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Search Results for " advanced "

Targets

131

Compounds

20

Natural Products

70

Recombinant Proteins

7

Libraries

Cat No. Product Name Synonyms Targets
T12695 RBN-2397 PARP
RBN-2397 is a potent, selective and orally active accross species NAD+ competitive PARP7 inhibitor with IC50 less than 3 nM.
T9756 AZD-9574 PARP
AZD-9574 is a selective inhibitor of PARP1 at the sites of SSBs. AZD-9574 exhibits anti-cancer activities and can be used in studies about HRD+ breast cancer and advanced solid malignancies.
T38050 CP-609754 Transferase
CP-609754 (LNK-754) is a potent and reversible farnesyltransferase inhibitor with potential anticancer activity.The IC50 for inhibiting farnesylation of recombinant human H-Ras is 0.57 ng/mL and recombinant K-Ras is 46 n...
T3124 Carbendazim Bavistin,Carbendazole,Mercarzole Antifungal
Carbendazim (Mercarzole) is a broad-spectrum benzimidazole antifungal with potential antimitotic and antineoplastic activities. Although the exact mechanism of action is unclear, carbendazim appears to binds to an unspec...
T8327 ONO-7475 Trk receptor , TAM Receptor
ONO-7475 is an inhibitor with high specificity for anexelekto and MER tyrosine kinase
T26889 Borofalan(10B) L-4-Boronophenylalanine Others
Borofalan(10B) (L-4-Boronophenylalanine) echibits antineoplastic effects. Borofalan can be used in studies on recurrent or locally advanced head and neck cancer.
T7369L Gemigliptin Tartrate(911637-19-9 free base) LC15-0444 tartrate Proteasome , DPP-4
Gemigliptin Tartrate (LC15-0444 tartrate) is a highly selective, reversible and competitive inhibitor of dipeptidyl peptidase-4 (DPP-4). It has an IC50 of 10.3 nM for human recombinant DPP-4. Gemigliptin tartrate exhibit...
T30190 Ataquimast Others
Ataquimast is used in curing advanced receptor-positive breast cancer.
T26978 CEP-40125 RXDX-107 DNA Alkylation
CEP-40125 (RXDX-107) is a DNA alkylating agent for the study of advanced solid tumors.
T2669 Berzosertib VX-970,VE-822 ATM/ATR
Berzosertib (VE-822) has been used in trials studying the treatment of Ovarian Neoplasms, Ovarian Serous Tumor, Adult Solid Neoplasm, Advanced Solid Tumor, and Advanced Solid Neoplasm, among others.
T24818 Sparfosic Acid NSC224131,NSC-224131,Acide sparfosique,N-Phosphonacetyl-L-aspartate,NSC 224131 Apoptosis
Sparfosic Acid (Acide sparfosique) is an aspartate carbamoyltransferase inhibitor with antitumor activity and can be used to study advanced renal cell carcinoma.
T1103 Aminoglutethimide DL-Aminoglutethimide,BA-16038,NSC-330915 Aromatase
Aminoglutethimide (BA-16038), an aromatase inhibitor, is used in the therapy of advanced BREAST Y.
T17216 Valspodar PSC 833 P-gp
Valspodar (PSC 833) is a specific P-glycoprotein inhibitor and MDR regulator often used as a chemical sensitizer to study advanced epithelial ovarian cancer.
T15390 Glufosfamide D 19575,Glucosylifosfamide mustard Others
Glufosfamide is a novel oxazolophosphamide compound with anticancer activity for the study of advanced non-small cell lung cancer.
T11877 LR-90 Others
LR-90, an advanced glycation end product (AGE) inhibitor, is utilized in diabetic animal model research. This compound effectively suppresses inflammatory responses in human monocytes.
T2361 LY2874455 LY 2874455,LY-2874455 VEGFR , FGFR
LY2874455 has been used in trials studying the treatment of Advanced Cancer.
T79157 Pimicotinib ABSK021,ABSK-021 c-Fms , Others
Pimicotinib (ABSK021) is a potent CSF1R inhibitor with antitumor activity and can be used to study advanced solid tumors.
T16026 MCI826 P-gp , LTR
MCI826 is a potent and selective antagonist of P-glycoprotein (P-gp) and peptide leukotrienes (p-LTs), showing anti-asthmatic activity in a guinea pig model of advanced asthma.
T36395 Trotabresib CC-90010 Epigenetic Reader Domain
Trotabresib (CC-90010) is an orally active inhibitor of BET and can be used in studies about advanced solid tumors.
T77149 Cobolimab TSR-022,GSK4069889 Others
Cobolimab (TSR-022) is a potent monoclonal antibody to TIM-3. Cobolimab induces internalization of TIM-3 with an IC50 value of 0.4464 nM. Cobolimab has antitumor activity and can be used to study advanced/metastatic mela...
T68065 Enloplatin
Enloplatin is a carboplatin analog that has a partial role in advanced ovarian cancer.
T39403 Avotaciclib BEY1107,Avotaciclib CDK
Avotaciclib (BEY1107) is a potent and orally active cyclin dependent kinase 1 (CDK1) inhibitor.Avotaciclib can be used to study locally advanced or metastatic pancreatic cancer.
T2113 PHA-793887 PHA 793887,PHA793887 Apoptosis , CDK
PHA-793887 has been used in trials studying the treatment of Advanced/Metastatic Solid Tumors.
T2145 Temsirolimus NSC 683864,CCI-779 Apoptosis , mTOR , Autophagy
Temsirolimus (CCI-779) is a specific mTOR inhibitor ( IC50: 1.76 μM), used in the treatment of advanced renal cell cancer.
T7143 Alagebrium chloride ALT711 Others , Endogenous Metabolite
Alagebrium chloride (ALT711) is an advanced glycation end product (AGE) inhibitor, and has proven effective in reducing systolic blood pressure and providing therapeutic benefit for patients with diastolic
T27259 Emitefur BOFA2,BOF A2,BOF-A2 Others
Emitefur (BOF-A 2) is an orally active and potent 5-fluorouracil derivative with anticancer and antitumor activity.Emitefur is used in advanced gastric cancer, breast cancer and metabolism-related diseases.
T11237 Camizestrant Estrogen receptor antagonist 2 Estrogen Receptor/ERR
Camizestrant (Estrogen receptor antagonist 2) is an antagonist of the estrogen receptor and can be used in studies about ER+ HER2-advanced breast cancer[1].
