T60071 |
PF 00356231
|
766536-21-4
|
99.35%
|
|
PF 00356231 is a selectivity inhibitor MMP-12 and can be used in studies about the treatment of emphysema and chronic obstructive pulmonary disease (COPD).
|
T4122 |
TAPI-1 trifluoroacetate (163847-77-6(free base))
|
T4122
|
98.06%
|
|
TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.
|
T60083 |
MMP-12 Inhibitor
|
1258003-93-8
|
97.51%
|
|
MMP-12 Inhibitor is a selective inhibitor of MMP-12 with IC50s of 2, 160, 320, and 22.3 nM for human, mouse, rat, and sheep MMP-12.
|
T3090 |
Abietic Acid
|
514-10-3
|
92.6%
|
|
Abietic Acid (Sylvic acid) is the primary component of resin acid isolated from rosin.
|
TP1446 |
Histatin 5 (TFA)(115966-68-2,free)
|
TP1446
|
100%
|
|
Histatin 5 (TFA)(115966-68-2,free) (Histatin 5 (TFA)) inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μM,...
|
TN4394 |
Kobophenol A
|
124027-58-3
|
98%
|
|
Kobophenol A has antimicrobial, and anti-inflammatory activities, it might be a candidate for treatment of inflammatory bone diseases relevant to osteoblast cell...
|
TN1881 |
Lucidenic acid C
|
95311-96-9
|
98%
|
|
Lucidenic acid C has anti-invasive effect, it shows significant inhibitory effects on PMA-induced MMP-9 activity and invasion of HepG(2 )cells.
|
T78117 |
FN-439 TFA
|
|
98%
|
|
FN-439 TFA is a selective inhibitor of collagenase-1, exhibiting inhibition with an IC50 of 1 μM, and is utilized in cancer and inflammation research [1] [2].
|
T78436 |
Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2
|
720710-69-0
|
98%
|
|
Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 (FS-6) is a quenched, fluorescent MMP peptide substrate designed for the real-time quantification of MMP enzymatic a...
|
T78774 |
MMP13-IN-4
|
514855-02-8
|
98%
|
|
MMP13-IN-4 (compound 13) is a potent, selective MMP-13 inhibitor with an IC50 of 14.6 μM, implicated in the pathology of osteoarthritis (OA) [1].
|
T78775 |
MMP13-IN-5
|
|
98%
|
|
MMP13-IN-5 (compound 13m) is a potent, selective MMP-2/MMP-13 inhibitor with IC50 values of 3.6 μM for MMP-2 and 14.6 μM for MMP-13, implicated in the pathology ...
|
T80217 |
BT1718
|
2227366-66-5
|
98%
|
|
BT1718 is a bicyclic peptide conjugate that targets MT1-MMP, a protease overexpressed in various advanced solid tumors such as triple-negative breast cancer (TNB...
|
T80242 |
TNO211
|
193475-71-7
|
98%
|
|
TNO211 is a bioactive peptide that functions as a highly soluble fluorogenic substrate for select Matrix Metalloproteinases (MMPs)—specifically MMP-2, 8, 12, 13,...
|
T80654 |
3,3′-Bisdemethylpinoresinol
|
340167-81-9
|
98%
|
|
3,3′-Bisdemethylpinoresinol, a natural lignin derivative, exhibits MMP-1 inhibitory activity in UVA-irradiated human dermal fibroblasts and can be isolated from ...
|
T81778 |
MMP-7-IN-3
|
2865097-58-9
|
98%
|
|
MMP-7-IN-3 is a potent, selective MMP-7 inhibitor that effectively suppresses the progression of kidney fibrosis in a mouse model with unilateral ureteral obstru...
|
T83168 |
Aderamastat
|
877176-23-3
|
98%
|
|
Aderamastat (FP-025) is an orally active inhibitor of matrix metalloproteinase 12 (MMP-12), utilized in the research of conditions such as asthma, chronic obstru...
|
TN3587 |
Capillarisin
|
56365-38-9
|
98%
|
|
Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cell...
|
T10597 |
BR351
|
960113-85-3
|
98%
|
|
BR351 is a brain penetrant MMP inhibitor (IC50s: 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13).
|
TN4429 |
Leucodin
|
17946-87-1
|
98%
|
|
Leucodin shows high anti-hypercholesterolemic potential. Leucodin may have anti-allergic activity, it shows a potent inhibitory activity upon the beta-hexosamini...
|
TN4263 |
Isoangustone A
|
129280-34-8
|
98%
|
|
Isoangustone A has antitumor activity, it can induce G1 cycle arrest in DU145 human prostate and 4T1 murine mammary cancer cells, it inhibits cell proliferation ...
|