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Cat No. | Product Name | Synonyms | Targets |
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T3593 | Src Inhibitor 1 | Src Kinase Inhibitor 1,Src-l1 | Src |
Src Inhibitor 1 (Src Kinase Inhibitor 1) is a potent and selective dual site Src tyrosine kinase inhibitor. | |||
TP2289L | RR-src acetate | RR-src acetate(81156-93-6 Free base) | Others |
RR-src acetate is a synthetic peptide derived from the amino acid sequence surrounding the phosphorylation site in pp60src. | |||
T13000 | Src Inhibitor 3 | Others , Src | |
Src Inhibitor 3 is an effective inhibitor of c-terminal Src kinase (IC50 <3 nM in CSK HTRF, <4 nM in Caliper assay). Src Inhibitor 3 increases T cell proliferation induced by T cell receptor signaling. | |||
TP2137L | Pp60 c-src (521-533) (phosphorylated) acetate | Others | |
pp60 c-src (521-533) (phosphorylated) acetate is a regulator of focal adhesion formation and cell spreading. pp60 c-src (521-533) (phosphorylated) acetate also regulates cell motility and is a key component in the signal... | |||
T39185 | Pp60 (v-SRC) Autophosphorylation Site, Phosphorylated | pp60 (v-SRC) Autophosphorylation Site, Phosphorylated | |
pp60 (v-SRC) Autophosphorylation Site, Phosphorylated is a phosphorylated peptide derived from an EGFR substrate. It serves as a valuable tool for quantifying phosphorylated substrates in screening EGFR Kinase inhibitors... | |||
T11745 | KB SRC 4 | Src | |
KB SRC 4 is a selective and potent c-Src inhibitor with antitumour activity that inhibits the growth of cancer cells. | |||
T39149 | Src Optimal Peptide Substrate | ||
Src Optimal Peptide Substrate, a highly specific substrate of Src, serves as a reliable indicator of Src activity. It enables accurate assessment of Src kinase function. | |||
TP2289 | RR-src | Others | |
Tyrosine kinase substrate peptide | |||
T1811 | WH-4-023 | KIN112,KIN001-112,Dual LCK/SRC inhibitor | Src |
WH-4-023 (Dual LCK/SRC inhibitor) is a potent and orally active Lck/Src inhibitor. It also potently inhibits SIK. | |||
T13062 | T338C Src-IN-2 | Others | |
T338C Src-IN-2 is a potent mutant inhibitor of c-Src T338C kinase(IC50 of 317 nM). T338C Src-IN-2 also inhibits T338C/V323A and T338C/V323S(IC50 of 57 nM/19 nM,respectively). | |||
T13061 | T338C Src-IN-1 | Others | |
T338C Src-IN-1 is a potent mutant-Src T338C inhibitor(T338C,IC50=111 nM relative to WT c-Src (10-fold increase)). | |||
TP2137 | Pp60 c-src (521-533) (phosphorylated) | ||
Peptide corresponding to the pp60c-src carboxy terminal regulatory domain; phosphorylated at Tyr527. Binds to pp60c-src and pp60v-src at the SH2 domain, suppressing their tyrosine kinase activity and transforming potenti... | |||
T76391 | P60c-src substrate II | ||
p60c-src substrate II is an efficient pentapeptide substrate for the tyrosine kinase pp60c-src [1] . | |||
T81577 | P60v-src(137-157) | ||
P60v-src(137-157) is a synthetic peptide that serves as an inhibitor of the tyrosine kinase activity of p60 v-src, with an IC50 value of 7.5 μM [1] [2]. | |||
T81106 | SRC-1 (686-700) | ||
SRC-1 (686-700) is a bioactive peptide encompassing amino acids 686 to 700, which include the second LXXLL motif from NR box II of steroid receptor coactivator (SRC1). These coactivator proteins facilitate transcription ... | |||
T81578 | P60c-src substrate II, phosphorylated | ||
Phosphorylated p60c-src substrate II is a pentapeptide and a phosphorylated polypeptide form of p60c-src substrate II. Phosphorylation is a critical post-translational modification (post-translationmodification) vital fo... | |||
T83752 | Biotin-SRC-1 (676–700) TFA | Biotin-Steroid Receptor Coactivator 1 (676-700) | |
Biotin-SRC-1 (676–700), a biotinylated and truncated variant of steroid receptor coactivator 1 (SRC-1), finds application in affinity-based reporter assays such as time-resolved FRET (TR-FRET) and amplified luminescent p... | |||