T40292 Opnurasib NVP-JDQ443,JDQ-443,Opnurasib Ras
Opnurasib (JDQ-443) is an orally available and selective and potent covalent KRAS G12C inhibitor with antitumor activity for the study of advanced non-small cell lung cancer.
T77359 Tezepelumab Tezepelumab-ekko,MEDI 19929,AMG 157 Others
Tezepelumab (AMG 157) is a humanized monoclonal antibody (IgG2λ) targeting TSLP that prevents TSLP from interacting with its heterodimer receptor. Tezepelumab can be used to study advanced asthma disease.
T76706 Varlilumab CDX-1127 TNF
Varlilumab (CDX-1127) is a novel human IgG1 anti-CD27 monoclonal antibody. Varlilumab has antitumor activity and can be used to study advanced solid tumors.
T60976 Bezuclastinib CGT9486,PLX 9486 c-Kit
Bezuclastinib (CGT9486) is a novel, potent and highly selective tyrosine kinase and c-kit D816V inhibitor for the study of advanced mastocytosis.
T8583 Tenilsetam 3-(2-thienyl)- (9CI),Piperazinone Others
Tenilsetam (Piperazinone) is an endonuclease modulator; a nootropic agent and advanced glycation end product (AGE) inhibitor having potential for Alzheimer's disease (AD) treatment.
T7598 Calcium N5-methyltetrahydrofolate NSC173328 Others , Antifolate
Calcium N5-methyltetrahydrofolate (NSC-173328) is the calcium salt of levomefolic acid, which has been proposed for treatment of cardiovascular disease and advanced cancers such as breast and colorectal cancers
T40199 Tulmimetostat CPI-0209 Histone Methyltransferase
Tulmimetostat (CPI-0209) is an orally active EZH1/EZH2 inhibitor.Tulmimetostat has antitumor activity and is used in the study of ovarian cancer and advanced solid tumors.
T2073 GSK2636771 GSK 2636771,GSK-2636771 PI3K
GSK2636771, an effective, specific, orally bioavailable, PI3Kβ inhibitor, has been used in cancer, lymphoma, solid neoplasm, recurrent solid neoplasm, and advanced malignant neoplasm.
T76696 Onvatilimab JNJ-61610588 Others
Onvatilimab (JNJ-61610588) is a human IgG1 κ-anti-Vista (T-cell-activated V-domain Ig inhibitor) monoclonal antibody. Onvatilimab has antitumor activity and can be used to treat advanced head and neck cancers.
T76761 Olaratumab LY3012207,IMC-3G3 PDGFR
Olaratumab(IMC-3G3) is a human monoclonal IgG1 antibody against platelet-derived growth factor receptor alpha (PDGFRα), which has antitumor effects and can be used to study advanced soft tissue sarcomas.
T2381 Abemaciclib CDK4/6 dual inhibitor,LY2835219 CDK
Abemaciclib (LY2835219) is a dual inhibitor of CDK4/6 (IC50=2/10 nM) with selectivity and specificity. Abemaciclib has antitumor activity and is used to treat advanced or metastatic breast cancer.
T1755 LY2090314 GSK-3
LY2090314, an effective GSK-3α/β inhibitor (IC50: 1.5 nM/0.9 nM), may improve the efficacy of platinum-based chemotherapy regimens. LY2090314 has been used in trials studying the treatment of Leukemia, Advanced Cancer, a...
T77006 Felzartamab TJ-202,MOR-03087,MOR-202 CD38
Felzartamab(MOR-202) is a human-targeted monoclonal antibody to CD38 for the study of multiple myeloma and advanced antibody-mediated rejection of allogeneic kidney transplants.
T83970 IMMH 010 maleate YPD-30 maleate PD-1/PD-L1
IMMH 010 maleate (YPD-30 maleate) is an orally available programmed cell death ligand 1 inhibitor with potential antitumor activity for the study of neurological disorders and advanced malignant solid tumors.
T0078 Lapatinib GSK572016,GW572016 EGFR , Ferroptosis , Autophagy
Lapatinib (GW572016) is an inhibitor of ErbB2 and EGFR (IC50=9.2/10.8 nM) with oral activity. Lapatinib has antitumor activity and can be used to treat advanced or metastatic breast cancer with HER2 overexpression.
T77750 Rosmantuzumab OMP-131R10 Others
Rosmantuzumab (OMP-131R10) is a humanized monoclonal antibody against R-spondin 3 (RSPO3). Rosmantuzumab has potential antitumor activity and can be used to study advanced relapsed refractory solid tumors.
T8875 CD73-IN-3 EX-A4254,LY-3475070 CD73
CD73-IN-3 (LY-3475070) is a potent and selective CD73 inhibitor with an IC50 of 28 nM, and its use alone or in combination with pembrolizumab is currently being tested in patients with advanced cancer.
T2507 Azeliragon TTP488 Beta Amyloid , advanced glycation end products
Azeliragon (TTP488) is an antagonist at the Receptor for Advanced Glycation End products; is evaluated as a potential treatment for patients with mild-to-moderate Alzheimer_acute_s disease (AD).
T1962 ASP3026 ASP 3026 Apoptosis , ALK
ASP3026 has been used in trials studying the treatment of Solid Tumor, B-Cell Lymphoma, Advanced Malignancies, Positive for Anaplastic Lymphoma Kinase, and Positive for Proto-Oncogene Tyrosine-Protein Kinase ROS.
T17028 Tefinostat CHR-2845 HDAC
Tefinostat (CHR-2845) is a potent monocyte/macrophage-targeted histone deacetylase (HDAC) inhibitor. Tefinostat is cleaved to the active acid CHR-2847 by the intracellular esterase human carboxylesterase-1 (hCE-1).Tefino...
T77138 Ragifilimab INCAGN-01876,INCAGN-1876,CM-701 TNF
Ragifilimab (INCAGN-1876) is an agonist monoclonal antibody targeting glucocorticoid-induced TNFR-associated protein (GITR). Ragifilimab can be used in the study of advanced or metastatic solid tumors.
T77440 Codrituzumab RG-7686,RO5137382,GC33
Codrituzumab (GC3) is a humanized antibody against the glypican-3 hepatocellular carcinoma protein that can be used in combination with sorafenib to study incurable advanced hepatocellular carcinoma (HCC).
T2709 TAK-901 TAK901 JAK , CDK , Src , Aurora Kinase
TAK-901 has been used in trials studying the treatment of Lymphoma, Myelofibrosis, Multiple Myeloma, Myeloid Metaplasia, and Advanced Solid Tumors, among others.

