MMP

Matrix metallopeptidases (MMPs), also known as matrix metalloproteinases or matrixins, are metalloproteinases that are calcium-dependent zinc-containing endopeptidases; other family members are adamalysins, serralysins, and astacins. The MMPs belong to a larger family of proteases known as the metzincin superfamily.

Cat. No.	Product name	CAS No.	Purity
T15055	DB04760	544678-85-5	98%
T15055	DB04760 is a highly selective, non-zinc-chelating inhibitor of MMP-13 (IC50: 8 nM). DB04760 obviously decreases paclitaxel neurotoxicity and has anticancer acti...
T30531L	BMS-561392 Formic acid	T30531L	98%
T30531L	BMS-561392 Formic acid is a selective inhibitor of TACE and reduces TNFalpha levels.
T28145	ND-322 HCl	1333379-23-9	98%
T28145	ND-322 HCl is a selective inhibitor of MT1-MMP and MMP2 and reduces in vitro melanoma cell growth, migration and invasion.
T28394	PG-116800	291533-11-4	98%
T28394	PG-116800 is a matrix metalloproteinase (MMP) inhibitor. PG-116800 can be used in studies about the treatment of osteoarthritis.
T60071	PF 00356231	766536-21-4	98%
T60071	PF 00356231 is a selectivity inhibitor MMP-12 and can be used in studies about the treatment of emphysema and chronic obstructive pulmonary disease (COPD).
T4122	TAPI-1 trifluoroacetate (163847-77-6(free base))	T4122	98%
T4122	TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.
T60083	MMP-12 Inhibitor	1258003-93-8	98%
T60083	MMP-12 Inhibitor is a selective inhibitor of MMP-12 with IC50s of 2, 160, 320, and 22.3 nM for human, mouse, rat, and sheep MMP-12.
T4082	Astragaloside	17429-69-5	98%
T4082	Astragaloside, one of the main active ingredients in Astragalus membranaceus.
TP1446	Histatin 5 (TFA)(115966-68-2,free)	TP1446	98%
TP1446	Histatin 5 TFA inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μM, respectively.
T3426	Bacoside A	11028-00-5	98%
T3426	Bacoside A has a possible anticancer activity that could be inducing cell cycle arrest and apoptosis through Notch pathway in GBM in vitro. It exerts cytoprotect...
TN4394	Kobophenol A	124027-58-3	98%
TN4394	Kobophenol A has antimicrobial, and anti-inflammatory activities, it might be a candidate for treatment of inflammatory bone diseases relevant to osteoblast cell...
TN1881	Lucidenic acid C	95311-96-9	98%
TN1881	Lucidenic acid C has anti-invasive effect, it shows significant inhibitory effects on PMA-induced MMP-9 activity and invasion of HepG(2 )cells.
TN3587	Capillarisin	56365-38-9	98%
TN3587	Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cell...
T10597	BR351	960113-85-3	98%
T10597	BR351 is a brain penetrant MMP inhibitor (IC50s: 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13).
TN4429	Leucodin	17946-87-1	98%
TN4429	Leucodin shows high anti-hypercholesterolemic potential. Leucodin may have anti-allergic activity, it shows a potent inhibitory activity upon the beta-hexosamini...
TN4263	Isoangustone A	129280-34-8	98%
TN4263	Isoangustone A has antitumor activity, it can induce G1 cycle arrest in DU145 human prostate and 4T1 murine mammary cancer cells, it inhibits cell proliferation ...
TN1867	Licoricidin	30508-27-1	98%
TN1867	Licoricidin, is a potent anti-metastatic agent, which can markedly inhibit the metastatic and invasive capacity of malignant prostate cancer cells.
TN1376	α-Solanine	20562-02-1	98%
TN1376	Alpha-Solanine alters antioxidative enzyme activities and MDA and PCO concentrations and GST activity in fat body and midgut.
TN3691	Communic acid	2761-77-5	98%
TN3691	Communic acid has antibacterial activity, including against mycobacterial. trans-Communic acid has potential to be utilized as anti-wrinkling agents and cosmetic...
T69685	AGPS-IN-2i	2316782-88-2	98%
T69685	AGPS-IN-2i is a potent and high-affinity inhibitor of alkylglycerol phosphate synthase that controls ether lipid utilization and metabolism in cells, reduces eth...