis-GST-tagged (1)
Cat No. Product Name Species Expression System
TMPH-03144 SEY1 Protein, Plasmodium knowlesi, Recombinant (His) Plasmodium knowlesi in vitro E. coli expression system
Probable GTP-binding protein that may be involved in cell development.
TMPH-03143 PFD0110w Protein, Plasmodium falciparum, Recombinant Plasmodium falciparum E. coli
During the asexual blood stage, binds to a sialic acid containing receptor on the surface of the host erythrocyte and thus is involved in merozoite invasion. Binds erythrocytes via a neuraminidase sensitive and trypsin-,...
TMPH-03138 GST Protein, Plasmodium falciparum, Recombinant (His) Plasmodium falciparum Yeast
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. May also function as a storage protein or ligandin for parasitotoxic ferriprotoporphyrin IX (hemin).
TMPH-03061 Osmotin Protein, Nicotiana tabacum, Recombinant (His & SUMO) Nicotiana tabacum E. coli
TMPH-03142 Plasmepsin-2 Protein, Plasmodium falciparum, Recombinant (E. coli, His & Myc) Plasmodium falciparum E. coli
During the asexual blood stage, participates in initial cleavage of native host hemoglobin (Hb) resulting in Hb denaturation. May cleave preferentially denatured hemoglobin that has been cleaved by PMI. Digestion of host...
TMPH-02128 SMOC1 Protein, Human, Recombinant (GST & His) Human E. coli
Plays essential roles in both eye and limb development. Probable regulator of osteoblast differentiation.
TMPH-03137 PFS230 Protein, Plasmodium falciparum, Recombinant Plasmodium falciparum E. coli
Gametocyte surface protein required for male/female gamete fusion. Also required for male gamete exflagellation and interaction with erythrocytes.
TMPH-03139 MDR1 Protein, Plasmodium falciparum, Recombinant (His & SUMO) Plasmodium falciparum E. coli
Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
TMPY-01892 Desmocollin 2/DSC2 Protein, Human, Recombinant (His) Human HEK293
DSC2 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. Like other desmocollins, murine DSC2 has two products, Dsc2a and Dsc2b, produced by alternative splicing...
TMPY-03370 Desmocollin 2/DSC2 Protein, Rat, Recombinant (His) Rat HEK293
DSC2 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. Like other desmocollins, murine DSC2 has two products, Dsc2a and Dsc2b, produced by alternative splicing...
TMPY-04642 Desmocollin 2/DSC2 Protein, Rat, Recombinant (hFc) Rat HEK293
DSC2 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. Like other desmocollins, murine DSC2 has two products, Dsc2a and Dsc2b, produced by alternative splicing...
TMPY-01783 SMOC1 Protein, Human, Recombinant (His) Human HEK293
SPARC-related modular calcium-binding protein 1, also known as secreted modular calcium-binding protein 1 and SMOC1, is a member of the SPARC family. SMOC1 is widely expressed in many tissues with a strongest signal in o...
TMPH-03140 Plasmepsin-1 Protein, Plasmodium falciparum, Recombinant (His) Plasmodium falciparum E. coli
During the asexual blood stage, catalyzes the initial cleavage of native host hemoglobin (Hb) resulting in Hb denaturation; specifically cleaves between Phe-33 and Leu-34 of Hb alpha-chain. Digestion of host Hb is an ess...
TMPK-00967 DSG-2/Desmoglein-2 Protein, Human, Recombinant (His) Human HEK293
Desmoglein-2 (DSG-2) as the primary high-affinity receptor used by adenoviruses Ad3, Ad7, Ad11 and Ad14. These serotypes represent key human pathogens causing respiratory and urinary tract infections. In epithelial cells...
TMPK-00736 DSG-2/Desmoglein-2 Protein, Mouse, Recombinant (His) Mouse HEK293
Desmoglein-2 (DSG-2) as the primary high-affinity receptor used by adenoviruses Ad3, Ad7, Ad11 and Ad14. These serotypes represent key human pathogens causing respiratory and urinary tract infections. In epithelial cells...
TMPH-03136 L-lactate dehydrogenase Protein, Plasmodium berghei, Recombinant (His & Myc) Plasmodium berghei E. coli
L-lactate dehydrogenase Protein, Plasmodium berghei, Recombinant (His & Myc) is expressed in E. coli.
TMPH-03141 Plasmepsin-2 Protein, Plasmodium falciparum, Recombinant (His & Myc) Plasmodium falciparum Baculovirus
During the asexual blood stage, participates in initial cleavage of native host hemoglobin (Hb) resulting in Hb denaturation. May cleave preferentially denatured hemoglobin that has been cleaved by PMI. Digestion of host...
TMPH-02540 GRK2 Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to...
TMPH-01528 IHH Protein, Human, Recombinant (His) Human E. coli
Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target gen...
TMPY-01798 Frizzled 10 Protein, Mouse, Recombinant (His) Mouse HEK293
Frizzled-1, also known as Fz-1, CD35 and FZD1, is a multi-pass membrane protein which belongs to theG-protein coupled receptor Fz/Smo family. Frizzled-1 / FZD1 is abundantly expressed in the cerebellum, followed by ce...