Compounds

RBN-2397
T12695
Synonym:
Target: PARP
AZD-9574
T9756
Synonym:
Target: PARP
CP-609754
T38050
Synonym:
Target: Transferase
Carbendazim
T3124
Synonym: Bavistin,Carbendazole,Mercarzole
Target: Antifungal
ONO-7475
T8327
Synonym:
Target: Trk receptor, TAM Receptor
Borofalan(10B)
T26889
Synonym: L-4-Boronophenylalanine
Target: Others
Gemigliptin Tartrate(911637-19-9 free base)
T7369L
Synonym: LC15-0444 tartrate
Target: Proteasome, DPP-4
Ataquimast
T30190
Synonym:
Target: Others
CEP-40125
T26978
Synonym: RXDX-107
Target: DNA Alkylation
Berzosertib
T2669
Synonym: VX-970,VE-822
Target: ATM/ATR
Sparfosic Acid
T24818
Synonym: NSC224131,NSC-224131,Acide sparfosique,N-Phosphonacetyl-L-aspartate,NSC 224131
Target: Apoptosis
Aminoglutethimide
T1103
Synonym: DL-Aminoglutethimide,BA-16038,NSC-330915
Target: Aromatase
Valspodar
T17216
Synonym: PSC 833
Target: P-gp
Glufosfamide
T15390
Synonym: D 19575,Glucosylifosfamide mustard
Target: Others
LR-90
T11877
Synonym:
Target: Others
LY2874455
T2361
Synonym: LY 2874455,LY-2874455
Target: VEGFR, FGFR
Pimicotinib
T79157
Synonym: ABSK021,ABSK-021
Target: c-Fms, Others
MCI826
T16026
Synonym:
Target: P-gp, LTR
Trotabresib
T36395
Synonym: CC-90010
Target: Epigenetic Reader Domain
Cobolimab
T77149
Synonym: TSR-022,GSK4069889
Target: Others
Enloplatin
T68065
Synonym:
Target:
Avotaciclib
T39403
Synonym: BEY1107,Avotaciclib
Target: CDK
PHA-793887
T2113
Synonym: PHA 793887,PHA793887
Target: Apoptosis, CDK
Temsirolimus
T2145
Synonym: NSC 683864,CCI-779
Target: Apoptosis, mTOR, Autophagy
Alagebrium chloride
T7143
Synonym: ALT711
Target: Others, Endogenous Metabolite
Emitefur
T27259
Synonym: BOFA2,BOF A2,BOF-A2
Target: Others
Camizestrant
T11237
Synonym: Estrogen receptor antagonist 2
Target: Estrogen Receptor/ERR
Opnurasib
T40292
Synonym: NVP-JDQ443,JDQ-443,Opnurasib
Target: Ras
Tezepelumab
T77359
Synonym: Tezepelumab-ekko,MEDI 19929,AMG 157
Target: Others
Varlilumab
T76706
Synonym: CDX-1127
Target: TNF
Bezuclastinib
T60976
Synonym: CGT9486,PLX 9486
Target: c-Kit
Tenilsetam
T8583
Synonym: 3-(2-thienyl)- (9CI),Piperazinone
Target: Others
Calcium N5-methyltetrahydrofolate
T7598
Synonym: NSC173328
Target: Others, Antifolate
Tulmimetostat
T40199
Synonym: CPI-0209
Target: Histone Methyltransferase
GSK2636771
T2073
Synonym: GSK 2636771,GSK-2636771
Target: PI3K
Onvatilimab
T76696
Synonym: JNJ-61610588
Target: Others
Olaratumab
T76761
Synonym: LY3012207,IMC-3G3
Target: PDGFR
Abemaciclib
T2381
Synonym: CDK4/6 dual inhibitor,LY2835219
Target: CDK
LY2090314
T1755
Synonym:
Target: GSK-3
Felzartamab
T77006
Synonym: TJ-202,MOR-03087,MOR-202
Target: CD38
IMMH 010 maleate
T83970
Synonym: YPD-30 maleate
Target: PD-1/PD-L1
Lapatinib
T0078
Synonym: GSK572016,GW572016
Target: EGFR, Ferroptosis, Autophagy
Rosmantuzumab
T77750
Synonym: OMP-131R10
Target: Others
CD73-IN-3
T8875
Synonym: EX-A4254,LY-3475070
Target: CD73
Azeliragon
T2507
Synonym: TTP488
Target: Beta Amyloid, advanced glycation end products
ASP3026
T1962
Synonym: ASP 3026
Target: Apoptosis, ALK
Tefinostat
T17028
Synonym: CHR-2845
Target: HDAC
Ragifilimab
T77138
Synonym: INCAGN-01876,INCAGN-1876,CM-701
Target: TNF
Codrituzumab
T77440
Synonym: RG-7686,RO5137382,GC33
Target:
TAK-901
T2709
Synonym: TAK901
Target: JAK, CDK, Src, Aurora Kinase
1 2 3
Cat No. Product Name Synonyms Targets
T9715 Aplidine SARS-CoV , DNA/RNA Synthesis
Aplidine possesses antiviral activity against SARS-CoV-2(IC90 = 0.88 nM). Aplidine is a potent anti-cancer agent by targeting eukaryotic translation elongation factor 1 Alpha 2(EEF1A2, Kd = 80 nM).
T6S2384 Poliumoside Reductase
Poliumoside is a natural compound which exhibits significant inhibition of advanced glycation end product formation with IC50 value of 4.6-25.7 μM, it also exhibits great inhibitory effects on rat lens aldose reductase w...
T8242 Sabinene Others
Sabinene is a natural product that has antifungal and anti-inflammatory properties
TN1471 Cassiaside C Toralactone 9-O-β-D-gentiobioside Others , Endogenous Metabolite
Cassiaside C (Toralactone 9-O-β-D-gentiobioside), a naphthopyrone extracted from Cassia tora seeds, exhibits in vitro inhibitory activity against the formation of advanced glycation end products (AGE).
T10183 6-Methoxytricin Others
6-Methoxytricin is a flavonoid isolated from Artemisia iwayomogi. It is an inhibitor on aldose reductase (AR) and advanced glycation endproduct (AGE) formation activities (IC50s: 30.29 μM and 134.88 μM). 6-Methoxytricin ...
