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Fludioxonil
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Catalog No. T20905Cas No. 131341-86-1
Alias CGA 173506
Fludioxonil (CGA 173506), a phenylpyrrole fungicide, inhibits the growth of B. cinerea from strawberry and blackberry crops.
Fludioxonil
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Purity: 99.97%
Catalog No. T20905Alias CGA 173506Cas No. 131341-86-1
Fludioxonil (CGA 173506), a phenylpyrrole fungicide, inhibits the growth of B. cinerea from strawberry and blackberry crops.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 mg | $36 | In Stock | In Stock | |
| 50 mg | $52 | In Stock | In Stock | |
| 100 mg | $73 | - | In Stock | |
| 500 mg | $183 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information
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Purity:99.97%
Appearance:Solid
Color:Yellow
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Product Introduction
Fludioxonil AI Summary
Fludioxonil exhibits a broad spectrum of bioactivities. It demonstrates significant antifungal activity against various plant pathogens, including Saccharomyces cerevisiae, Botryotinia fuckeliana, Monilinia laxa, Rhizoctonia solani, and Ceratobasidium cereale, with varying degrees of effectiveness. Specifically, it shows strong efficacy in controlling Botryotinia fuckeliana in tomato seedlings and cucumber cotyledon, with activities up to 100% at certain concentrations. It also inhibits mycelial growth of Monilinia laxa and Rhizoctonia solani with low EC50 values, indicating potent antifungal properties.
Additionally, Fludioxonil affects multiple signaling pathways; it acts as an agonist for retinoid X receptor alpha, peroxisome proliferator-activated receptor gamma, the antioxidant response element signaling pathway, and rat pregnane X receptor signaling. Conversely, it serves as an antagonist for farnesoid X receptor, androgen receptor, peroxisome proliferator-activated receptor delta, vitamin D receptor, glucocorticoid receptor, aryl hydrocarbon receptor, and human pregnane X receptor signaling pathways.
In terms of photosynthesis inhibition, Fludioxonil reduces several photosynthetic metrics in Vitis vinifera cv. Pinot noir, including the Hill reaction activity, relative quantum yield of photosystem 2, and net photosynthetic rate, while increasing mitochondrial respiration in the light.
The compound also exhibits antiviral activity against SARS-CoV-2 in vitro, with an IC50 value greater than 20000 nM, suggesting moderate potency.
Collectively, these findings highlight the multifaceted bioactivity of Fludioxonil, making it a promising candidate for further investigation in agricultural and medical biotechnology applications..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Fludioxonil (CGA 173506), a phenylpyrrole fungicide, inhibits the growth of B. cinerea from strawberry and blackberry crops. |
| Synonyms | CGA 173506 |
| Molecular Weight | 248.18 |
| Formula | C12H6F2N2O2 |
| Cas No. | 131341-86-1 |
| Smiles | FC1(F)Oc2cccc(c2O1)-c1c[nH]cc1C#N |
| Relative Density. | 1.31g/cm3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 11 mg/mL (44.32 mM), Sonication is recommended.  | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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