T0152 | Bosutinib | SKI-606 | Bcr-Abl , Src , Autophagy |
Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50: 1 nM) and Src (IC50: 1.2 nM) kinases. | |||
T8499 | ECF506 | Src | |
eCF506 is a potent and selective inhibitor of SRC (IC50 < 0.5 nM) | |||
T17267 | XL228 | IGF-1R , Bcr-Abl , Src , Aurora Kinase | |
XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively). | |||
T3063 | PD173955 | PD-173955,PD 173955 | Apoptosis , Bcr-Abl , Src |
PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes and Abl kinase; less potent for FGFRα and no activity on InsR and PKC. | |||
T6078 | Saracatinib | AZD0530 | EGFR , Src , BTK , Autophagy |
Saracatinib (AZD0530) (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes. | |||
T13186 | TL02-59 | Apoptosis , Src , Hck | |
TL02-59 is a selective inhibitor of Fgr in Src-family kinase (IC50 = 0.03 nM). TL02-59 inhibits Lyn and Hck with IC50s of 0.1 nM and 160 nM, respectively. TL02-59 potently suppresses acute myelogenous leukemia cell growt... | |||
T4301 | AD80 | Raf , c-RET , Src , S6 Kinase | |
AD80, a multikinase inhibitor, inhibits RET, RAF, SRCand S6K, with greatly reduced mTOR activity. | |||
T4470 | Pyridostatin TFA | DNA/RNA Synthesis | |
Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-kit, K-ras and Bcl-2. | |||
T6594 | MNS | Syk , Src , p97 | |
MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively. | |||
T11538 | Hck-IN-1 | HIV Protease , Src , Hck | |
Hck-IN-1 is a selective Nef-dependent Hck inhibitor (IC50s: 2.8 μM and >20 μM for Nef:Hck complex and Hck) with antiretroviral activity. Hck-IN-1 is a direct and wide HIV-1 Nef antagonist with an IC50 of 100-300 nM for w... | |||
T6345 | Tirbanibulin | KX2-391,KX-01 | Microtubule Associated , Src |
Tirbanibulin (KX2-391) is a highly selective Src kinase inhibitor that has demonstrated efficacy in pre-Clinicalal animal models of colon, pancreatic, prostate and breast cancer. It is a substrate-targeted kinase inhibit... | |||
T4597 | UM-164 | UM164,DAS-DFGO-II | p38 MAPK , Src , Autophagy |
UM-164 (DAS-DFGO-II) is a highly potent inhibitor of c-Src with a Kd of 2.7 nM. UM-164 also potently inhibits p38α and p38β. | |||
T2153 | 1-NM-PP1 | PP1 Analog II,1 nM-PP1 | Serine/threonin kinase , CDK , Src |
1-NM-PP1 (PP1 Analog II) is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors. | |||
T6997 | SU6656 | FAK , Akt , Src | |
SU 6656 is a selective inhibitor of Src family kinases, with IC50 of 280 nM, 20 nM, 130 nM, and 170 nM for Src, Yes, Lyn, and Fyn, respectively. | |||
T1812 | KX1-004 | KX1 004,KX1004 | Src |
KX1-004, a potential protective drug for NIHL, is an effective small molecule inhibitor of Src-PTK. | |||
T13194 | CSF1R-IN-2 | c-Fms , c-Met/HGFR , Src | |
CSF1R-IN-2 is an oral-active SRC, MET and c-FMS inhibitor (IC50s: 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively). | |||
T2415 | PP121 | Apoptosis , VEGFR , Bcr-Abl , PDGFR , Src , mTOR , Hck | |
PP-121 is a multi-targeted inhibitor of PDGFR (IC50: 2 nM), Hck (IC50: 8 nM), mTOR (IC50: 10 nM), VEGFR2(IC50: 12 nM), Src (IC50: 14 nM) and Abl (IC50: 18 nM) , also inhibits DNA-PK (IC50: 60 nM). | |||
T7123 | AMG-47a | VEGFR , p38 MAPK , JAK , Src | |
AMG-47a is a potent inhibitor of Lck and T cell proliferation. AMG-47a could promote the degradation of the KRAS oncoprotein. AMG-47a selectively reduced the levels of EGFP-KRASG12V protein but did not affect EGFP protei... | |||
T2640 | Rebastinib | DCC2036,DCC 2036,DCC-2036 | Apoptosis , FLT , Bcr-Abl , Src |
DCC-2036 (Rebastinib (DCC-2036)) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50: 0.8 nM) and Abl1(T315I, IC50: 4 nM), also inhibits LYN, SRC, HCK, FGR, FLT3, KDR, and Tie-2, and low activity to c-Kit. Re... | |||
T1448 | Dasatinib | BMS-354825 | Apoptosis , Bcr-Abl , Src , c-Kit , Autophagy |
Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive. Dasatinib has antitumor activity and is used in the treatment of leukemia and ly... | |||
T6196 | PP1 | EI 275,AGL 1872 | Apoptosis , EGFR , Bcr-Abl , Src , c-Kit |
PP1 (AGL 1872), a specific and effective Src inhibitor, is with IC50 for Lck/Fyn is 5 nM/ 6 nM, respectively. | |||
T15675 | Tirbanibulin Mesylate | KX2-391 Mesylate,KX01 Mesylate | Microtubule Associated , Src |
Tirbanibulin Mesylate (KX01 Mesylate) is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines). | |||
TQ0132 | A 419259 trihydrochloride | RK 20449 trihydrochloride | Src |
A 419259 trihydrochloride (RK 20449 trihydrochloride) is an Src family kinases inhibitor (IC50s: 9 nM, 3 nM and 3 nM for Src, Lck and Lyn). | |||
T8719 | SC99 | Apoptosis , JAK , STAT | |
SC99 is a selective inhibitor of JAK2-STAT3 activation. SC99 downregulates the expression of STAT3-modulated genes.SC99 inhibits platelet activation, aggregation and displays potent anti-myeloma, anti-thrombotic activiti... | |||
T6896 | Tolimidone | NSC 314335,MLR-1023,CP-26154 | Src |
Tolimidone (NSC 314335) is a chemical compound which inhibits acid secretion in animal models and also acts as a bronchodilator in histamine-challenged animals. | |||
T3935 | 1-Naphthyl PP1 | 1-NA-PP 1 | Src |
1-Naphthyl PP1 (1-NA-PP 1) is a selective src inhibitor(v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively) | |||
T11826 | LCH-7749944 | GNF-PF-2356 | Apoptosis , PAK |
LCH-7749944 (GNF-PF-2356) effectively suppresses the proliferation of human gastric cancer cells through downregulation of PAK4/c-Src/EGFR/cyclin D1 pathway and induces apoptosis. LCH-7749944 is a potent PAK4 inhibitor w... | |||
T6311 | Bafetinib | NS-187,INNO-406 | Bcr-Abl , Src , Autophagy |
Bafetinib (INNO-406) (INNO-406) is an effective and specific dual Bcr-Abl/Lyn inhibitor (IC50: 5.8/19 nM), and no inhibition of the phosphorylation of the T315I mutant and less effective to c-Kit and PDGFR. | |||
T8976 | PD-089828 | EGFR , FGFR , PDGFR , Src | |
PD 089828 is a competitive inhibitor of the receptor tyrosine kinases FGFR1, PDGFRβ, and EGFR (IC50s = 0.15, 1.76, and 5.47 µM, respectively) and a noncompetitive inhibitor of the nonreceptor tyrosine kinase c-Src (IC50 ... | |||
T2358 | ENMD-2076 | Apoptosis , VEGFR , FGFR , FLT , c-RET , PDGFR , Src , Aurora Kinase | |
ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα. | |||
T2327 | Pelitinib | EKB-569,WAY-EKB 569 | EGFR , Raf , MEK , Src |
Pelitinib (EKB-569) (EKB-569) is an effective irreversible EGFR inhibitor (IC50: 38.5 nM). | |||
T0948 | Adrenalone hydrochloride | Adrenalone HCl | Adrenergic Receptor |
Adrenalone hydrochloride (Adrenalone HCl) is a dopamine β-oxidase inhibitor with a similar structure to the norepinephrine transporter (NET) ligand, with an IC50 of 36.9 μM. It is an adrenergic agonist that acts as a loc... | |||
T6266 | PP2 | AGL 1879,AG 1879,AGL 1879 | EGFR , Tyrosine Kinases , JAK , Src |
PP2 (AG 1879,AGL 1879) is a effective inhibitor of Lck/Fyn (IC50:4/5 nM) , ~100-fold less potent to EGFR, inactive for ZAP-70, PKA and JAK2. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5S1982 | Periplocin | Periplocoside | Apoptosis , Others |
1. Periplocin (Periplocoside) has anti-cancer effects on lung cancer cells, induces apoptosis and inhibits growth of cancer cells by the beta-catenin/Tcf signaling pathway. 2. Periplocin is used for treatment of rheumato... | |||
TN1440 | Beta-Hydroxyisovalerylshikonin | EGFR , Tyrosine Kinases , Prostaglandin Receptor , Src , AMPK , Fatty Acid Synthase | |
Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumor cell lines. Beta-Hydroxyisovalerylshikonin significantly de... | |||
TN2269 | Tetramethylcurcumin | Apoptosis , STAT | |
Tetramethylcurcumin is a novel curcumin analog, is an effective inhibitors of STAT3 phosphorylation, DNA binding activity, and transactivation in vitro.it also inhibits colony formation in soft agar, cell invasion, and e... | |||
