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Anti-BRAF Antibody (7G224)
😃Good
Catalog No. TMAB-03199
Anti-BRAF Antibody (7G224) is a Mouse antibody targeting BRAF. Anti-BRAF Antibody (7G224) can be used in WB,IHC-P,IHC-Fr,IF,ELISA,IP.
Anti-BRAF Antibody (7G224)
Anti-BRAF Antibody (7G224)
😃Good
Catalog No. TMAB-03199
Anti-BRAF Antibody (7G224) is a Mouse antibody targeting BRAF. Anti-BRAF Antibody (7G224) can be used in WB,IHC-P,IHC-Fr,IF,ELISA,IP.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-BRAF Antibody (7G224) is a Mouse antibody targeting BRAF. Anti-BRAF Antibody (7G224) can be used in WB,IHC-P,IHC-Fr,IF,ELISA,IP. |
| Ig Type | IgG2a, κ |
| Clone | 7G224 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200; ELISA: 1:30-3000; IP: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Nucleus. Cytoplasm. Cell membrane. |
| Tissue Specificity | Brain and testis. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes. A pseudogene of this gene has been identified on the X chromosome. [provided by RefSeq, Aug 2017] |
| Immunogen | Recombinant Protein: human B-Raf protein |
| Antigen Species | Human |
| Gene Name | BRAF |
| Gene ID | |
| Protein Name | Serine/threonine-protein kinase B-raf |
| Uniprot ID | |
| Function | Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. |
| Molecular Weight | Theoretical: 84 (human)/89 (mouse, rat) kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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