Home Tools
Log in
Cart

Search Result

Search Results for " dose-dependent "

20

Compounds

Cat No. Product Name Synonyms Targets
T22282 Brr2-IN-3 Brr2 Inhibitor 9,Brr2 Inhibitor C9 Others
Brr2-IN-3 (Brr2 Inhibitor C9) is an allosteric inhibitor of the spliceosomal RNA helicase Brr2. Brr2 is implicated in autosomal-dominant retinitis pigmentosa (a group of progressive retinal degenerative disorders).
T77662 DJ4 Apoptosis
DJ4 induces a dose-dependent pro-apoptotic effect in the micromolar range.
T31675 Esaprazole C/63 Others
Esaprazole (C/63) has a dose - dependent cellular protective effect on the human gastric mucosa.
TN1182 11-​Keto-​beta-​boswellic acid 11-Keto-beta-boswellic acid Leukotriene Receptor , NF-κB , Lipoxygenase
11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor; it exerts dose dependent cardioprotective effect manifested by dose-dependent reduction in serum lactate dehydrogenas...
T6985 Benzo[a]pyrene 3,4-Benzopyrene Others
Benzo[a]pyrene (3,4-Benzopyrene) shows lung carcinogenicity in mice in a dose-dependent manner.
T19552 RPH-2823 Others
RPH-2823, a basic amphotericin analog, is diuretic, natriuretic, and potassium-preserving, inducing a dose-dependent decrease in SCC and an increase in trans-epithelial resistance.
T68174 Sergliflozin A SGLT
Sergliflozin A is a selective SGLT2 inhibitor that induces diabetes in a dose-dependent manner. It reduces hyperglycemia.
TN1071 Ophiopogonin D' Sirtuin , UGT
Ophiopogonin D' can activate SIRT1 in a dose-dependent manner. Ophiopogonin D' also noncompetitively inhibits UGT1A6 and UGT1A10.
TN7126 N-Vanillyloctanamide Others
N-Vanillyloctanamide is a capsaicinoid from the fruits of Capsicum annuum L. var. annuum. N-Vanillyloctanamide reduces the radical length of Lactuca sativa seedling, this inhibition being dose-dependent.
T30819 CGP 20376 CGP-20376,CGP20376
CGP 20376 is a benzothiazole compound, an anthelmintic, with dual dose-dependent modulation of in vitro effects on the respiratory burst of eosinophils and antifibrillatory properties.
T38562 AKN-028 FLT
AKN-028 is an orally active and potent FLT3 tyrosine kinase inhibitor ( IC 50 = 6 nM). AKN-028 causes dose-dependent inhibition of FLT3 autophosphorylation.
T6464 Detomidine hydrochloride MPV-253 AII,Domosedan,Detomidine HCl Adrenergic Receptor
Detomidine hydrochloride (MPV-253 AII) produce dose-dependent sedative and analgesic effects, mediatated by activation of α2 catecholamine receptors.
TN2058 Persicogenin Anti-infection
Persicogenin has anticancer, antimutagenic, and antileishmanial activities, it can inhibit the proliferation of mouse tsFT210 cancer cells, it mainly inhibits cell cycle at the G2/M phase in a dose-dependent manner.
T10276 AKT Kinase Inhibitor Akt
AKT Kinase Inhibitor is an Akt inhibitor with antitumor activity that selectively inhibits cell proliferation in a dose-dependent manner.
T6S1843 Tenacissoside I Tenacissimoside B Others
Tenacissoside I (Tenacissimoside B),Tenacissosides B, C and marsdenoside K inhibit the proliferation of Raji, NB4 and K562 cells in vitro significantly, in a dose and time dependent manner.
T3042 JAK2 Inhibitor V JAK2 Inhibitor V Z3,Z3 JAK
JAK2 Inhibitor V (JAK2 Inhibitor V Z3) is a novel specific inhibitor of Jak2, inhibiting Jak2-V617F and Jak2-WT autophosphorylation in a dose-dependent manner.
TN1558 N-Vanillyldecanamide Decylic acid vanillylamide Others
N-Vanillyldecanamide (Decylic acid vanillylamide), isolated from fruits of Capsicum annuum, significantly reduced free radical length in alfalfa seedlings in a dose-dependent manner.
T71746 Pincainide Others
Pincainide is a novel beta-aminoaniline that inhibits, in a dose-dependent manner, diseases caused by abnormal norepinephrine vascular smooth muscle function.
T2299 BMS-833923 XL-139 Apoptosis , Hedgehog/Smoothened , Smo
BMS-833923 (XL-139), an orally bioavailable Smoothened antagonist, inhibits BODIPY cyclopamine binding to SMO in a dose-dependent manner (IC50: 21 nM).
T36478 BI-6901 CCR
BI-6901 is a CCR10 antagonist. In a mouse model of DNFB exposure hypersensitivity, BI 6901 displays its anti-inflammatory response in a dose-dependent manner.
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
TargetMol