suppress — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8575	ENFENAMIC ACID		Platelet aggregation
	Enfenamic acid is a platelet aggregation inhibitor and with antirheumatic.		Platelet aggregation
TP2281	P53 tumor suppressor fragment		Others
	p53 tumor suppressor fragment (232-240) is a peptide with the sequence H2N-Lys-Tyr-Met-Cys-Asn-Ser-Ser-Cys-Met-OH, MW= 1066.3. p53 is a tumor suppressor protein that in humans is encoded by the TP53 gene. p53 is crucial ...		Others
T25862	Neomyosuppressin	Thr-asp-val-asp-his-val-phe-leu-arg-phenh2,Dromyosuppressin,Neb-MS
	Neomyosuppressin is a myoinhibiting neuropeptide isolated from the grey fleshfly, Neobellieria bullata and Drosophila.
T79791	Immunosuppressant-1		Apoptosis
	Immunosuppressant-1 (Compound 31) suppresses T-cell proliferation triggered by anti-CD3/anti-CD28 co-stimulation and demonstrates immunosuppressive effects, including the induction of apoptosis in activated lymph node ce...		Apoptosis
T25683	Leucomyosuppressin	p-Glu-asp-val-asp-his-val-phe-leu-arg-phe-NH2
	Leucomyosuppressin, isolated from head extracts of the cockroach Leucophaea maderae, inhibits evoked transmitter release at the mealworm neuromuscular junction.
T5403	ULK-101		Autophagy
	ULK-101 is a potent and selective ULK1 inhibitor ( IC50s: 8.3/30 nM for ULK1/ULK2). It can suppress autophagy.		Autophagy
T21483	Tricaine methanesulfonate	MS-222	Others
	Tricaine methanesulfonate (MS-222) (TMS) is an anesthetic. Many hatcheries and research studies use TMS to immobilize fish for marking or transport and to suppress sensory systems during invasive procedures.		Others
T13522	7-Ketolithocholic acid	3α-Hydroxy-7-oxo-5β-cholanic acid	Endogenous Metabolite
	7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid) (3α-Hydroxy-7-oxo-5β-cholanic acid) is capable of absorption and serves to suppress the production of endogenous bile acid and the secretion of biliary cholester...		Endogenous Metabolite
T5802	Stearyl glycyrrhetinate		Antiviral , Antibacterial
	Stearyl glycyrrhetinate, the stearyl ester of 18-β-glycyrrhetinic acid, has been demonstrated to improve antiviral effects, reduce inflammation and suppress allergies in the pharmaceutical and cosmetic industry.		Antiviral , Antibacterial
TN2197	Secoisolariciresinol		TNF
	Secoisolariciresinol is an enterolignan precursor, it has antioxidant, and estrogen-like activities, it can significantly suppress triglyceride (TG) accumulation in 3T3-L1 adipocytes.		TNF
T8951	JTP 0819958 - HOIPIN-1		IκB/IKK
	JTP-0819958 is a selective linear ubiquitin chain assembly complex (LUBAC) inhibitor with an IC50 of 2.8 μM[1]. JTP-0819958 suppress LUBAC-mediated NF-kB activation in vitro[2].		IκB/IKK
TN1839	Kumatakenin	Jaranol,Kaempferol 3,7-O-dimethyl ether	Apoptosis , Anti-infection
	Kumatakenin can suppress >80% of the SOS-inducing activity of Trp-P-1 at <0.06 micromol/mL.		Apoptosis , Anti-infection
T7556	Fadrozole hydrochloride	CGS 16949A	Aromatase
	Fadrozole hydrochloride (CGS 16949A) is a model aromatase inhibitor that has been shown to suppress estrogen production in the ovaries of fish.		Aromatase
T4732	L-Carnosine	Karnozin,beta-Alanyl-L-histidine	Antioxidant , Endogenous Metabolite
	L-Carnosine (Karnozin) is is an antioxidant naturally found in skeletal muscle, brain tissue. It has the potential to suppress many of the biochemical changes that accompany aging.		Antioxidant , Endogenous Metabolite
TN3967	Epieriocalyxin A		ERK , BCL , ROS , Caspase , DNA/RNA Synthesis , JNK
	Epieriocalyxin A can suppress Caco-2 colon cancer cell growth. It could be a potential drug for colon cancer therapy in the future.		ERK , BCL , ROS , Caspase , DNA/RNA Synthesis , JNK
T8528	AC1903		TRP/TRPV Channel
	AC1903 is a specific inhibitor of TRPC5 channel, and has been shown to suppress severe proteinuria and prevent podocyte loss.		TRP/TRPV Channel
T9765	TJ-M2010-5		MyD88
	TJ-M2010-5 is a MyD88 inhibitor that binds to the TIR domain to interfere with its homodimerization and suppress MyD88 signaling. TJ-M2010-5 can be used in myocardial ischemia/reperfusion injury studies.		MyD88
T3391	Corosolic acid	Corsolic acid,2α-Hydroxyursolic acid,Glucosol,Colosolic acid,Colosic acid	FAK , Autophagy
	Corosolic acid (Colosic acid) contains anti-angiogenic activity that can suppress FAK signaling induced by angiopoietin-1. Corosolic acid exerts anticancer activities against HCC, colon, and colorectal Y cells, by induci...		FAK , Autophagy
TN1046	Murrayone		Others
	Murrayone, a coumarin-containing compound derived from M. paniculata, stands out as the most bioactive substance within this species, primarily due to its unique pharmacological attributes that notably suppress cancer me...		Others
TN1334	7-Methoxyrosmanol	7-O-Methylrosmanol	cAMP
	7-Methoxyrosmanol (7-O-Methylrosmanol) can effectively suppress FSK-induced luciferase expression under the control of the CRE, PEPCK-C and G6Pase gene promoters, it may contribute to its antihyperglycemic activity.		cAMP