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Search Results for " src "

Targets

203

Compounds

13

Natural Products

99

Recombinant Proteins

2

Libraries

Cat No. Product Name Synonyms Targets
T3593 Src Inhibitor 1 Src Kinase Inhibitor 1,Src-l1 Src
Src Inhibitor 1 (Src Kinase Inhibitor 1) is a potent and selective dual site Src tyrosine kinase inhibitor.
TP2289L RR-src acetate RR-src acetate(81156-93-6 Free base) Others
RR-src acetate is a synthetic peptide derived from the amino acid sequence surrounding the phosphorylation site in pp60src.
T13000 Src Inhibitor 3 Others , Src
Src Inhibitor 3 is an effective inhibitor of c-terminal Src kinase (IC50 <3 nM in CSK HTRF, <4 nM in Caliper assay). Src Inhibitor 3 increases T cell proliferation induced by T cell receptor signaling.
TP2137L Pp60 c-src (521-533) (phosphorylated) acetate Others
pp60 c-src (521-533) (phosphorylated) acetate is a regulator of focal adhesion formation and cell spreading. pp60 c-src (521-533) (phosphorylated) acetate also regulates cell motility and is a key component in the signal...
T39185 Pp60 (v-SRC) Autophosphorylation Site, Phosphorylated pp60 (v-SRC) Autophosphorylation Site, Phosphorylated
pp60 (v-SRC) Autophosphorylation Site, Phosphorylated is a phosphorylated peptide derived from an EGFR substrate. It serves as a valuable tool for quantifying phosphorylated substrates in screening EGFR Kinase inhibitors...
T11745 KB SRC 4 Src
KB SRC 4 is a selective and potent c-Src inhibitor with antitumour activity that inhibits the growth of cancer cells.
T39149 Src Optimal Peptide Substrate
Src Optimal Peptide Substrate, a highly specific substrate of Src, serves as a reliable indicator of Src activity. It enables accurate assessment of Src kinase function.
TP2289 RR-src Others
Tyrosine kinase substrate peptide
T1811 WH-4-023 KIN112,KIN001-112,Dual LCK/SRC inhibitor Src
WH-4-023 (Dual LCK/SRC inhibitor) is a potent and orally active Lck/Src inhibitor. It also potently inhibits SIK.
T13062 T338C Src-IN-2 Others
T338C Src-IN-2 is a potent mutant inhibitor of c-Src T338C kinase(IC50 of 317 nM). T338C Src-IN-2 also inhibits T338C/V323A and T338C/V323S(IC50 of 57 nM/19 nM,respectively).
T13061 T338C Src-IN-1 Others
T338C Src-IN-1 is a potent mutant-Src T338C inhibitor(T338C,IC50=111 nM relative to WT c-Src (10-fold increase)).
TP2137 Pp60 c-src (521-533) (phosphorylated)
Peptide corresponding to the pp60c-src carboxy terminal regulatory domain; phosphorylated at Tyr527. Binds to pp60c-src and pp60v-src at the SH2 domain, suppressing their tyrosine kinase activity and transforming potenti...
T76391 P60c-src substrate II
p60c-src substrate II is an efficient pentapeptide substrate for the tyrosine kinase pp60c-src [1] .
T81577 P60v-src(137-157)
P60v-src(137-157) is a synthetic peptide that serves as an inhibitor of the tyrosine kinase activity of p60 v-src, with an IC50 value of 7.5 μM [1] [2].
T81106 SRC-1 (686-700)
SRC-1 (686-700) is a bioactive peptide encompassing amino acids 686 to 700, which include the second LXXLL motif from NR box II of steroid receptor coactivator (SRC1). These coactivator proteins facilitate transcription ...
T81578 P60c-src substrate II, phosphorylated
Phosphorylated p60c-src substrate II is a pentapeptide and a phosphorylated polypeptide form of p60c-src substrate II. Phosphorylation is a critical post-translational modification (post-translationmodification) vital fo...
T83752 Biotin-SRC-1 (676–700) TFA Biotin-Steroid Receptor Coactivator 1 (676-700)
Biotin-SRC-1 (676–700), a biotinylated and truncated variant of steroid receptor coactivator 1 (SRC-1), finds application in affinity-based reporter assays such as time-resolved FRET (TR-FRET) and amplified luminescent p...
T0152 Bosutinib SKI-606 Bcr-Abl , Src , Autophagy
Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50: 1 nM) and Src (IC50: 1.2 nM) kinases.
T8499 ECF506 Src
eCF506 is a potent and selective inhibitor of SRC (IC50 < 0.5 nM)
T17267 XL228 IGF-1R , Bcr-Abl , Src , Aurora Kinase
XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).
T3063 PD173955 PD-173955,PD 173955 Apoptosis , Bcr-Abl , Src
PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes and Abl kinase; less potent for FGFRα and no activity on InsR and PKC.
T6078 Saracatinib AZD0530 EGFR , Src , BTK , Autophagy
Saracatinib (AZD0530) (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes.
