T15055 |
DB04760
|
544678-85-5
|
98%
|
|
DB04760 is a highly selective, non-zinc-chelating inhibitor of MMP-13 (IC50: 8 nM). DB04760 obviously decreases paclitaxel neurotoxicity and has anticancer acti...
|
T30531L |
BMS-561392 Formic acid
|
T30531L
|
98%
|
|
BMS-561392 Formic acid is a selective inhibitor of TACE and reduces TNFalpha levels.
|
T28145 |
ND-322 HCl
|
1333379-23-9
|
98%
|
|
ND-322 HCl is a selective inhibitor of MT1-MMP and MMP2 and reduces in vitro melanoma cell growth, migration and invasion.
|
T28394 |
PG-116800
|
291533-11-4
|
98%
|
|
PG-116800 is a matrix metalloproteinase (MMP) inhibitor. PG-116800 can be used in studies about the treatment of osteoarthritis.
|
T60071 |
PF 00356231
|
766536-21-4
|
98%
|
|
PF 00356231 is a selectivity inhibitor MMP-12 and can be used in studies about the treatment of emphysema and chronic obstructive pulmonary disease (COPD).
|
T4122 |
TAPI-1 trifluoroacetate (163847-77-6(free base))
|
T4122
|
98%
|
|
TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.
|
T60083 |
MMP-12 Inhibitor
|
1258003-93-8
|
98%
|
|
MMP-12 Inhibitor is a selective inhibitor of MMP-12 with IC50s of 2, 160, 320, and 22.3 nM for human, mouse, rat, and sheep MMP-12.
|
T4082 |
Astragaloside
|
17429-69-5
|
98%
|
|
Astragaloside, one of the main active ingredients in Astragalus membranaceus.
|
TP1446 |
Histatin 5 (TFA)(115966-68-2,free)
|
TP1446
|
98%
|
|
Histatin 5 TFA inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μM, respectively.
|
T3426 |
Bacoside A
|
11028-00-5
|
98%
|
|
Bacoside A has a possible anticancer activity that could be inducing cell cycle arrest and apoptosis through Notch pathway in GBM in vitro. It exerts cytoprotect...
|
TN4394 |
Kobophenol A
|
124027-58-3
|
98%
|
|
Kobophenol A has antimicrobial, and anti-inflammatory activities, it might be a candidate for treatment of inflammatory bone diseases relevant to osteoblast cell...
|
TN1881 |
Lucidenic acid C
|
95311-96-9
|
98%
|
|
Lucidenic acid C has anti-invasive effect, it shows significant inhibitory effects on PMA-induced MMP-9 activity and invasion of HepG(2 )cells.
|
TN3587 |
Capillarisin
|
56365-38-9
|
98%
|
|
Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cell...
|
T10597 |
BR351
|
960113-85-3
|
98%
|
|
BR351 is a brain penetrant MMP inhibitor (IC50s: 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13).
|
TN4429 |
Leucodin
|
17946-87-1
|
98%
|
|
Leucodin shows high anti-hypercholesterolemic potential. Leucodin may have anti-allergic activity, it shows a potent inhibitory activity upon the beta-hexosamini...
|
TN4263 |
Isoangustone A
|
129280-34-8
|
98%
|
|
Isoangustone A has antitumor activity, it can induce G1 cycle arrest in DU145 human prostate and 4T1 murine mammary cancer cells, it inhibits cell proliferation ...
|
TN1867 |
Licoricidin
|
30508-27-1
|
98%
|
|
Licoricidin, is a potent anti-metastatic agent, which can markedly inhibit the metastatic and invasive capacity of malignant prostate cancer cells.
|
TN1376 |
α-Solanine
|
20562-02-1
|
98%
|
|
Alpha-Solanine alters antioxidative enzyme activities and MDA and PCO concentrations and GST activity in fat body and midgut.
|
TN3691 |
Communic acid
|
2761-77-5
|
98%
|
|
Communic acid has antibacterial activity, including against mycobacterial. trans-Communic acid has potential to be utilized as anti-wrinkling agents and cosmetic...
|
T69685 |
AGPS-IN-2i
|
2316782-88-2
|
98%
|
|
AGPS-IN-2i is a potent and high-affinity inhibitor of alkylglycerol phosphate synthase that controls ether lipid utilization and metabolism in cells, reduces eth...
|