T12588 Pyridoxylamine pyridoxamine Endogenous Metabolite
Pyridoxylamine (pyridoxamine) is an inhibitor of advanced glycation end production (AGEs) and lipoxidation end products (ALEs).
T5565 Undecanedioic acid Others , Endogenous Metabolite
Undecanedioic acid has been found in parts of human aortas with advanced atherosclerotic lesions associated with intercellular matrix macromolecules and specifically with elastin.
TN2165 Rubrofusarin gentiobioside Rubrofusarin-6-O-beta-D-gentiobioside ERK , NF-κB , TGF-beta/Smad
Rubrofusarin gentiobioside (Rubrofusarin-6-O-beta-D-gentiobioside) can significantly decrease the expression of TGF-beta1 and fibronectin and NF-kappaB DNA binding activity, suggests that it has potential as a preventive...
TN2122 Quercetin 3-gentiobioside Quercetin-3-gentiobioside Reductase
Quercetin 3-gentiobioside (Quercetin-3-gentiobioside) is an inhibitor of AR and AGE formation and can be extracted from A. iwayomogi.Quercetin 3-gentiobioside inhibits the biological activity of aldose reductase (AR) and...
T13741 Isoviolanthin Others
Isoviolanthin reduces the migratory and invasive capacities of TGF-β1-treated HCC cells without cytotoxic effects on normal live cells and has potential as a therapeutic agent for the treatment of advanced-stage metastat...
T10619 Bromelain Apoptosis , Others
Bromelain is an anti-inflammatory drug derived from pineapple stem. It acts through down-regulation of plasma kininogen, degradation of advanced glycation end-product receptors, inhibition of Prostaglandin E2 expression,...
TN1042 Chebulic acid Others
Chebulic acid, a phenolcarboxylic acid compound isolated from Terminalia chebula, has potent anti-oxidant activity,which breaks the cross-links of proteins induced by advanced glycation end-products (AGEs) and inhibits t...
T4843 2,2-Dihydroxyacetic acid Formylformic acid,Glyoxylic acid monohydrate Others , Endogenous Metabolite
2,2-Dihydroxyacetic acid (Formylformic acid) is an intermediate in the glyoxalate cycle, which enables certain organisms to convert fatty acids to carbohydrates.2,2-Dihydroxyacetic acid has been found to be associated wi...
T19117 3-Deoxyglucosone 3-Deoxy-D-glucosone,2-keto-3-Deoxyglucose GPX , Glucagon Receptor
3-Deoxyglucosone(3-Deoxy-D-glucosone) is synthesized by the intermediate pathway of the melad and polyol reactions.3-Deoxyglucosone reacts rapidly with protein amino groups to form advanced glycosylated end proteins (AGE...
TN3972 Epimedokoreanin B Apoptosis , Others , Antibacterial
Epimedokoreanin B (EKB), an isoprenylated flavonoid isolated from Korean Epimedium, exhibited anticancer activity in human non-small cell lung cancer (NSCLC) A549 and NCI-H292 cells.Epimedokoreanin B also possesses anti-...
TN2894 3,5-Di-O-caffeoylquinic acid methyl ester HSV
3,5-Di-O-caffeoylquinic acid methyl ester exhibits potent inhibitory activities against the formation of advanced glycation end products (AGEs); it exhibits cytotoxicity actions against human cervix carcinoma HeLa cells....
T81905 Lucidin-ω-Me ether
Lucidin-ω-Me ether (Compound 2), extracted from Knoxia valerianoides roots, demonstrates inhibitory activity against the formation of advanced glycation end products (AGEs) with an IC50 of 62.79 μM in vitro [1].
T80950 Tricetin 7-O-glucoside
Chemical Compound 77298-67-0 exhibits high thermal stability and outstanding resistance to both corrosion and oxidation, suitable for extreme environmental conditions. Its melting point lies above 3500°C. The compound de...
TN6198 Mahanine
Mahanine has effects on the activation of the apoptotic pathway in human leukemia U937 cells, causes the mitochondrial membranes to lose their permeability, resulting in caspase-3 activation and apoptosis. Mahanine can r...
TN6059 Demethoxyfumitremorgin C
Demethoxyfumitremorgin C and tryprostatin B are fungal inhibitors of mammalian cell cycle progression at the G(2)/M transition. Demethoxyfumitremorgin C inhibits the proliferation of PC3 human prostate cancer cells via t...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-02881 RAGE Protein, Human, Recombinant Human HEK293
Receptor for Advanced Glycosylation End Products (RAGE, or AGER) is a member of the immunoglobulin super-family transmembrane proteins, as a signal transduction receptor which binds advanced glycation endproducts, certai...
TMPY-02927 RAGE Protein, Human, Recombinant (His) Human HEK293
