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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T21195 | AICAR monophosphate | Aica ribonucleotide,AICA riboside,Acadesine 5'-monophosphate,Z-nucleotide | Others |
AICAR monophosphate (Aica ribonucleotide) is a purine precursor with antineoplastic activity and can be used in studies about type 2 diabetes. | |||
T6357 | (S)-crizotinib | ent-crizotinib | Apoptosis , DNA/RNA Synthesis , MTH1 |
(S)-crizotinib (ent-crizotinib) (IC50 of 72 nM), an effective MTH1 (NUDT1) inhibitor, is the (S)-enantiomer of crizotinib. | |||
T9341 | Bemnifosbuvir | AT-511 | Others , HCV Protease , SARS-CoV |
Bemnifosbuvir (AT-511) is a novel phosphoramidate prodrug of 2'-fluoro-2'-C-methylguanosine-5'-monophosphate that has potent in vitro activity against HCV. | |||
T9331 | Bemnifosbuvir hemisulfate | AT-527 | HCV Protease , SARS-CoV |
Bemnifosbuvir hemisulfate (AT-527) is a potent inhibitor of HCV virus replication. | |||
T40192 | DGTP | 2'-Deoxyguanosine-5'-triphosphate | Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis |
dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, and 8-O-dGTP. | |||
T1675 | Adefovir dipivoxil | Hepsera,GS 0840,Preveon | Others , HBV , Reverse Transcriptase |
Adefovir dipivoxil (GS 0840) is a dipivoxil formulation of adefovir, a nucleoside reverse transcriptase inhibitor analog of adenosine with activity against hepatitis B virus (HBV), herpes virus, and human immunodeficienc... | |||
T2923 | Apremilast | CC-10004 | Apoptosis , TNF , PDE |
Apremilast (CC-10004) (CC-10004) is a potent and orally active PDE4 (IC50=74 nM) with anti-inflammation activities. | |||
T2535 | Ivabradine hydrochloride | S 16257-2,Ivabradine HCl | Adrenergic Receptor |
Ivabradine hydrochloride (S 16257-2) is a new If inhibitor (IC50: 2.9 μM). Ivabradine Hydrochloride is the hydrochloride salt form of ivabradine, an orally bioavailable, hyperpolarization-activated, cyclic nucleotide-gat... | |||
T7516 | ZD7288 | ICI D7288 | HCN Channel |
ZD7288 (ICI D7288), a selective hyperpolarization-activated cyclic nucleotide-gated channel blocker, inhibits hippocampal synaptic plasticity. | |||
T3280 | Clodronate disodium tetrahydrate | clodronic acid disodium tetrahydrate,Disodium clodronate tetrahydrate,Clastoban,Clodronate disodium | IL Receptor , TNF |
Clodronate disodium tetrahydrate (Clastoban) inhibits bone resorption and soft tissue calcification. | |||
T8855 | Polydeoxyribonucleotide(Sodium salt) | Polydeoxyribonucleotide from salmon | Others |
Polydeoxyribonucleotide can improve secretion of various growth factors, promote collagen synthesis, and restore tensile strength of the Achilles tendon in a rat model with Achilles tendon injury. | |||
T78408 | Nicotinamide 1,N6-ethenoadenine dinucleotide | ε-NAD | |
Nicotinamide 1,N6-ethenoadenine dinucleotide (ε-NAD), a fluorescent NAD analogue, functions as a substrate in bacterial toxin-catalyzed G-ADP ribosylation of G-proteins involved in signal transduction. It is also applica... | |||
T77253 | β-Nicotinamide adenine dinucleotide reduced dipotassium | ||
β-Nicotinamide adenine dinucleotide reduced dipotassium is an orally active reduced coenzyme. β-Nicotinamide adenine dinucleotide reduced dipotassium is a donor of ADP-ribose units in ADP-ribosylaton reactions and a prec... | |||
T64590 | Flavin Adenine Dinucleotide DiSodium Salt xhydrate | ||
Flavin Adenine Dinucleotide DiSodium Salt xhydrate is a useful organic compound for research related to life sciences and the catalog number is T64590. | |||
T23969 | DCAI | Others | |
DCAI is an inhibitor of nucleotide exchange and nucleotide release acting by binding to the pocket adjacent to the Ras-SOS interface. | |||
T19214 | Bredinin aglycone | 5-Hydroxy-1H-imidazole-4-carboxamide,SM-108 | Others |
Bredinin aglycone (SM-108) is a purine nucleotide analog. It can be used to examine the efficiency of catalysts for the preparation of purine nucleotide analogs. | |||
T12814 | (S)-Tenofovir | (S)-PMPA,(S)-GS 1278,(S)-TDF | Others |
(S)-Tenofovir ((S)-PMPA) is the less active S-enantiomer of Tenofovir which is a nucleotide reverse transcriptase inhibitor. | |||
T7111 | Tenofovir Disoproxil | GS 4331,Bis(POC)-PMPA | HBV , HIV Protease , Reverse Transcriptase |
Tenofovir Disoproxil (GS 4331) is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B. | |||
T13995 | 1-Methyl-7-nitroisatoic anhydride | 1M7 | Others |