TMPY-04140 Frizzled 10 Protein, Human, Recombinant (hFc) Human HEK293
Frizzled-1, also known as Fz-1, CD35 and FZD1, is a multi-pass membrane protein which belongs to theG-protein coupled receptor Fz/Smo family. Frizzled-1 / FZD1 is abundantly expressed in the cerebellum, followed by ce...
TMPY-01165 FZD1/Frizzled 1 Protein, Mouse, Recombinant (His) Mouse HEK293
Frizzled-1, also known as FZD1, belongs to theG-protein coupled receptor Fz/Smo family. FZD1 contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-term...
TMPJ-01127 SHH Protein, Human, Recombinant Human E. coli
Sonic Hedgehog Homolog (SHH) belongs to a three-protein family called hedgehog. The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH). Hedgehog proteins are key signaling molecules in embryonic...
TMPJ-01128 SHH Protein, Human, Recombinant (C24II) Human E. coli
Sonic Hedgehog Homolog (SHH) belongs to a three-protein family called Hedgehog. The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH). Hedgehog proteins are key signaling molecules in embryonic...
TMPY-04147 Frizzled 10 Protein, Human, Recombinant (His) Human HEK293
Frizzled-1, also known as Fz-1, CD35 and FZD1, is a multi-pass membrane protein which belongs to theG-protein coupled receptor Fz/Smo family. Frizzled-1 / FZD1 is abundantly expressed in the cerebellum, followed by ce...
TMPY-01797 Frizzled 10 Protein, Mouse, Recombinant (hFc) Mouse HEK293
Frizzled-1, also known as Fz-1, CD35 and FZD1, is a multi-pass membrane protein which belongs to theG-protein coupled receptor Fz/Smo family. Frizzled-1 / FZD1 is abundantly expressed in the cerebellum, followed by ce...
SEY1 Protein, Plasmodium knowlesi, Recombinant (His)
TMPH-03144
Species: Plasmodium knowlesi
Expression System: in vitro E. coli expression system
PFD0110w Protein, Plasmodium falciparum, Recombinant
TMPH-03143
Species: Plasmodium falciparum
Expression System: E. coli
GST Protein, Plasmodium falciparum, Recombinant (His)
TMPH-03138
Species: Plasmodium falciparum
Expression System: Yeast
Osmotin Protein, Nicotiana tabacum, Recombinant (His & SUMO)
TMPH-03061
Species: Nicotiana tabacum
Expression System: E. coli
Plasmepsin-2 Protein, Plasmodium falciparum, Recombinant (E. coli, His & Myc)
TMPH-03142
Species: Plasmodium falciparum
Expression System: E. coli
SMOC1 Protein, Human, Recombinant (GST & His)
TMPH-02128
Species: Human
Expression System: E. coli
PFS230 Protein, Plasmodium falciparum, Recombinant
TMPH-03137
Species: Plasmodium falciparum
Expression System: E. coli
MDR1 Protein, Plasmodium falciparum, Recombinant (His & SUMO)
TMPH-03139
Species: Plasmodium falciparum
Expression System: E. coli
Desmocollin 2/DSC2 Protein, Human, Recombinant (His)
TMPY-01892
Species: Human
Expression System: HEK293
Desmocollin 2/DSC2 Protein, Rat, Recombinant (His)
TMPY-03370
Species: Rat
Expression System: HEK293
Desmocollin 2/DSC2 Protein, Rat, Recombinant (hFc)
TMPY-04642
Species: Rat
Expression System: HEK293
SMOC1 Protein, Human, Recombinant (His)
TMPY-01783
Species: Human
Expression System: HEK293
Plasmepsin-1 Protein, Plasmodium falciparum, Recombinant (His)
TMPH-03140
Species: Plasmodium falciparum
Expression System: E. coli
DSG-2/Desmoglein-2 Protein, Human, Recombinant (His)
TMPK-00967
Species: Human
Expression System: HEK293
DSG-2/Desmoglein-2 Protein, Mouse, Recombinant (His)
TMPK-00736
Species: Mouse
Expression System: HEK293
L-lactate dehydrogenase Protein, Plasmodium berghei, Recombinant (His & Myc)
TMPH-03136
Species: Plasmodium berghei
Expression System: E. coli
Plasmepsin-2 Protein, Plasmodium falciparum, Recombinant (His & Myc)
TMPH-03141
Species: Plasmodium falciparum
Expression System: Baculovirus
GRK2 Protein, Mouse, Recombinant (His & SUMO)
TMPH-02540
Species: Mouse
Expression System: E. coli
IHH Protein, Human, Recombinant (His)
TMPH-01528
Species: Human
Expression System: E. coli
Frizzled 10 Protein, Mouse, Recombinant (His)
TMPY-01798
Species: Mouse
Expression System: HEK293
Frizzled 10 Protein, Human, Recombinant (hFc)
TMPY-04140
Species: Human
Expression System: HEK293
FZD1/Frizzled 1 Protein, Mouse, Recombinant (His)
TMPY-01165
Species: Mouse
Expression System: HEK293
SHH Protein, Human, Recombinant
TMPJ-01127
Species: Human
Expression System: E. coli
SHH Protein, Human, Recombinant (C24II)
TMPJ-01128
Species: Human
Expression System: E. coli
Frizzled 10 Protein, Human, Recombinant (His)
TMPY-04147
Species: Human
Expression System: HEK293
Frizzled 10 Protein, Mouse, Recombinant (hFc)
TMPY-01797
Species: Mouse
Expression System: HEK293
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