inducer

ROS inducer 2 is a reactive oxygen species (ROS) inducer with antimicrobial activity. It inhibits Axonobactor.

ROS inducer 3 is a reactive oxygen species inducer, a fungicide used to study refractory plant bacterial diseases, and inhibits actinobacteria.

C EBPα inducer 1 (4(3H)-Quinazolinone, 6-fluoro-2-[(1E)-2-(5-nitro-2-furanyl)ethenyl]-3-phenyl-) is a potential inducer of myeloid differentiation via upregulation of C EBP.

Oct3 4-inducer-1 (2-(4-(4-methoxybenzyloxy)phenyl)acetonitrile) is an OCT3 4 inducer that promotes the expression and stabilization of OCT3 4 and enhances its transcriptional activity in a variety of human cells.

EBV lytic cycle inducer-1 is an iron chelate analogue that induces the lytic cycle of EBV.

Ferroptosisinducer-4 (Compound 5) is a phospholipid-based ferroptosis inducer featuring a terminal double bond at the sn-2 position. It exhibits significant cytotoxicity towards HT-1080 cells with an IC50 value of 18 μM. The toxicity mechanism involves the generation of lipid peroxides and oxidative damage to the cell membrane induced by the terminal double bond. Ferroptosisinducer-4 can be utilized in studies pertaining to the regulation of ferroptosis.

Interferon receptor inducer-1 Used in the treatment of a disorder in which the induction of interferon is involved. is an interferon (IFN) receptor inducer.

BiP inducer X (BIX) is a selective inducer of immunoglobulin heavy chain binding protein (BiP) GRP78 and an ER chaperone inducer. BiP inducer X prevents cell death in neurons and retinal cell lines.

Apoptosis Inducer 3 (Compound 3), a selective apoptosis triggering agent, induces both apoptosis and late-apoptosis phases, demonstrating cytotoxic effects against cancer cells [1].

Apoptosis Inducer 5, a lignan enantiomer extracted from Crataegus pinnatifida, demonstrates cytotoxic properties through inducing apoptosis and autophagy in Hep3B cells.

Autophagy Inducer 3 is a chemical compound that exhibits autophagy-induced activity, specifically inducing robust autophagic cell death in various cancer cells while sparing normal cells. This compound induces lethal autophagy through the formation of distinct autophagic vacuoles, LC3 puncta formation, and upregulation of signature autophagy markers such as Beclin and Atg family proteins [1].

ROS inducer 1 is a small molecule compound with bactericidal activity that inhibits the production of ROS in Xanthomonas axonopodis pv. citri (Xac), Xanthomonas oryzae pv. oryzae (Xoo) and Pseudomonas syringae pv. actinidiae (Psa). ROS inducer 1 induces ROS production in Xanthomonas cells and can be used to study bacterial infections in crops.

Ferroptosisinducer-5 (compound 20a) is an inducer of ferroptosis.

ABCA1 inducer 1, a non-lipid inducer of ABCA1, enhances ABCA1 expression in E3 4FAD mice expressing human APOE 3 4, augments the lipidation of apolipoprotein (APOE), and reverses various Alzheimer's disease (AD) phenotypes without increasing triglycerides.

ICD inducer-1 (Compound Re1) is an effective inducer of immunogenic cell death (ICD), targeting the endoplasmic reticulum (ER) and subsequently inhibiting ER phagocytosis. It shows promise for cancer research.

Autophagyinducer 7 (Compound SSA) serves as an inducer of autophagy (Autophagy) and apoptosis (Apoptosis). It stimulates autophagy by inhibiting Akt mTOR signaling and the expression of downstream proteins. Additionally, Autophagyinducer 7 suppresses DNA synthesis and causes G0-G1 cell cycle arrest, ultimately inhibiting the growth of tumor cells.

Ferroptosis apoptosis inducer-1 (compound 4d) acts as a dual inducer of both cell apoptosis (apoptosis) and iron-dependent cell death (ferroptosis). It promotes these processes by decreasing mitochondrial membrane potential and downregulating GPX4. Effective in vitro and in vivo, Ferroptosis apoptosis inducer-1 significantly inhibits the proliferation and metastasis of triple-negative breast cancer (TNBC), playing a crucial role in cancer research.

Codon readthrough inducer 1 contains pyrimidine bases and shows good readthrough activity.

Oct4 Inducer-2, an OCT4 inducer, sustains hiPSC formation by enhancing endogenous OCT4 expression and has applications in anti-aging research [1].

Apoptosis Inducer 4 (Compound 12b) is a compound that induces apoptosis and exhibits anticancer properties [1].

ROS inducer 6 (compound 9) acts as a reactive oxygen species (ROS) inducer by depleting intracellular glutathione, thereby functioning as an antitumor agent.

ROS-ERS inducer 2 (Complex 3f) promotes the generation of intracellular ROS, affects mitochondrial function, facilitates the release of damage-associated molecular patterns (DAMPs), induces immunogenic cell death (ICD), and activates endoplasmic reticulum stress (ERS). It plays a significant role in anti-hepatocellular carcinoma research.

Ferroptosisinducer 6 (6d) is an inducer of ferroptosis (ferroptosis) that exhibits potent potential for Type I II photodynamic therapy by inducing ROS production, oxidative stress, and mitochondrial damage. Additionally, it demonstrates antitumor activity.

Apoptosis Inducer 12 (Compound 3z) is a compound that promotes cell death via the mitochondrial pathway and is utilized in cancer research [1].