prolyl

FG-2216 (YM-311) is a potent HIF-prolyl hydroxylase inhibitor for the PDH2 enzyme (IC50: 3.9 uM); orally bioavailable and induced reversible and significant Epo induction in vivo.

Prolyl-4-hydroxylase Inhibitor 11, a novel proline 4-hydroxylase inhibitor, shows protective effects against oxidative stress and Cu(II) toxicity in Chlorella vulgaris.

Prolyl Endopeptidase Inhibitor 1 is a potent inhibitor of prolyl endopeptidase (PEP; PE)(Ki : 15 nM) , has anti-amnesic effect.

Prolyl Hydroxylase inhibitor 1 is an orally active inhibitor of hypoxia inducible factor (HIF)-prolyl hydroxylase (PHD) (IC50 of 62.23 nM).

L-Leucyl-L-prolyl-L-prolyl-L-seryl-L-arginine is a peptide.

Phenylalanyl-prolyl-alanine is a neutral tripeptide.

L-Threonyl-L-lysyl-L-prolyl-L-arginyl-L-prolylglycyl-L-proline acetate is a useful organic compound for research related to life sciences and the catalog number is T64693.

Prolyl Endopeptidase Inhibitor 2 (Compound 8), a proline endopeptidase (PEP) inhibitor, exhibits an IC50 value of 31.11 μM. This compound is applicable in research related to neurodegenerative diseases [1].

Prolyl Endopeptidase is highly active in the brain and other tissues, where it degrades peptides containing proline, such as Substance P, neuropeptide Y, gonadotropin-releasing hormone, thyrotropin-releasing hormone, bradykinin, and angiotensin II. This enzyme is utilized in researching neuropsychiatric disorders including stress disorders, depression, and schizophrenia.

Z-Thioprolyl-Thioproline is a prolyl endopeptidase inhibitor derived from bovine brain, exhibiting inhibition constants of IC50 = 16 µM and Ki = 37 µM. This compound is utilized in the investigation of neurological disorders, including memory and cognitive disorders [1].

Z-Thioprolyl-Thiazolidine is a potent, specific inhibitor of bovine brain prolyl endopeptidase, demonstrating an inhibition constant (K i value) of 0.36 nM [1].

Prolylleucine (((Benzyloxy)carbonyl)-L-prolyl-D-leucine) is a dipeptide containing branched-chain amino acids.

Cyclo(isoleucylprolyl) is a useful organic compound for research related to life sciences and the catalog number is T130102.

Prolylvaline is used as a peptide with antibacterial properties.

5-Oxoprolyltryptophan is a bioactive chemical.

Glycylhydroxyprolylproline is a peptide.

Prolyldiketopiperazine B is a proline-based diketopiperazine.

Prolylglutamic acid is a bioactive chemical.

Prolylisoleucine is a derivative of isoleucine that is used in the biosynthesis of proteins.

L-Methionyl-L-glutamyl-L-histidyl-L-phenylalanyl-L-prolylglycyl-L-proline acetate is a useful organic compound for research related to life sciences and the catalog number is T64677.

L-Prolylglycine is a natural product for research related to life sciences. The catalog number is T65246 and the CAS number is 2578-57-6.

Prolylserine, a dipeptide, acts as a melanogenesis inhibitor in Mel-Ab cells by reducing microphthalmia-associated transcription factor (MITF) and tyrosinase expression, inducing phosphorylation of ERK, but not affecting cAMP response element-binding protein (CREB) [1].

Prolylrapamycin (21-Norrapamycin), a derivative of Rapamycin, exhibits antifungal activity. It effectively inhibits Candida albicans, Saccharomyces cerevisiae, and Fusarium oxysporum with MIC values ranging from 0.125 to 2 μg mL.

Oroxylin A 7-O-β-d-glucuronide and wogonoside should also be served as the chemical markers together with baicalin for the quality control of herbs and proprietary traditional Chinese medicine (PTCM) products of radix Scutellariae. Oroxylin A 7-O-glucuronide, Oroxin A, and Oroxin B can bind to the stem region of α-hemolysin (α-HL), when inhibiting the hemolytic activity of α-HL. Oroxylin A 7-O-glucuronide and 4', 5, 7-trihydroxy-6-methoxyflavone at a concentration of 100 microM inhibit 34 and 43% of total prolyl oligopeptidase (POP) activity, respectively.