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Results for "

heart

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    513
    TargetMol | Inhibitors_Agonists
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    10
    TargetMol | Compound_Libraries
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    44
    TargetMol | Peptide_Products
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    TargetMol | Inhibitory_Antibodies
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    TargetMol | Inhibitors_Agonists
Captopril
SQ-14534, SQ 14225, SA333
T146262571-86-2
Captopril (SA333) is a potent and specific inhibitor of peptidyl-dipeptidase A. It blocks the conversion of angiotensin I to angiotensin II, a vasoconstrictor and important regulator of arterial blood pressure.
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Heptadecanoic acid
T4903506-12-7
Heptadecanoic acid is a fatty acid of exogenous (primarily ruminant) origin. Many odd length long chain amino acids are derived from the consumption of dairy fats (milk and meat). Heptadecanoic acid constitutes 0.61% of milk fat and 0.83% of ruminant me
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Deslanoside
Desacetyllanatoside C, Deacetyllanatoside C
T818317598-65-1
Deslanoside (Desacetyllanatoside C) is a rapidly acting cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias associated with reentry mechanisms. It inhibits the Na-K-ATPase membrane pump, increasing intracellular sodium and calcium concentrations.
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RO2959 Hydrochloride
RO2959 HCl
T88671219927-22-6
RO2959 Hydrochloride (RO2959 HCl) is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.
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Carvedilol
SKF 105517, BM 14190
T044772956-09-3
Carvedilol (SKF 105517) Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathomimetic activity. The S enantiomer of carvedilol nonselectively binds to and blocks beta-adrenergic receptors, thereby exerting negative inotropic and chronotropic effects, and leading to a reduction in cardiac output. In addition, both enantiomers of carvedilol bind to and block alpha 1-adrenergic receptors, thereby causing vasodilation and reducing peripheral vascular resistance.
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Anti-Heart Failure Agent 1
T10515142648-47-3
Anti-Heart Failure Agent 1 is an orally available compound suitable for treating heart failure without causing vomiting, nausea, or restlessness.
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6-8 weeks
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Cardiolipin (Heart, Bovine) sodium
T74031383907-10-6
Cardiolipin (Heart, Bovine) sodium is a phospholipid found in mitochondria and is involved in mitochondrial structure and function.Cardiolipin (Heart, Bovine) sodium is used in the study of neurological, cardiovascular, and metabolic diseases.
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7-10 days
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Heart-homing peptide
TP2778876460-72-9
Heart-homing peptide, abbreviated as CRPPR, is a linear peptide consisting of arginine-rich sequences. Identified as a cardiac-homing peptide due to its specific ability to bind to cardiac endothelium, CRPPR has been proposed to interact with Cysteine-rich intestinal protein-2 (CRIP-2) as its receptor. Additionally, this peptide is utilized for binding to liposomes.
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Heart-homing peptide TFA
TP3128
Heart-homing peptide TFA is a pentapeptide with the sequence CRPPR. This linear peptide contains arginine and has been identified as a heart-homing peptide due to its ability to specifically bind to cardiac endothelium. Cysteine-rich protein-2 (CRIP-2) has been proposed as its receptor. Heart-homing peptide TFA can be used for liposome binding.
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7-10 days
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Brain Heart Infusion Agar
TXB-00412
Brain Heart Infusion Agar is a medium used for cultivating a variety of microorganisms.
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Inquiry
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Brain Heart Infusion Broth
TXB-00537
Brain Heart Infusion Broth (BHI) is used for the cultivation of microorganisms, including Streptococcus, Pneumococcus, and Meningococcus.
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Beef Heart Infusion
TXB-00538
Beef Heart Infusion is a non-selective microbial culture medium that supplies essential nutrients for microorganism growth. It is suitable for the cultivation, subculturing, and revitalization of microorganisms.
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Candoxatril
UK 79300
T10671123122-55-4In house
Candoxatril (UK 79300) is an orally active neutral peptide endonuclease (NEP, EC 3.4.24.11) inhibitor that improves exercise capacity in patients with chronic heart failure undergoing angiotensin-converting enzyme inhibition.
