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Anti-RB1 Monoclonal Antibody (2J779)
(Synonyms: RB, pRb, pp110, p105-Rb, OSRC) Copy Product Info
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Synonyms: RB, pRb, pp110, p105-Rb, OSRC
Catalog No. TMAT-0712 Copy Product Info
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Anti-RB1 Monoclonal Antibody (2J779) is a Mouse antibody targeting RB1. Anti-RB1 Monoclonal Antibody (2J779) can be used in WB,IF,FCM.
Anti-RB1 Monoclonal Antibody
(2J779)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-RB1 Monoclonal Antibody (2J779) is a Mouse antibody targeting RB1. Anti-RB1 Monoclonal Antibody (2J779) can be used in WB,IF,FCM. |
| Synonyms | RB, pRb, pp110, p105-Rb, OSRC |
| Ig Type | IgG1 |
| Clone | 2J779 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human RB1 (AA: 745-928) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | RB1 |
| Gene ID | |
| Protein Name | Retinoblastoma-associated protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 106.2 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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