T13186 TL02-59 Apoptosis , Src , Hck
TL02-59 is a selective inhibitor of Fgr in Src-family kinase (IC50 = 0.03 nM). TL02-59 inhibits Lyn and Hck with IC50s of 0.1 nM and 160 nM, respectively. TL02-59 potently suppresses acute myelogenous leukemia cell growt...
T4301 AD80 Raf , c-RET , Src , S6 Kinase
AD80, a multikinase inhibitor, inhibits RET, RAF, SRCand S6K, with greatly reduced mTOR activity.
T4470 Pyridostatin TFA DNA/RNA Synthesis
Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-kit, K-ras and Bcl-2.
T6594 MNS Syk , Src , p97
MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.
T11538 Hck-IN-1 HIV Protease , Src , Hck
Hck-IN-1 is a selective Nef-dependent Hck inhibitor (IC50s: 2.8 μM and >20 μM for Nef:Hck complex and Hck) with antiretroviral activity. Hck-IN-1 is a direct and wide HIV-1 Nef antagonist with an IC50 of 100-300 nM for w...
T6345 Tirbanibulin KX2-391,KX-01 Microtubule Associated , Src
Tirbanibulin (KX2-391) is a highly selective Src kinase inhibitor that has demonstrated efficacy in pre-Clinicalal animal models of colon, pancreatic, prostate and breast cancer. It is a substrate-targeted kinase inhibit...
T4597 UM-164 UM164,DAS-DFGO-II p38 MAPK , Src , Autophagy
UM-164 (DAS-DFGO-II) is a highly potent inhibitor of c-Src with a Kd of 2.7 nM. UM-164 also potently inhibits p38α and p38β.
T2153 1-NM-PP1 PP1 Analog II,1 nM-PP1 Serine/threonin kinase , CDK , Src
1-NM-PP1 (PP1 Analog II) is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors.
T6997 SU6656 FAK , Akt , Src
SU 6656 is a selective inhibitor of Src family kinases, with IC50 of 280 nM, 20 nM, 130 nM, and 170 nM for Src, Yes, Lyn, and Fyn, respectively.
T1812 KX1-004 KX1 004,KX1004 Src
KX1-004, a potential protective drug for NIHL, is an effective small molecule inhibitor of Src-PTK.
T13194 CSF1R-IN-2 c-Fms , c-Met/HGFR , Src
CSF1R-IN-2 is an oral-active SRC, MET and c-FMS inhibitor (IC50s: 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively).
T2415 PP121 Apoptosis , VEGFR , Bcr-Abl , PDGFR , Src , mTOR , Hck
PP-121 is a multi-targeted inhibitor of PDGFR (IC50: 2 nM), Hck (IC50: 8 nM), mTOR (IC50: 10 nM), VEGFR2(IC50: 12 nM), Src (IC50: 14 nM) and Abl (IC50: 18 nM) , also inhibits DNA-PK (IC50: 60 nM).
T7123 AMG-47a VEGFR , p38 MAPK , JAK , Src
AMG-47a is a potent inhibitor of Lck and T cell proliferation. AMG-47a could promote the degradation of the KRAS oncoprotein. AMG-47a selectively reduced the levels of EGFP-KRASG12V protein but did not affect EGFP protei...
T2640 Rebastinib DCC2036,DCC 2036,DCC-2036 Apoptosis , FLT , Bcr-Abl , Src
DCC-2036 (Rebastinib (DCC-2036)) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50: 0.8 nM) and Abl1(T315I, IC50: 4 nM), also inhibits LYN, SRC, HCK, FGR, FLT3, KDR, and Tie-2, and low activity to c-Kit. Re...
T1448 Dasatinib BMS-354825 Apoptosis , Bcr-Abl , Src , c-Kit , Autophagy
Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive. Dasatinib has antitumor activity and is used in the treatment of leukemia and ly...
T6196 PP1 EI 275,AGL 1872 Apoptosis , EGFR , Bcr-Abl , Src , c-Kit
PP1 (AGL 1872), a specific and effective Src inhibitor, is with IC50 for Lck/Fyn is 5 nM/ 6 nM, respectively.
T15675 Tirbanibulin Mesylate KX2-391 Mesylate,KX01 Mesylate Microtubule Associated , Src
Tirbanibulin Mesylate (KX01 Mesylate) is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).
TQ0132 A 419259 trihydrochloride RK 20449 trihydrochloride Src
A 419259 trihydrochloride (RK 20449 trihydrochloride) is an Src family kinases inhibitor (IC50s: 9 nM, 3 nM and 3 nM for Src, Lck and Lyn).
T8719 SC99 Apoptosis , JAK , STAT
SC99 is a selective inhibitor of JAK2-STAT3 activation. SC99 downregulates the expression of STAT3-modulated genes.SC99 inhibits platelet activation, aggregation and displays potent anti-myeloma, anti-thrombotic activiti...
