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Results for "

heart

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    535
    TargetMol | Inhibitors_Agonists
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    10
    TargetMol | Compound_Libraries
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    44
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    TargetMol | Inhibitors_Agonists
Nicorandil
SG-75
T007565141-46-0
Nicorandil (SG-75)(Ikorel) acts by relaxing the smooth muscle of the blood vessels, especially those of the venous system. It undertakes this through two methods. Firstly, by activating potassium channels, and secondly by donating nitric oxide to activate the enzyme guanylate cyclase. Guanylate cyclase causes activation of cGMP leading to both arterial and venous vasodilatation by de-phosphorylation of the myosin light chain.
  • $35
In Stock
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Phentolamine mesylate
Phentolamine methanesulfonate, Phentolamine mesilate
T127565-28-1
Phentolamine mesylate (Phentolamine methanesulfonate) is a nonselective alpha-adrenergic antagonist used to treat hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of [RAYNAUD DISEASE] and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
  • $51
In Stock
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Torsemide
Torasemide, JDL-464, AC-4464
T141056211-40-6
Torsemide (AC-4464) is an anilinopyridine sulfonylurea belonging to the class of loop diuretics. Torsemide has a prolonged duration of action compared to other loop diuretics, is extensively protein bound in plasma and has a relatively long half-life.
  • $30
In Stock
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Captopril
SQ-14534, SQ 14225, SA333
T146262571-86-2
Captopril (SA333) is a potent and specific inhibitor of peptidyl-dipeptidase A. It blocks the conversion of angiotensin I to angiotensin II, a vasoconstrictor and important regulator of arterial blood pressure.
  • $40
In Stock
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Heptadecanoic acid
T4903506-12-7
Heptadecanoic acid is a fatty acid of exogenous (primarily ruminant) origin. Many odd length long chain amino acids are derived from the consumption of dairy fats (milk and meat). Heptadecanoic acid constitutes 0.61% of milk fat and 0.83% of ruminant me
  • $31
In Stock
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Isosorbide
Isobide, Hydronol, D-Isosorbide, Dianhydro-D-glucitol, Devicoran
T6551652-67-5
Isosorbide (Devicoran) is a heterocyclic compound that is derived from glucose, used as a diuretic.
  • $40
In Stock
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Nitroprusside disodium dihydrate
Sodium Nitroprusside Dihydrate, Sodium Nitroferricyanide(III) Dihydrate
T699113755-38-9
Nitroprusside disodium dihydrate (Sodium Nitroprusside Dihydrate) is a potent vasodilator working through releasing NO spontaneously in blood.
  • $44
In Stock
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Carvedilol
SKF 105517, BM 14190
T044772956-09-3
Carvedilol (SKF 105517) Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathomimetic activity. The S enantiomer of carvedilol nonselectively binds to and blocks beta-adrenergic receptors, thereby exerting negative inotropic and chronotropic effects, and leading to a reduction in cardiac output. In addition, both enantiomers of carvedilol bind to and block alpha 1-adrenergic receptors, thereby causing vasodilation and reducing peripheral vascular resistance.
  • $35
Backorder
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BMS-986235
LAR-1219, BMS-986235
T397892253947-47-4
BMS-986235 (LAR-1219) is a selective and orally active agonist of formyl peptide receptor 2 (FPR2) with EC50s of 0.41 nM for hFPR2 and 3.4 nM for mFPR2. BMS-986235 can be used in studies on the prevention of heart failure.
  • $64
In Stock
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Olprinone
Loprinone
T5033106730-54-5
Olprinone (Loprinone)(Loprinone) is a selective phosphodiesterase 3 (PDE3) inhibitor.Olprinone has been reported to improve microcirculation and attenuate inflammation. Olprinone is often used to increase cardiac output after cardiopulmonary bypass (CPB).
  • $30
In Stock
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Deslanoside
Desacetyllanatoside C, Deacetyllanatoside C
T818317598-65-1
Deslanoside (Desacetyllanatoside C) is a rapidly acting cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias associated with reentry mechanisms. It inhibits the Na-K-ATPase membrane pump, increasing intracellular sodium and calcium concentrations.
  • $77
In Stock
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RO2959 Hydrochloride
RO2959 HCl
T88671219927-22-6
RO2959 Hydrochloride (RO2959 HCl) is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.
