Search Result

Search Results for " carcinoma "

Targets

Raf Ras

294

Compounds

123

Natural Products

307

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T1892	Kobe2602		Raf , Ras
	Kobe 2602 is an inhibitor of Ras that exhibits anticancer chemotherapeutic activities.		Raf , Ras
T26046	Razoxane		Topoisomerase
	Razoxane is used as an antimitotic agent with immunosuppressive properties.		Topoisomerase
T9693	TBAP-001		Raf
	TBAP-001 is a RAF kinase inhibitor, with an IC50 of 62 nM in BRAF V600E kinase assay and an IC50 of 18 nM in Cell-Based Phosho-ERK Assay.		Raf
T8344	CPTH2		Apoptosis , Histone Acetyltransferase
	CPTH2 is a histone acetyltransferase inhibitor modulating Gcn5 network.		Apoptosis , Histone Acetyltransferase
T6683	STF-62247	STF 62247	Estrogen/progestogen Receptor , Autophagy
	STF-62247 is TGN inhibitor with IC50 of 0.625 μM and 16 μM in RCC4 and RCC4/VHL cells, respectively.		Estrogen/progestogen Receptor , Autophagy
T26889	Borofalan(10B)	L-4-Boronophenylalanine	Others
	Borofalan(10B) (L-4-Boronophenylalanine) echibits antineoplastic effects. Borofalan can be used in studies on recurrent or locally advanced head and neck cancer.		Others
T23372	SMIFH2		Others
	SMIFH2 is formin homology 2 (FH2) domains inhibitor.		Others
T2282	RPI-1		Others , Phospholipase , c-Met/HGFR , c-RET
	RPI-1 is a competitive, potent ATP-dependent Ret kinase inhibitor.		Others , Phospholipase , c-Met/HGFR , c-RET
T8843	APS6-45		MAPK , Ras
	APS6-45 inhibits RAS/MAPK signaling and exhibits anti-tumor activity.		MAPK , Ras
T15371	Gardiquimod		TLR , HIV Protease
	Gardiquimod is a TLR7/8 agonist. When used at concentrations below 10 μM, Gardiquimod specifically activates TLR7. Gardiquimod could inhibit HIV-1 infection of macrophages and activated peripheral blood mononuclear cells...		TLR , HIV Protease
T5521	Bropirimine	U-54461	TLR
	Bropirimine (U-54461) (U-54461) is a biological response modifier that is thought to act through the induction of lymphokines.		TLR
T2676	PF-04217903		c-Met/HGFR
	MET Tyrosine Kinase Inhibitor PF-04217903 is an orally bioavailabe, small-molecule tyrosine kinase inhibitor with potential antineoplastic activity.		c-Met/HGFR
T1753	D-64131		Microtubule Associated
	D-64131 is a tubulin polymerization inhibitor with an IC50 value of 0.53 μM.		Microtubule Associated
T22661	CHM-1		Apoptosis , Others , Microtubule Associated
	CHM-1 is an inducer of apoptosis, and displays potent antitumor ability in human hepatocellular carcinoma by activation of Cdc2 kinase activity. CHM-1 inhibits tubulin polymerization in vitro and in vivo.		Apoptosis , Others , Microtubule Associated
T12695	RBN-2397		PARP
	RBN-2397 is a potent, selective and orally active accross species NAD+ competitive PARP7 inhibitor with IC50 less than 3 nM.		PARP
T6932	PD168393		Apoptosis , EGFR , FGFR , IGF-1R , PDGFR , PKC , Autophagy
	PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.		Apoptosis , EGFR , FGFR , IGF-1R , PDGFR , PKC , Autophagy
T28410	PHPS1	PHPS-1,PHPS 1	Phosphatase
	PHPS1 is an inhibitor of Shp2. PHPS1 efficiently inhibits activation of Erk1/2 by the leukemia-associated Shp2 mutant, Shp2-E76K, and blocks the anchorage-independent growth of a variety of human tumor cell lines.		Phosphatase
T15771	Lobaplatin	D-19466	DNA Alkylation
	Lobaplatin (D-19466) (D-19466) is a diastereometric mixture of platinum(II) complexe. Lobaplatin (D-19466) is a third-generation platinum anti-neoplastic agent which shows activity for a variety of tumour types and is a ...		DNA Alkylation
T6609	NMS-E973		HSP
	NMS-E973 is a potent and selective Hsp90 inhibitor with DC50 of <10 nM for Hsp90 binding, no activiy against a panel of 52 diverse protein kinases.		HSP
T9705	TL-895		BTK
	TL-895 is an ATP-competitive, and highly selective irreversible inhibitor of Bruton’s Tyrosine Kinase(BTK). TL-895 showed good potency with an IC50 of 1.5 nM and a Ki of 11.9 nM.		BTK
T15017	CU-T12-9		TLR
	CU-T12-9 is a potent TLR1/2 agonist(EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay). It acts by activating the NFkB pathway, upregulating proinflammatory cytokines, and enhancing TLR1 and TLR2 dimerization.CU-T12-9 activat...		TLR
TQ0157	EIPA	L593754,MH 12-43	Sodium Channel , TRP/TRPV Channel
	EIPA (L593754) (L593754, MH 12-43) is a TRPP3 channel inhibitor (IC50: 10.5 μM). It also inhibits Na+/H+-exchanger (NHE) and macropinocytosis.		Sodium Channel , TRP/TRPV Channel
T27730	KGP94	KGP-94,KGP 94	Cysteine Protease
	KGP94 is an inhibitor of cysteine protease Cathepsin L(CTSL).		Cysteine Protease
T12148	N-Desmethyltamoxifen hydrochloride		Estrogen Receptor/ERR , Endogenous Metabolite , PKC
	N-Desmethyltamoxifen hydrochloride is the major tamoxifen metabolite in humans.		Estrogen Receptor/ERR , Endogenous Metabolite , PKC
T7008	Vacquinol-1	Vacquinol 1	JNK
	Vacquinol-1 is an MKK4 activator, which rapidly and selectively induces glioma cell death.		JNK
T22830	GYY4137	GYY 4137 morpholine salt	Others
	GYY4137 (GYY 4137 morpholine salt) is a novel water-soluble and slow releasing H2S donor with vasodilator and antihypertensive activity. GYY4137 also exhibits anti-inflammatory and anticancer activity.		Others
T2455	PFK-015	PFK15,PFK 015	Glucokinase , Autophagy
	PFK-015 (PFK15) is an effective inhibitor of PFKFB3 (IC50: 110 nM) and inhibits PFKFB3 activity in Y cells (IC50: 20 nM).		Glucokinase , Autophagy
T9616	PD-1/PD-L1-IN-10		PD-1/PD-L1
	PD-1/PD-L1-IN-10 is an orally active PD-1/PD-L1 inhibitor (IC50 of 2.7 nM) with potent anticancer efficacy.		PD-1/PD-L1
T4570	Pipobroman	Vercyte,A-8103,Amedel	Others , DNA Alkylator/Crosslinker
	Pipobroman (Vercyte) is an anti-cancer drug that probably acts as an alkylating agent. Pipobroman has well documented clinical activity in polycythemia vera (PV) and essential thrombocythemia (ET). Pipobroman allows, wit...		Others , DNA Alkylator/Crosslinker