1-Methyl-7-nitroisatoic anhydride (1M7) is a reagent. It detects local nucleotide flexibility, for probing 2'-hydroxyl reactivity. | |||
T22592 | ATPγS tetralithium salt | ATP-gamma-S tetralithium salt | PERK |
ATPγS tetralithium salt is a substrate for nucleotide hydrolysis and RNA unraveling activity of the eukaryotic translation initiation factor eIF4A, associated with p97 mutants and prions. | |||
T19596 | UDP-GlcNAc Disodium Salt | Uridine 5′-diphospho-N-acetylglucosamine,UDP-α-D-N-Acetylglucosamine Disodium Salt | Others |
UDP-GlcNAc Disodium Salt (UDP-α-D-N-Acetylglucosamine Disodium Salt) is a nucleotide sugar. It is synthesized from glucose via the hexosamine biosynthetic pathway (HBP). | |||
T7282 | Tenofovir alafenamide hemifumarate | GS-7340 (hemifumarate),Tenofovir alafenamide fumarate | HIV Protease , Reverse Transcriptase |
Tenofovir alafenamide hemifumarate (GS-7340 hemifumarate) is an oral phosphonoamidate prodrug of the HIV reverse transcriptase nucleotide inhibitor tenofovir (TFV) | |||
T3587 | NOD-IN-1 | Compound 4 | NOD-like Receptor (NLR) , NOD |
NOD-IN-1 (Compound 4) is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors. | |||
T2409 | Tenofovir alafenamide | GS-7340 | HIV Protease , Reverse Transcriptase |
Tenofovir alafenamide (GS-7340) is a nucleotide reverse transcriptase inhibitor (NRTI) and a novel ester prodrug of the antiretroviral tenofovir. | |||
T7558 | CID-1067700 | Ras | |
CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases(Rab7 with a Ki of 13 nM). | |||
T2244 | ESI-09 | cAMP , Virus Protease | |
ESI-09 is a new-typel noncyclic nucleotide EPAC antagonist.The IC50 values of ESI-09 for EPAC1 and EPAC2 is 3.2 and 1.4 μM, respectively. | |||
T67817 | Besifovir PM | LB80331 PM | HBV |
Besifovir PM (LB80331 PM) is an analogue of Besifovir, a novel orally available acyclic nucleotide phosphonate for the treatment of chronic hepatitis B infection. | |||
T63290 | (R,1R)-Tenofovir amibufenamide | (R,1R)-HS-10234 | Antiviral |
(R,1R)-Tenofovir amibufenamide ((R,1R)-HS-10234) can be used as a Tenofovir prodrug, which can be taken orally and has antiviral activity. Tynofovir is a nucleotide reverse transcriptase inhibitor. | |||
T35648 | 4-Thiouridine | Others | |
4-Thiouridine (4-SU) is a photoactivatable ribonucleoside analog that is widely used for RNA analysis, including short-range RNA-RNA crosslinking and nascent RNA labeling. The crosslinking thio moiety is attached directl... | |||
T24154 | I942 | I 942,I-942 | cAMP |
I942 is a novel, selective ACyclic nucleotide (NCN) EPAC1 agonist that activates exchange proteins to regulate inflammatory gene expression in human umbilical blood tubes and inhibit pro-inflammatory cytokine signaling a... | |||
T12569L | PSB-12379 ditriethylamine salt | CD73 | |
PSB-12379 ditriethylamine salt, a nucleotide analogue, is a potent Ecto-5'-Nucleotidase (CD73) inhibitor with Kis of 9.03 nM (rat) and 2.21 nM (human). | |||
T36688 | Deoxyguanosine triphosphate trisodium salt | Deoxyguanosine 5-triphosphate,2'-Deoxyguanosine-5'-triphosphate trisodium salt,dGTP trisodium salt | Nucleoside Antimetabolite/Analog |
Deoxyguanosine triphosphate trisodium salt (2'-Deoxyguanosine-5'-triphosphate trisodium salt) is a nucleotide precursor for DNA synthesis in cells and can be used in the reverse transcription-polymerase chain reaction (R... | |||
T8798 | MSA-2 | STING | |
MSA-2 is a potent and orally available non-nucleotide STING agonist. | |||
TP2131L | Rac1 Inhibitor W56 acetate(1095179-01-3 free base) | Rho | |
Peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activation site of Rac1; selectively inhibits Rac1 interaction with Rac1-specific GEFs TrioN, GEF-H1 and Tiam1. | |||
T38361 | GSK717 | IL Receptor , NOD | |
GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signaling, with an IC50 of 400 nM for MDP-stimulated IL-8 secretio... | |||
T60904 | ERCC1-XPF-IN-2 | Others | |
ERCC1-XPF-IN-2 is active in nucleotide excision repair, cisplatin enhancement and γH2AX assays. ERCC1-XPF-IN-2 is a potent inhibitor of ERCC1-XPF endonuclease with an IC 50 value of 0.6 μM [1]. | |||
T10247 | Adenosine 5'-diphosphoribose sodium | Adenosine 5'-diphosphoribose sodium,ADP ribose sodium | Endogenous Metabolite , TRP/TRPV Channel , Autophagy |
Adenosine 5'-diphosphoribose sodium (ADP ribose sodium) is a metabolite of nicotinamide adenine nucleotide (NAD+), which is widely present in organisms.Adenosine 5'-diphosphoribose sodium (ADP ribose sodium) is a potent ... | |||