  • $79
In Stock
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Anti-Heart Failure Agent 1
T10515142648-47-3
Anti-Heart Failure Agent 1 is an orally available compound suitable for treating heart failure without causing vomiting, nausea, or restlessness.
  • $1,520
6-8 weeks
Size
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Cardiolipin (Heart, Bovine) sodium
T74031383907-10-6
Cardiolipin (Heart, Bovine) sodium is a phospholipid found in mitochondria and is involved in mitochondrial structure and function.Cardiolipin (Heart, Bovine) sodium is used in the study of neurological, cardiovascular, and metabolic diseases.
  • $30
In Stock
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Heart-homing peptide
TP2778876460-72-9
Heart-homing peptide, abbreviated as CRPPR, is a linear peptide consisting of arginine-rich sequences. Identified as a cardiac-homing peptide due to its specific ability to bind to cardiac endothelium, CRPPR has been proposed to interact with Cysteine-rich intestinal protein-2 (CRIP-2) as its receptor. Additionally, this peptide is utilized for binding to liposomes.
  • Inquiry Price
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Heart-homing peptide TFA
TP3128
Heart-homing peptide TFA is a pentapeptide with the sequence CRPPR. This linear peptide contains arginine and has been identified as a heart-homing peptide due to its ability to specifically bind to cardiac endothelium. Cysteine-rich protein-2 (CRIP-2) has been proposed as its receptor. Heart-homing peptide TFA can be used for liposome binding.
  • $36
7-10 days
Size
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Brain Heart Infusion Agar
TXB-00412
Brain Heart Infusion Agar is a medium used for cultivating a variety of microorganisms.
  • Inquiry Price
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Brain Heart Infusion Broth
Brain Heart Infusion Broth, BHI
TXB-00537
Brain Heart Infusion Broth (BHI) is used for the cultivation of microorganisms, including Streptococcus, Pneumococcus, and Meningococcus.
  • Inquiry Price
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Beef Heart Infusion
TXB-00538
Beef Heart Infusion is a non-selective microbial culture medium that supplies essential nutrients for microorganism growth. It is suitable for the cultivation, subculturing, and revitalization of microorganisms.
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Doxorubicin hydrochloride
NSC 123127, Hydroxydaunorubicin hydrochloride, DOX hydrochloride, Adriamycin HCl
T102025316-40-9
Doxorubicin hydrochloride is an anthracycline antibiotic with cytotoxic and antitumor activity. It is an effective inhibitor of human DNA topoisomerase I and II, with IC50 values of 0.8 μM and 2.67 μM, respectively. In addition to inhibiting DNA topoisomerases, it can reduce the phosphorylation of AMPK and its downstream target, acetyl-CoA carboxylase. Doxorubicin hydrochloride also induces apoptosis and autophagy. In animal studies, it is commonly used to induce models of acute renal failure, chronic kidney injury, and heart failure.
  • $34
In Stock
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TargetMol | Inhibitor Hot
Candoxatril
UK 79300
T10671123122-55-4In house
Candoxatril (UK 79300) is an orally active neutral peptide endonuclease (NEP, EC 3.4.24.11) inhibitor that improves exercise capacity in patients with chronic heart failure undergoing angiotensin-converting enzyme inhibition.
  • $293
In Stock
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TargetMol | Inhibitor Hot
Forskolin
FSK, Colforsin, Coleonol
T293966575-29-9
Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM). Forskolin increases cAMP levels, activates PXR and FXR, and induces autophagy. Forskolin produces positive inotropic effects in the heart, and has platelet anticoagulant and antihypertensive effects.
  • $36
In Stock
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TargetMol | Inhibitor Hot
TDI-011536
T601442687970-96-1
TDI-011536, a potent Lats kinase inhibitor, disrupts Hippo-Yap signaling and promotes the proliferation of lesioned heart muscle cells. This compound is valuable for research in organ conservation and regeneration.
  • $51
In Stock
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TargetMol | Inhibitor Hot
AZD5462
T638382787501-83-9
AZD5462 is a potent orally available relaxin receptor RXFP1 agonist for the study of heart failure and cancer.
  • $373
In Stock
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TargetMol | Inhibitor Hot