IAP

Expression system: E. coli
Length: 20-528, Full Length of Mature Protein
Activity: Not Tested

Expression system: HEK293 Cells
Length: 19-139, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 19-139, Partial
Activity: BLI

Expression system: HEK293 Cells
Length: 19-139, Partial
Activity: BLI

Expression system: HEK293 Cells
Length: 19-139, Partial
Activity: BLI

CD47 Protein, Rhesus macaque, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-90 KDa and the accession number is F7A802.

CD47, also known as Integrin‑Associated Protein (IAP) and OA3, is a glycosylated atypical member of the immunoglobulin superfamily. Mouse CD47 is an integral membrane protein that consists of a extracellular domain (ECD) with a single Ig‑like domain, five membrane-spanning regions with short intervening loops, and C‑terminal cytoplasmic tail. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It plays an important role in memory formation and synaptic plasticity in the hippocampus. As a receptor for SIRPA, it binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cellcell adhesion, it enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. It may play a role in membrane transport and or integrin dependent signal transduction. It also prevents premature elimination of red blood cells.

CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene. CD47 belongs to the immunoglobulin superfamily and partners with membrane integrins and also binds the ligands thrombospondin-1 (TSP-1) and signal-regulatory protein alpha (SIRPα).CD-47 acts as a don't eat me signal to macrophages of the immune system which has made it a potential therapeutic target in some cancers.

Alkaline phosphatase can be considered our favorite enzyme for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline phosphatase (Intestinal type) ALPI Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 53.10 kDa and the accession number is F8VPQ6.

Expression system: HEK293 Cells
Length: 20-503, Full Length of Mature Protein
Activity: SPR

Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyrosine phosphates on the surface of the magnetic nanoparticle and enable the magnetic nanoparticles to adhere selectively to the cancer cells, such as HeLa cells. Placental alkaline phosphatase (PLAP), encoded by the ALPP gene, is produced by the fetal side of the placenta.

Expression system: HEK293 Cells
Length: 1-503, Full Length of Mature Protein
Activity: Enzyme Activity

Expression system: HEK293 Cells
Length: 1-503, Full Length of Mature Protein
Activity: Enzyme Activity

Expression system: HEK293 Cells
Length: 1-139, Partial
Activity: ELISA

Expression system: HEK293 Cells
Length: 1-140, Partial
Activity: ELISA、SPR

Expression system: HEK293 Cells
Length: 1-139, Partial
Activity: ELISA、SPR、BLI

Expression system: HEK293 Cells
Length: 1-139, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 1-140, Partial
Activity: Not Tested

CD47 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 13.8 kDa and the accession number is E5Q371.

Expression system: HEK293 Cells
Length: 1-140, Partial
Activity: ELISA

CD47 Protein, Human, Recombinant (aa 19-139, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.17kDa and the accession number is NP_942088.1.

Expression system: HEK293 Cells
Length: 21-511, Full Length of Mature Protein
Activity: Enzyme activity

Expression system: HEK293 Cells
Length: 1-139, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 1-140, Partial
Activity: Not Tested