Receptor for Advanced Glycosylation End Products (RAGE, or AGER) is a member of the immunoglobulin super-family transmembrane proteins, as a signal transduction receptor which binds advanced glycation endproducts, certai...
TMPY-01675 RAGE Protein, Mouse, Recombinant (His) Mouse HEK293
Receptor for Advanced Glycosylation End Products (RAGE, or AGER) is a member of the immunoglobulin super-family transmembrane proteins, as a signal transduction receptor which binds advanced glycation endproducts, certai...
TMPY-01716 RAGE Protein, Human, Recombinant (hFc) Human HEK293
Receptor for Advanced Glycosylation End Products (RAGE, or AGER) is a member of the immunoglobulin super-family transmembrane proteins, as a signal transduction receptor which binds advanced glycation endproducts, certai...
TMPY-02030 CD82 Protein, Human, Recombinant (His) Human HEK293
CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetras...
TMPY-00403 FGF-7/KGF Protein, Human, Recombinant (His) Human E. coli
Fibroblast growth factor 7 (FGF7) is a member of the fibroblast growth factor (FGF) family of proteins. FGF7 plays an important role in regulating the proliferation, migration, and differentiation of cells. FGF7 is of st...
TMPY-00778 DPP4/CD26 Protein, Human, Recombinant (hFc) Human HEK293
Dipeptidyl peptidase-4 (DPP4) or adenosine deaminase complexing protein 2 (ADCP 2) or T-cell activation antigen CD26 is a serine exopeptidase belonging to the S9B protein family that cleaves X-proline dipeptides from the...
TMPY-00221 DPP4/CD26 Protein, Mouse, Recombinant (hFc) Mouse HEK293
Dipeptidyl peptidase-4 (DPP4) or adenosine deaminase complexing protein 2 (ADCP 2) or T-cell activation antigen CD26 is a serine exopeptidase belonging to the S9B protein family that cleaves X-proline dipeptides from the...
TMPY-00122 DPP4/CD26 Protein, Human, Recombinant (His) Human HEK293
Dipeptidyl peptidase-4 (DPP4) or adenosine deaminase complexing protein 2 (ADCP 2) or T-cell activation antigen CD26 is a serine exopeptidase belonging to the S9B protein family that cleaves X-proline dipeptides from the...
TMPY-00779 DPP4/CD26 Protein, Human, Recombinant Human HEK293
Dipeptidyl peptidase-4 (DPP4) or adenosine deaminase complexing protein 2 (ADCP 2) or T-cell activation antigen CD26 is a serine exopeptidase belonging to the S9B protein family that cleaves X-proline dipeptides from the...
TMPY-01912 Cadherin 17/CDH17 Protein, Human, Recombinant (His) Human HEK293
Cadherin-17 or LI-cadherin is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Cadherin-17/LI-cadherin is a cadherin-like protein consisting of an extracellular r...
TMPY-05352 Cadherin 17/CDH17 Protein, Cynomolgus, Recombinant (hFc) Cynomolgus HEK293
Cadherin-17 or LI-cadherin is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Cadherin-17/LI-cadherin is a cadherin-like protein consisting of an extracellular r...
TMPY-02919 Cadherin 17/CDH17 Protein, Rat, Recombinant (His) Rat HEK293
Cadherin-17 or LI-cadherin is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Cadherin-17/LI-cadherin is a cadherin-like protein consisting of an extracellular r...
TMPY-03945 Latent TGF beta 1 Protein, Rat, Recombinant (His) Rat HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-04211 Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-00608 TGF beta 1 Protein, Rat/Mouse, Recombinant Mouse,Rat HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-02638 TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant Human,Rhesus,Cynomolgus,Canine CHO
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-02590 HMGB1 Protein, Mouse, Recombinant (hFc) Mouse HEK293
High-mobility group box 1 protein (HMGB1), also known as HMG-1 or amphoterin previously, is a member of the HMGB family consisting of three members, HMGB1, HMGB2, and HMGB3. HMGB1 is a DNA-binding nuclear protein, releas...
TMPY-01133 Latent TGF beta 1 Protein, Human, Recombinant (His) Human HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-00500 Latent TGF beta 1 Protein, Mouse, Recombinant (His) Mouse HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-01848 HMGB1 Protein, Human, Recombinant (aa 1-215, His) Human HEK293
High-mobility group box 1 protein (HMGB1), also known as HMG-1 or amphoterin previously, is a member of the HMGB family consisting of three members, HMGB1, HMGB2, and HMGB3. HMGB1 is a DNA-binding nuclear protein, releas...
TMPJ-01381 ANXA10 Protein, Human, Recombinant Human E. coli