T33762 | Fosifloxuridine nafalbenamide | NUC-3373,NUC3373,NUC 3373 | DNA/RNA Synthesis |
Fosifloxuridine nafalbenamide (NUC 3373), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor. NUC-3373 has anticancer activity. NUC-3373 is a ProTide transformation of 5-FU that generates much higher c... | |||
T60109 | Protein kinase inhibitor H-7 | 5-(2-methylpiperazine-1-sulfonyl)isoquinoline,1-(5-Isoquinolinylsulfonyl)-2-methylpiperazine | PKC |
Protein kinase inhibitor H-7 (5-(2-methylpiperazine-1-sulfonyl)isoquinoline) is a potent inhibitor of protein kinase C (PKC) with a Ki of 6 μM. Protein kinase inhibitor H-7 is also a cyclic nucleotide dependent protein k... | |||
TQ0002 | A-317491 | ABT 202 | P2X Receptor |
A-317491 (ABT 202) is a non-nucleotide P2X3 ( Ki: 22 nM) and P2X2/3 receptor (Ki: 9 nM) antagonist, which inhibits calcium flux mediated by the receptors. | |||
T28946 | Tenofovir exalidex | Tenofovir,HDP-Tenofovir,CMX-157,CMX157,CMX 157 | Antiviral |
Tenofovir exalidex (CMX 157) is a lipid conjugate of the acyclic nucleotide analog Tenofovir with activity against both wild-type and antiretroviral drug-resistant HIV strains, including multidrug nucleoside/nucleotide a... | |||
T4132 | BPTU | BMS-646786 | P2Y Receptor |
BPTU (BMS-646786) is an allosteric antagonist of P2Y1 (EC50 = 0.06-0.3 μM). Non-nucleotide ligand. Binds receptor outside of the helical bundle. Blocks inhibition of spontaneous contraction of rat and mouse colon induced... | |||
T23164 | PIT | 2,2'-Pyridylisatogen tosylate | P2Y Receptor |
PIT (2,2'-Pyridylisatogen tosylate) is a specific and non-competitive antagonist of the Purinergic receptor P2Y1 with an IC50 of 0.14 μM for human P2Y1. PIT does not affect nucleotide binding and can be used in studies a... | |||
T8527 | CPYPP | Others | |
CPYPP is an inhibitor of DOCK2-Rac1 interaction. CPYPP binds to DOCK2 DHR-2 domain and inhibits the guanine nucleotide exchange factor (GEF) activity of DOCK2DHR-2 for Rac1 in a dose-dependent manner(IC50 : 22.8 µM). CPY... | |||
T2627 | Nolatrexed dihydrochloride | Thymitaq,AG 337 | DNA/RNA Synthesis |
Nolatrexed dihydrochloride (Thymitaq) is the dihydrochloride salt of nolatrexed, a water-soluble lipophilic quinazoline folate analog with antineoplastic activity. Nolatrexed occupies the folate binding site of thymidyla... | |||
T74041 | GDP-L-fucose | ||
GDP-L-fucose is a nucleotide sugar that is a key substrate for the biosynthesis of fucose oligosaccharides, providing the fucose moiety for the oligosaccharides.The formation of GDP-L-fucose occurs through two pathways, ... | |||
T27586 | IDX184 | IDX-184,IDX 184 | HCV Protease |
IDX184 is a potent, orally active, targeted HCV polymerase inhibitor and nucleoside polymerase.IDX184 effectively inhibits HCV polymerase (IC50=0.31 μM, Ki=52.3 nM). IDX184 is a liver-targeted nucleotide prodrug with ant... | |||
T67821 | GS-9191 PM | BCRP , Antiviral | |
GS-9191 PM is a novel antitumorviral compound, a bis-amide prodrug of the nucleotide analog 9-(2-phosphonomethoxyethyl)-N6-cyclopropyl-2,6-diaminopurine (cPrPMEDAP).GS-9191 PM is a potent inhibitor of MDR1 and BCRP.GS-91... | |||
T4535L | Etomoxir | (R)-(+)-Etomoxir | Antioxidant , CPT |
Etomoxir is a carnitine palmitoyltransferase 1a (CPT-1a) inhibitor that inhibits fatty acid oxidation by inhibiting CPT-1a and inhibits palmitate oxidation in humans, rats, and guinea pigs. Etomoxir has an inhibitory eff... | |||
T8930 | CID44216842 | KUC103479N-02 | CDK , Ras |
CID44216842 (KUC103479N-02) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T22446 | NADP disodium salt | Disodium NADP,Triphosphopyridine nucleotide disodium salt | Others |
NADP disodium salt (Disodium NADP) is a nicotinamide adenine dinucleotide. NADP disodium salt is a key redox cofactor for electron transfer in the metabolism, serves as an electron carrier in a number of reactions, being... | |||
T5067 | Flavin adenine dinucleotide disodium salt | Flavin Adenine Dinucleotide Disodium,FAD sodium salt,FAD-Na2 | Others , Endogenous Metabolite |
Flavin adenine dinucleotide disodium salt (FAD sodium salt) is a flavin dinucleotide that is synthesized when the AMP moiety from ATP is transferred onto riboflavin 5'-monophosphate. FAD functions as a coenzyme that faci... | |||
T4721 | β-Nicotinamide mononucleotide | β-NM | Others , Endogenous Metabolite |