T1785	Palbociclib	PD 0332991	CDK
	Palbociclib (PD 0332991) is a CDK inhibitor that inhibits CDK4 and CDK6 (IC50=11/16 nM) and is orally active. Palbociclib has anti-tumorigenic activity and has investigational potential for use in ER-positive and HER2-ne...		CDK
T19147	5-ALA benzyl ester hydrochloride	Benzyl-ALA hydrochloride	Others , Endogenous Metabolite
	5-ALA benzyl ester hydrochloride (Benzyl-ALA hydrochloride) is a protoporphyrin precursor. 5-ALA benzyl ester hydrochloride is used as a photodetection agent. 5-ALA benzyl ester hydrochloride could induce protoporphyrin ...		Others , Endogenous Metabolite
T0314	Hexylresorcinol	4-Hexylresorcinol	Apoptosis , Tyrosinase , Antibacterial , Parasite
	Hexylresorcinol (4-Hexylresorcinol) is a substituted dihydroxybenzene used topically as an antiseptic for the treatment of minor skin infections.		Apoptosis , Tyrosinase , Antibacterial , Parasite
T6481	Droxinostat	NS 41080	Apoptosis , HDAC
	Droxinostat (NS 41080) is a selective inhibitor of HDAC, mostly for HDACs 6 and 8 with IC50 of 2.47 μM and 1.46 μM, greater than 8-fold selective against HDAC3 and no inhibition to HDAC1, 2, 4, 5, 7, 9, and 10.		Apoptosis , HDAC
T28475	Pyrazoloacridine	PD-115934,NSC 366140,NSC-366140,PD 115,934,PD 115934	Apoptosis , Topoisomerase
	Pyrazoloacridine (PD 115934) is a nucleic acid binding agent that inhibits the activity of topo I and II with an IC50 of 1.25 μM in K562 cells. Pyrazoloacridine shows anti-cancer activity.		Apoptosis , Topoisomerase
T21505	Suberoyl bis-hydroxamic acid	SBHA,Suberohydroxamic acid	Apoptosis , HDAC
	Suberoyl bis-hydroxamic acid (SBHA) is a Histone deacetylase (HDAC) inhibitor. HDAC is required for transcriptional modulation, cell cycle regulation and development. It is an enzyme that deacetylates lysine residues on ...		Apoptosis , HDAC
T2456	Tivozanib	AV-951,KRN951	VEGFR , PDGFR , Ephrin Receptor
	Tivozanib (KRN951) is an orally bioavailable inhibitor of vascular endothelial growth factor receptors (VEGFRs) 1, 2 and 3 with potential antiangiogenic and antineoplastic activities.		VEGFR , PDGFR , Ephrin Receptor
T1199	Mitotane	Mitotan,o,p'-DDD,NCI-C04933,2,4′-DDD	Apoptosis , AChR
	Mitotane (NCI-C04933) is a derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors a...		Apoptosis , AChR
T0334	Rosiglitazone	BRL49653	Ferroptosis , TRP/TRPV Channel , PPAR , Autophagy
	Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity. Rosiglitazone is also a hypoglycemic agent and a thiazolidinedione insulin sensitizer.		Ferroptosis , TRP/TRPV Channel , PPAR , Autophagy
T22443	Triglycidyl isocyanurate	Tris(2,3-epoxypropyl) Isocyanurate,Teroxirone,TGIC,TGI	Apoptosis
	Triglycidyl isocyanurate (Teroxirone) is a triazene triepoxide with antineoplastic and antiangiogenic activity. It inhibits growth of human non-small cell lung cancer cells by activating p53. Triglycidyl isocyanurate alk...		Apoptosis
T22450	Tyrphostin B44, (+) enantiomer		EGFR
	Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with IC50 of 0.86 μM and has less active than the (-) enantiomer.		EGFR
T1520	Aliskiren hemifumarate	CGP 60536,SPP 100,CGP60536B	RAAS , Autophagy
	Aliskiren hemifumarate (CGP60536B) is an orally active nonpeptide renin inhibitor with antihypertensive activity.		RAAS , Autophagy
T9945	MNK8	3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione	STAT
	MNK8 (3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione) is a potent STAT3 inhibitor that reduces the ability of STAT3 to bind to DNA and also has a good growth inhibition effect on liver cancer cells [1].		STAT
T6646	Rosiglitazone hydrochloride	BRL-49653 HCl,Rosiglitazone HCl	Ferroptosis , TRP/TRPV Channel , PPAR , Autophagy
	Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.		Ferroptosis , TRP/TRPV Channel , PPAR , Autophagy
T2008	LY294002	LY 294002,NSC 697286,SF 1101	Apoptosis , DNA-PK , Casein Kinase , PI3K , Autophagy
	LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM). LY294002 is also an inhibitor of DNA-PK (IC50=1.4 μM) and an inhibitor of CK2 (IC50=98 nM). LY294002 ...		Apoptosis , DNA-PK , Casein Kinase , PI3K , Autophagy
T3061	Lorlatinib	PF-6463922,PF-06463922,Loratinib	Apoptosis , Tyrosine Kinases , ROS , ALK , ROS Kinase
	Lorlatinib (PF-6463922) is an orally available, ATP-competitive inhibitor of the receptor tyrosine kinases, anaplastic lymphoma kinase (ALK) and C-ros oncogene 1 (Ros1), with potential antineoplastic activity.		Apoptosis , Tyrosine Kinases , ROS , ALK , ROS Kinase
T0134	Imiquimod	R 837,S-26308	SARS-CoV , TLR , Autophagy , HSV
	Imiquimod (R 837) is an immune response modifier that acts as a toll-like receptor 7 agonist.		SARS-CoV , TLR , Autophagy , HSV
T6239	Palbociclib monohydrochloride	PD 0332991 hydrochloride,Palbociclib hydrochloride,Palbociclib (PD-0332991) HCl	CDK
	Palbociclib monohydrochloride (PD 0332991 hydrochloride) is a selective inhibitor of CDK4/6 (IC50s: 11/16 nM). It exhibits no inhibition against a panel of 36 additional protein kinases.		CDK
T6240	Palbociclib Isethionate	Palbociclib (PD0332991) Isethionate,PD 0332991 isethionate	CDK
	Palbociclib Isethionate (PD 0332991 isethionate) is a selective inhibitor of CDK4/6 (IC50s: 11/16 nM). It exhibits no inhibition against a panel of 36 additional protein kinases.		CDK
T6690	T0901317		Apoptosis , FXR , Liver X Receptor , ROR
	T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively; it inhibits nuclear factor/κB (NF/κB).		Apoptosis , FXR , Liver X Receptor , ROR
T4079	LY-294002 hydrochloride	SF 1101,LY 294002,NSC 697286	PI3K
	LY-294002 hydrochloride (NSC 697286) is a synthetic molecule inhibitor of PI3Kα/δ/β (IC50: 0.5/0.57/0.97 μM, in cell-free assays); more stable than Wortmannin in solution, and also is a blocker of autophagosome formation...		PI3K

