microtubule — TargetMol Chemicals

Cat No.	Product Name	Targets
T71584	Microtubule Inhibitor 185322
	Microtubule inhibitor 185322 is an inhibitor of microtubule assembly, inducung mitotic arrest and apoptosis of MM cells.
T12034	Microtubule inhibitor 1	Others
	Microtubule inhibitor 1 is an antitumor agent with microtubule polymerization inhibitory activity(IC50 = 9-16 nM, in cancer cells).	Others
T62448	Microtubule inhibitor 6
	Microtubule inhibitor 6 (compound 17o) is a potent microtubule inhibitor. microtubule inhibitor 6 exhibited cytotoxicity against NCI-H460 cells, BxPC-3 cells, and HT-29 cells, with IC50 values of 14.0, 6.6, and 7.0 nM, r...
T61749	Microtubule inhibitor 2
	Microtubule inhibitor 2 is a highly potent and selective microtubule inhibitor, which is orally active. It induces cell death via ferroptosis, and exhibits notable antitumor activity [1].
T61765	Microtubule inhibitor 5
	Microtubule inhibitor 5 (compound 17f) is a highly potent cytotoxic agent that inhibits microtubule function. It exhibits a substantial cytotoxic effect on NCI-H460 cells, with an IC50 value of 154.5 nM. Moreover, this c...
TP1420	Microtubule-associated protein tau (26-44)
	Microtubule-associated protein tau (26-44) is a synthetic peptide with an amino group conjugated to glutamine and a carboxyl group conjugated to lysine.
T62642	Microtubule inhibitor 4
	Microtubule inhibitor 4 (compound 2) is a potent inhibitor of microtubule and inhibits microtubule protein polymerization, HT-29 cells (IC50: 2.1 nM) exhibited cytotoxicity.
T62867	Microtubule inhibitor 3
	Compounds 17o (IC50: 14.0 nM, NCI-H460) and 17p (IC50: 2.9 nM, NCI-H460) with furan moieties showed potent cytotoxic effects at the nanomolar level against various human cancer cell lines.
T62639	Microtubule inhibitor 7
	Compounds 17o (IC50= 14.0 nM, NCI-H460) and 17p (IC50= 2.9 nM, NCI-H460) with furan moieties show potent nanomolar levels of cytotoxic activity against various human cancer cell lines.
T74166	Microtubule destabilizing agent-1
	Microtubule destabilizing agent-1 (Compound 12b), a hydroxamic acid-based microtubule destabilizing agent (MDA), exhibits potent antitumor activity, favorable metabolic stability, and high bioavailability, making it a pr...
T79508	Microtubule stabilizing agent-1
	Compound 3l, a paclitaxel derivative known as Microtubule Stabilizing Agent-1, effectively enhances tubulin polymerization and demonstrates antitumor efficacy [1].
T36850	Curvulin	Microtubule Associated
	Curvulin is the active metabolite isolated from Paraphoma sp. VIZR 1.46. Curvularin inhibits iNOS expression and microtubule assembly.	Microtubule Associated
T14349	Auristatin F	Microtubule Associated
	Auristatin F is an effective inhibitor of microtubule and vascular damaging agent. Auristatin F can be used in antibody-drug conjugates.	Microtubule Associated
T15236	Entasobulin	Microtubule Associated
	Entasobulin is an inhibitor of β-tubulin polymerization. It has a potential anticancer activity.	Microtubule Associated
T60026	KIF18A-IN-2	Microtubule Associated
	KIF18A-IN-2 is an inhibitor of mitotic kinesin Kif18A with IC50 of 28 nM and can be used in studies about chromosomal instability-associated vulnerabilities.	Microtubule Associated
TN2190	Scoulerine	Apoptosis , Beta-Secretase , BACE , Parasite
	Scoulerine is an inhibitor of ß-site amyloid precursor protein cleaving enzyme 1(BACE1). Scoulerine a potent antimitotic compound that inhibits proliferation, arrests cell cycle, and induces apoptosis in cancer cells.	Apoptosis , Beta-Secretase , BACE , Parasite
T9504	MAP4343	Microtubule Associated
	Map4343 is a 3-methyl ether derivative of pregnenolone. Map4343 binds to microtubule associated protein 2 (MAP2) in vitro and stimulates tubulin polymerization, resulting in enhanced neurite extension and protection of n...	Microtubule Associated
T8188	Podophyllotoxone	Others , Microtubule Associated
	Podophyllotoxinone, a natural compound found in Dysosma versipellis, shows inhibitory activity against L1210 leukemia and KB cells in vitro.	Others , Microtubule Associated
T22661	CHM-1	Apoptosis , Others , Microtubule Associated
	CHM-1 is an inducer of apoptosis, and displays potent antitumor ability in human hepatocellular carcinoma by activation of Cdc2 kinase activity. CHM-1 inhibits tubulin polymerization in vitro and in vivo.	Apoptosis , Others , Microtubule Associated
T39994	Sovilnesib	Microtubule Associated
	Sovilnesib is a kinesin-like protein KIF18A inhibitor. Sovilnesib can be used for the cancer research.	Microtubule Associated