β-Nicotinamide mononucleotide (β-NM) is an important intermediate metabolite in the nicotinate and nicotinamide metabolism pathway. Mammals predominantly use nicotinamide rather than nicotinic acid as a precursor for NAD... | |||
T65172 | Flavin adenine dinucleotide | FAD | Endogenous Metabolite |
Flavin adenine dinucleotide (FAD) is a REDOX cofactor, a protein cogroup, involved in a variety of metabolic reactions. | |||
T19477 | Nicotinic acid mononucleotide | Others | |
Nicotinic acid mononucleotide is formed from nicotinic acid (NA) via the nicotinic acid phosphoribosyltransferase in the biosynthesis of NAD+. | |||
T4832 | Cytosine | 6-Aminopyrimidin-2(1H)-one,4-Amino-2-hydroxypyrimidine,Cytosinimine | Endogenous Metabolite |
Cytosine (6-Aminopyrimidin-2(1H)-one) is a pyrimidine base that is a fundamental unit of nucleic acids. The deamination of cytosine alone is apparent and the nucleotide of cytosine is the prime mutagenic nucleotide in le... | |||
T4718 | Uridine 5'-monophosphate | Uridylic acid,UMP,Uridine phosphate,Uridine 5'-phosphoric acid,5'-Uridylic acid | Others , Endogenous Metabolite |
5'-Uridylic acid. A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position. Uridine 5'-monophosphate (Uridylic acid) is a nucleotide that is found in RNA. It is an es... | |||
T4685 | INOSINIC ACID | Inosine 5′-monophosphate,IMP,I-5'-P | Endogenous Metabolite |
Inosinic acid (IMP) is a purine nucleotide which has hypoxanthine as the base and one phosphate group esterified to the sugar moiety. Inosinic acid is a nucleotide present in muscle and other tissues. It is formed by the... | |||
T8393 | Uridine triphosphate trisodium salt | UTP, Trisodium Salt,Uridine 5'-triphosphate trisodium salt,Uridine triphosphate (trisodium salt) | Others |
Uridine triphosphate trisodium salt (UTP, Trisodium Salt) is a nucleotide. | |||
T14140 | Agaric acid | Agaricinic Acid | Mitochondrial Metabolism , AChR |
Agaricic acid is an adenine nucleotide translocase antagonist.It is obtained from various plants of the fungous tribe, i.e. Polyporus officinalis and Polyporus igniarius. Agaric acid (Agaricinic Acid) induces mitochondri... | |||
T4942 | Galactose 1-phosphate Potassium salt | α-D-Galactose-1-phosphate Dipotassium Pentahydrate | Others , Endogenous Metabolite |
Galactose 1-phosphate Potassium salt (α-D-Galactose-1-phosphate Dipotassium Pentahydrate) is an intermediate in the galactose metabolism and nucleotide sugars metabolism pathways. | |||
T5073 | Inosine 5'-monophosphate disodium salt hydrate | Inosine 5'-monophosphate disodium salt,5'-IMP-Na2,Disodium 5'-inosinate monohydrate | Others , Endogenous Metabolite |
Inosine 5'-monophosphate disodium salt hydrate (Inosine 5'-monophosphate disodium salt), or inosinic acid, is the ribonucleotide of hypoxanthine and the first nucleotide formed during purine synthesis. | |||
T19083 | 1-Methylinosine | N1-Methylinosine,Inosine, 1-methyl | Nucleoside Antimetabolite/Analog , Endogenous Metabolite |
1-Methylinosine (N1-Methylinosine) is a modified nucleotide found at position 37 in tRNA 3' to the anticodon of eukaryotic tRNA and has a role as a metabolite. | |||
T37635 | 2'-Deoxyadenosine-5'-triphosphate trisodium | dATP trisodium | DNA/RNA Synthesis , Endogenous Metabolite |
2'-Deoxyadenosine-5'-triphosphate trisodium (dATP trisodium) is a nucleotide that serves as a substrate for DNA polymerase, which is used in cells for DNA synthesis or replication. | |||
TMO2752 | Cytidine 5'-monophosphate | 5'-Cytidylic acid,5'-CMP,Cytidylic Acid | Others , Endogenous Metabolite |
Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide, one of the basic units that make up RNA. It consists of nucleobase cytosine, pentose ribose and phosphate groups. | |||
T3791 | Atractyloside A | AChR | |
Atractyloside is a glycoside of a kaurene type diterpene that is found in some plants including Atractylis gummifera (ATRACTYLIS); COFFEE; XANTHIUM, and CALLILEPIS. Toxicity is due to inhibition of adenine nucleotide tra... | |||
T8787 | Drotaverine hydrochloride | PDE | |
Drotaverine hydrochloride is a type 4 cyclic nucleotide phosphodiesterase (PDE4) inhibitor,and is an antispasmodic drug, used to enhance cervical dilation during childbirth. Drotaverine hydrochloride is structurally rela... | |||
T4824 | 5,6-Dimethyl-1H-benzo[d]imidazole | 5,6-Dimethylbenzimidazole | Others , Endogenous Metabolite |
