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Anti-WAS Monoclonal Antibody (3I479)
(Synonyms: WASP, THC1, THC, SCNX, IMD2) Copy Product Info
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Synonyms: WASP, THC1, THC, SCNX, IMD2
Catalog No. TMAT-1037 Copy Product Info
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Anti-WAS Monoclonal Antibody (3I479) is a Mouse antibody targeting WAS. Anti-WAS Monoclonal Antibody (3I479) can be used in IHC,FCM.
Anti-WAS Monoclonal Antibody
(3I479)
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Product Introduction
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Related Conjugates and Formulations
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| Description | Anti-WAS Monoclonal Antibody (3I479) is a Mouse antibody targeting WAS. Anti-WAS Monoclonal Antibody (3I479) can be used in IHC,FCM. |
| Synonyms | WASP, THC1, THC, SCNX, IMD2 |
| Ig Type | IgG2a |
| Clone | 3I479 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in WAS patients. A transcript variant arising as a result of alternative promoter usage, and containing a different 5' UTR sequence, has been described, however, its full-length nature is not known. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human WAS (AA: 57-170) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | WAS |
| Gene ID | |
| Protein Name | Actin nucleation-promoting factor WAS |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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