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Results for "

Src

" in TargetMol Product Catalog
  • Inhibitor Products
    219
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    TargetMol | composition
pp60 c-src (521-533) (phosphorylated) acetate
TP2137L
pp60 c-src (521-533) (phosphorylated) acetate is a regulator of focal adhesion formation and cell spreading. pp60 c-src (521-533) (phosphorylated) acetate also regulates cell motility and is a key component in the signaling pathway triggered by the motogenic hyaluronan receptor RHAMM.
  • $127
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RR-src acetate
TP2289L2986315-28-8
RR-src acetate is a synthetic peptide derived from the amino acid sequence surrounding the phosphorylation site in pp60src.
  • $148
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SRC-1 (686-700)
T81106394658-24-3
SRC-1 (686-700) is a bioactive peptide encompassing amino acids 686 to 700, which include the second LXXLL motif from NR box II of steroid receptor coactivator (SRC1). These coactivator proteins facilitate transcription by ligand-dependent interaction with nuclear receptors.
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P60v-src(137-157)
T81577131023-24-0
P60v-src(137-157) is a synthetic peptide that serves as an inhibitor of the tyrosine kinase activity of p60 v-src, with an IC50 value of 7.5 μM [1] [2].
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pp60 c-src (521-533) (phosphorylated)
TP2137149299-77-4
Peptide corresponding to the pp60c-src carboxy terminal regulatory domain; phosphorylated at Tyr527. Binds to pp60c-src and pp60v-src at the SH2 domain, suppressing their tyrosine kinase activity and transforming potential.
  • $452
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p60c-src substrate II, phosphorylated
T81578284660-72-6
Phosphorylated p60c-src substrate II is a pentapeptide and a phosphorylated polypeptide form of p60c-src substrate II. Phosphorylation is a critical post-translational modification (post-translationmodification) vital for biological regulatory processes [1].
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pp60 (v-SRC) Autophosphorylation Site, Phosphorylated
T39185176042-83-4
pp60 (v-SRC) Autophosphorylation Site, Phosphorylated is a phosphorylated peptide derived from an EGFR substrate. It serves as a valuable tool for quantifying phosphorylated substrates in screening EGFR Kinase inhibitors.
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RR-src
TP228981156-93-6
Tyrosine kinase substrate peptide
  • $288
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p60c-src substrate II
T76391168781-78-0
P60c-src substrate II is a potent pentapeptide substrate for the tyrosine kinase pp60c-src [1].
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Src Optimal Peptide Substrate
T39149168202-45-7
Src Optimal Peptide Substrate, a highly specific substrate of Src, serves as a reliable indicator of Src activity. It enables accurate assessment of Src kinase function.
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Osteogenic Growth Peptide (10-14) acetate
T37603L
Osteogenic Growth Peptide (10-14) acetate (Osteogenic Growth Peptide) is a Src inhibitor and an effective mitogen and stimulator of osteogenesis and hematopoiesis. Osteogenic Growth Peptide (10-14) acetate is responsible for the binding to the OGP receptor and activates an intracell
  • $227
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EPQpYEEIPIYL
T38965147612-86-0
EPQpYEEIPIYL, a phosphopeptide, is a ligand for the Src homology 2 (SH2) domain. It activates members of the Src family, such as Lck, Hck, and Fyn, through the binding interaction with SH2 domains.
  • $1,160
4-6 weeks
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Caffeic acid-pYEEIE
TP2053507471-72-9
Phosphopeptide ligand for the src SH2 domain (IC50 = 42 nM); displays 30-fold higher affinity than N-acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu (Ac-pYEEIE,).
  • $628
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Secretin, canine
TP1610110786-77-1
Secretin is an endocrine hormone that stimulates the secretion of bicarbonate-rich pancreatic fluids. Canine secretin can regulates gastric chief cell function and paracellular permeability in canine gastric monolayers by a Src kinase-dependent pathway.
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Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH
TP2085159439-02-8
Phosphopeptide ligand for the src SH2 domain (IC50 = 1 μM). Blocks src interactions with EGFR and FAK.
  • $207
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Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA
T75841
Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA (compound 1) serves as a high-affinity pentapeptide that binds to the src SH2 domain with an IC 50 value of approximately 1 µM. Additionally, it acts as an inhibitor of src SH3-SH2: phosphoprotein interactions [1].
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N-Acetyl-O-phosphono-Tyr-Glu Dipentylamide
TP2084190078-50-3
Phosphopeptide; binds to the src SH2 domain.
  • $207
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Tyrosine Kinase Peptide 1
T39178173691-86-6
Tyrosine Kinase Peptide 1 is a control substrate peptide for c-Src assay.
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ND1-YL2
T41146
ND1-YL2 is a peptide-based PROTAC®Degrader of steroid receptor co-activator 1 (SRC-1; also known as nuclear receptor coactivator 1, NCOA1). ND1-YL2 is composed of a stapled peptide that binds SRC-1 (YL2) joined by a linker to a tetrapeptide that binds UBR box domains. Upon ternary complex formation, SRC-1 is polyubiquitinated and subsequently degraded via the N-degron pathway. This Degrader induces dose-dependent degradation of SRC-1 in the MDA-MB-231 triple negative breast cancer cell line (DC50 = 10 μM), and binds to the PAS-B domain of SRC-1 (Ki = 320 nM). ND1-YL2 inhibits MDA-MB-231 cell migrationin vitro, and suppresses metastasis of MDA-MB-231 cellsin vivo.
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