5,6-Dimethyl-1H-benzo[d]imidazole (5,6-Dimethylbenzimidazole) is an intermediate in Riboflavin metabolism. Dimethylbenzimidazole is the second to last step for the synthesis of alpha-Ribazole. It is converted from Ribofl... | |||
T0853L | Adenosine 5'-monophosphate monohydrate | 5'-AMP,5'-AMP monohydrate,5'-Adenylic acid | AMPK , Adenosine Receptor , HSV |
Adenosine 5'-monophosphate monohydrate (5'-AMP) , also known as 5'-adenylic acid, is a nucleotide that is used as a monomer in RNA. It is an ester of phosphoric acid and the nucleoside adenosine. Adenosine 5'-monophospha... | |||
T4743 | Uridine 5′-diphosphoglucose disodium salt | UDP-Glucose sodium salt,UDPG sodium salt,UDP-α-D-Glucose sodium salt,Uridine 5'-diphosphoglucose disodium sal | Endogenous Metabolite , P2Y Receptor |
Uridine 5′-diphosphoglucose disodium salt (UDP-Glucose sodium salt) is an endogenous nucleotide sugar involved in glycosyltransferase reactions in Metabolism. It is an agonist of the P2Y14 receptor (EC50 = 0.35 μM). It c... | |||
T1083 | Theophylline | Theo-24,1,3-Dimethylxanthine | Endogenous Metabolite , HDAC , PDE , Adenosine Receptor , Autophagy |
Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3... | |||
T5270 | 5-Methylcytosine | Others , DNA/RNA Synthesis , Endogenous Metabolite | |
5-Methylcytosine is a methylated nucleotide base found in eukaryotic DNA. In animals, the DNA methylation of cytosine to form 5-methylcytosine is found primarily in the palindromic sequence CpG. In plants, the methylated... | |||
T1362 | Hypoxanthine | 6-Hydroxypurine,Purin-6-ol,Sarcine,Sarkin | Others , Endogenous Metabolite |
Hypoxanthine (Purin-6-ol), also known as purine-6-ol or Hyp, belongs to the class of organic compounds known as purines.Hypoxanthine is a naturally occurring purine derivative and a reaction intermediate in the metabolis... | |||
T4839 | Ac-Ala-OH | N-Acetylalanine,N-Acetyl-L-alanine | Others , Endogenous Metabolite |
Ac-Ala-OH (N-Acetyl-L-alanine) is a substrate for Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit, Myelin basic protein, GTP-binding nuclear protein Ran, Tropomyosin alpha 4 chain, HIV-1 Rev binding pro... | |||
T4826 | L-Histidine monohydrochloride monohydrat | Others , Endogenous Metabolite | |
Histidine (abbreviated as His or H) is an alpha-amino acid. The L-isomer is one of the 22 proteinogenic amino acids, i.e., the building blocks of proteins. It is classified as a charged, polar because of the hydrophilic ... | |||
T16397 | Ophiobolin A | Others | |
Ophiobolin A is a fungal metabolite and a phytotoxin and is an effective and irreversibly inhibitor of calmodulin-activated cyclic nucleotide phosphodiesterase (IC50: 9 μM). Ophiobolin A also has antimicrobial and antica... | |||
T16837 | SAICAR | Others | |
SAICAR is an intermediate of de novo purine nucleotide biosynthesis, activates pyruvate kinase isoform M2 (PKM2) in an isozyme-selective manner (EC50: 0.3 mM). | |||
T38415 | Adenosine 5′-monophosphoramidate sodium | ||
Adenosine 5′-monophosphoramidate sodium is a derivative of adenosine used as an intermediate for nucleotide synthesis. It significantly influences the accumulation of cyclic AMP. | |||
T19334 | Galactose 1-phosphate | Others | |
Galactose 1-phosphate is an intermediate in the galactose metabolism and nucleotide sugars. | |||
T75525 | UDP-rhamnose | UDP-L-rhamnose | Endogenous Metabolite |
UDP-rhamnose (UDP-L-rhamnose) is a sugar nucleotide widely found in plants and animals and is used in the synthesis of pectin in cell walls.UDP-rhamnose is recognised in fungi and is used in the synthesis of quercetin. | |||
T83789 | 7-Deazaadenosine-5'-O-diphosphate sodium | 7-CH-ADP,Tubercidin 5’-diphosphate,TuDP | |
7-Deazaadenosine-5'-O-diphosphate, a modified nucleotide and metabolite of tubercidin, is generated through phosphorylation of tubercidin and further undergoes phosphorylation to become the active metabolite 7-deazaadeno... | |||
T5079 | Adenosine 5'-diphosphate sodium salt | Adenosine-5'-diphosphate trisodium salt,ADP sodium salt | Others , Endogenous Metabolite |
Adenosine 5'-diphosphate sodium salt (ADP sodium salt) is an adenine nucleotide that is phosphorylated into ATP by ATPase. This phosphorylation is a key part of cellular homeostatis as it allows for energy storage and is... | |||
T75676 | Orotidine 5′-monophosphate trisodium | ||