T6896 Tolimidone NSC 314335,MLR-1023,CP-26154 Src
Tolimidone (NSC 314335) is a chemical compound which inhibits acid secretion in animal models and also acts as a bronchodilator in histamine-challenged animals.
T3935 1-Naphthyl PP1 1-NA-PP 1 Src
1-Naphthyl PP1 (1-NA-PP 1) is a selective src inhibitor(v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively)
T11826 LCH-7749944 GNF-PF-2356 Apoptosis , PAK
LCH-7749944 (GNF-PF-2356) effectively suppresses the proliferation of human gastric cancer cells through downregulation of PAK4/c-Src/EGFR/cyclin D1 pathway and induces apoptosis. LCH-7749944 is a potent PAK4 inhibitor w...
T6311 Bafetinib NS-187,INNO-406 Bcr-Abl , Src , Autophagy
Bafetinib (INNO-406) (INNO-406) is an effective and specific dual Bcr-Abl/Lyn inhibitor (IC50: 5.8/19 nM), and no inhibition of the phosphorylation of the T315I mutant and less effective to c-Kit and PDGFR.
T8976 PD-089828 EGFR , FGFR , PDGFR , Src
PD 089828 is a competitive inhibitor of the receptor tyrosine kinases FGFR1, PDGFRβ, and EGFR (IC50s = 0.15, 1.76, and 5.47 µM, respectively) and a noncompetitive inhibitor of the nonreceptor tyrosine kinase c-Src (IC50 ...
T2358 ENMD-2076 Apoptosis , VEGFR , FGFR , FLT , c-RET , PDGFR , Src , Aurora Kinase
ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.
T2327 Pelitinib EKB-569,WAY-EKB 569 EGFR , Raf , MEK , Src
Pelitinib (EKB-569) (EKB-569) is an effective irreversible EGFR inhibitor (IC50: 38.5 nM).
T0948 Adrenalone hydrochloride Adrenalone HCl Adrenergic Receptor
Adrenalone hydrochloride (Adrenalone HCl) is a dopamine β-oxidase inhibitor with a similar structure to the norepinephrine transporter (NET) ligand, with an IC50 of 36.9 μM. It is an adrenergic agonist that acts as a loc...
T6266 PP2 AGL 1879,AG 1879,AGL 1879 EGFR , Tyrosine Kinases , JAK , Src
PP2 (AG 1879,AGL 1879) is a effective inhibitor of Lck/Fyn (IC50:4/5 nM) , ~100-fold less potent to EGFR, inactive for ZAP-70, PKA and JAK2.

Compounds

Src Inhibitor 1
T3593
Synonym: Src Kinase Inhibitor 1,Src-l1
Target: Src
RR-src acetate
TP2289L
Synonym: RR-src acetate(81156-93-6 Free base)
Target: Others
Src Inhibitor 3
T13000
Synonym:
Target: Others, Src
pp60 c-src (521-533) (phosphorylated) acetate
TP2137L
Synonym:
Target: Others
pp60 (v-SRC) Autophosphorylation Site, Phosphorylated
T39185
Synonym: pp60 (v-SRC) Autophosphorylation Site, Phosphorylated
Target:
KB SRC 4
T11745
Synonym:
Target: Src
Src Optimal Peptide Substrate
T39149
Synonym:
Target:
RR-src
TP2289
Synonym:
Target: Others
WH-4-023
T1811
Synonym: KIN112,KIN001-112,Dual LCK/SRC inhibitor
Target: Src
T338C Src-IN-2
T13062
Synonym:
Target: Others
T338C Src-IN-1
T13061
Synonym:
Target: Others
pp60 c-src (521-533) (phosphorylated)
TP2137
Synonym:
Target:
p60c-src substrate II
T76391
Synonym:
Target:
P60v-src(137-157)
T81577
Synonym:
Target:
SRC-1 (686-700)
T81106
Synonym:
Target:
p60c-src substrate II, phosphorylated
T81578
Synonym:
Target:
Biotin-SRC-1 (676–700) TFA
T83752
Synonym: Biotin-Steroid Receptor Coactivator 1 (676-700)
Target:
Bosutinib
T0152
Synonym: SKI-606
Target: Bcr-Abl, Src, Autophagy
eCF506
T8499
Synonym:
Target: Src
XL228
T17267
Synonym:
Target: IGF-1R, Bcr-Abl, Src, Aurora Kinase
PD173955
T3063
Synonym: PD-173955,PD 173955
Target: Apoptosis, Bcr-Abl, Src
Saracatinib
T6078
Synonym: AZD0530
Target: EGFR, Src, BTK, Autophagy
TL02-59
T13186
Synonym:
Target: Apoptosis, Src, Hck
AD80
T4301
Synonym:
Target: Raf, c-RET, Src, S6 Kinase
Pyridostatin TFA
T4470
Synonym:
Target: DNA/RNA Synthesis
MNS
T6594
Synonym:
Target: Syk, Src, p97
Hck-IN-1
T11538
Synonym:
Target: HIV Protease, Src, Hck
