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  • Inhibitors & Agonists
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Inosine
NSC 20262, INO 495
T043758-63-9
Inosine (NSC-20262) is a purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It has immunomodulatory, neuroprotective, and analgesic properties.
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Baicalein
5,6,7-Trihydroxyflavone
T2858491-67-8
Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor.
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Blumeatin
TN1002118024-26-3
Blumeatin has antioxidant properties, free radical scavenging activity,and has xanthine oxidase (XO) inhibitory activity.
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6-diazo-5-oxo-l-nor-leucine
L-6-Diazo-5-oxonorleucine, DON, Diazooxonorleucine
T8373157-03-9
6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine) is a glutaminase antagonist (Ki: 6 μM) and an antineoplastic antibiotic produced by an unidentified Streptomyces species from Peruvian soil.
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Doxorubicin hydrochloride
NSC 123127, Hydroxydaunorubicin hydrochloride, DOX hydrochloride, Adriamycin HCl
T102025316-40-9
Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I II (IC50=0.8 2.67 μM). Doxorubicin hydrochloride exhibits cytotoxicity and antitumor activity. Doxorubicin hydrochloride reduces the phosphorylation of AMPK and its downstream target protein acetyl coenzyme A carboxylase, and induces apoptosis and autophagy.
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5-Methoxy-5-oxopentanoic acid
mono-Methyl glutarate, METHYL HYDROGEN GLUTARATE
T47641501-27-5
Mono-Methyl glutarate is an endogenous metabolite i with anti-inflammatory and antioxidant activity.
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Fidaxomicin
Tiacumicin B, OPT-80, Clostomicin B1, PAR-101
T6194873857-62-6
Fidaxomicin (Tiacumicin B) is a semisynthetic macrolide antibiotic used to treat Clostridium difficile-associated diarrhea in adults. Fidaxomicin has minimal systemic absorption and has not been linked to serum enzyme elevations during therapy or to instances of clinically apparent, acute liver injury.
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(Z)-4-Amino-4-oxobut-2-enoic acid
Maleamic acid, Acrylic acid
T4905557-24-4
(Z)-4-Amino-4-oxobut-2-enoic acid (Maleamic acid) is a valuable compound for research applications.
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(R)-5-Oxopyrrolidine-2-carboxylic acid
D-Pyroglutamic acid, (R)-(+)-2-Pyrrolidone-5-carboxylic acid
T48144042-36-8
(R)-5-Oxopyrrolidine-2-carboxylic acid (D-Pyroglutamic acid) is a cyclic derivative of glutamic acid, physiologically present in mammalian tissues. It releases GABA from the cerebral cortex and exhibits anti-anxiety effects in a simple approach-avoidance conflict situation in rats. In clinical pharmacology experiments, it significantly shortens the plasma half-life of ethanol during acute intoxication.
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4-Methyl-2-oxopentanoic acid
α-KIC, 4-Methyl-2-oxovaleric acid, α-Ketoisocaproic acid
T5071816-66-0
4-Methyl-2-oxopentanoic acid is an abnormal metabolite, a neurotoxin and a metabolic toxin.
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D-Lyxose
D-(-)-Lyxose
T48961114-34-7
D-Lyxose (D-(-)-Lyxose) is used as a chiral building block.
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Doxofylline
Doxophylline
T048069975-86-6
Doxofylline (Doxophylline) is a methylxanthine derivative with the presence of a dioxolane group in position 7. As a drug used in the treatment of asthma, doxofylline has shown similar efficacy to theophylline but with significantly fewer side effects in animal and human studies.
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3-Ethoxy-3-oxopropanoic acid
Monoethyl malonic acid, Ethyl hydrogen malonate
T47731071-46-1
3-Ethoxy-3-oxopropanoic acid (Monoethyl malonic acid) belongs to the class of organic compounds known as dicarboxylic acids and derivatives. These are organic compounds containing exactly two carboxylic acid groups. 3-Ethoxy-3-oxopropanoic acid exists as a solid, soluble (in water), and a weakly acidic compound (based on its pKa). 3-Ethoxy-3-oxopropanoic acid has been primarily detected in blood. Within the cell, monoethyl malonic acid is primarily located in the cytoplasm.
