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  • Endogenous Metabolite
    (33)
  • Xanthine Oxidase
    (21)
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    (18)
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    (17)
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    (17)
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    (12)
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    (11)
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    (10)
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Results for "

xo

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    1142
    TargetMol | Inhibitors_Agonists
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    1
    TargetMol | Compound_Libraries
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    30
    TargetMol | Peptide_Products
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    TargetMol | Inhibitory_Antibodies
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    15
    TargetMol | Dye_Reagents
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    TargetMol | PROTAC
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    322
    TargetMol | Natural_Products
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    TargetMol | Recombinant_Protein
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    TargetMol | Isotope_Products
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    TargetMol | Antibody_Products
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    114
    TargetMol | Inhibitors_Agonists
Febuxostat
TMX 67, TEI 6720
T0773144060-53-7
Febuxostat (TEI 6720) is a xanthine oxidase inhibitor.
  • $32
In Stock
Size
QTY
Inosine
NSC 20262, INO 495
T043758-63-9
Inosine (NSC-20262), an endogenous purine nucleoside produced by the catabolism of adenosine, is an agonist of adenosine receptors A1R and A2AR. Inosine has anti-inflammatory, immunomodulatory, antinociceptive and neuroprotective effects.
  • $29
In Stock
Size
QTY
Allopurinol
Zyloric, Zyloprim, Lopurin
T0692315-30-0
Allopurinol (Zyloric) is a Xanthine Oxidase Inhibitor. The mechanism of action of allopurinol is as a Xanthine Oxidase Inhibitor.
  • $50
In Stock
Size
QTY
Baicalein
5,6,7-Trihydroxyflavone
T2858491-67-8
Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor.
  • $30
In Stock
Size
QTY
Pyrazoloadenine
4-Aminopyrazolo[3,4-d]pyrimidine
T93662380-63-4
Pyrazoloadenine (4-Aminopyrazolo[3,4-d]pyrimidine) is the inhibitor of human xanthine oxidase.
  • $29
In Stock
Size
QTY
N-Demethylricinine
4-Methoxy-2-oxo-1,2-dihydro-pyridine-3-carbonitrile
T136321642-98-8
N-Demethylricinine (4-Methoxy-2-oxo-1,2-dihydro-pyridine-3-carbonitrile) was reported as xanthine oxidase inhibitor.
  • $29
In Stock
Size
QTY
TargetMol | Inhibitor Sale
Oxypurinol
Oxipurinol
T16942465-59-0
Oxypurinol is a xanthine oxidase inhibitor. Oxipurinol is potentially used for the treatment of congestive heart failure.
  • $44
In Stock
Size
QTY
Xanthine oxidase
XOD, XO
T761049002-17-9
Xanthine oxidase (XO) is an enzyme involved in purine catabolism and conversion to uric acid, generating reactive oxygen species, used in the study of cardiovascular diseases.
  • $245
7-10 days
Size
QTY
Blumeatin
TN1002118024-26-3
Blumeatin has antioxidant properties, free radical scavenging activity,and has xanthine oxidase (XO) inhibitory activity.
  • $56
In Stock
Size
QTY
URAT1&XO inhibitor 3
T2001912089040-93-5
URAT1&XO Inhibitor 3 (compound 27) is an orally effective anti-gout agent targeting XO (IC50: 35 nM) and URAT1 (IC50: 31 nM). This compound exhibits favorable pharmacological and pharmacokinetic (PK) characteristics, as well as in vivo safety.
  • $2,720
3-6 months
Size
QTY
XO/COX/LOX-IN-1
T62350
XO COX LOX-IN-1 is a potent inhibitor of xanthine oxidase cyclooxygenase lipoxygenase XO COX LOX. XO COX LOX-IN-1 can be used in the study of inflammatory, cancer and metabolic diseases.
  • $1,520
10-14 weeks
Size
QTY
URAT1&XO inhibitor 1
T791752669726-78-5
URAT1&XO Inhibitor 1 (compound 29) serves as a dual inhibitor with IC50 values of approximately 10 μM for URAT1 and 1.01 μM for Xanthine Oxidase. It induces a hypouricemic effect in the potassium oxonate-induced hyperuricemic rat model and is utilized in research pertaining to hyperuricemia [1].
  • $1,520
8-10 weeks
Size
QTY
URAT1&XO inhibitor 2
T791771239488-96-0
Compound BDEO (URAT1&XO inhibitor 2) serves as a dual-action inhibitor targeting both xanthine oxidase (XO) and URAT1, demonstrating an IC50 value of 3.3 μM for XO inhibition. It effectively impedes uric acid uptake in HEK293 cells with URAT1 expression, evidenced by a Ki of 0.145 μM. In hyperuricemic mice models, the compound has been shown to reduce serum urate levels and uric acid excretion, indicating potential utility for hyperuricemia research [1].