Tirbanibulin
T6345
Synonym: KX2-391,KX-01
Target: Microtubule Associated, Src
UM-164
T4597
Synonym: UM164,DAS-DFGO-II
Target: p38 MAPK, Src, Autophagy
1-NM-PP1
T2153
Synonym: PP1 Analog II,1 nM-PP1
Target: Serine/threonin kinase, CDK, Src
SU6656
T6997
Synonym:
Target: FAK, Akt, Src
KX1-004
T1812
Synonym: KX1 004,KX1004
Target: Src
CSF1R-IN-2
T13194
Synonym:
Target: c-Fms, c-Met/HGFR, Src
PP121
T2415
Synonym:
Target: Apoptosis, VEGFR, Bcr-Abl, PDGFR, Src, mTOR, Hck
AMG-47a
T7123
Synonym:
Target: VEGFR, p38 MAPK, JAK, Src
Rebastinib
T2640
Synonym: DCC2036,DCC 2036,DCC-2036
Target: Apoptosis, FLT, Bcr-Abl, Src
Dasatinib
T1448
Synonym: BMS-354825
Target: Apoptosis, Bcr-Abl, Src, c-Kit, Autophagy
PP1
T6196
Synonym: EI 275,AGL 1872
Target: Apoptosis, EGFR, Bcr-Abl, Src, c-Kit
Tirbanibulin Mesylate
T15675
Synonym: KX2-391 Mesylate,KX01 Mesylate
Target: Microtubule Associated, Src
A 419259 trihydrochloride
TQ0132
Synonym: RK 20449 trihydrochloride
Target: Src
SC99
T8719
Synonym:
Target: Apoptosis, JAK, STAT
Tolimidone
T6896
Synonym: NSC 314335,MLR-1023,CP-26154
Target: Src
1-Naphthyl PP1
T3935
Synonym: 1-NA-PP 1
Target: Src
LCH-7749944
T11826
Synonym: GNF-PF-2356
Target: Apoptosis, PAK
Bafetinib
T6311
Synonym: NS-187,INNO-406
Target: Bcr-Abl, Src, Autophagy
PD-089828
T8976
Synonym:
Target: EGFR, FGFR, PDGFR, Src
ENMD-2076
T2358
Synonym:
Target: Apoptosis, VEGFR, FGFR, FLT, c-RET, PDGFR, Src, Aurora Kinase
Pelitinib
T2327
Synonym: EKB-569,WAY-EKB 569
Target: EGFR, Raf, MEK, Src
Adrenalone hydrochloride
T0948
Synonym: Adrenalone HCl
Target: Adrenergic Receptor
PP2
T6266
Synonym: AGL 1879,AG 1879,AGL 1879
Target: EGFR, Tyrosine Kinases, JAK, Src
1 2 3 4 5
Cat No. Product Name Synonyms Targets
T5S1982 Periplocin Periplocoside Apoptosis , Others
1. Periplocin (Periplocoside) has anti-cancer effects on lung cancer cells, induces apoptosis and inhibits growth of cancer cells by the beta-catenin/Tcf signaling pathway. 2. Periplocin is used for treatment of rheumato...
TN1440 Beta-Hydroxyisovalerylshikonin EGFR , Tyrosine Kinases , Prostaglandin Receptor , Src , AMPK , Fatty Acid Synthase
Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumor cell lines. Beta-Hydroxyisovalerylshikonin significantly de...
TN2269 Tetramethylcurcumin Apoptosis , STAT
Tetramethylcurcumin is a novel curcumin analog, is an effective inhibitors of STAT3 phosphorylation, DNA binding activity, and transactivation in vitro.it also inhibits colony formation in soft agar, cell invasion, and e...
T3319 Scutellarein 4',5,6,7-Tetrahydroxyflavone,6-Hydroxyapigenin SARS-CoV , Src , Autophagy
Scutellarein (6-Hydroxyapigenin) reduces inflammatory responses by inhibiting Src kinase activity.
T7345 7-Hydroxy-4H-chromen-4-one 7-hydroxy-4-benzopyrone,7-Hydroxy-4-chromone,7-Hydroxychromone Src
7-Hydroxy-4H-chromen-4-one (7-hydroxy-4-benzopyrone) is a Src kinase inhibitor (IC50 of <300 μM).
TN1892 Lusianthridin Others , c-Myc
Lusianthridin is a natural product from Dendrobium venustum. Lusianthridin exhibits anti-migratory property at nontoxic concentrations. Lusianthridin enhances c-Myc degradation through the inhibition of Src-STAT3 signali...
TQ0169 Inulicin 1-O-Acetylbritannilactone FAK , NF-κB , COX , Src
Inulicin (1-O-Acetylbritannilactone), an active compound isolated from Inula Britannica L, inhibits VEGF-mediated activation of Src and FAK.
T3S2390 Caftaric acid trans-Caftaric acid Others
Caftaric acid (trans-Caftaric acid) is a natural product with antioxidant and anti-inflammatory properties, antimutagenicity, and an inhibitor of protein-protein interactions mediated by Src family kinases.