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3-Methyl-2-oxobutanoic acid
2-Oxoisovaleric acid, alpha-Ketoisovaleric acid
T5232759-05-7
3-Methyl-2-oxobutanoic acid (2-Oxoisovaleric acid) is an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids. 3-Methyl-2-oxobutanoic acid is a neurotoxin, an acidogen, and a metabotoxin. A neurotoxin causes damage to nerve cells and nerve tissues. 3-Methyl-2-oxobutanoic acid is a keto-acid, which is a subclass of organic acids. Abnormally high levels of organic acids in the blood (organic acidemia), urine (organic aciduria), the brain, and other tissues lead to general metabolic acidosis.
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Oxoadipic acid
2-Oxoadipic acid
T49213184-35-8
Oxoadipic acid (2-Oxoadipic acid) is a key metabolite of the essential amino acids tryptophan and lysine.Important metabolite between the TCA cycle and lysine biosynthesis. Of interest for research on mitochondrial metabolite transporters.
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Xanthotoxol
8-Hydroxyfuranocoumarin, 8-Hydroxypsoralene, Psoralen, 8-Hydroxypsoralen
T4S16592009-24-7
Xanthotoxol (Psoralen) is a biologically active linear furocoumarin, shows strong pharmacological activities as anti-inflammatory, antioxidant, 5-HT antagonistic, and neuroprotective effects.
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Bardoxolone
RTA 401, CDDO
T2915218600-44-3
Bardoxolone (CDDO) is a synthetic oleanane triterpenoid that blocks the cellular synthesis of inducible nitric oxide synthase and inducible COX-2 in INF-γ-activated mouse macrophages with an IC50 value of 0.4 nM. By suppressing reactive oxygen and nitrogen species (ROS RNS) formation, it promotes the cellular control of ROS RNS levels that would lead to DNA damage associated with tumorigenesis. In various Y cell lines, Bardoxolone has been shown to specifically inhibit proliferation and induce apoptosis. Mechanism studies revealed that Bardoxolone is a ligand for peroxisome proliferator-activated receptor γ, and also that it induces genes regulated by Nrf2, including heme oxygenase-1 and eotaxin-1, which play a role in antioxidant response element signaling activity.
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Carbenoxolone
Carbenoxolone, Carbenoxolona, Bioral, Biogastrone
T77325697-56-3
Carbenoxolone (Biogastrone) is an inhibitor of 11β-HSD and gap junction connexin channels. Carbenoxolone inhibits macrophage migration into atria and prevents the development of fatty liver disease.
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16R-Hydroxy-3-oxolanosta7,9(11),24-trien-21-oic acid
16R-Hydroxy-3-oxolanosta7,9(11),24-trien-21-oic acid
T40962862109-64-6
16R-Hydroxy-3-oxolanosta7,9(11),24-trien-21-oic acid, a lanostanoid, is found in the basidiomycete Ganoderma applanatum from Sri Lanka.
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Myxopyroside
T124990345641-11-4
Myxopyroside is a useful organic compound for research related to life sciences. The catalog number is T124990 and the CAS number is 345641-11-4.
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3-oxoandrost-4-en-17-yl hexanoate
T131615
3-oxoandrost-4-en-17-yl hexanoate is a useful organic compound for research related to life sciences and the catalog number is T131615.
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3,11,15,23-Tetraoxo-27ξ-lanosta-8,16-dien-26-oic acid
T388921427189-02-3
3,11,15,23-Tetraoxo-27ξ-lanosta-8,16-dien-26-oic acid, a lanostane-type triterpenoid extracted from [Antrodia camphorate], is a chemical compound.
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4-(6-Methyl-4-oxohept-5-en-2-yl)cyclohex-2-en-1-one
TN2994170380-68-4
4-(6-Methyl-4-oxohept-5-en-2-yl)cyclohex-2-en-1-one is a natural product for research related to life sciences. The catalog number is TN2994 and the CAS number is 170380-68-4.
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8-Oxoeremophil-6-en-12-oic aicd
T126063
8-Oxoeremophil-6-en-12-oic aicd is a useful organic compound for research related to life sciences and the catalog number is T126063.
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