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Search Result

Search Results for "raf"

Targets

Raf

Libraries

Anti-Pancreatic Cancer Compound Library FDA-Approved Kinase Inhibitor Library Kinase Inhibitor Library DGK Inhibitors Library
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Compounds

Cat No. Product Name
T4167 Raf inhibitor 1 dihydrochloride B-Raf inhibitor 1 dihydrochloride Raf
B-Raf inhibitor 1 dihydrochloride 是 Raf 激酶抑制剂，对 B-RafWT、B-RafV600E 和 C-Raf 的Ki 分别为 1、1 和 0.3 nM。
T1845 B-Raf IN 1 Raf
B-Raf IN 1 是选择性B-Raf 抑制剂， IC50为 24 nM。
T40284 B-Raf IN 2 Raf
B-Raf IN 2, derived from the patented WO2021116055A1, compound Ia, is a highly effective and specific inhibitor of BRAF....
T4194 Raf inhibitor 2 CID 25014542,CID-25014542,CID25014542 Raf
Raf inhibitor 2 是新型 Raf 激酶抑制剂，IC50小于 1.0 μM，可用于癌症研究。详细信息来源于 EP1003721B1 专利中的化合物 32。
T67862 B-Raf IN 13 Raf
B-Raf IN 13 是一种 有效的B-Raf 抑制剂，具有抗癌活性。B-Raf IN 13 在 BRAF V600E 酶测定实验中 IC50 为 3.55 nM。
T2074 Raf inhibitor 1 B-Raf inhibitor 1 Raf
Raf inhibitor 1是Raf 激酶抑制剂，对B-RafWT、B-RafV600E 和 C-Raf 的Ki 分别为 1、1 和 0.3 nM。
T63365 RAF-IN-1
RAF-IN-1 是 b/cRAF 的有效抑制剂，能够作用于 cRAF (IC50: 3.8 nM)、bRAFwt (IC50: 36 nM)，bRAFV600E (IC50: 29.4 nM)，能够抑制携带 bRAFV600E 突变的 A...
T64116 B-Raf IN 5
B-Raf IN 5 是蛋白激酶 B-Raf 的有效抑制剂 (IC50: 2.0 nM)。B-Raf IN 5 可抵抗快速代谢，切不结合二级靶点 PXR。B-Raf IN 5 对癌症疾病表现出研究潜力。
T60727 B-Raf IN 8
B-Raf IN 8 (compound 7g) 是 B-Raf 的有效抑制剂 (IC50 = 70.65 nM)。B-Raf IN 8 显示出抗肿瘤活性，其对肝细胞癌 (HEPG-2)、结肠癌 (HCT-116)，乳腺癌 (MCF-7) ...
T60933 B-Raf IN 7
B-Raf IN 7 (compound 6a) 是 B-Raf 的有效抑制剂，IC50值为 110.23 nM。B-Raf IN 7 对结肠癌细胞(HCT-116)、乳腺癌细胞 (MCF-7)、肝癌细胞 (HEPG-2)、人宫颈癌细胞 (...
T61935 B-Raf IN 9
B-Raf IN 9 (compound 8b) 是有效的B-Raf 抑制剂（IC50= 24.79 nM）。B-Raf IN 9 将细胞周期阻滞于 G2/M 期，诱导凋亡。B-Raf IN 9 对人前列腺癌 PC-3 细胞表现出较强的抗肿...
T63855 B-Raf IN 6
B-Raf IN 6 是蛋白激酶 B-Raf 的有效抑制剂 (IC50: 1.7 nM)。B-Raf IN 6 不结合二级靶点 PXR，并可抵抗快速代谢。B-Raf IN 6 对癌症疾病表现出研究潜力。
T63333 B-Raf IN 10
B-Raf IN 10 是 BRAF 抑制剂 (IC50: 50-100 nM)，表现出抗肿瘤作用。
T36642 RAS/RAS-RAF-IN-1
RAS/RAS-RAF-IN-1 is a potent RAS and RAS-RAF inhibitor. RAS/RAS-RAF-IN-1 has a KD of 5.0 μμ-15 μμ for cyclophilin A (CYP...
T63386 Pan-RAF kinase inhibitor 1
Pan-RAF kinase inhibitor 1 是 Pan-RAF 激酶对有效抑制剂， 能够抑制 RAF 激酶，调节 MAPK 信号传导，进而影响 RAS 突变肿瘤细胞的增殖。 Pan-RAF kinase inhibitor 1 对...
T72605 C-RAF kinase-IN-1
C-RAFkinase-IN-1 是一种有效的C-RAF 激酶抑制剂，IC50为 0.193 μM。C-RAFkinase-IN-1 是一种喹啉衍生物。C-RAFkinase-IN-1 具有研究癌症疾病的潜力。
T12685 RAF mutant-IN-1 Others
RAF mutant-IN-1 is an inhibitor of RAF kinase(IC50 values of 21 nM, 30 nM and 392 nM for C-RAF 340D/Y341D, B-RAFV600E an...
T12556 PROTAC B-Raf degrader 1 Raf
PROTAC B-Raf degrader 1 is a proteolysis targeting chimera (PROTAC) for the degradation of B-Raf,PROTAC B-Raf degrader 1...
T3711 RAF709 Raf
RAF709 是RAF 抑制剂，抑制BRAF 和CRAF，IC50分别为 0.4 和 0.5 nM，具有抗肿瘤活性。
T6296 RAF265 CHIR-265 Apoptosis , Raf , VEGFR , Autophagy
RAF265 是一种 RAF/VEGFR2抑制剂。
Raf inhibitor 1 dihydrochloride
T4167
synonym: B-Raf inhibitor 1 dihydrochloride
Target:
B-Raf IN 1
T1845
synonym:
Target:
B-Raf IN 2
T40284
synonym:
Target:
Raf inhibitor 2
T4194
synonym: CID 25014542,CID-25014542,CID25014542
Target:
B-Raf IN 13
T67862
synonym:
Target:
Raf inhibitor 1
T2074
synonym: B-Raf inhibitor 1
Target:
RAF-IN-1
T63365
synonym:
Target:
B-Raf IN 5
T64116
synonym:
Target:
B-Raf IN 8
T60727
synonym:
Target:
B-Raf IN 7
T60933
synonym:
Target:
B-Raf IN 9
T61935
synonym:
Target:
B-Raf IN 6
T63855
synonym:
Target:
B-Raf IN 10
T63333
synonym:
Target:
RAS/RAS-RAF-IN-1
T36642
synonym:
Target:
Pan-RAF kinase inhibitor 1
T63386
synonym:
Target:
C-RAF kinase-IN-1
T72605
synonym:
Target:
RAF mutant-IN-1
T12685
synonym:
Target:
PROTAC B-Raf degrader 1
T12556
synonym:
Target:
RAF709
T3711
synonym:
Target:
RAF265
T6296
synonym: CHIR-265
Target:
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