TN1244 3'-Demethylnobiletin LDL , NF-κB , Integrin , Lipoxygenase , DNA/RNA Synthesis
3'-Demethylnobiletin has chemopreventive effects on colon carcinogenesis, it can significantly inhibit the growth of human colon cancer cells, cause cell-cycle arrest, induce apoptosis, and profoundly modulate signaling ...
T5S0761 Nitidine chloride Apoptosis , ERK , FAK , p38 MAPK , NF-κB , Topoisomerase , STAT , Parasite
1. Nitidine chloride has inhibitory effects on various tumors, such as renal cancer , breast cancer. 2. Nitidine chloride inhibits the proliferation of SMMC-7721 cells in vitro in a time- and dose-dependent manner and id...
T6427 Butein 2’,3,4,4’-tetrahydroxy Chalcone Apoptosis , EGFR , Others , PDE , Autophagy
Butein (2’,3,4,4’-tetrahydroxy Chalcone), a plant polyphenol, is isolated from Rhus verniciflua. It can inhibit the activation of protein tyrosine kinase, NF-κB and STAT3, and also can inhibit EGFR.
TN1143 1-O-Acetyl britannilactone NF-κB , COX
1-O-Acetyl britannilactone shows antifungal, and anti-cancer activities, it suppresses angiogenesis and lung cancer cell growth possibly via regulating the VEGFR-Src-FAK signaling.
T14055 5Z-7-Oxozeaenol FR148083,L783279,LL-Z 1640-2 VEGFR , FLT , MEK , MAPK , PDGFR , Antibiotic , Src
5Z-7-Oxozeaenol (FR148083) is a potent, irreversible and selective inhibitor of transforming growth factor (TGF)-β-activated kinase 1 with IC50 of 8.1 nM for TAK1 and low activity against MEK1 with IC50 of 411 nM, it is ...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-04384 Src Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
Proto-oncogene tyrosine-protein kinase SRC is a hydrophobic protein belonging to the SRC family kinase including nine members that is a family of non-receptor tyrosine kinases. SRC protein may exist in different forms: C...
TMPY-04434 Src Protein, Mouse, Recombinant (His & GST) Mouse Baculovirus-Insect Cells
Proto-oncogene tyrosine-protein kinase SRC is a hydrophobic protein belonging to the SRC family kinase including nine members that is a family of non-receptor tyrosine kinases. SRC protein may exist in different forms: C...
TMPH-01977 Src Protein, Human, Recombinant (His) Human E. coli
May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated ...
TMPY-04383 CSK Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
The tyrosine kinase c-Src has been implicated as a modulator of cell proliferation, spreading, and migration. These functions are also regulated by Met. The structure of a large fragment of the c-Src kinase comprises the...
TMPY-04444 CSK Protein, Mouse, Recombinant (His & GST) Mouse Baculovirus-Insect Cells
The tyrosine kinase c-Src has been implicated as a modulator of cell proliferation, spreading, and migration. These functions are also regulated by Met. The structure of a large fragment of the c-Src kinase comprises the...
TMPY-04760 CSK Protein, Mouse, Recombinant Mouse Baculovirus-Insect Cells
The tyrosine kinase c-Src has been implicated as a modulator of cell proliferation, spreading, and migration. These functions are also regulated by Met. The structure of a large fragment of the c-Src kinase comprises the...
TMPY-04388 BLK Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
Tyrosine-protein kinase Blk, also known as B lymphocyte kinase, p55-Blk and BLK, is a member of theprotein kinase superfamily, Tyr protein kinase family and SRC subfamily. BLK / p55-Blk is expressed in lymphatic organ...
TMPY-04391 Lyn Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
Tyrosine-protein kinase Lyn is a member of the Src family of protein tyrosine kinases, which is mainly expressed in hematopoietic cells, in neural tissues liver, and adipose tissue. Tyrosine-protein kinase Lyn has many f...
TMPY-04411 YES1 Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
Proto-oncogene tyrosine-protein kinase Yes, also known as Proto-oncogene c-Yes, p61-Yes and YES1, is a cytoplasm protein that belongs to the protein kinase superfamily, Tyr protein kinase family and SRC subfamily. YES1 /...
TMPJ-00778 HER2/ERBB2 Protein, Human, Recombinant (His) Human Human Cells
Human epidermal growth factor receptor 2 (HER2) is a type of membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 plays a key role in development, cell proliferation and different...
TMPY-03835 CDCP1 Protein, Rhesus, Recombinant (His) Rhesus HEK293
CDCP1 contains three extracellular CUB domains. It is a putative stem cell marker that is highly expressed in some human cancer cells and both, typical and atypical (cancerous) colons. It interacts with CDH2/N-cadherin, ...
TMPY-04298 CDCP1 Protein, Human, Recombinant (His) Human HEK293
CDCP1 contains three extracellular CUB domains. It is a putative stem cell marker that is highly expressed in some human cancer cells and both, typical and atypical (cancerous) colons. It interacts with CDH2/N-cadherin, ...
