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MMP

Matrix metallopeptidases (MMPs), also known as matrix metalloproteinases or matrixins, are metalloproteinases that are calcium-dependent zinc-containing endopeptidases; other family members are adamalysins, serralysins, and astacins. The MMPs belong to a larger family of proteases known as the metzincin superfamily.
Cat. No. Product name CAS No. Purity Chemical Structure
T15055 DB04760 544678-85-5 98%
DB04760 is a highly selective, non-zinc-chelating inhibitor of MMP-13 (IC50: 8 nM). DB04760 obviously decreases paclitaxel neurotoxicity and has anticancer acti...
T30531L BMS-561392 Formic acid T30531L 98%
BMS-561392 Formic acid is a selective inhibitor of TACE and reduces TNFalpha levels.
T28145 ND-322 HCl 1333379-23-9 98%
ND-322 HCl is a selective inhibitor of MT1-MMP and MMP2 and reduces in vitro melanoma cell growth, migration and invasion.
T28394 PG-116800 291533-11-4 98%
PG-116800 is a matrix metalloproteinase (MMP) inhibitor. PG-116800 can be used in studies about the treatment of osteoarthritis.
T60071 PF 00356231 766536-21-4 98%
PF 00356231 is a selectivity inhibitor MMP-12 and can be used in studies about the treatment of emphysema and chronic obstructive pulmonary disease (COPD).
T4122 TAPI-1 trifluoroacetate (163847-77-6(free base)) T4122 98%
TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.
T60083 MMP-12 Inhibitor 1258003-93-8 98%
MMP-12 Inhibitor is a selective inhibitor of MMP-12 with IC50s of 2, 160, 320, and 22.3 nM for human, mouse, rat, and sheep MMP-12.
T4082 Astragaloside 17429-69-5 98%
Astragaloside, one of the main active ingredients in Astragalus membranaceus.
TP1446 Histatin 5 (TFA)(115966-68-2,free) TP1446 98%
Histatin 5 TFA inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μM, respectively.
T3426 Bacoside A 11028-00-5 98%
Bacoside A has a possible anticancer activity that could be inducing cell cycle arrest and apoptosis through Notch pathway in GBM in vitro. It exerts cytoprotect...
TN4394 Kobophenol A 124027-58-3 98%
Kobophenol A has antimicrobial, and anti-inflammatory activities, it might be a candidate for treatment of inflammatory bone diseases relevant to osteoblast cell...
TN1881 Lucidenic acid C 95311-96-9 98%
Lucidenic acid C has anti-invasive effect, it shows significant inhibitory effects on PMA-induced MMP-9 activity and invasion of HepG(2 )cells.
TN3587 Capillarisin 56365-38-9 98%
Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cell...
T10597 BR351 960113-85-3 98%
BR351 is a brain penetrant MMP inhibitor (IC50s: 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13).
TN4429 Leucodin 17946-87-1 98%
Leucodin shows high anti-hypercholesterolemic potential. Leucodin may have anti-allergic activity, it shows a potent inhibitory activity upon the beta-hexosamini...
TN4263 Isoangustone A 129280-34-8 98%
Isoangustone A has antitumor activity, it can induce G1 cycle arrest in DU145 human prostate and 4T1 murine mammary cancer cells, it inhibits cell proliferation ...
TN1867 Licoricidin 30508-27-1 98%
Licoricidin, is a potent anti-metastatic agent, which can markedly inhibit the metastatic and invasive capacity of malignant prostate cancer cells.
TN1376 α-Solanine 20562-02-1 98%
Alpha-Solanine alters antioxidative enzyme activities and MDA and PCO concentrations and GST activity in fat body and midgut.
TN3691 Communic acid 2761-77-5 98%
Communic acid has antibacterial activity, including against mycobacterial. trans-Communic acid has potential to be utilized as anti-wrinkling agents and cosmetic...
T69685 AGPS-IN-2i 2316782-88-2 98%
AGPS-IN-2i is a potent and high-affinity inhibitor of alkylglycerol phosphate synthase that controls ether lipid utilization and metabolism in cells, reduces eth...
DB04760
T15055
DB04760 is a highly selective, non-zinc-chelating inhibitor of MMP-13 (IC50: 8 nM). DB04760 obviously decreases paclitaxel neurotoxicity and has anticancer acti...
BMS-561392 Formic acid
T30531L
BMS-561392 Formic acid is a selective inhibitor of TACE and reduces TNFalpha levels.
ND-322 HCl
T28145
ND-322 HCl is a selective inhibitor of MT1-MMP and MMP2 and reduces in vitro melanoma cell growth, migration and invasion.
PG-116800
T28394
PG-116800 is a matrix metalloproteinase (MMP) inhibitor. PG-116800 can be used in studies about the treatment of osteoarthritis.
PF 00356231
T60071
PF 00356231 is a selectivity inhibitor MMP-12 and can be used in studies about the treatment of emphysema and chronic obstructive pulmonary disease (COPD).
TAPI-1 trifluoroacetate (163847-77-6(free base))
T4122
TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.
MMP-12 Inhibitor
T60083
MMP-12 Inhibitor is a selective inhibitor of MMP-12 with IC50s of 2, 160, 320, and 22.3 nM for human, mouse, rat, and sheep MMP-12.
Astragaloside
T4082
Astragaloside, one of the main active ingredients in Astragalus membranaceus.
Histatin 5 (TFA)(115966-68-2,free)
TP1446
Histatin 5 TFA inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μM, respectively.
Bacoside A
T3426
Bacoside A has a possible anticancer activity that could be inducing cell cycle arrest and apoptosis through Notch pathway in GBM in vitro. It exerts cytoprotect...
Kobophenol A
TN4394
Kobophenol A has antimicrobial, and anti-inflammatory activities, it might be a candidate for treatment of inflammatory bone diseases relevant to osteoblast cell...
Lucidenic acid C
TN1881
Lucidenic acid C has anti-invasive effect, it shows significant inhibitory effects on PMA-induced MMP-9 activity and invasion of HepG(2 )cells.
Capillarisin
TN3587
Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cell...
BR351
T10597
BR351 is a brain penetrant MMP inhibitor (IC50s: 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13).
Leucodin
TN4429
Leucodin shows high anti-hypercholesterolemic potential. Leucodin may have anti-allergic activity, it shows a potent inhibitory activity upon the beta-hexosamini...
Isoangustone A
TN4263
Isoangustone A has antitumor activity, it can induce G1 cycle arrest in DU145 human prostate and 4T1 murine mammary cancer cells, it inhibits cell proliferation ...
Licoricidin
TN1867
Licoricidin, is a potent anti-metastatic agent, which can markedly inhibit the metastatic and invasive capacity of malignant prostate cancer cells.
α-Solanine
TN1376
Alpha-Solanine alters antioxidative enzyme activities and MDA and PCO concentrations and GST activity in fat body and midgut.
Communic acid
TN3691
Communic acid has antibacterial activity, including against mycobacterial. trans-Communic acid has potential to be utilized as anti-wrinkling agents and cosmetic...
AGPS-IN-2i
T69685
AGPS-IN-2i is a potent and high-affinity inhibitor of alkylglycerol phosphate synthase that controls ether lipid utilization and metabolism in cells, reduces eth...
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