T3319 | Scutellarein | 4',5,6,7-Tetrahydroxyflavone,6-Hydroxyapigenin | SARS-CoV , Src , Autophagy |
Scutellarein (6-Hydroxyapigenin) reduces inflammatory responses by inhibiting Src kinase activity. | |||
T7345 | 7-Hydroxy-4H-chromen-4-one | 7-hydroxy-4-benzopyrone,7-Hydroxy-4-chromone,7-Hydroxychromone | Src |
7-Hydroxy-4H-chromen-4-one (7-hydroxy-4-benzopyrone) is a Src kinase inhibitor (IC50 of <300 μM). | |||
TN1892 | Lusianthridin | Others , c-Myc | |
Lusianthridin is a natural product from Dendrobium venustum. Lusianthridin exhibits anti-migratory property at nontoxic concentrations. Lusianthridin enhances c-Myc degradation through the inhibition of Src-STAT3 signali... | |||
TQ0169 | Inulicin | 1-O-Acetylbritannilactone | FAK , NF-κB , COX , Src |
Inulicin (1-O-Acetylbritannilactone), an active compound isolated from Inula Britannica L, inhibits VEGF-mediated activation of Src and FAK. | |||
T3S2390 | Caftaric acid | trans-Caftaric acid | Others |
Caftaric acid (trans-Caftaric acid) is a natural product with antioxidant and anti-inflammatory properties, antimutagenicity, and an inhibitor of protein-protein interactions mediated by Src family kinases. | |||
TN1244 | 3'-Demethylnobiletin | LDL , NF-κB , Integrin , Lipoxygenase , DNA/RNA Synthesis | |
3'-Demethylnobiletin has chemopreventive effects on colon carcinogenesis, it can significantly inhibit the growth of human colon cancer cells, cause cell-cycle arrest, induce apoptosis, and profoundly modulate signaling ... | |||
T5S0761 | Nitidine chloride | Apoptosis , ERK , FAK , p38 MAPK , NF-κB , Topoisomerase , STAT , Parasite | |
1. Nitidine chloride has inhibitory effects on various tumors, such as renal cancer , breast cancer. 2. Nitidine chloride inhibits the proliferation of SMMC-7721 cells in vitro in a time- and dose-dependent manner and id... | |||
T6427 | Butein | 2’,3,4,4’-tetrahydroxy Chalcone | Apoptosis , EGFR , Others , PDE , Autophagy |
Butein (2’,3,4,4’-tetrahydroxy Chalcone), a plant polyphenol, is isolated from Rhus verniciflua. It can inhibit the activation of protein tyrosine kinase, NF-κB and STAT3, and also can inhibit EGFR. | |||
TN1143 | 1-O-Acetyl britannilactone | NF-κB , COX | |
1-O-Acetyl britannilactone shows antifungal, and anti-cancer activities, it suppresses angiogenesis and lung cancer cell growth possibly via regulating the VEGFR-Src-FAK signaling. | |||
T14055 | 5Z-7-Oxozeaenol | FR148083,L783279,LL-Z 1640-2 | VEGFR , FLT , MEK , MAPK , PDGFR , Antibiotic , Src |
5Z-7-Oxozeaenol (FR148083) is a potent, irreversible and selective inhibitor of transforming growth factor (TGF)-β-activated kinase 1 with IC50 of 8.1 nM for TAK1 and low activity against MEK1 with IC50 of 411 nM, it is ... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04384 | Src Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
Proto-oncogene tyrosine-protein kinase SRC is a hydrophobic protein belonging to the SRC family kinase including nine members that is a family of non-receptor tyrosine kinases. SRC protein may exist in different forms: C... | |||
TMPY-04434 | Src Protein, Mouse, Recombinant (His & GST) | Mouse | Baculovirus-Insect Cells |
Proto-oncogene tyrosine-protein kinase SRC is a hydrophobic protein belonging to the SRC family kinase including nine members that is a family of non-receptor tyrosine kinases. SRC protein may exist in different forms: C... | |||
TMPH-01977 | Src Protein, Human, Recombinant (His) | Human | E. coli |
May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated ... | |||
TMPY-04383 | CSK Protein, Human, Recombinant (GST) | Human | Baculovirus-Insect Cells |
The tyrosine kinase c-Src has been implicated as a modulator of cell proliferation, spreading, and migration. These functions are also regulated by Met. The structure of a large fragment of the c-Src kinase comprises the... | |||