TMPY-05308 CD45 Protein, Human, Recombinant (aa 1-529, His) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-05748 CD45 Protein, Human, Recombinant (aa 26-577, His) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-02005 Mucin-1/MUC1 Protein, Human, Recombinant (hFc) Human HEK293
Mucin 1, cell surface-associated (MUC1) or polymorphic epithelial mucin (PEM) is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming pr...
TMPY-05201 Siglec-2/CD22 Protein, Human, Recombinant Human HEK293
CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. CD22 serves as an adhesi...
TMPY-04083 Siglec-2/CD22 Protein, Mouse, Recombinant (His) Mouse HEK293
CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. CD22 serves as an adhesi...
TMPY-05566 Siglec-2/CD22 Protein, Human, Recombinant (His, Solution) Human HEK293
CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. CD22 serves as an adhesi...
TMPY-02034 Siglec-2/CD22 Protein, Human, Recombinant (His) Human HEK293
CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. CD22 serves as an adhesi...
TMPY-04340 Mucin-1/MUC1 Protein, Human, Recombinant Human HEK293
Mucin 1, cell surface-associated (MUC1) or polymorphic epithelial mucin (PEM) is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming pr...
TMPH-02043 RHOD Protein, Human, Recombinant (His & Myc) Human E. coli
May regulate the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors.
TMPY-02511 PTP alpha/PTPRA Protein, Human, Recombinant (aa 174-793, His & GST) Human Baculovirus-Insect Cells
PTPRA is reported to be involved in cancer development and progression through activating the Src family kinase (SFK) signaling pathways. The higher PTPRA level was associated with worse prognosis of SCC patients and PTP...
TMPJ-00712 MPZL1 Protein, Human, Recombinant (His) Human Human Cells
Myelin protein zero-like protein 1(MPZL1) is encoded by the MPZL1 gene, which is a single-pass type I membrane protein. It is widely expressed with highest levels in heart, placenta, kidney and pancreas. As cell surface ...
TMPJ-00184 CD20 Protein, Human, Recombinant (Flag) Human Human Cells
CD20 is a 33-37 kDa non-glycosylated protein expressed on the surface of normal and malignant B lymphocytes, and belongs to the MS4A (membrane-spanning 4-domain family A) protein family. CD20 protein consists of four hyd...
TMPH-00926 MAOB Protein, Human, Recombinant (His) Human E. coli
Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including neurogenesis, vascular development, angiogenesis and osteogenesis. Acts in concert with PTHLH/PTHRP to stimu...
TMPH-01288 Elongin-B Protein, Human, Recombinant (GST) Human E. coli
Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to ...
TMPK-00423 CD45 Protein, Human, Recombinant (His & Avi) Human HEK293
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) com...
TMPJ-00185 CD20 Protein, Human, Recombinant (His & Flag) Human Human Cells
CD20 is a 33-37 kDa non-glycosylated protein expressed on the surface of normal and malignant B lymphocytes, and belongs to the MS4A (membrane-spanning 4-domain family A) protein family. CD20 protein consists of four hyd...
TMPY-02761 Rack1 Protein, Human, Recombinant (His & MBP) Human E. coli
The scaffolding protein, Rack1, is a seven-WD-domain-containing protein that has been implicated in binding to integrin beta subunit cytoplasmic domains and to members of two kinase families (src and protein kinase C, PK...
TMPK-00457 HGFR/c-Met Protein, Human, Recombinant (His & Avi) Human HEK293
c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene.The protein possesses tyrosine kinase activity. The primary single chain ...
TMPK-00447 CD45 Protein, Human, Recombinant (aa 26-577, hFc) Human HEK293
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) com...
TMPK-00424 CD45 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) com...
TMPY-03510 Cbl-c Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
CBL proteins, such as Cbl-c, are phosphorylated upon activation of a variety of receptors that signal via protein tyrosine kinases. Through interactions with proteins containing SRC homology-2 (SH2) and SH3 domains, C...
TMPK-00499 HGFR/c-Met Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene.The protein possesses tyrosine kinase activity. The primary single chain ...
TMPY-03824 CD43 Protein, Rat, Recombinant (hFc) Rat HEK293
CD43 is an abundantly expressed molecule on the T-cell surface that shows distinct localization to the migrating T-cell uropod and the distal pole complex (DPC) opposite the immunological synapse via association with the...
TMPY-03296 SHP-1 Protein, Mouse, Recombinant (aa 207-597, His & GST) Mouse Baculovirus-Insect Cells
PTPN6 is an enzyme that belongs to the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and onco...
TMPJ-00396 SEMA4D Protein, Human, Recombinant (aa 22-734, His) Human Human Cells
Semaphorin-4D is also known as A8,BB18, GR3, CD100. Semaphorin-4D belongs to the semaphorin family containing 1 Ig-like C2-type domain, 1 PSI domain and 1 Sema domain. It is the cell surface receptor for PLXN1B and PLXNB...