Compounds

Target: Topoisomerase

Target: Apoptosis, Histone Acetyltransferase

STF-62247

T6683

Synonym: STF 62247

Target: Estrogen/progestogen Receptor, Autophagy

Borofalan(10B)

T26889

Synonym: L-4-Boronophenylalanine

Target: Others, Phospholipase, c-Met/HGFR, c-RET

Target: TLR, HIV Protease

Target: Microtubule Associated

CHM-1

T22661

Synonym:

Target: Apoptosis, Others, Microtubule Associated

Target: Apoptosis, EGFR, FGFR, IGF-1R, PDGFR, PKC, Autophagy

PHPS1

T28410

Synonym: PHPS-1,PHPS 1

Target: DNA Alkylation

Synonym: L593754,MH 12-43

Target: Sodium Channel, TRP/TRPV Channel

KGP94

T27730

Synonym: KGP-94,KGP 94

Target: Cysteine Protease

N-Desmethyltamoxifen hydrochloride

T12148

Synonym:

Target: Estrogen Receptor/ERR, Endogenous Metabolite, PKC

Synonym: GYY 4137 morpholine salt

Target: Others

PFK-015

T2455

Synonym: PFK15,PFK 015

Target: Glucokinase, Autophagy

Synonym: Vercyte,A-8103,Amedel

Target: Others, DNA Alkylator/Crosslinker

5-ALA benzyl ester hydrochloride

T19147

Synonym: Benzyl-ALA hydrochloride

Target: Others, Endogenous Metabolite

Hexylresorcinol

T0314

Synonym: 4-Hexylresorcinol

Target: Apoptosis, Tyrosinase, Antibacterial, Parasite

Droxinostat

T6481

Synonym: NS 41080

Target: Apoptosis, HDAC

Pyrazoloacridine

T28475

Synonym: PD-115934,NSC 366140,NSC-366140,PD 115,934,PD 115934

Target: Apoptosis, Topoisomerase

Suberoyl bis-hydroxamic acid

T21505

Synonym: SBHA,Suberohydroxamic acid

Target: Apoptosis, HDAC

Tivozanib

T2456

Synonym: AV-951,KRN951

Target: VEGFR, PDGFR, Ephrin Receptor

Mitotane

T1199

Synonym: Mitotan,o,p'-DDD,NCI-C04933,2,4′-DDD

Target: Apoptosis, AChR

Rosiglitazone

T0334

Synonym: BRL49653

Target: Ferroptosis, TRP/TRPV Channel, PPAR, Autophagy

Triglycidyl isocyanurate

T22443

Synonym: Tris(2,3-epoxypropyl) Isocyanurate,Teroxirone,TGIC,TGI

Target: Apoptosis

Tyrphostin B44, (+) enantiomer

T22450

Synonym:

Target: EGFR

Aliskiren hemifumarate

T1520

Synonym: CGP 60536,SPP 100,CGP60536B

Target: RAAS, Autophagy

MNK8

T9945

Synonym: 3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione

Target: STAT

Rosiglitazone hydrochloride

T6646

Synonym: BRL-49653 HCl,Rosiglitazone HCl

Target: Ferroptosis, TRP/TRPV Channel, PPAR, Autophagy

LY294002

T2008

Synonym: LY 294002,NSC 697286,SF 1101

Target: Apoptosis, DNA-PK, Casein Kinase, PI3K, Autophagy

Lorlatinib

T3061

Synonym: PF-6463922,PF-06463922,Loratinib

Target: Apoptosis, Tyrosine Kinases, ROS, ALK, ROS Kinase

Imiquimod

T0134

Synonym: R 837,S-26308

Target: SARS-CoV, TLR, Autophagy, HSV

Palbociclib monohydrochloride

T6239

Synonym: PD 0332991 hydrochloride,Palbociclib hydrochloride,Palbociclib (PD-0332991) HCl