TMPY-04444 | CSK Protein, Mouse, Recombinant (His & GST) | Mouse | Baculovirus-Insect Cells |
The tyrosine kinase c-Src has been implicated as a modulator of cell proliferation, spreading, and migration. These functions are also regulated by Met. The structure of a large fragment of the c-Src kinase comprises the... | |||
TMPY-04760 | CSK Protein, Mouse, Recombinant | Mouse | Baculovirus-Insect Cells |
The tyrosine kinase c-Src has been implicated as a modulator of cell proliferation, spreading, and migration. These functions are also regulated by Met. The structure of a large fragment of the c-Src kinase comprises the... | |||
TMPY-04388 | BLK Protein, Human, Recombinant (GST) | Human | Baculovirus-Insect Cells |
Tyrosine-protein kinase Blk, also known as B lymphocyte kinase, p55-Blk and BLK, is a member of theprotein kinase superfamily, Tyr protein kinase family and SRC subfamily. BLK / p55-Blk is expressed in lymphatic organ... | |||
TMPY-04391 | Lyn Protein, Human, Recombinant (GST) | Human | Baculovirus-Insect Cells |
Tyrosine-protein kinase Lyn is a member of the Src family of protein tyrosine kinases, which is mainly expressed in hematopoietic cells, in neural tissues liver, and adipose tissue. Tyrosine-protein kinase Lyn has many f... | |||
TMPY-04411 | YES1 Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
Proto-oncogene tyrosine-protein kinase Yes, also known as Proto-oncogene c-Yes, p61-Yes and YES1, is a cytoplasm protein that belongs to the protein kinase superfamily, Tyr protein kinase family and SRC subfamily. YES1 /... | |||
TMPJ-00778 | HER2/ERBB2 Protein, Human, Recombinant (His) | Human | Human Cells |
Human epidermal growth factor receptor 2 (HER2) is a type of membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 plays a key role in development, cell proliferation and different... | |||
TMPY-03835 | CDCP1 Protein, Rhesus, Recombinant (His) | Rhesus | HEK293 |
CDCP1 contains three extracellular CUB domains. It is a putative stem cell marker that is highly expressed in some human cancer cells and both, typical and atypical (cancerous) colons. It interacts with CDH2/N-cadherin, ... | |||
TMPY-04298 | CDCP1 Protein, Human, Recombinant (His) | Human | HEK293 |
CDCP1 contains three extracellular CUB domains. It is a putative stem cell marker that is highly expressed in some human cancer cells and both, typical and atypical (cancerous) colons. It interacts with CDH2/N-cadherin, ... | |||
TMPY-05308 | CD45 Protein, Human, Recombinant (aa 1-529, His) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-05748 | CD45 Protein, Human, Recombinant (aa 26-577, His) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-02005 | Mucin-1/MUC1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Mucin 1, cell surface-associated (MUC1) or polymorphic epithelial mucin (PEM) is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming pr... | |||
TMPY-05201 | Siglec-2/CD22 Protein, Human, Recombinant | Human | HEK293 |
CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. CD22 serves as an adhesi... | |||
TMPY-04083 | Siglec-2/CD22 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. CD22 serves as an adhesi... | |||
TMPY-05566 | Siglec-2/CD22 Protein, Human, Recombinant (His, Solution) | Human | HEK293 |
CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. CD22 serves as an adhesi... | |||
TMPY-02034 | Siglec-2/CD22 Protein, Human, Recombinant (His) | Human | HEK293 |
CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. CD22 serves as an adhesi... | |||
TMPY-04340 | Mucin-1/MUC1 Protein, Human, Recombinant | Human | HEK293 |
Mucin 1, cell surface-associated (MUC1) or polymorphic epithelial mucin (PEM) is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming pr... | |||
TMPH-02043 | RHOD Protein, Human, Recombinant (His & Myc) | Human | E. coli |