TMPY-02435 CD43 Protein, Mouse, Recombinant (hFc) Mouse HEK293
CD43 is an abundantly expressed molecule on the T-cell surface that shows distinct localization to the migrating T-cell uropod and the distal pole complex (DPC) opposite the immunological synapse via association with the...
TMPJ-00326 CD122/IL2RB Protein, Human, Recombinant (aa 27-239, His & Avi), Biotinylated Human Human Cells
Human IL-2RB, also known asinterleukin-2 receptor subunit beta,is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 recepto...
TMPY-02191 BLNK Protein, Human, Recombinant (His) Human HEK293
B-cell linker protein, also known as B-cell adapter containing a SH2 domain protein, B-cell adapter containing a Src homology 2 domain protein, Cytoplasmic adapter protein, Src homology 2 domain-containing leukocyte p...
TMPH-01961 Wnt3a Protein, Human, Recombinant (His) Human E. coli
Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are tra...
TMPH-02192 Tetraspanin-7/TSPAN7 Protein, Human, Recombinant (E. coli, His) Human E. coli
Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are tra...
TMPH-02631 PRKN Protein, Mouse, Recombinant (GST) Mouse E. coli
Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are tra...
TMPJ-00776 HER2/ERBB2 Protein, Human, Recombinant (hFc & Avi), Biotinylated Human Human Cells
Human epidermal growth factor receptor 2 (HER2) is a type of membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 plays a key role in development, cell proliferation and different...
TMPJ-00329 CD19 Protein, Rhesus macaque, Recombinant (hFc) Rhesus macaque Human Cells
CD19 is a single-pass type I membrane protein containing 2 Ig-like C2-type (immunoglobulin-like) domains. CD19 is expressed on follicular dendritic cells and B cells. In fact, it is present on B cells from earliest recog...
TMPY-01715 CDC37 Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
CDC37 is a protein that is expressed in proliferative zones during embryonic development and in adult tissues, consistent with a positive role in proliferation and is required for cell division in budding yeast. CDC37 is...
TMPJ-00777 HER2/ERBB2 Protein, Human, Recombinant (aa 23-652, hFc) Human Human Cells
Human epidermal growth factor receptor 2 (HER2) is a type of membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 plays a key role in development, cell proliferation and different...
TMPY-03534 CDC37 Protein, Mouse, Recombinant (His & GST) Mouse Baculovirus-Insect Cells
CDC37 is a protein that is expressed in proliferative zones during embryonic development and in adult tissues, consistent with a positive role in proliferation and is required for cell division in budding yeast. CDC37 is...
TMPY-01809 SLAMF6 Protein, Mouse, Recombinant (His) Mouse HEK293
SLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly18, is a single-pass type I membrane protein that belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAM...
TMPY-03766 SLAMF6 Protein, Human, Recombinant (hFc) Human HEK293
SLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly18, is a single-pass type I membrane protein that belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAM...
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Src Protein, Human, Recombinant (His & GST)
TMPY-04384
Species: Human
Expression System: Baculovirus-Insect Cells
Src Protein, Mouse, Recombinant (His & GST)
TMPY-04434
Species: Mouse
Expression System: Baculovirus-Insect Cells
Src Protein, Human, Recombinant (His)
TMPH-01977
Species: Human
Expression System: E. coli
CSK Protein, Human, Recombinant (GST)
TMPY-04383
Species: Human
Expression System: Baculovirus-Insect Cells
CSK Protein, Mouse, Recombinant (His & GST)
TMPY-04444
Species: Mouse
Expression System: Baculovirus-Insect Cells
CSK Protein, Mouse, Recombinant
TMPY-04760
Species: Mouse
Expression System: Baculovirus-Insect Cells
BLK Protein, Human, Recombinant (GST)
TMPY-04388
Species: Human
Expression System: Baculovirus-Insect Cells
Lyn Protein, Human, Recombinant (GST)
TMPY-04391
Species: Human
Expression System: Baculovirus-Insect Cells
YES1 Protein, Human, Recombinant (His & GST)
TMPY-04411
Species: Human
Expression System: Baculovirus-Insect Cells
HER2/ERBB2 Protein, Human, Recombinant (His)
TMPJ-00778
Species: Human
Expression System: Human Cells
CDCP1 Protein, Rhesus, Recombinant (His)
TMPY-03835
Species: Rhesus
Expression System: HEK293
CDCP1 Protein, Human, Recombinant (His)
TMPY-04298
Species: Human
Expression System: HEK293