Annexin A10 (ANXA10) contains four Annexin repeats and is a member of the Annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in sign...
TMPK-00249 TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
TNF-related apoptosis inducing ligand (TRAIL) is a potential antitumor protein known for its ability to selectively eliminate various types of tumor cells without exerting toxic effects in normal cells and tissues. TRAIL...
TMPK-00408 AXL Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpre...
TMPK-00410 AXL Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated Human HEK293
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpre...
TMPK-00248 TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi) Human HEK293
TNF-related apoptosis inducing ligand (TRAIL) is a potential antitumor protein known for its ability to selectively eliminate various types of tumor cells without exerting toxic effects in normal cells and tissues. TRAIL...
TMPK-00479 AGER Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
The receptor for advanced glycation end products (AGER) is an oncogenic transmembranous receptor up-regulated in various human cancers. AGER promotes proliferation, migration, and inhibits apoptosis of squamous cervical ...
TMPK-00082 IL-18BP Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggestin...
TMPK-00172 B7-H4 Protein, Human, Recombinant (His & Avi) Human HEK293
B7-H4, also known as B7x and B7S1, is a 50-80 kDa glycosylated member of the B7 family of immunomodulatory proteins.B7-H4 is up-regulated in several carcinomas in correlation with tumor progression and metastasis. A solu...
TMPK-00407 AXL Protein, Human, Recombinant (His & Avi) Human HEK293
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpre...
TMPK-00472 AXL Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpre...
TMPK-01045 IL-20RA Protein, Mouse, Recombinant (hFc) Mouse HEK293
IL-20RA was highly expressed in the tumor tissue of CRC and related to the advanced stage.IL-20RA was involved in regulating oncogenic and immune pathways and affecting the expression of genes related to cell proliferati...
TMPK-00491 IL-18BP Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggestin...
TMPK-00807 Osteopontin Protein, Mouse, Recombinant (His) Mouse HEK293
Secreted phosphoprotein 1 (SPP1) expression in TAMs isolated from lung adenocarcinoma tissues and PMA-treated THP-1 cells were measured. Macrophage polarization was identified by flow cytometric analysis. Cell migration ...
TMPK-01124 TEM1/CD248 Protein, Mouse, Recombinant (His) Mouse HEK293
Colorectal cancer (CRC) is one of the most common cancers worldwide usually diagnosed in the advanced stage. The serum concentration of tumor endothelial marker 1 (TEM1) was measured and correlated with clinicopathologic...
TMPK-00492 IL-18BP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated Cynomolgus HEK293
Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggestin...
TMPY-01584 PR-Set7 Protein, Human, Recombinant Human E. coli
KMT5A (known as PR-Set7/9, SETD8 and SET8), a member of the SET domain containing methyltransferase family specifically targeting H4K20 for methylation, has been implicated in multiple biological processes. Inhibition of...
TMPK-01321 TEM1/CD248 Protein, Canine, Recombinant (His) Canine HEK293
Colorectal cancer (CRC) is one of the most common cancers worldwide usually diagnosed in the advanced stage. The serum concentration of tumor endothelial marker 1 (TEM1) was measured and correlated with clinicopathologic...
TMPK-01191 TEM1/CD248 Protein, Human, Recombinant (His) Human HEK293
Colorectal cancer (CRC) is one of the most common cancers worldwide usually diagnosed in the advanced stage. The serum concentration of tumor endothelial marker 1 (TEM1) was measured and correlated with clinicopathologic...
TMPY-04206 FGF-7/KGF Protein, Mouse, Recombinant (His) Mouse E. coli
Fibroblast growth factor 7 (FGF7) is a member of the fibroblast growth factor (FGF) family of proteins. FGF7 plays an important role in regulating the proliferation, migration, and differentiation of cells. FGF7 is of st...
TMPY-04695 CCL4 Protein, Rat, Recombinant (His) Rat Yeast
CCL4 (C-C chemokine ligand 4), is a macrophage inflammatory protein with a chief effect in inflammation and immune-regulation, and was documented in cancer progression by promoting instability in the tumor environment. T...
TMPY-00646 CCL4 Protein, Human, Recombinant (His) Human Yeast