Target: CDK

Palbociclib Isethionate

T6240

Synonym: Palbociclib (PD0332991) Isethionate,PD 0332991 isethionate

Target: Apoptosis, FXR, Liver X Receptor, ROR

LY-294002 hydrochloride

T4079

Synonym: SF 1101,LY 294002,NSC 697286

Target: PI3K

Cat No.	Product Name	Synonyms	Targets
T3020	Sclareol		Apoptosis , Others
	Sclareol, a labdane-type diterpene isolated from clary sage (Salvia sclarea), exerts growth inhibition and cytotoxic activity against a variety of human Y cell lines.		Apoptosis , Others
T11363	Ganoderic acid F		Others
	Ganoderic acid F exhibits antitumor and antimetastatic activities through inhibition of angiogenesis and alteration of proteins involving cell proliferation and/or cell death, carcinogenesis, oxidative stress, calcium si...		Others
T3862	Irigenin		NF-κB , Integrin
	Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra Domain A domain. It can sensitize TRAIL-induced apoptosis by enha...		NF-κB , Integrin
T2786	Oxysophocarpine		Prostaglandin Receptor
	Oxysophocarpine is extracted from Sophra flavescens Ait.		Prostaglandin Receptor
T6670	Silymarin	Silybin B	SARS-CoV
	Silymarin (Silybin B) (Silybin B) is a polyphenolic flavonoid that extracts from the milk thistle or seeds of Silybum marianum. It is used in the prevention and treatment of liver diseases.		SARS-CoV
TN1968	N-Feruloyloctopamine	N-Feruloyloctopamine	p38 MAPK , Akt
	N-Feruloyloctopamine is a natural product.		p38 MAPK , Akt
T5S1133	Ganoderic acid D		Apoptosis , Sirtuin
	1. Ganoderic acid D is one of the major components in Ganoderma triterpenes. 2. Ganoderic acid D treatment for 48h inhibits the proliferation of HeLa human cervical carcinoma cells with an IC(5) value of 17.3 +/- .3 micr...		Apoptosis , Sirtuin
T13741	Isoviolanthin		Others
	Isoviolanthin reduces the migratory and invasive capacities of TGF-β1-treated HCC cells without cytotoxic effects on normal live cells and has potential as a therapeutic agent for the treatment of advanced-stage metastat...		Others
TN1019	Beta-mangostin	β-Mangostin	Apoptosis , Antibacterial , Parasite
	Beta-mangostin (β-Mangostin) is a xanthone compound with antibacterial and antimalarial activities. Beta-mangostin present in Cratoxylum arborescens and exhibits antimycobacterial activity against Mycobacterium tuberculo...		Apoptosis , Antibacterial , Parasite
T13475	β-Aminopropionitrile	3-Aminopropionitrile,BAPN	Others , Endogenous Metabolite
	β-Aminopropionitrile (3-Aminopropionitrile) is a selective inhibitor of lysyl oxidase.		Others , Endogenous Metabolite
T6485	Embelin	NSC 91874,Emberine,Embelic acid	Apoptosis , NF-κB , Lipoxygenase , IAP , Prostaglandin Receptor , Autophagy
	Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).
T7203	Oglufanide	L-Glutamyl-L-tryptophan,H-Glu-Trp-OH	VEGFR , HCV Protease , Endogenous Metabolite
	Oglufanide (H-Glu-Trp-OH) is a naturally occurring thymic immunomodulator,and inhibits vascular endothelial growth factor (VEGF).		VEGFR , HCV Protease , Endogenous Metabolite
T12581	Puerarin-4'-O-β-D-glucopyranoside	Puerarin4'-O-glucoside	Others
	Puerarin-4'-O-β-D-glucopyranoside (Puerarin4'-O-glucoside) is a natural product isolated from Pueraria lobata root having estrogenic activity and anti-proliferation in MCF-7 human breast carcinoma cells.		Others
T1511	Daunorubicin hydrochloride	Daunomycin HCl,RP-13057 Hydrochloride,Rubidomycin hydrochloride,Daunorubicin HCl,Daunomycin	Apoptosis , DNA/RNA Synthesis , Topoisomerase , Antibacterial , Antibiotic , Autophagy
	Daunorubicin hydrochloride (Rubidomycin hydrochloride), an anthracycline aminoglycoside antineoplastic, inhibits DNA replication and repair and RNA and protein synthesis.
T4S0797	Berberine	Berberin,Umbellatine	Reactive Oxygen Species , Topoisomerase , Endogenous Metabolite , Antibacterial , Antibiotic , Autophagy
	1. Berberine (Umbellatine) is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism. 2. Berberine may as a broad-spectrum anti-microbial medicine, a complementary therapeutic agent for HIV/AIDS. 3....
TN1757	Hypophyllanthin		Potassium Channel , Calcium Channel , P-gp
	Hypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice.		Potassium Channel , Calcium Channel , P-gp
TN1013	Cucurbitacin D		IL Receptor , JNK , STAT
	Cucurbitacin D has anticancer effects, it induces apoptosis through caspase-3 and phosphorylation of JNK in hepatocellular carcinoma cells.		IL Receptor , JNK , STAT
T7849	Norspermine		Others
	Norspermine is a polyamine analogue ,used in the treatment of non-small cell lung carcinoma and breast cancer.		Others
TN3548	Bulleyanin		Others
	Bulleyanin shows strong inhibition of mouse ehrlich ascites carcinoma (ECA), mouse sarcoma S-180, and mouse liver ascites.		Others
T1660	Silibinin	Silibinin A,Silybin,Silymarin I	Reactive Oxygen Species , Autophagy
	Silibinin (Silybin) is the major active constituent of silymarin, a standardized extract of the milk thistle seeds, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silicristin, silidianin an...		Reactive Oxygen Species , Autophagy
TN7217	4,6-Benzilidine-D-Glucose
	4,6-Benzilidine-D-Glucose is a clinical antitumor compound showing antitumor activity in rats with chemically induced hepatocellular carcinoma.
TN1405	Arnicolide D		Akt , Caspase , PI3K , STAT , mTOR
	Arnicolide D is a sesquiterpene lactone. Arnicolide D isolates from Centipeda minima. Arnicolide D modulates the cell cycle, activates the caspase signaling pathway and inhibits the PI3K/AKT/mTOR and STAT3 signaling path...		Akt , Caspase , PI3K , STAT , mTOR
T3051	Theaflavin-3-gallate	Theaflavine-3-Gallate	Others
	Theaflavin-3-gallate (Theaflavine-3-Gallate) can play a role in decreased intestinal cholesterol absorption via inhibition of micelle formation. Theaflavin-3-gallate has anticancer and apoptotic effects in non-small cell...		Others
T5040	Medroxyprogesterone		Estrogen/progestogen Receptor , Progesterone Receptor
	Medroxyprogesterone is used in the treatment of renal carcinoma. It is a synthetic progestational hormone used in veterinary practice as an estrus regulator.		Estrogen/progestogen Receptor , Progesterone Receptor
T4S1796	Heterophyllin B		PI3K
	Heterophyllin B effectively suppresses the adhesion and invasion of the human esophageal carcinoma cells by mediating the PI3K/AKT/β-catenin pathways and regulating the expression levels of adhesion- and invasion-associa...		PI3K
T1709	2'-Deoxyinosine	Guanine deoxyriboside,Deoxyinosine	Others , Endogenous Metabolite
	2'-Deoxyinosine (Guanine deoxyriboside) inhibits the growth of human colon-carcinoma cell lines and is associated with purine nucleoside phosphorylase (PNP) deficiency.		Others , Endogenous Metabolite
TN1644	Flavanomarein		Others
	Flavanomarein demonstrates potent antioxidative property, including free radical scavenging activity, inhibition of lipid peroxidation, as well as lipid-lowering effects in human HepG2 hepatocellular carcinoma cells trea...		Others
T6S1373	Casticin	Quercetagetin 3,6,7,4'-Tetramethyl Ether,Vitexicarpin	STAT