May regulate the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors. | |||
TMPY-02511 | PTP alpha/PTPRA Protein, Human, Recombinant (aa 174-793, His & GST) | Human | Baculovirus-Insect Cells |
PTPRA is reported to be involved in cancer development and progression through activating the Src family kinase (SFK) signaling pathways. The higher PTPRA level was associated with worse prognosis of SCC patients and PTP... | |||
TMPJ-00712 | MPZL1 Protein, Human, Recombinant (His) | Human | Human Cells |
Myelin protein zero-like protein 1(MPZL1) is encoded by the MPZL1 gene, which is a single-pass type I membrane protein. It is widely expressed with highest levels in heart, placenta, kidney and pancreas. As cell surface ... | |||
TMPJ-00184 | CD20 Protein, Human, Recombinant (Flag) | Human | Human Cells |
CD20 is a 33-37 kDa non-glycosylated protein expressed on the surface of normal and malignant B lymphocytes, and belongs to the MS4A (membrane-spanning 4-domain family A) protein family. CD20 protein consists of four hyd... | |||
TMPH-00926 | MAOB Protein, Human, Recombinant (His) | Human | E. coli |
Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including neurogenesis, vascular development, angiogenesis and osteogenesis. Acts in concert with PTHLH/PTHRP to stimu... | |||
TMPH-01288 | Elongin-B Protein, Human, Recombinant (GST) | Human | E. coli |
Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to ... | |||
TMPK-00423 | CD45 Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) com... | |||
TMPJ-00185 | CD20 Protein, Human, Recombinant (His & Flag) | Human | Human Cells |
CD20 is a 33-37 kDa non-glycosylated protein expressed on the surface of normal and malignant B lymphocytes, and belongs to the MS4A (membrane-spanning 4-domain family A) protein family. CD20 protein consists of four hyd... | |||
TMPY-02761 | Rack1 Protein, Human, Recombinant (His & MBP) | Human | E. coli |
The scaffolding protein, Rack1, is a seven-WD-domain-containing protein that has been implicated in binding to integrin beta subunit cytoplasmic domains and to members of two kinase families (src and protein kinase C, PK... | |||
TMPK-00457 | HGFR/c-Met Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene.The protein possesses tyrosine kinase activity. The primary single chain ... | |||
TMPK-00447 | CD45 Protein, Human, Recombinant (aa 26-577, hFc) | Human | HEK293 |
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) com... | |||
TMPK-00424 | CD45 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) com... | |||
TMPY-03510 | Cbl-c Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
CBL proteins, such as Cbl-c, are phosphorylated upon activation of a variety of receptors that signal via protein tyrosine kinases. Through interactions with proteins containing SRC homology-2 (SH2) and SH3 domains, C... | |||
TMPK-00499 | HGFR/c-Met Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene.The protein possesses tyrosine kinase activity. The primary single chain ... | |||
TMPY-03824 | CD43 Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
CD43 is an abundantly expressed molecule on the T-cell surface that shows distinct localization to the migrating T-cell uropod and the distal pole complex (DPC) opposite the immunological synapse via association with the... | |||
TMPY-03296 | SHP-1 Protein, Mouse, Recombinant (aa 207-597, His & GST) | Mouse | Baculovirus-Insect Cells |
PTPN6 is an enzyme that belongs to the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and onco... | |||
TMPJ-00396 | SEMA4D Protein, Human, Recombinant (aa 22-734, His) | Human | Human Cells |
Semaphorin-4D is also known as A8,BB18, GR3, CD100. Semaphorin-4D belongs to the semaphorin family containing 1 Ig-like C2-type domain, 1 PSI domain and 1 Sema domain. It is the cell surface receptor for PLXN1B and PLXNB... | |||