CCL4 (C-C chemokine ligand 4), is a macrophage inflammatory protein with a chief effect in inflammation and immune-regulation, and was documented in cancer progression by promoting instability in the tumor environment. T...
TMPY-06064 CD146/MCAM Protein, Human, Recombinant (His), Biotinylated Human HEK293
The CD146 antigen, also known as melanoma cell adhesion molecule (MCAM) and MUC18, is an integral membrane glycoprotein belonging to the immunoglobulin superfamily. CD146 contains the characteristic immunoglobulin-like d...
TMPJ-00292 CD36 Protein, Human, Recombinant (hFc) Human Human Cells
Platelet Glycoprotein 4 (CD36) is an integral membrane glycoprotein that has multiple physiological functions. It is broadly expressed on a variety of cell types including microvascular endothelium, adipocytes, skeletal ...
TMPY-02193 GOLPH2/GOLM1 Protein, Human, Recombinant (His) Human HEK293
Golgi membrane protein 1, also known as Golgi membrane protein GP73, Golgi phosphoprotein 2, and GOLM1, is a protein that belongs to the GOLM1 / CASC4 family. GOLM1 is widely expressed. It is highly expressed in the colo...
TMPY-01034 CD146/MCAM Protein, Human, Recombinant (His) Human HEK293
The CD146 antigen, also known as melanoma cell adhesion molecule (MCAM) and MUC18, is an integral membrane glycoprotein belonging to the immunoglobulin superfamily. CD146 contains the characteristic immunoglobulin-like d...
TMPY-00879 CD146/MCAM Protein, Human, Recombinant (hFc) Human HEK293
The CD146 antigen, also known as melanoma cell adhesion molecule (MCAM) and MUC18, is an integral membrane glycoprotein belonging to the immunoglobulin superfamily. CD146 contains the characteristic immunoglobulin-like d...
TMPY-02502 CD146/MCAM Protein, Mouse, Recombinant (His) Mouse HEK293
The CD146 antigen, also known as melanoma cell adhesion molecule (MCAM) and MUC18, is an integral membrane glycoprotein belonging to the immunoglobulin superfamily. CD146 contains the characteristic immunoglobulin-like d...
TMPY-01992 Kallikrein 8/KLK8 Protein, Human, Recombinant (His) Human HEK293
Kallikrein-8, also known as Neuropsin, Serine protease 19, Serine protease TADG-14, Tumor-associated differentially expressed gene 14 protein, and KLK8 is a secreted protein that belongs to the peptidase S1 family and Ka...
TMPY-02216 S100P Protein, Human, Recombinant Human E. coli
Protein S100-P, also known as Protein S100-E, S100 calcium-binding protein P, S100P and S100E, is a nucleus and cytoplasm protein that belongs to the S-100 family. S100P / S100E contains twoEF-hand domains. S100P protein...
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RAGE Protein, Human, Recombinant
TMPY-02881
Species: Human
Expression System: HEK293
RAGE Protein, Human, Recombinant (His)
TMPY-02927
Species: Human
Expression System: HEK293
RAGE Protein, Mouse, Recombinant (His)
TMPY-01675
Species: Mouse
Expression System: HEK293
RAGE Protein, Human, Recombinant (hFc)
TMPY-01716
Species: Human
Expression System: HEK293
CD82 Protein, Human, Recombinant (His)
TMPY-02030
Species: Human
Expression System: HEK293
FGF-7/KGF Protein, Human, Recombinant (His)
TMPY-00403
Species: Human
Expression System: E. coli
DPP4/CD26 Protein, Human, Recombinant (hFc)
TMPY-00778
Species: Human
Expression System: HEK293
DPP4/CD26 Protein, Mouse, Recombinant (hFc)
TMPY-00221
Species: Mouse
Expression System: HEK293
DPP4/CD26 Protein, Human, Recombinant (His)
TMPY-00122
Species: Human
Expression System: HEK293
DPP4/CD26 Protein, Human, Recombinant
TMPY-00779
Species: Human
Expression System: HEK293
Cadherin 17/CDH17 Protein, Human, Recombinant (His)
TMPY-01912
Species: Human
Expression System: HEK293
Cadherin 17/CDH17 Protein, Cynomolgus, Recombinant (hFc)
TMPY-05352
Species: Cynomolgus
Expression System: HEK293
Cadherin 17/CDH17 Protein, Rat, Recombinant (His)
TMPY-02919
Species: Rat
Expression System: HEK293
Latent TGF beta 1 Protein, Rat, Recombinant (His)
TMPY-03945
Species: Rat
Expression System: HEK293
Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His)
TMPY-04211
Species: Cynomolgus
Expression System: HEK293
TGF beta 1 Protein, Rat/Mouse, Recombinant
TMPY-00608
Species: Mouse,Rat
Expression System: HEK293
TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant
TMPY-02638
Species: Human,Rhesus,Cynomolgus,Canine
Expression System: CHO
HMGB1 Protein, Mouse, Recombinant (hFc)
TMPY-02590
Species: Mouse
Expression System: HEK293
Latent TGF beta 1 Protein, Human, Recombinant (His)
TMPY-01133
Species: Human
Expression System: HEK293