	1. Casticin (Vitexicarpin) can significantly reduce vascular inflammation, through inhibition of ROS-NF-κB pathway in vascular endothelial cells. 2. Casticin may become a potential leading drug in the therapy of prostate...		STAT
T2S1975	Ponicidin	Rubescensine B	Apoptosis , JAK , STAT
	Ponicidin (Rubescensine B) is a diterpenoid derived from Rabdosia rubescens. Ponicidin exhibits immunoregulatory, anti-inflammatory, anti-viral, and anti-cancer activity. Ponicidin induces apoptosis of gastric carcinoma ...		Apoptosis , JAK , STAT
T5746	Dictamine	Dictamnine,Dectamine	Apoptosis , Anti-infection , Antibacterial , Antifungal
	Dictamine (Dectamine) shows anticholinesterase, anti-inflammatory, mutagenic, and has antimicrobial activity against bacteria and fungi. It has the ability to exert cytotoxicity in human cervix, colon, and oral carcinoma...		Apoptosis , Anti-infection , Antibacterial , Antifungal
T5S0506	Rotundic acid	Rutundic acid	Apoptosis , Others , p38 MAPK , Akt , mTOR
	Rotundic acid (Rutundic acid), a natural compound, exhibit cytotoxic activities toward human hepatocellular carcinoma (HepG2), malignant melanoma (A375), SCLC (NCI-H446), breast cancer (MCF-7), and colon cancer (HT-29) c...		Apoptosis , Others , p38 MAPK , Akt , mTOR
T5646	Cinnamic acid	3-Phenylacrylic acid,β-Phenylacrylic acid	Endogenous Metabolite
	Cinnamic acid (β-Phenylacrylic acid) has potential use in cancer intervention,The concentration causing a 50% reduction of cell proliferation (IC50) ranged from 1 to 4.5 mM in glioblastoma, melanoma, prostate and lung ca...		Endogenous Metabolite
T1284	Megestrol acetate	SC10363,BDH1298	Glucocorticoid Receptor , Estrogen/progestogen Receptor , Progesterone Receptor , HIV Protease , Autophagy
	Megestrol acetate (BDH1298) is a progestogen with actions and uses similar to those of the progestogens in general. Megestrol acetate also has anti-androgenic properties. It is given by mouth in the palliative treatment ...
T4S0553	Theaflavin-3'-Gallate	Theaflavin 2B,THEAFLAVIN 3'-O-GALLATE	Others
	Theaflavin-3'-Gallate (Theaflavin 2B) usually comes from the leaves of Camellia sinensis (L.) O. Kuntze. Theaflavin-3'-gallate, act as prooxidants and induce oxidative stress, with carcinoma cells more sensitive than nor...		Others
T7044	Norepinephrine	Levophed,Levonoradrenaline,Aktamin,Nor-Epirenan,Levonor,Arterenol	MMP , Endogenous Metabolite , Adrenergic Receptor , Autophagy
	Norepinephrine (Levophed) can stimulate apoptosis in adult rat ventricular myocytes by activation of the β-adrenergic pathway. It can up-regulate the expression of vascular endothelial growth factor, matrix metalloprotei...
TN1721	Gypenoside L		ERK , p38 MAPK , Calcium Channel , NF-κB , ROS
	Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release. It also inhibit non-small cell lung carcinoma A549 cell inhibitory a...		ERK , p38 MAPK , Calcium Channel , NF-κB , ROS
T3902	Atractylenolide III	ICodonolactone,8β-Hydroxyasterolide	Apoptosis
	Atractylenolide III (ICodonolactone) may have therapeutic potential in treating homocysteine-mediated cognitive impairment and neuronal injury. Atractylenolide III is a potential candidate for the treatment of human lung...		Apoptosis
TN1854	Lasiodin	Lasiokaurin	P450 , PARP , Caspase
	Lasiodin (Lasiokaurin) is a diterpene compound from the plant Camellia sinensis that inhibits the proliferation of NPC cells. Lasiodin has antioxidant, antitumor and antibacterial activities, induces cell cycle length an...		P450 , PARP , Caspase
T6S0117	Avicularin	Fenicularin	ERK
	Avicularin (Fenicularin) has anti-allergic, anti-inflammatory, hepatoprotective, antioxidant, anti-tumor and other activities. It ameliorates human hepatocellular carcinoma by modulating the activities of NF-κB(p65), COX...		ERK
TN3048	4-Methoxycinnamaldehyde	p-Methoxycinnamaldehyde	RSV
	4-Methoxycinnamaldehyde (p-Methoxycinnamaldehyde) is an active ingredient of Agastache rugosa.4-Methoxycinnamaldehyde has cytoprotective activity against respiratory syncytial virus (RSV) in human laryngeal carcinoma cel...		RSV
T2S0837	Astragalus Polysacharin	2-(Chloromethyl)-4-(4-nitrophenyl)thiazole,89250-26-0	TAM Receptor
	2-(Chloromethyl)-4-(4-nitrophenyl)thiazole is a natural product derived from Astragalus propinquus.2-(Chloromethyl)-4-(4-nitrophenyl)thiazole exhibits anticancer activity. 2-(Chloromethyl)-4-(4-nitrophenyl)thiazole posse...		TAM Receptor
T3S0081	Oxypeucedanin	(+-)-Oxypeucedanin,Oxypeucadanin	Potassium Channel
	1. Oxypeucedanin ((+-)-Oxypeucedanin) has novel anticancer effect, mediated via induction of G2-M cell cycle arrest and apoptosis in human prostate carcinoma DU145 cells. 2. Oxypeucedanin is a kind of open-channel blocke...		Potassium Channel
TN6694	5,6-Benzoflavone	β-Naphthoflavone,beta-NF	Antioxidant
	5,6-Benzoflavone (β-Naphthoflavone) is an exogenous ligand for the aryl hydrocarbon receptor, which disrupts zinc homeostasis in human hepatocellular carcinoma HepG2 cells. 5,6-Benzoflavone (β-Naphthoflavone) possesses a...		Antioxidant
TN1880	Lucidenic acid B	Lucidenicacid B	Apoptosis , Caspase
	Lucidenic acid B (Lucidenicacid B), a natural compound extracted from Ganoderma lucidum, induces activation of caspase-9 and caspase-3 and cleavage of PARP, which can induce apoptosis in human leukemia cells through mito...		Apoptosis , Caspase
T3S0737	Flavokawain A	Flavokavain A	Apoptosis , p38 MAPK
	NSC-37445 has anti-tumor activity, such as inhibits growth of bladder tumor cells in a nude mice model , prevents the recurrence and progression of non-muscle-invasive urothelial cell carcinoma. NSC-37445 can significant...		Apoptosis , p38 MAPK
T6S1699	Shogaol	[6]-Shogaol,6-Shogaol	Lipoxygenase , Autophagy
	1. 6-Shogaol (6-Shogaol) has antipyretic and analgesic effects in addition to inhibitory effect on lipoxygenase activity. 2. 6-shogaol has anti-inflammatory property, reduces the inflammatory response and protected the f...		Lipoxygenase , Autophagy
T4S0145	Corylifol A	Corylinin	hCE , STAT , UGT
	1. Corylifol A (Corylinin) displays cytotoxic activity against HepG2 and Hep3B hepatocellular carcinoma cell lines, with IC50 values of 4.6 and 13.5 ug/ml, respectively. 2. Corylifol A and Biochanin A can be the potentia...		hCE , STAT , UGT
TN2029	P-Hydroxy-5,6-dehydrokawain	4'-Hydroxydehydrokawain	Others
	p-Hydroxy-5,6-dehydrokawain (4'-Hydroxydehydrokawain) is isolated from Kawain.		Others
TN5171	Tricetin		Apoptosis , Others , Nrf2
	Tricetin is a flavonoid isolated from pomegranate.Tricetin is a potent competitive inhibitor of Keap1-Nrf2 protein-protein interaction (PPI) and protects Parkinson's disease patients from 6-OHDA-induced neurotoxicity by ...		Apoptosis , Others , Nrf2
T5S2343	Acetylshikonin	Acetyl shikonin	Others , P450 , AChE
	1. Acetylshikonin exhibits weak cytotoxicity against human umbilical vein endothelial cells (HUVECs) with IC5 of over 2 microM, exhibits the antiangiogenic and antitumorigenic effects by suppressing proliferation and ang...		Others , P450 , AChE
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Natural Products