  • $1,520
6-8 weeks
Size
QTY
Ruxolitinib
INCB018424, (R)-Ruxolitinib
T1829941678-49-5
Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective. Rixolitinib exhibits antitumor activity and induces autophagy and apoptosis.
  • $53
In Stock
Size
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TargetMol | Inhibitor Hot
Doxorubicin hydrochloride
NSC 123127, Hydroxydaunorubicin hydrochloride, DOX hydrochloride, Adriamycin HCl
T102025316-40-9
Doxorubicin hydrochloride is an anthracycline antibiotic with cytotoxic and antitumor activity. It is an effective inhibitor of human DNA topoisomerase I and II, with IC50 values of 0.8 μM and 2.67 μM, respectively. In addition to inhibiting DNA topoisomerases, it can reduce the phosphorylation of AMPK and its downstream target, acetyl-CoA carboxylase. Doxorubicin hydrochloride also induces apoptosis and autophagy. In animal studies, it is commonly used to induce models of acute renal failure, chronic kidney injury, and heart failure.
  • $34
In Stock
Size
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TargetMol | Inhibitor Hot
IAXO-102
T115981115270-63-7
IAXO-102 is a TLR4 antagonist that negatively regulates TLR4 signaling by inhibiting MAPK and p65 NF-κB phosphorylation, as well as the expression of TLR4-dependent proinflammatory proteins. It also prevents the development of experimental abdominal aortic aneurysm.
  • $89
In Stock
Size
QTY
TargetMol | Inhibitor Hot
Omaveloxolone
RTA-408
T69191474034-05-3
Omaveloxolone (RTA-408) (RTA-408) is a synthetic triterpenoid that activates the cytoprotective transcription factor Nrf2 and inhibits NF-κB signaling. Phase 2.
  • $38
In Stock
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TargetMol | Inhibitor Hot
6-Diazo-5-oxo-L-nor-Leucine
L-6-Diazo-5-oxonorleucine, DON, Diazooxonorleucine
T8373157-03-9
6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine) is a glutaminase antagonist (Ki: 6 μM) and an antineoplastic antibiotic produced by an unidentified Streptomyces species from Peruvian soil.
  • $40
In Stock
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TargetMol | Inhibitor Hot
Aldoxorubicin hydrochloride
Aldoxorubicin hydrochloride (1361644-26-9 Free base)
T11090L11361563-03-2In house
Aldoxorubicin hydrochloride is an albumin-binding prodrug of Doxorubicin, a DNA topoisomerase II inhibitor. Aldoxorubicin hydrochloride is released from albumin under acidic conditions. Aldoxorubicin hydrochloride exhibits potent antitumor activities in various cancer cell lines and in murine tumor models.
  • $57
In Stock
Size
QTY
Fiduxosin
ABT 980, A 185980.1
T11286208993-54-8In house
Fiduxosin is a selective and potent α1-adrenoceptor antagonist with inhibitory effects on α1a-adrenoceptor, α1b-adrenoceptor and α1d-adrenoceptor, with Ki values of 0.160 nM, 24.9 nM and 0.920 nM, respectively. Fiduxosin can be used for the treatment of benign prostatic hyperplasia.
  • $700
In Stock
Size
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Nexopamil racemate
(Rac)-Nexopamil
T12215116759-35-4In house
Nexopamil racemate((Rac)-Nexopamil) is a racemate of Nexopamil. The Nexopamil racemate has potential anti-asthmatic and anti-ulcer activity.
  • $700
In Stock
Size
QTY
Lometrexol
LY 264618, DDATHF
T15826106400-81-1In house
Lometrexol (LY 264618), an antipurine Antifolate, can inhibit the activity of glycinamide ribonucleotide formyltransferase (GARFT) but do not induce detectable levels of DNA strand breaks. Lometrexol can further inhibit de novo purine synthesis, causing abnormal cell proliferation and Apoptosis, even cell cycle arrest. Lometrexol has anticancer activity. Lometrexol also is a potent human Serine hydroxymethyltransferase1 2 (hSHMT1 2) inhibitor.
  • $81
In Stock
Size
QTY
Azepexole hydrochloride
4H-Oxazolo[4,5-d]azepin-2-amine, 6-ethyl-5,6,7,8-tetrahydro-, hydrochloride (1:1)
T21787L147663-20-5In house
Azepexole hydrochloride (4H-Oxazolo[4,5-d]azepin-2-amine, 6-ethyl-5,6,7,8-tetrahydro-, hydrochloride (1:1)) is a potent α2-Adrenoceptor agonist with anaesthetic effects.
  • $30
In Stock
Size
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Folitixorin calcium
CoFactor, ANX-510, ANX510, ANX 510
T25435133978-75-3In house
Folitixorin calcium is an antineoplastic enhancing agent.
  • $6,068
3-6 months
Size
QTY