Latent TGF beta 1 Protein, Mouse, Recombinant (His)
TMPY-00500
Species: Mouse
Expression System: HEK293
HMGB1 Protein, Human, Recombinant (aa 1-215, His)
TMPY-01848
Species: Human
Expression System: HEK293
ANXA10 Protein, Human, Recombinant
TMPJ-01381
Species: Human
Expression System: E. coli
TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00249
Species: Human
Expression System: HEK293
AXL Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00408
Species: Human
Expression System: HEK293
AXL Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated
TMPK-00410
Species: Human
Expression System: HEK293
TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi)
TMPK-00248
Species: Human
Expression System: HEK293
AGER Protein, Cynomolgus, Recombinant (His)
TMPK-00479
Species: Cynomolgus
Expression System: HEK293
IL-18BP Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00082
Species: Human
Expression System: HEK293
B7-H4 Protein, Human, Recombinant (His & Avi)
TMPK-00172
Species: Human
Expression System: HEK293
AXL Protein, Human, Recombinant (His & Avi)
TMPK-00407
Species: Human
Expression System: HEK293
AXL Protein, Cynomolgus, Recombinant (His)
TMPK-00472
Species: Cynomolgus
Expression System: HEK293
IL-20RA Protein, Mouse, Recombinant (hFc)
TMPK-01045
Species: Mouse
Expression System: HEK293
IL-18BP Protein, Cynomolgus, Recombinant (His)
TMPK-00491
Species: Cynomolgus
Expression System: HEK293
Osteopontin Protein, Mouse, Recombinant (His)
TMPK-00807
Species: Mouse
Expression System: HEK293
TEM1/CD248 Protein, Mouse, Recombinant (His)
TMPK-01124
Species: Mouse
Expression System: HEK293
IL-18BP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
TMPK-00492
Species: Cynomolgus
Expression System: HEK293
PR-Set7 Protein, Human, Recombinant
TMPY-01584
Species: Human
Expression System: E. coli
TEM1/CD248 Protein, Canine, Recombinant (His)
TMPK-01321
Species: Canine
Expression System: HEK293
TEM1/CD248 Protein, Human, Recombinant (His)
TMPK-01191
Species: Human
Expression System: HEK293
FGF-7/KGF Protein, Mouse, Recombinant (His)
TMPY-04206
Species: Mouse
Expression System: E. coli
CCL4 Protein, Rat, Recombinant (His)
TMPY-04695
Species: Rat
Expression System: Yeast
CCL4 Protein, Human, Recombinant (His)
TMPY-00646
Species: Human
Expression System: Yeast
CD146/MCAM Protein, Human, Recombinant (His), Biotinylated
TMPY-06064
Species: Human
Expression System: HEK293
CD36 Protein, Human, Recombinant (hFc)
TMPJ-00292
Species: Human
Expression System: Human Cells
GOLPH2/GOLM1 Protein, Human, Recombinant (His)
TMPY-02193
Species: Human
Expression System: HEK293
CD146/MCAM Protein, Human, Recombinant (His)
TMPY-01034
Species: Human
Expression System: HEK293
CD146/MCAM Protein, Human, Recombinant (hFc)
TMPY-00879
Species: Human
Expression System: HEK293
CD146/MCAM Protein, Mouse, Recombinant (His)
TMPY-02502
Species: Mouse
Expression System: HEK293
Kallikrein 8/KLK8 Protein, Human, Recombinant (His)
TMPY-01992
Species: Human
Expression System: HEK293
S100P Protein, Human, Recombinant
TMPY-02216
Species: Human
Expression System: E. coli
Cat No. Product Name
L1000 Approved Drug Library

2863 compounds
A unique collection of 2863 approved drugs for high throughput screening (HTS) and high content screening (HCS);
L2192 Anti-Pancreatic Cancer Compound Library

2267 compounds
A unique collection of 2267 pancreatic cancer related compounds can be used in HTS and HCS;
L9200 Drug Repurposing Compound Library

4630 compounds
A unique collection of 4630 approved and clinical drugs for high throughput screening (HTS) and high content screening (HCS);
L6710 Anti-Inflammatory Traditional Chinese Medicine Compound Library

1260 compounds
A collection of 1260 TCM monomers with anti-inflammatory activity or targeting molecular therapeutic targets in inflammation, a powerful tool for drug discovery and mechanism study;
L2194 Anti-Colorectal Cancer Compound Library

1565 compounds
1565 compounds associated with colorectal cancer that can be used for high-throughput and high-content screening.
L1010 FDA-Approved & Pharmacopeia Drug Library

3158 compounds
3158 compounds from marketed drugs for high throughput screening (HTS) and high content screening (HCS);
L2196 Anti-Ovarian Cancer Compound Library

1888 compounds
A unique collection of 1888 compounds with anti-ovarian cancer therapeutic activity, can be used for anti-ovarian cancer drug discovery and pharmacological study;
TargetMol