CD45 Protein, Human, Recombinant (aa 1-529, His)
TMPY-05308
Species: Human
Expression System: HEK293
CD45 Protein, Human, Recombinant (aa 26-577, His)
TMPY-05748
Species: Human
Expression System: HEK293
Mucin-1/MUC1 Protein, Human, Recombinant (hFc)
TMPY-02005
Species: Human
Expression System: HEK293
Siglec-2/CD22 Protein, Human, Recombinant
TMPY-05201
Species: Human
Expression System: HEK293
Siglec-2/CD22 Protein, Mouse, Recombinant (His)
TMPY-04083
Species: Mouse
Expression System: HEK293
Siglec-2/CD22 Protein, Human, Recombinant (His, Solution)
TMPY-05566
Species: Human
Expression System: HEK293
Siglec-2/CD22 Protein, Human, Recombinant (His)
TMPY-02034
Species: Human
Expression System: HEK293
Mucin-1/MUC1 Protein, Human, Recombinant
TMPY-04340
Species: Human
Expression System: HEK293
RHOD Protein, Human, Recombinant (His & Myc)
TMPH-02043
Species: Human
Expression System: E. coli
PTP alpha/PTPRA Protein, Human, Recombinant (aa 174-793, His & GST)
TMPY-02511
Species: Human
Expression System: Baculovirus-Insect Cells
MPZL1 Protein, Human, Recombinant (His)
TMPJ-00712
Species: Human
Expression System: Human Cells
CD20 Protein, Human, Recombinant (Flag)
TMPJ-00184
Species: Human
Expression System: Human Cells
MAOB Protein, Human, Recombinant (His)
TMPH-00926
Species: Human
Expression System: E. coli
Elongin-B Protein, Human, Recombinant (GST)
TMPH-01288
Species: Human
Expression System: E. coli
CD45 Protein, Human, Recombinant (His & Avi)
TMPK-00423
Species: Human
Expression System: HEK293
CD20 Protein, Human, Recombinant (His & Flag)
TMPJ-00185
Species: Human
Expression System: Human Cells
Rack1 Protein, Human, Recombinant (His & MBP)
TMPY-02761
Species: Human
Expression System: E. coli
HGFR/c-Met Protein, Human, Recombinant (His & Avi)
TMPK-00457
Species: Human
Expression System: HEK293
CD45 Protein, Human, Recombinant (aa 26-577, hFc)
TMPK-00447
Species: Human
Expression System: HEK293
CD45 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00424
Species: Human
Expression System: HEK293
Cbl-c Protein, Human, Recombinant (His & GST)
TMPY-03510
Species: Human
Expression System: Baculovirus-Insect Cells
HGFR/c-Met Protein, Cynomolgus, Recombinant (His)
TMPK-00499
Species: Cynomolgus
Expression System: HEK293
CD43 Protein, Rat, Recombinant (hFc)
TMPY-03824
Species: Rat
Expression System: HEK293
SHP-1 Protein, Mouse, Recombinant (aa 207-597, His & GST)
TMPY-03296
Species: Mouse
Expression System: Baculovirus-Insect Cells
SEMA4D Protein, Human, Recombinant (aa 22-734, His)
TMPJ-00396
Species: Human
Expression System: Human Cells
CD43 Protein, Mouse, Recombinant (hFc)
TMPY-02435
Species: Mouse
Expression System: HEK293
CD122/IL2RB Protein, Human, Recombinant (aa 27-239, His & Avi), Biotinylated
TMPJ-00326
Species: Human
Expression System: Human Cells
BLNK Protein, Human, Recombinant (His)
TMPY-02191
Species: Human
Expression System: HEK293
Wnt3a Protein, Human, Recombinant (His)
TMPH-01961
Species: Human
Expression System: E. coli
Tetraspanin-7/TSPAN7 Protein, Human, Recombinant (E. coli, His)
TMPH-02192
Species: Human
Expression System: E. coli
PRKN Protein, Mouse, Recombinant (GST)
TMPH-02631
Species: Mouse
Expression System: E. coli
HER2/ERBB2 Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPJ-00776
Species: Human
Expression System: Human Cells
CD19 Protein, Rhesus macaque, Recombinant (hFc)
TMPJ-00329
Species: Rhesus macaque
Expression System: Human Cells
CDC37 Protein, Human, Recombinant (GST)
TMPY-01715
Species: Human
Expression System: Baculovirus-Insect Cells
HER2/ERBB2 Protein, Human, Recombinant (aa 23-652, hFc)
TMPJ-00777
Species: Human
Expression System: Human Cells
CDC37 Protein, Mouse, Recombinant (His & GST)
TMPY-03534
Species: Mouse
Expression System: Baculovirus-Insect Cells
SLAMF6 Protein, Mouse, Recombinant (His)
TMPY-01809
Species: Mouse
Expression System: HEK293
SLAMF6 Protein, Human, Recombinant (hFc)
TMPY-03766
Species: Human
Expression System: HEK293
Cat No. Product Name
L1610 FDA-Approved Kinase Inhibitor Library

280 compounds
Targetmol’s FDA-Approved Kinase Inhibitor Library contains 280 marketed drugs with proven kinase inhibitory activity. These kinases include Insulin/IGF Receptors、PI 3-Kinase、CaM Kinase II、JAK、PKA、CDK、JNK、PKC、CKI II、MAPK、...
L1600 Kinase Inhibitor Library

2230 compounds
A unique collection of 2230 kinase inhibitors for high throughput screening and high content screening for drug discovery in kinase related diseases;
TargetMol