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7-10 days
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TargetMol | Inhibitor Hot
Forskolin
FSK, Colforsin, Coleonol
T293966575-29-9
Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM). Forskolin increases cAMP levels, activates PXR and FXR, and induces autophagy. Forskolin produces positive inotropic effects in the heart, and has platelet anticoagulant and antihypertensive effects.
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TargetMol | Inhibitor Hot
TDI-011536
T601442687970-96-1
TDI-011536, a potent Lats kinase inhibitor, disrupts Hippo-Yap signaling and promotes the proliferation of lesioned heart muscle cells. This compound is valuable for research in organ conservation and regeneration.
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TargetMol | Inhibitor Hot
Mitiperstat
AZD4831
T610281933460-19-5
Mitiperstat is a potent myeloperoxidase (MPO) inhibitor that is effective in preventing cardiovascular diseases such as heart failure and coronary artery disease.
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8-10 weeks
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TargetMol | Inhibitor Hot
AZD5462
T638382787501-83-9
AZD5462 is a potent orally available relaxin receptor RXFP1 agonist for the study of heart failure and cancer.
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10-14 weeks
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TargetMol | Inhibitor Hot
Arbutamine
GP 21213
T10364128470-16-6In house
Arbutamine (GP 21213) is a novel potent non-selective beta-adrenoceptor agonist with alpha-1-sympathomimetic activity.Arbutamine promotes cardiac stress and increases heart rate, cardiac contractility.Arbutamine can be used to study cardiac stress and coronary artery disease
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6-8 weeks
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Bucindolol Formate
Bucindolol Formate (71119-11-4 Free base)
T10631L In house
Bucindolol Formatel is a blocker of β1-adrenergic receptor. Bucindolol exhibits intrinsic sympathomimetic activity. Bucindolol can be used in the research of heart failure.
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Cicloprolol hydrochloride
T1081263686-79-3In house
Cicloprolol hydrochloride is a new potent and selective beta 1-adrenoceptor antagonist with partial agonist activity for the study of coronary heart disease.
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6-8 weeks
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Drobuline hydrochloride
T1109768162-52-7In house
Drobuline hydrochloride, an anti-arrhythmic agent with cardiac depressant activity, is used to manage abnormal heart rhythms.
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6-8 weeks
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OR-1896
T12315220246-81-1In house
OR-1896 is the active metabolite of Levosimendan, a highly specific phosphodiesterase (PDE III) inhibitor, a vasodilator with partial anti-inflammatory properties that produces vasodilation in different types of blood vessels through activation of ATP-sensitive (KATP) and other potassium channels.OR-1896 can be used to study heart failure and vascular dysfunction. OR-1896 can be used to study heart failure and vascular dysfunction.
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6-8 weeks
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(2R,3S)-Azelaprag
T14390L2049979-31-7In house
(2R,3S)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methylpyridin-3-yl)-4H-1,2,4-triazol-3-yl)-3-(5-methylpyrimidin-2-yl)butane-2-sulfonamide is an Apelin receptor agonist with an EC50 for Apelin receptors of 0.012 µM.(2R,3S)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methylpyridin-3-yl)-4H-1,2,4-triazol-3-yl)-3-(5- methylpyrimidin-2-yl)butane-2-sulfonamide is used in the treatment of heart failure, atherosclerosis, obesity, diabetes mellitus, amyotrophic lateral sclerosis, coronary artery disease, hypertension, stroke and myocardial infarction.
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10-14 weeks
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PD-118057
T16444313674-97-4In house
PD-118057 is a potent ether associated (hERG) potassium channel activator that shows no activity against hERG. PD-118057 inhibits the excitability of the membrane by activating the hERG channel. PD-118057 is a potential compound for the treatment of delayed repolarization in inherited or acquired long QT syndrome and congestive heart failure.
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6-8weeks
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