Search Result

Search Results for "src"

Targets

Libraries

FDA-Approved Kinase Inhibitor Library Kinase Inhibitor Library

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Compounds

Cat No.	Product Name
T3593	Src Inhibitor 1	Src Kinase Inhibitor 1,Src-l1	Src
	Src Inhibitor 1 是一种选择性的、高效的、ATP-竞争性的双位点 Src 酪氨酸激酶抑制剂，能够抑制 Src (IC50:44 nM) 和 Lck (IC50:88 nM)。		Src
TP2289L	RR-src acetate	RR-src acetate(81156-93-6 Free base)	Others
	RR-src acetate 是一种合成肽，来源于 pp60src 中磷酸化位点周围的氨基酸序列。		Others
T13000	Src Inhibitor 3		Others , Src
	Src Inhibitor 3 是一种有效的 c-terminal Src 激酶抑制剂（CSK HTRF 中 IC50 <3 nM，Caliper 中 IC50 <4 nM）。 Src Inhibitor 3 增加由 T 细胞受体信号传导诱...		Others , Src
TP2137L	Pp60 c-src (521-533) (phosphorylated) acetate		Others
	pp60 c-src (521-533) (phosphorylated) acetate 是粘着斑形成和细胞扩散的调节剂。它还调节细胞运动，是由促运动透明质酸受体 RHAMM 触发的信号通路中的关键成分。		Others
T39185	Pp60 (v-SRC) Autophosphorylation Site, Phosphorylated	pp60 (v-SRC) Autophosphorylation Site, Phosphorylated
	pp60 (v-SRC) Autophosphorylation Site, Phosphorylated is a phosphorylated peptide derived from an EGFR substrate. It ser...
T39149	Src Optimal Peptide Substrate
	Src Optimal Peptide Substrate, a highly specific substrate of Src, serves as a reliable indicator of Src activity. It en...
TP2289	RR-src		Others
	Tyrosine kinase substrate peptide		Others
T76391	P60c-src substrate II
	p60c-src substrate II 是酪氨酸激酶pp60c-src 的高效五肽底物。
T11745	KB SRC 4		Others
	KB SRC 4 has antitumor activity. KB SRC 4 is a potent, and highly selective c-Src inhibitor, with a Ki of 44 nM and a Kd...		Others
T13062	T338C Src-IN-2		Others
	T338C Src-IN-2 is a potent mutant inhibitor of c-Src T338C kinase(IC50 of 317 nM). T338C Src-IN-2 also inhibits T338C/V3...		Others
T1811	WH-4-023	KIN001-112,Dual LCK/SRC inhibitor,KIN112	Src
	WH-4-023 是选择性Lck 和Src 抑制剂，它们的 IC50 分别为 2 nM、6 nM，对p38α 和 KDR 作用效果稍弱。		Src
T13061	T338C Src-IN-1		Others
	T338C Src-IN-1 is a potent mutant-Src T338C inhibitor(T338C,IC50=111 nM relative to WT c-Src (10-fold increase)).		Others
TP2137	Pp60 c-src (521-533) (phosphorylated)
	Peptide corresponding to the pp60c-src carboxy terminal regulatory domain; phosphorylated at Tyr527. Binds to pp60c-src ...
T38439	DC-Srci-6649
	DC-Srci-6649 is a potent and selective inhibitor of c-Src kinase, effectively blocking its phosphorylation and stabilizi...
T8499	ECF506		Src
	eCF506 是一种高效的、口服具有活力的非受体酪氨酸激酶Src 抑制剂，其IC50<0.5 nM。		Src
TQ0132	A 419259 trihydrochloride	RK 20449 trihydrochloride	Src
	A 419259 trihydrochloride 是一种 Src 家族激酶抑制剂，能够抑制 Src (IC50:9 nM)、Lck (IC50:3 nM)、Lyn (IC50:3 nM)。		Src
T3063	PD173955	PD-173955,PD 173955	Bcr-Abl , Apoptosis , Src
	PD173955是一种Src 激酶家族选择性抑制剂，对Src、Yes 和Abl 激酶IC50值约为22nM，对 FGFRα 的效力较低，对InsR 和PKC 无活性。		Bcr-Abl , Apoptosis , Src
T0152	Bosutinib	SKI-606,伯舒替尼	Bcr-Abl , Src , Autophagy
	Bosutinib 是一种合成的喹诺酮衍生物和双激酶抑制剂，靶向 Abl 和 Src 激酶的 IC50分别为 1 nM 和 1.2 nM。		Bcr-Abl , Src , Autophagy
T15675	Tirbanibulin Mesylate	KX2-391 Mesylate,KX01 Mesylate	Src , Microtubule Associated
	Tirbanibulin Mesylate 是一种 Src 抑制剂，靶向 Src 的肽底物位点。在肿瘤细胞中，GI50值为 9-60 nM。		Src , Microtubule Associated
T6345	Tirbanibulin	KX2-391,KX-01	Src , Microtubule Associated
	KX2-391 是一种高度选择性的 Src 激酶抑制，靶向 Src 的多肽底物结合位点，对多种癌症有疗效。		Src , Microtubule Associated