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Anti-RB Monoclonal Antibody (5B616)
(Synonyms: RB1, RB, pRb, pp110, p105-Rb, OSRC) Copy Product Info
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Synonyms: RB1, RB, pRb, pp110, p105-Rb, OSRC
Catalog No. TMAT-0582 Copy Product Info
🥰Excellent
Anti-RB Monoclonal Antibody (5B616) is a Mouse antibody targeting RB. Anti-RB Monoclonal Antibody (5B616) can be used in IHC.
Anti-RB Monoclonal Antibody
(5B616)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 µL | Inquiry | 7-10 days | 7-10 days | |
| 50 µL | Inquiry | 7-10 days | 7-10 days | |
| 100 µL | Inquiry | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-RB Monoclonal Antibody (5B616) is a Mouse antibody targeting RB. Anti-RB Monoclonal Antibody (5B616) can be used in IHC. |
| Synonyms | RB1, RB, pRb, pp110, p105-Rb, OSRC |
| Ig Type | IgG1 |
| Clone | 5B616 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | The Rb protein regulates differentiation, apoptosis, and cell cycle control by coordinating the cell cycle at G1-S with transcriptional machinery. During G1, cyclin D-dependent kinase-mediated phosphorylation of Rb at Ser-795 marks the conversion of Rb from a transcriptionally repressive, hypophosphorylated state to an inactive, phosphorylated state, which may be sustained through mitosis by differential phosphorylation of up to 16 putative serine or threonine residues. Pediatric cancer retinoblastoma and the formation of other human tumors can be attributed to mutations in the retinoblastoma tumor suppressor gene(Rb). |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human RB expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | RB1 |
| Gene ID | |
| Protein Name | Retinoblastoma-associated protein |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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