Orotidine 5'-monophosphate trisodium is a pyrimidine nucleotide. Orotidine 5'-monophosphate trisodium is synthesized via the de novo synthesis pathway for DNA synthesis in a large number of microorganisms including M. tu... | |||
T36667 | 2'-Deoxyadenosine-5'-triphosphate | dATP,Deoxyadenosine 5-triphosphate | DNA/RNA Synthesis , Endogenous Metabolite |
2'-Deoxyadenosine-5'-triphosphate (Deoxyadenosine 5-triphosphate) (dATP) is a naturally occurring small molecule nucleotide used in cells for DNA synthesis or replication. 2'-Deoxyadenosine-5'-triphosphate (dATP) is a su... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03406 | NMNAT1 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
NMNAT, also known as NMNAT1, is a member of the Nicotinamide-nucleotide adenylyltransferases. It is widely expressed with high levels in skeletal muscle, heart, liver, and kidney. NMNAT appears to have the ability to pro... | |||
TMPJ-00473 | QPRTase Protein, Human, Recombinant (His) | Human | E. coli |
Nicotinate-Nucleotide Pyrophosphorylase (QPRT) belongs to the nadC/modD family. QPRT plays an improtant role in catabolism of quinolinate which acts as a potent endogenous exitotoxin to neurons. In addition, QPRT serves ... | |||
TMPY-02802 | GNG13 Protein, Human, Recombinant (His) | Human | E. coli |
GNG13 is a subunit of heterotrimeric G proteins which consist of alpha, beta, and gamma subunits. Heterotrimeric G proteins are membrane-bound GTPases that are linked to 7-TM receptors. They function as signal transducer... | |||
TMPY-02805 | GNGT1 Protein, Human, Recombinant (His) | Human | E. coli |
GNGT1 is a subunit of transducin. Heterotrimeric G proteins consist of alpha, beta, and gamma subunits. They are membrane-bound GTPases that are linked to 7-TM receptors. They function as signal transducers for the 7-tra... | |||
TMPY-01888 | KRAS Protein,Human, Recombinant (Q61H, His) | Human | E. coli |
K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec... | |||
TMPY-06056 | KRAS Protein, Human, Recombinant (G12D, His) | Human | E. coli |
K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec... | |||
TMPY-04113 | KRAS Protein,Human,Recombinant(G12D & Q61H, His) | Human | E. coli |
K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec... | |||
TMPY-04116 | KRAS Protein,Human,Recombinant(G12C & Q61H, His) | Human | E. coli |
K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec... | |||
TMPY-04310 | Apolipoprotein A-IV/APOA4 Protein, Human, Recombinant (His) | Human | HEK293 |
Apolipoprotein is genetically associated with the risk of Alzheimer's disease (AD). The APOA1, APOC3, and APOA4 genes are closely linked and located on human chromosome 11. There was a decreased trend for levels of APOA1... | |||
TMPY-03855 | DNase I Protein, Human, Recombinant (His) | Human | HEK293 |
DNase1, also known as deoxyribonuclease I and DNL1, is a member of the DNase family. DNaseI is a nuclease that cleaves DNA preferentially at phosphodiester linkages adjacent to a pyrimidine nucleotide, yielding 5'-phos... | |||
TMPY-02575 | PPAR gamma/PPARG Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
Peroxisome proliferator-activated receptor gamma (PPARG), a nuclear hormone receptor, plays a critical role in the lipid and glucose homeostasis, adipocyte differentiation, as well as intracellular insulin-signaling even... | |||
TMPY-03072 | IFN-omega Protein, Human, Recombinant (His) | Human | HEK293 |
IFNs are a large family of proteins having antiviral, antiproliferative, and immunomodulatory effects, and are divided into two major classes, type I and type II, based on differences in receptor binding and nucleotide s... | |||
TMPY-02566 | Interferon alpha 4/IFNA4 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Interferon, alpha 4 (IFNA4) belongs to the alpha/beta interferon family. Two variants of IFNA4 (IFNA4a and IFNA4b) are known, which differ from each other by changes in their coding regions at nucleotide positions 220 an... | |||
TMPY-01186 | Argonaute-2 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Argonaute 2 (AGO2), also known as Eukaryotic translation initiation factor 2C2 (EIF2C2), belongs to the Argonaute family, AGO subfamily, which is a component of the RNA-induced silencing complex (RISC) and mediates small... | |||
TMPY-02130 | Argonaute-2 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus-Insect Cells |
