δ transcription factor

Transcription factor-IN-1 (Compound 4e) acts as an inhibitor of transcription factors. It exhibits anticonvulsant activity by antagonizing pentylenetetrazole (PTZ) with an ED50 of 34.5 mg/kg. Additionally, Transcription factor-IN-1 demonstrates antidepressant activity in a rat model.

NFAT Transcription Factor Regulator-1 is a synthesis inhibitor of IL-2 with an IC50 of 182 nM.

BRD32048 is the ETV1 transcription factor oncoprotein inhibitor.

Mithramycin A (Plicamycin), a DNA-binding antitumor antibiotic, is a selective specificity protein 1 (Sp1) inhibitor, which inhibits the growth of various cancers by decreasing Sp1 protein. Specificity protein 1 (Sp1) is a zinc-finger transcription factor that regulates multiple cellular functions and promotes tumor progression.

CADD522 (MFCD00167693) is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding with an IC50 of 10 nM, with antitumor activity

(+)-Syringaresinol shows antioxidant potential, it exhibits cytoprotective activity in cultured MCF-7 cells stressed by H2O2.

Retinoic acid-d5 (Vitamin A acid-d5) is the deuterium-labeled form of Retinoic acid. Retinoic acid is a natural RAR receptor agonist with an IC50 of 14 nM for RARα/β/γ and a Kd of 17 nM for PPARβ/δ. Retinoic acid, a metabolite of vitamin A, plays an important role in cell growth, differentiation and organ development. Retinoic acid acts by activating retinoic acid receptor alpha as an inhibitor of the transcription factor Nrf2.