Advanced

Advanced glycation end products (AGEs) are stable compounds formed through non-enzymatic reactions between reducing sugars and proteins, lipids, or nucleic acids. AGEs are often utilized as targets for evaluating the inhibitory effects of anti-glycation compounds.

5β,6β-Epoxycholestanol is an oxidative metabolite of cholesterol produced through radical and non-radical oxidation at the 5,6-double bond. It induces the release of lactate dehydrogenase (LDH) and apoptosis in differentiated macrophage U937 cells. This compound has been identified in human fatty streaks and advanced atherosclerotic lesions but is absent in normal aortic tissue.

Silyl-ether based ROMP monomer iPrSi is a biochemical reagent utilized in the synthesis of advanced polymer materials for biomedical applications, such as drug delivery carriers and hydrogels.