ache — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T40335	AChE-IN-3		NO Synthase , AChE
	AChE-IN-3 had inhibitory effect on AChE and stronger inhibitory effect on NO, with EC50 of 0.57 μM.		NO Synthase , AChE
Fr12799	AChE-IN-23
	AChE-IN-23 (compound 3h) is an inhibitor of acetylcholinesterase (AChE) with an IC 50 value of 48.3 μM [1].
T77758	AChE/BuChE-IN-4		AChE
	AChE/BuChE-IN-4 is a multi-target AChE/BuChE inhibitor with oral activity and blood-brain barrier permeability, with IC50 values of 2.08 and 7.41 μM for AChE and BuChE, respectively.		AChE
T9989	AChE-IN-27		Others
	AChE-IN-27 is a small molecule used for high-throughput assays.		Others
T62360	AChE-IN-26		AChE
	AChE-IN-26 (compound 4a) is an AChE (acetylcholinesterase) inhibitor (IC50: 0.42 μM).		AChE
T77352	ACHE Inhibitor 12
	ACHE Inhibitor 12 inhibited acetylcholinesterase with an IC50 value of 0.38 µM.
T61969	AChE/BChE-IN-10		AChR , AChE
	AChE/BChE-IN-10 is a potent dual inhibitor of AChE and BChE with IC50 values of 0.176, and 0.47 μM, respectively. AChE/BChE-IN-10 exhibits good blood brain barrier permeability. AChE/BChE-IN-10 can inhibit Aβ-aggregation...		AChR , AChE
T80671	ACHE-IN-38	5,6-Dimethoxy-2-(piperidin-4-yl)methylene-indan-1-one	Antifungal
	ACHE-IN-38 is a potent Acetylcholinesterase inhibitor that can be used for the synthesis of compounds with anti-inflammatory, anti-tumor, and antibacterial activities.		Antifungal
T60891	AChE/BChE/MAO-B-IN-1		MAO , AChE
	AChE/BChE/MAO-B-IN-1 is a reversible, non-time-dependent inhibitor of AChE, BChE and MAO-B that crosses the blood-brain barrier and exhibits inhibitory effects on hAChE, hBChE and hMAO-B with IC50s of 7.31, 0.56 and 26.1...		MAO , AChE
T62728	AChE-IN-24
	AChE-IN-24 is a potent inhibitor of AChE that crosses the blood-brain barrier. hAChE is strongly inhibited by AChE-IN-24 (IC50: 0.053 μM). aChE-IN-24 can be used to study Alzheimer's disease (AD).
T61049	AChE-IN-11
	AChE-IN-11 (compound 5C) can be used in the Alzheimer's disease research with neuroprotective effects and good antioxidant activity (ORAC = 2.5 eq). AChE-IN-11 is a good multifunctional agent with IC 50 values of 7.9 μM...
T63628	AChE-IN-19
	AChE-IN-19 is a potent inhibitor of AChE (IC50: 0.56 μM) and also exhibits inhibition of Aβ aggregation. aChE-IN-19 exhibits neuroprotective effects and is virtually non-toxic to SH-SY5Y cells. aChE-IN-19 can be used to ...
T61845	AChE-IN-21
	AChE-IN-21 (Compound I-8) is a highly potent and selective orally active inhibitor of acetylcholinesterase (AChE). It exhibits an impressive inhibitory concentration (IC50) of 2.66 nM. Additionally, AChE-IN-21 demonstrat...
T83186	AChE-IN-42
	Compound AChE-IN-42, also known as Compound 28, is an acetylcholinesterase (AChE) inhibitor with an inhibition constant (K i) of 0.44 μM [1].
T83185	AChE-IN-43
	AChE-IN-43 is a potent, selective AChE inhibitor with a K i of 0.41 μM, applicable in the study of neurological diseases [1].
T74382	AChE-IN-4
	AChE-IN-4 is an acetylcholine esterase inhibitor (AChEI) with an IC50 value of 24.1 μM.
T63307	AChE-IN-6
	AChE-IN-6 is an optimal multifunctional ligand that significantly inhibits AChE activity with IC50 values of 0.20 μM and 37.02 nM for EeAChE and HuAChE, respectively, and has anti-Aβ activity (IC50= 1.92 μM for self-indu...
T79583	AChE-IN-36
	AChE-IN-36 (compound A4) is an acetylcholinesterase inhibitor with an IC50 of 0.04 μM, influencing ROS levels and modulating the gene expression of NRF2 [1].
T62538	AChE-IN-15
	AChE-IN-15 (Compound 3d) is a reversible inhibitor of human acetylcholinesterase (huAChE) and human butyrylcholinesterase (huBChE) with IC50 values of 6.8 μM and 16.1 μM for huAChE and huBChE, respectively, with signific...
T79584	AChE-IN-37
	AChE-IN-37 (compound A2) is an acetylcholinesterase inhibitor with an inhibitory concentration (IC50) of 0.23 µM. It alters reactive oxygen species (ROS) levels and modulates the gene expression of nuclear factor erythro...