Sclareol

T3020

Synonym:

Target: Apoptosis, Others

Target: NF-κB, Integrin

Oxysophocarpine

T2786

Synonym:

Target: Prostaglandin Receptor

Synonym: N-Feruloyloctopamine

Target: p38 MAPK, Akt

Ganoderic acid D

T5S1133

Synonym:

Target: Apoptosis, Sirtuin

Target: Apoptosis, Antibacterial, Parasite

β-Aminopropionitrile

T13475

Synonym: 3-Aminopropionitrile,BAPN

Target: Others, Endogenous Metabolite

Embelin

T6485

Synonym: NSC 91874,Emberine,Embelic acid

Target: Apoptosis, NF-κB, Lipoxygenase, IAP, Prostaglandin Receptor, Autophagy

Oglufanide

T7203

Synonym: L-Glutamyl-L-tryptophan,H-Glu-Trp-OH

Target: VEGFR, HCV Protease, Endogenous Metabolite

Puerarin-4'-O-β-D-glucopyranoside

T12581

Synonym: Puerarin4'-O-glucoside

Target: Others

Daunorubicin hydrochloride

T1511

Synonym: Daunomycin HCl,RP-13057 Hydrochloride,Rubidomycin hydrochloride,Daunorubicin HCl,Daunomycin

Target: Apoptosis, DNA/RNA Synthesis, Topoisomerase, Antibacterial, Antibiotic, Autophagy

Berberine

T4S0797

Synonym: Berberin,Umbellatine

Target: Reactive Oxygen Species, Topoisomerase, Endogenous Metabolite, Antibacterial, Antibiotic, Autophagy

Hypophyllanthin

TN1757

Synonym:

Target: Potassium Channel, Calcium Channel, P-gp

Cucurbitacin D

TN1013

Synonym:

Target: IL Receptor, JNK, STAT

Synonym: Silibinin A,Silybin,Silymarin I

Target: Reactive Oxygen Species, Autophagy

4,6-Benzilidine-D-Glucose

Target: Akt, Caspase, PI3K, STAT, mTOR

Theaflavin-3-gallate

T3051

Synonym: Theaflavine-3-Gallate

Target: Estrogen/progestogen Receptor, Progesterone Receptor

Synonym: Guanine deoxyriboside,Deoxyinosine

Target: Others, Endogenous Metabolite

Synonym: Quercetagetin 3,6,7,4'-Tetramethyl Ether,Vitexicarpin

Target: STAT

Ponicidin

T2S1975

Synonym: Rubescensine B

Target: Apoptosis, JAK, STAT

Dictamine

T5746

Synonym: Dictamnine,Dectamine

Target: Apoptosis, Anti-infection, Antibacterial, Antifungal

Rotundic acid

T5S0506

Synonym: Rutundic acid

Target: Apoptosis, Others, p38 MAPK, Akt, mTOR

Cinnamic acid

T5646

Synonym: 3-Phenylacrylic acid,β-Phenylacrylic acid

Target: Endogenous Metabolite

Megestrol acetate

T1284

Synonym: SC10363,BDH1298

Target: Glucocorticoid Receptor, Estrogen/progestogen Receptor, Progesterone Receptor, HIV Protease, Autophagy

Theaflavin-3'-Gallate

T4S0553

Synonym: Theaflavin 2B,THEAFLAVIN 3'-O-GALLATE

Target: Others

Norepinephrine

T7044

Synonym: Levophed,Levonoradrenaline,Aktamin,Nor-Epirenan,Levonor,Arterenol

Target: MMP, Endogenous Metabolite, Adrenergic Receptor, Autophagy

Gypenoside L

TN1721

Synonym:

Target: ERK, p38 MAPK, Calcium Channel, NF-κB, ROS

Atractylenolide III

T3902

Synonym: ICodonolactone,8β-Hydroxyasterolide

Target: P450, PARP, Caspase

4-Methoxycinnamaldehyde

TN3048

Synonym: p-Methoxycinnamaldehyde

Target: RSV

Astragalus Polysacharin

T2S0837

Synonym: 2-(Chloromethyl)-4-(4-nitrophenyl)thiazole,89250-26-0

Target: TAM Receptor

Oxypeucedanin

T3S0081

Synonym: (+-)-Oxypeucedanin,Oxypeucadanin

Target: Potassium Channel

5,6-Benzoflavone

TN6694

Synonym: β-Naphthoflavone,beta-NF

Target: Antioxidant

Lucidenic acid B

TN1880

Synonym: Lucidenicacid B

Target: Apoptosis, Caspase

Flavokawain A

T3S0737

Synonym: Flavokavain A

Target: Apoptosis, p38 MAPK

Shogaol

T6S1699

Synonym: [6]-Shogaol,6-Shogaol

Target: Lipoxygenase, Autophagy

Corylifol A

T4S0145

Synonym: Corylinin

Target: hCE, STAT, UGT

p-Hydroxy-5,6-dehydrokawain

TN2029

Synonym: 4'-Hydroxydehydrokawain

Target: Apoptosis, Others, Nrf2

Acetylshikonin

T5S2343

Synonym: Acetyl shikonin

Target: Others, P450, AChE

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Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPJ-00705	BCAS2 Protein, Human, Recombinant (His, T7)	Human	E. coli
	Breast Carcinoma-Amplified Sequence 2 (BCAS2) is a member of the SPF27 family. BCAS2 is a nuclear protein and widely expressed in many rtissues. BCAS2 is identified as being overexpressed in various breast cancer cell li...
TMPJ-00381	PIGR Protein, Human, Recombinant (hFc)	Human	Human Cells
	PIGR binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates ...
TMPJ-01093	HYAL1 Protein, Human, Recombinant (His)	Human	Human Cells
	Hyaluronidase-1 (HYAL1) is a secreted lysosomal hyaluronidase that belongs to the glycosyl hydrolase 56 family. HYAL1 contains one EGF-like domain and is highly expressed in the liver, kidney, and heart, but it is weakly...
TMPJ-01362	UBAP1 Protein, Human, Recombinant (His)	Human	E. coli
	Ubiquitin-Associated Protein 1 (UBAP1) belongs to the UBA domain family. Members of this family are related to ubiquitin and the ubiquitination pathway. Because of their cytogenetic location, this UBA domain family membe...
TMPJ-00654	LGALS8 Protein, Human, Recombinant	Human	E. coli
	The Galectin family of proteins, with specificity for Nacetyllactosaminecontaining glycoproteins, consists of beta-galactoside binding lectins containing homologous carbohydrate recognition domains (CRDs). They also poss...
TMPJ-00797	LDHB Protein, Human, Recombinant (His)	Human	E. coli
	L-Lactate Dehydrogenase B Chain (LDH-B) is a member of the lactate dehydrogenase family that consists of three members, LDH-A, LDH-B and LDH-C; members of this family function as powerful markers for germ cell tumors. LD...
TMPJ-00155	Mucin-1/MUC1 Protein, Human, Recombinant (hFc&Avi), Biotinylated	Human	Human Cells
	Mucin-1, is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also ...
TMPH-01277	ENOX2 Protein, Human, Recombinant	Human	E. coli
	May be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a ...
TMPH-01278	ENOX2 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	May be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a ...
TMPJ-00724	LDHA Protein, Human, Recombinant (His)	Human	E. coli
	L-Lactate Dehydrogenase A Chain (LDHA) is an enzyme that catalyzes the conversion of L-lactate and NAD+ to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA contains an N-terminal coenzyme binding region,...
TMPJ-00928	Serpin B3 Protein, Human, Recombinant (C-His)	Human	Human Cells
	Serpin B3, also known as squamous cell carcinoma antigen-1 (SCCA-1), is a member of the serpin superfamily of serine protease inhibitors. Serpin B3 belongs to the subgroup ovalbumin-related serpins which are involved in ...
TMPJ-00929	Serpin B3 Protein, Human, Recombinant (N-His)	Human	E. coli
	Serpin B3, also known as squamous cell carcinoma antigen-1 (SCCA-1), is a member of the serpin superfamily of serine protease inhibitors. Serpin B3 belongs to the subgroup ovalbumin-related serpins which are involved in ...
TMPJ-01108	SMAD4 Protein, Human, Recombinant (His)	Human	E. coli
	SMAD Family Member 4 (SMAD4) is a cytoplasmic protein that belongs to the Dwarfin/SMAD family. SMAD4 contains one MH1 (MAD homology 1) domain and one MH2 (MAD homology 2) domain. It is the component of the heterotrimeric...
TMPJ-00345	IGF2BP-2 Protein, Human, Recombinant (His)	Human	E. coli
	Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 (IGFBP2) belongs to the RRM IMP/VICKZ family. IGFBP2 is a cytoplasmic protein and contains four KH domains and two RRM (RNA recognition motif) domains. IGF2BP2 binds to...
TMPJ-00755	CRYAB Protein, Human, Recombinant (His)	Human	E. coli
	α Crystallin B Chain (CRYAB) is a cytoplasmic protein that belongs to the small heat shock protein (HSP20) family. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectiv...
TMPJ-01010	PLA2G16 Protein, Human, Recombinant (His)	Human	E. coli
	Group XVI Phospholipase A1/A2 (PLA2G16) belongs to the H-rev 107 family. PLA2G16 is expressed in a number of human tumors including ovarian carcinomas, lung carcinomas. PLA2G16 is involved in the regulation of differenti...
TMPH-01297	DDR1 Protein, Human, Recombinant (aa 21-417, His)	Human	HEK293
	Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival ...
TMPY-00403	FGF-7/KGF Protein, Human, Recombinant (His)	Human	E. coli
	Fibroblast growth factor 7 (FGF7) is a member of the fibroblast growth factor (FGF) family of proteins. FGF7 plays an important role in regulating the proliferation, migration, and differentiation of cells. FGF7 is of st...
TMPY-00545	Dermcidin Protein, Human, Recombinant (hFc)	Human	HEK293
	Hepatocellular carcinoma (HCC) is a major contributor to cancer-related deaths due to its often late stage diagnosis, and dermcidin (DCD) may have the potential to be used as a serum biomarker for HCC for more timely dia...
TMPY-01283	Glypican 3/GPC3 Protein, Human, Recombinant (His)	Human	HEK293
	Glypican-3, also known as Intestinal protein OCI-5, GPC3, and OCI5, is a member of the glypican family. It belongs to the glypican family and is highly expressed in the lung, liver, and kidney. It is a heparan sulfate pr...