Argonaute 2 (AGO2), also known as Eukaryotic translation initiation factor 2C2 (EIF2C2), belongs to the Argonaute family, AGO subfamily, which is a component of the RNA-induced silencing complex (RISC) and mediates small... | |||
TMPH-02280 | SNRNP70 Protein, Human, Recombinant (His) | Human | E. coli |
Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleoti... | |||
TMPH-02281 | UBALD2 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleoti... | |||
TMPH-01283 | EEF1A1 Protein, Human, Recombinant (His) | Human | E. coli |
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. | |||
TMPH-00931 | ANAPC15 Protein, Human, Recombinant (GST) | Human | E. coli |
Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase. | |||
TMPH-03503 | Adenylate kinase Protein, Shigella flexneri, Recombinant (His & Myc & SUMO) | Shigella flexneri | E. coli |
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. | |||
TMPH-03163 | SVTLE Protein, Protobothrops flavoviridis, Recombinant (His & Myc) | Protobothrops flavoviridis | E. coli |
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. | |||
TMPH-00057 | AsFP595 Protein, Anemonia sulcata, Recombinant (GST) | Anemonia sulcata | E. coli |
Data show that the total length of the aligned Yak cathelicidin 6 (CATHL-6) sequences was 1923 bp, including six single nucleotide polymorphisms and one indel. PMID: 25966077 Characterization of single nucleotide polymor... | |||
TMPY-01819 | PDE1B Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B, also known as Cam-PDE 1B and PDE1B, is a cytoplasm protein that belongs to the cyclic nucleotide phosphodiesterase family and PDE1 subfamily. Pho... | |||
TMPY-02880 | ENPP5 Protein, Human, Recombinant (His) | Human | HEK293 |
ENPP5 is a member of the nucleotide pyrophosphatase/phosphodiesterase family (NPP). It is a family comprised of dimeric enzymes that catalyze the hydrolysis of phosphate diester bonds. There are seven isoforms in NPP fam... | |||
TMPY-03849 | NUDT5 Protein, Human, Recombinant (His) | Human | E. coli |
NUDT5 (Nudix Hydrolase 5) is a Protein Coding gene. This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphos... | |||
TMPH-02666 | Fukutin Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. A... | |||
TMPJ-00792 | DNA PolymeraseBeta Protein, Human, Recombinant (His) | Human | E. coli |
Human DNA polymerase β is constitutively expressed in cells. It fills in gaps in DNA that are formed following base excision repair. Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-p... | |||
TMPH-02380 | RPB5 Protein, Kluyveromyces marxianus, Recombinant (His) | Kluyveromyces marxianus | E. coli |
Nuclease required for the repair of DNA interstrand cross-links (ICL) recruited at sites of DNA damage by monoubiquitinated FANCD2. Specifically involved in repair of ICL-induced DNA breaks by being required for efficien... | |||
TMPY-05055 | GGH/Glutamyl hydrolase gamma Protein, Human, Recombinant (His) | Human | HEK293 |
gamma-Glutamyl hydrolase (GGH) regulates intracellular folates and antifolates such as methotrexate (MTX) for proper nucleotide biosynthesis and antifolate-induced cytotoxicity, respectively. GGH is a ubiquitously-expres... | |||
TMPK-01247 | ITGB6 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
ITGB6 is known to be one of the major receptor components involved in host tropism of foot-and-mouth disease (FMD) virus in cattle. A competitive PCR technique called ARMS PCR was adapted to identify a single-nucleotide ... | |||
TMPK-00839 | ITGB6 Protein, Human, Recombinant (His) | Human | HEK293 |
ITGB6 is known to be one of the major receptor components involved in host tropism of foot-and-mouth disease (FMD) virus in cattle. A competitive PCR technique called ARMS PCR was adapted to identify a single-nucleotide ... | |||
TMPH-02543 | DEFB33 Protein, Mouse, Recombinant (His & Myc & SUMO) | Mouse | E. coli |
5'->3' DNA exonuclease which digests single-stranded DNA (ssDNA). Regulates inflammatory cytokine responses via the degradation of nucleic acids, by reducing the concentration of ssDNA able to stimulate TLR9, a nucleotid... | |||
TMPH-00792 | FtnA Protein, Helicobacter pylori, Recombinant (His) | Helicobacter pylori | Baculovirus |
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guan... | |||
TMPJ-01072 | GALK2 Protein, Human, Recombinant (His) | Human | Human Cells |
GALK2 acts as a galactokinase when galactose is present at high concentrations. GALK2 may be involved in a salvage pathway for the reutilization of free GalNAc derived from the degradation of complex carbohydrates. GALK2... | |||
