T16555 |
PNU-103017
|
166335-18-8
|
98%
|
|
PNU-103017 is an inhibitor of HIV protease.
|
TN3567 |
Calanolide E
|
142566-61-8
|
98%
|
|
Calanolide E2 has anti-HIV activity.
|
T60742 |
HIV-1 integrase inhibitor 8
|
1568-80-5
|
98%
|
|
HIV-1 integrase inhibitor 8 is a HIV-1 integrase inhibitor.
|
TN2284 |
Triptonine B
|
168009-85-6
|
98%
|
|
Triptonine B demonstrates potent anti-HIV activity with an EC(50) value of <0.10 microg/mL and an in vitro therapeutic index value of >1000.
|
T0742 |
Papaverine hydrochloride
|
61-25-6
|
98%
|
|
Papaverine hydrochloride can used in an effective manner in the management of renal colic pain in patients unresponsive to commonly used conventional agents. Pap...
|
T6589 |
MK-2048
|
869901-69-9
|
98%
|
|
MK-2048 is a potent inhibitor of integrase (IN) and INR263K with IC50 of 2.6 nM and 1.5 nM, respectively.
|
TN5011 |
Shizukaol B
|
142279-40-1
|
98%
|
|
Shizukaol B exerts anti-inflammatory effects in LPS-activated microglia partly by modulating JNK-AP-1 signaling pathway; it also shows significant anti-neuroinfl...
|
T12420L |
Pentosan Polysulfate Sodium (W/W 43%)
|
140207-93-8
|
98%
|
|
Pentosan Polysulfate Sodium is a potent and selective anti-HIV agent.with anti-inflammatory and pro-chondrogenic properties,and used for treatment of interstitia...
|
T16112 |
ML67-33
|
1443290-89-8
|
98%
|
|
ML67-33 rapidly and reversibly affects K2P2.1 (TREK-1) (EC50s: 36.3 μM and 9.7 μM in cell-free and HEK293 cells, respectively). ML67-33 is a selective activator ...
|
T6418 |
BMS-378806
|
357263-13-9
|
98%
|
|
BMS-378806 selectively inhibits the binding of HIV-1 gp120 to the CD4 receptor with EC50 of 0.85-26.5 nM in virus.
|
T10928 |
Cytochalasin A
|
14110-64-6
|
98%
|
|
Cytochalasin A is a cell-permeable fungal toxin and is an oxidized derivative of cytochalasin B. Cytochalasin A is an inhibitor of HIV-1 protease (IC50 = 3 μM), ...
|
TN3152 |
6-Acetonyldihydrochelerythrine
|
22864-92-2
|
98%
|
|
6-Acetonyldihydrochelerythrine exhibits significant antioxidant activities, it exhibits significant anti-HIV activity in H9 lymphocytes with EC50 and TI (Therape...
|
TN1708 |
Gomisin M2
|
82425-45-4
|
98%
|
|
Gomisin M2 is an anti-HIV agent.
|
T10658 |
CA inhibitor 1
|
2189684-45-3
|
98%
|
|
CA inhibitor 1 (GS-6207 analog) is a potent inhibitor of the HIV capsid.
|
TN2186 |
Schisantherin D
|
64917-82-4
|
98%
|
|
Schisantherin D shows good anti-HIV activity with the EC50 value of 0.5 micrograms/mL, and the therapeutic index (TI) value of 110.
|
T16829 |
(S)-BI-1001
|
957889-73-5
|
98%
|
|
(S)-BI-1001 is an active S-enantiomer of BI-1001. (S)-BI-1001 has antiviral potency against HIV-1 integrase (IC50: 28 nM, and EC50: 450 nM and a Kd: 4.7 μM).
|
T5S0983 |
Absinthin
|
1362-42-1
|
98%
|
|
1. Absinthiin is a weak HIV-1 protease inhibitor.
|
TN1866 |
Licoricesaponin G2
|
118441-84-2
|
98%
|
|
Licoricesaponin G2 has the anti-inflammatory effects as NF-κB inhibitors, it has anti-HIV activity via significantly interacted with R15K.
|
TN4585 |
Moronic acid
|
6713-27-5
|
98%
|
|
Moronic acid shows oral therapeutic efficacy in HSV-infected mice and possessed novel anti-HSV activity. It also shows significant anti-HIV activity (EC(50) 186)...
|
TN2839 |
2alpha,19alpha-Dihydroxy-3-oxo-urs-12-en-28-oic acid
|
176983-21-4
|
98%
|
|
2alpha,19alpha-Dihydroxy-3-oxo-urs-12-en-28-oic acid has anti-HIV activity. It shows an inhibitory effect on the activation of Epstein-Barr virus early antigen (...
|