TMPY-00502	Glypican 3/GPC3 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus-Insect Cells
	Glypican-3, also known as Intestinal protein OCI-5, GPC3, and OCI5, is a member of the glypican family. It belongs to the glypican family and is highly expressed in the lung, liver, and kidney. It is a heparan sulfate pr...
TMPY-03878	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)	Human	HEK293
	Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in th...
TMPY-04643	Integrin alpha V beta 6 Protein, Mouse, Recombinant (Flag & His)	Mouse	HEK293
	Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in th...
TMPJ-01465	GM-CSF/CSF2 Protein, Human, Recombinant (E. coli)	Human	E.coli
	Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of...
TMPY-01008	VEGFD Protein, Human, Recombinant (His)	Human	HEK293
	Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active...
TMPY-00408	PCSK9 Protein, Human, Recombinant (D374Y & V474I & G670E, His)	Human	HEK293
	Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the sec...
TMPY-05131	PCSK9 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the sec...
TMPY-01897	PRSS3 Protein, Human, Recombinant (His)	Human	HEK293
	Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains on...
TMPY-04966	PCSK9 Protein, Human, Recombinant (D374Y, His)	Human	HEK293
	Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the sec...
TMPY-02568	IL-1 beta/IL-1F2 Protein, Canine, Recombinant	Canine	E. coli
	Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair ...
TMPY-02134	IL-1 beta/IL-1F2 Protein, Mouse, Recombinant	Mouse	E. coli
	Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair ...
TMPY-00690	Carbonic Anhydrase 9 Protein, Human, Recombinant (His)	Human	HEK293
	Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzym...
TMPY-01999	IL-1 beta/IL-1F2 Protein, Human, Recombinant (His)	Human	E. coli
	Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair ...
TMPY-00689	Carbonic Anhydrase 9 Protein, Human, Recombinant (hFc)	Human	HEK293
	Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzym...
TMPY-02445	IL-1 beta/IL-1F2 Protein, Rhesus, Recombinant	Rhesus	E. coli
	Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair ...
TMPY-02227	IL-1 beta/IL-1F2 Protein, Rat, Recombinant (mature form)	Rat	E. coli
	Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair ...
TMPY-01049	IL-1 beta/IL-1F2 Protein, Human, Recombinant	Human	E. coli
	Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair ...
TMPY-05081	Notch 1 Protein, Human, Recombinant (hFc)	Human	HEK293
	NOTCH1 is one of the four mammalian Notch receptors, which is involved in the Notch signaling pathway. Specifically, NOTCH1 promotes the proliferation of myogenic precursor cells, and the NICD domain of NOTCH1 can impair...
TMPY-02509	Alpha-fetoprotein Protein, Human, Recombinant (His)	Human	HEK293
	Alpha-fetoprotein (AFP) is classified as a member of the albuminoid gene superfamily consisting of albumin, AFP, vitamin D (Gc) protein, and alpha-albumin. AFP is a glycoprotein of 591 amino acids and a carbohydrate moie...
TMPY-01431	L1CAM Protein, Human, Recombinant (His)	Human	HEK293
	L1 cell adhesion molecule (L1CAM), also designated as CD171, is a cell adhesion receptor of the immunoglobulin superfamily, known for its roles in nerve cell function. While originally believed to be present only in brai...
TMPY-02785	Tetranectin Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Tetranectin (TN), also known as C-type lectin domain family 3, member B (CLEC3B) is a member of the C-type lectin Family. It is plasminogen kringle 4 binding protein and regulates fibrinolysis and proteolytic processes v...
TMPY-02450	Cathepsin D Protein, Human, Recombinant (His)	Human	HEK293
	Cathepsin D (CTSD), a well known lysosomal aspartyl protease and belongs to the peptidase C1 family, which is a normal and major component of lysosomes, and is found in almost all cells and tissues of mammals. Its mostly...
TMPY-01289	DDR1 Protein, Human, Recombinant (His)	Human	HEK293
	Discoidin domain receptor family, member 1 (DDR1), also known as or CD167a (cluster of differentiation 167a), and Mammary carcinoma kinase 10 (MCK10), belongs to a subfamily of tyrosine kinase receptors with an extracell...
TMPY-00566	CCL18 Protein, Human, Recombinant (His)	Human	Yeast
	CCL18 is a chemotactic cytokine involved in the pathogenesis and progression of various disorders, including cancer. Proof showed high levels of CCL18 in the serum of epithelial ovarian carcinoma patients suggesting its...
TMPY-01068	CD70 Protein, Human, Recombinant (hFc)	Human	HEK293
	CD70, a member of the tumor necrosis factor superfamily, is restricted to activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its receptor, CD27, is important in priming, effector functions, diff...
TMPY-01477	MMP-2 Protein, Human, Recombinant	Human	HEK293
	Matrix Metalloproteinase-2 (MMP-2) is an enzyme that degrades components of the extracellular matrix and thus plays a pivotal role in cell migration during physiological and pathological processes. MMP-2 expression is de...
TMPY-01139	PDGFRA Protein, Human, Recombinant (His)	Human	HEK293
	PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived growth factor family. They are members of the class III subfami...
TMPY-00991	LIFR Protein, Human, Recombinant (His)	Human	HEK293
	LIFR (leukemia inhibitory factor receptor) belongs to the family of cytokine receptors. LIFR forms a high-affinity receptor complex with gp130, which mediates the activity of LIF (leukemia inhibitory factor) and thus aff...
TMPY-05493	LIFR Protein, Human, Recombinant (hFc)	Human	HEK293
	LIFR (leukemia inhibitory factor receptor) belongs to the family of cytokine receptors. LIFR forms a high-affinity receptor complex with gp130, which mediates the activity of LIF (leukemia inhibitory factor) and thus aff...
TMPY-05157	TGFBR2 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	TGFBR2 is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. It is a transmembrane protein. TGFBR2 is comprised of a C-terminal protein kinase domain and an N-terminal ectodomain. The ectodoma...
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