o4 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T19837	O4	O 4,O-4
	O4 is a novel stabilizer of amyloid- fibrils. O4 used for accelerating the formation of end-stage mature fibrils.
T67275	Bis[2-(1-isoquinolinyl-N)phenyl-C](2,4-pentanedionato-O2,O4)iridium(III)
	Bis[2-(1-isoquinolinyl-N)phenyl-C](2,4-pentanedionato-O2,O4)iridium(III) is a useful organic compound for research related to life sciences. The catalog number is T67275 and the CAS number is 435294-03-4.
T22416	RO495	CS-2667	Tyrosine Kinases , JAK
	RO495 (CS-2667), a potent inhibitor of TYK2, inhibits TYK2 with IC50 of 1.5nM as tested in cell-based pharmacological assays		Tyrosine Kinases , JAK
T2437	O4I2	O-4I2,O4I2	OCT
	O4I2 is an effective Oct3/4 inducer in various human cell lines including human fibroblasts.		OCT
TP2481	FOXO4-DRI acetate		Others
	FOXO4-DRI acetate is a bioactive chemical.		Others
T77578	CHBO4		MAO , ROS
	CHBO4 is an hMAO-B inhibitor that is potent, reversible, competitive and selective.The IC50 value of CHBO4 against hMAO-B in the CHBO assay was 0.031 μM, and the Ki value was 0.010 ± 0.005 μM.CHBO4 reduces cellular damag...		MAO , ROS
T5412	RO4987655	CH4987655,RG7167	MEK
	RO4987655 (RG7167) is an orally active and highly selective MEK inhibitor (IC50: 5.2 nM for MEK1/MEK2).		MEK
T2439	O4I1		OCT
	O4I1 is an effective Oct3/4 inducer.		OCT
T6274	RO4929097	RG-4733	Beta Amyloid , Gamma-secretase
	RO4929097 (RG-4733), a γ secretase inhibitor (IC50: 4 nM), inhibits cellular processing of Aβ40 and Notch (EC50: 14/5 nM).		Beta Amyloid , Gamma-secretase
T74186	PROTAC-O4I2		Apoptosis , PROTACs
	PROTAC-O4I2, a PROTAC ligand targeting splicing factor 3B1 (SF3B1), induced FLAG-SF3B1 degradation in K562 cells with an IC50 value of 0.244 μM. PROTAC-O4I2 induced apoptosis in K562 WT cells.		Apoptosis , PROTACs
T82654	Cy3-PEG3-TCO4
	Cy3-PEG3-TCO4, a dye derivative with three polyethylene glycol (PEG) units linked to Cyanine 3 (Cy3), possesses a trans-cyclooctene (TCO) group capable of undergoing the inverse electron demand Diels-Alder reaction (iEDD...
T66985	TAK 438 xC4H4O4
	TAK 438 xC4H4O4 is a useful organic compound for research related to life sciences and the catalog number is T66985.
T76563	FOXO4-DRI
	FOXO4-DRI, a cell-permeable peptide antagonist, inhibits the interaction between FOXO4 and p53. It functions as a senolytic peptide, promoting apoptosis in senescent cells [1].
T83495	[D-Pro4,D-Trp7,9] Substance P (4-11)
	[D-Pro4,D-Trp7,9] Substance P (4-11) acts as a potent antagonist to Substance P, significantly reducing plasma aldosterone (ALDO) concentrations[1].
T82656	Cy3-PEG2-TCO4
	Cy3-PEG2-TCO4, a Cyanine 3 (Cy3) dye derivative with two polyethylene glycol (PEG) units, utilizes its TCO moiety to engage in inverse electron demand Diels-Alder reactions (iEDDA) with Tetrazine-functionalized molecules...
T83496	[D-Pro4,D-Trp7,9,10] Substance P (4-11)
	[D-Pro4,D-Trp7,9,10] Substance P (4-11) serves as a potent antagonist of the tachykinin family of neuropeptides [1].
T82943	AtPCO4-IN-1
	AtPCO4-IN-1 is a selective AtPCO4 inhibitor, exhibiting an IC50 value of 264.4 μM [1].
T76406	[D-Pro4,D-Trp7,9,Nle11] Substance P (4-11)
	[D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) is a potent neurokinin NK1 antagonist that effectively inhibits the actions of gold-protein-substance P (GPSP) and substance P (SP), demonstrating its efficacy in neutralizing t...
T28600	Ro4491533	Ro 4491533,Ro-4491533
	Ro4491533 is a potent and selective negative allosteric modulator for group II of the metabotropic glutamate receptors (mGluR2/3).
T28601	RO4988546	RO-4988546,RO 4988546
	RO4988546 is a potent negative allosteric modulator of mGlu₂/₃.