TMPH-01282 | ELAVL4 Protein, Human, Recombinant (His & Myc & SUMO) | Human | E. coli |
Heterotrimeric guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide bi... | |||
TMPH-01936 | GPR107 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the T... | |||
TMPK-00964 | MAdCAM-1 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) contributes to the recruitment of donor T cells into the mucosal tissues of the recipient after allogeneic hematopoietic stem cell transplantation (aHSCT). The aim of... | |||
TMPY-06138 | KRAS Protein, Human, Recombinant (61Q, His) | Human | E. coli |
K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec... | |||
TMPK-00965 | MAdCAM-1 Protein, Human, Recombinant (aa 19-317, hFc) | Human | HEK293 |
Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) contributes to the recruitment of donor T cells into the mucosal tissues of the recipient after allogeneic hematopoietic stem cell transplantation (aHSCT). The aim of... | |||
TMPK-00966 | MAdCAM-1 Protein, Human, Recombinant (aa 19-317, His) | Human | HEK293 |
Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) contributes to the recruitment of donor T cells into the mucosal tissues of the recipient after allogeneic hematopoietic stem cell transplantation (aHSCT). The aim of... | |||
TMPK-01031 | MAdCAM-1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) contributes to the recruitment of donor T cells into the mucosal tissues of the recipient after allogeneic hematopoietic stem cell transplantation (aHSCT). The aim of... | |||
TMPH-02077 | Semaphorin-3G/SEMA3G Protein, Human, Recombinant (His & Myc) | Human | HEK293 |
Could be a guanine-nucleotide releasing factor. Plays a role in ciliogenesis. Probably regulates cilia formation by regulating actin stress filaments and cell contractility. Plays an important role in photoreceptor integ... | |||
TMPY-03617 | GMPR Protein, Human, Recombinant (His) | Human | E. coli |
GMPR, also known as GMPR1, belongs to the IMPDH/GMPR family.This familyofenzymesincludesIMP dehydrogenaseandGMP reductase. These enzymes are involved inpurine metabolism and adopt aTIM barrelstructure. GMPR is an enzyme ... | |||
TMPH-00703 | Pal Protein, E. coli, Recombinant (His & Myc) | E. coli | E. coli |
Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded pr... | |||
TMPH-01497 | HLA-DMA Protein, Human, Recombinant (His) | Human | E. coli |
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Sign... | |||
TMPY-02977 | PDE1C Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
PDE1C belongs to the cyclic nucleotide phosphodiesterase family, PDE1 subfamily. Phosphodiesterases (PDEs) are a family of related phosphohydrolyases that selectively catalyze the hydrolysis of 3' cyclic phosphate bonds ... | |||
TMPJ-00689 | EIF1B Protein, Human, Recombinant (His) | Human | E. coli |
Eukaryotic Translation Initiation Factor 1B (EIF1B) is an element of a complex involved in recognition of the initiator codon during the scanning process. Translation is also initiated by the function of EIF1B in regulat... | |||
TMPK-01268 | Complement C2 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Single nucleotide polymorphism (SNP) of complement component 2 (C2) has been found to be significantly associated with hepatocellular carcinoma (HCC). Significantly lower C2 expression was found at HCC compared to health... | |||
TMPJ-01450 | SARS-CoV-2 Helicase Protein (His & MBP) | SARS-CoV-2 | E. coli |
The non—structural protein 13 (nsp13) of SARS—CoV 2 is a helicase that separates double—stranded RNA or DNA with a 5'—3' polarity, using the energy of nucleotide hydrolysis. A basic biochemical characterization of nsp13 ... | |||
TMPJ-01262 | UPRT Protein, Human, Recombinant (His) | Human | E. coli |
UPRT is a cytoplasmic enzyme which belongs to the UPRTase family. UPRT is highly expressed in leukocytes, liver, spleen and thymus, with lower expression in brain, lung and skeletal muscle. UPRTcatalyzes the conversion o... | |||
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Cat No. | Product Name | ||
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L1720 | Nucleotide Compound Library | 337 compounds | |
A unique collection of 337 nucleoside and nucleotide analogues, can be used for research and development of anti-viral, anti-tumor, anti-fungal, and anti-depressive drugs; |