TMPY-02435 | CD43 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
CD43 is an abundantly expressed molecule on the T-cell surface that shows distinct localization to the migrating T-cell uropod and the distal pole complex (DPC) opposite the immunological synapse via association with the... | |||
TMPJ-00326 | CD122/IL2RB Protein, Human, Recombinant (aa 27-239, His & Avi), Biotinylated | Human | Human Cells |
Human IL-2RB, also known asinterleukin-2 receptor subunit beta,is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 recepto... | |||
TMPY-02191 | BLNK Protein, Human, Recombinant (His) | Human | HEK293 |
B-cell linker protein, also known as B-cell adapter containing a SH2 domain protein, B-cell adapter containing a Src homology 2 domain protein, Cytoplasmic adapter protein, Src homology 2 domain-containing leukocyte p... | |||
TMPH-01961 | Wnt3a Protein, Human, Recombinant (His) | Human | E. coli |
Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are tra... | |||
TMPH-02192 | Tetraspanin-7/TSPAN7 Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are tra... | |||
TMPH-02631 | PRKN Protein, Mouse, Recombinant (GST) | Mouse | E. coli |
Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are tra... | |||
TMPJ-00776 | HER2/ERBB2 Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | Human Cells |
Human epidermal growth factor receptor 2 (HER2) is a type of membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 plays a key role in development, cell proliferation and different... | |||
TMPJ-00329 | CD19 Protein, Rhesus macaque, Recombinant (hFc) | Rhesus macaque | Human Cells |
CD19 is a single-pass type I membrane protein containing 2 Ig-like C2-type (immunoglobulin-like) domains. CD19 is expressed on follicular dendritic cells and B cells. In fact, it is present on B cells from earliest recog... | |||
TMPY-01715 | CDC37 Protein, Human, Recombinant (GST) | Human | Baculovirus-Insect Cells |
CDC37 is a protein that is expressed in proliferative zones during embryonic development and in adult tissues, consistent with a positive role in proliferation and is required for cell division in budding yeast. CDC37 is... | |||
TMPJ-00777 | HER2/ERBB2 Protein, Human, Recombinant (aa 23-652, hFc) | Human | Human Cells |
Human epidermal growth factor receptor 2 (HER2) is a type of membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 plays a key role in development, cell proliferation and different... | |||
TMPY-03534 | CDC37 Protein, Mouse, Recombinant (His & GST) | Mouse | Baculovirus-Insect Cells |
CDC37 is a protein that is expressed in proliferative zones during embryonic development and in adult tissues, consistent with a positive role in proliferation and is required for cell division in budding yeast. CDC37 is... | |||
TMPY-01809 | SLAMF6 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
SLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly18, is a single-pass type I membrane protein that belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAM... | |||
TMPY-03766 | SLAMF6 Protein, Human, Recombinant (hFc) | Human | HEK293 |
SLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly18, is a single-pass type I membrane protein that belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAM... | |||
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Cat No. | Product Name | ||
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L1610 | FDA-Approved Kinase Inhibitor Library | 280 compounds | |
Targetmol’s FDA-Approved Kinase Inhibitor Library contains 280 marketed drugs with proven kinase inhibitory activity. These kinases include Insulin/IGF Receptors、PI 3-Kinase、CaM Kinase II、JAK、PKA、CDK、JNK、PKC、CKI II、MAPK、... | |||
L1600 | Kinase Inhibitor Library | 2230 compounds | |
A unique collection of 2230 kinase inhibitors for high throughput screening and high content screening for drug discovery in kinase related diseases; |