240 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T29067	Upacicalcet	PLS-240,SK-1403,AJT-240	Calcium Channel
	Upacicalcet (AJT-240) is an intraventricular calcium mimetic, a SHPT available for human hemodialysis, that inhibits excessive parathyroid hormone (PTH) secretion by directly acting on parathyroid cell membrane calcium-s...		Calcium Channel
T29236	ZTZ240	ZTZ 240,ZTZ-240
	ZTZ240, a KCNQ2 K+ channel activator, offers a new target to treat hyperexcitability disorders.
T3535	ML240		p97
	ML240 is a selective, ATP-competitive p97 inhibitor.		p97
T67842	ERG240	EGR240	Others
	ERG240 is an inhibitor of branched-chain amino acid aminotransferase 1 (BCAT1). ERG240 can be used for the research of rheumatoid arthritis, cancer, and bone disease.		Others
T30666	C.I. Food Blue 1-aluminum lake	EINECS 240-589-3,Indigotine-aluminum lake,Acid Blue 74-aluminum lake,Pigment Blue 63
	C.I. Food Blue 1-aluminum lake is a type of colorant.
T40495	Elastase from porcine pancreas	EC 3.2.1.35	Others
	Porcine pancreatic elastase is a serine protease composed of a single polypeptide chain with 240 amino acid residues. It has the ability to hydrolyze polypeptides and proteins, and can induce emphysema in hamsters.		Others
T16889	SJ572403	SJ403	Others
	SJ572403 is an inhibitor of disordered protein p27 with Kd of 2.2 mM for specific regions within the D2 subdomain of p27-KID. SJ572403 can be used in studies about diseases with intrinsically disordered proteins.		Others
T2248	AS-605240	AS 605240	PI3K , Autophagy
	AS-605240 is an effective and specific inhibitor of PI3Kγ (IC50/Ki: 87.8 nM).		PI3K , Autophagy
T14501	BAY-2402234		Dehydrogenase , DNA/RNA Synthesis
	BAY-2402234 is an inhibitor of dihydroorotate dehydrogenase (DHODH) for the treatment of myeloid malignancies.BAY 2402234 is a selective low-nanomolar inhibitor of human DHODH enzymatic activity.		Dehydrogenase , DNA/RNA Synthesis
T61122	ZINC12409120	R-4584	ERK
	ZINC12409120 (R-4584) is a selective ERK inhibitor.ZINC12409120 inhibits ERK with an IC50 of 5.0 μM.ZINC12409120 inhibits ERK activity by interfering with FGF23:α-Klotho interaction.		ERK
TP1127L1	Nemifitide acetate(173240-15-8 free base)	INN 00835 acetate	5-HT Receptor
	Nemifitide acetate(173240-15-8 free base) (INN 00835 acetate) is a synthetic pentapeptide antidepressant with a potential for rapid onset of action. It is a peptide analog of melanocyte-inhibiting factor (MIF).		5-HT Receptor
TQ0139	VU 0240551	N-(4-Methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide,VU0240551-2-D4	Potassium Channel , Calcium Channel , HER
	VU 0240551 is a selective antagonist of neuronal K-Cl cotransporter KCC2 inhibitor with an IC50 of 560 nM. VU 0240551 inhibits L-type calcium channels and hERG.		Potassium Channel , Calcium Channel , HER
T32490	L-161240	L-161,240	Antibacterial
	L-161240 is an antimicrobial agent associated with lipid A biosynthesis with an IC50 value of 30 nM as determined by DEACET and a MIC value of 1-3 μg/ mL against wild-type E. coli.		Antibacterial
T13248	UK-240455		NMDAR , iGluR
	UK-240455 is a potent and selective N-methyl-D-aspartic acid (NMDA) glycine receptor antagonist with neuroprotective effects and improved motor function in Parkinson's disease models, and is a potential candidate compoun...		NMDAR , iGluR
T61702	SRI-37240
	SRI-37240 is a powerful inhibitor of premature termination codons (PTCs). It effectively suppresses CFTR nonsense mutations and induces changes in cellular translation termination at PTCs in HEK293T cells. Additionally, ...
T5048	SSR240612		Bradykinin Receptor
	SSR240612 is a potent, and orally active specific non-peptide bradykinin B1 receptor antagonist (Kis = 0.48-0.73 and 358-481 nM for B1 and B2 receptors, respectively).		Bradykinin Receptor
T2081	LY2409881 trihydrochloride	LY2409881	Apoptosis , IκB/IKK
	LY2409881 trihydrochloride is a novel specific inhibitor of IKK2 (IC50: 30 nM); IC50 for IKK1 and other common kinases is at least one log higher.		Apoptosis , IκB/IKK
T4760	KSD 2405	3-Hydroxybenzyl alcohol	Others , Endogenous Metabolite
	KSD 2405 (3-Hydroxybenzyl alcohol) is a hydroxybenzyl alcohol that is phenol substituted at position C-3 by a hydroxymethyl group. It is a pink or beige to brown crystalline powder, soluble in water.		Others , Endogenous Metabolite
T15802	LY2183240		FAAH , Autophagy
	LY2183240 inhibits fatty acid amide hydrolase (FAAH) activity (IC50 = 12.4 nM). LY2183240 is a novel and highly effective blocker of anandamide uptake (IC50 = 270 pM).		FAAH , Autophagy
T30662	C.I. 74240	NSC 324570,NSC-324570,NSC324570
	C.I. 74240 is a copper-containing dye used as a gelling agent for lubricants, for staining of bacteria and for the dyeing of histiocytes and fibroblasts in vivo.