pd-l1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T9651	PD-1/PD-L1-IN-9		PD-1/PD-L1
	PD-1/PD-L1-IN-9, with an IC50 of 3.8 nM, is a potent and orally active inhibitor of the PD-1/PD-L1 interaction. It enhances the immune cells' ability to kill tumor cells and demonstrates significant antitumor activity in...		PD-1/PD-L1
T9616	PD-1/PD-L1-IN-10		PD-1/PD-L1
	PD-1/PD-L1-IN-10 is an orally active PD-1/PD-L1 inhibitor (IC50 of 2.7 nM) with potent anticancer efficacy.		PD-1/PD-L1
T3655	BMS-1	PD1-PDL1 inhibitor 1,PD-1/PD-L1 inhibitor 1	Apoptosis , PD-1/PD-L1
	BMS-1 (PD-1/PD-L1 inhibitor 1) is an inhibitor of the PD1-PD-L1 protein-protein interaction. It also acts as an immunomodulator. Programmed death ligand 1 (PD-L1) is a protein in humans that is encoded by the CD274 gene ...		Apoptosis , PD-1/PD-L1
T36900	PD-1/PD-L1-IN-NP19	PD-1/PD-L1-IN-NP19	PD-1/PD-L1
	PD-1/PD-L1-IN-NP19, a PD-1/PD-L1 inhibitor, exhibits an IC50 of 12.5 nM against the human PD-1/PD-L1 interaction, potentially activating the tumor immune microenvironment and contributing to its antitumor effects[1].		PD-1/PD-L1
T40112	PROTAC PD-1/PD-L1 degrader-1	PROTAC PD-1/PD-L1 degrader-1
	PROTAC PD-1/PD-L1 degrader-1, a Cereblon E3 ligand-based compound, is a PD-1/PD-L1 PROTAC that effectively inhibits the interaction between PD-1 and PD-L1 with an IC50 value of 39.2 nM. It successfully restores the suppr...
T36899	INCB086550	PD-1/PD-L1-IN-8	PD-1/PD-L1
	INCB086550 (PD-1/PD-L1-IN-8) (example 24) is a PD-1/PD-L1 inhibitor, with an IC50 <= 10 nM.		PD-1/PD-L1
T39591	Human PD-L1 inhibitor I	Human PD-L1 inhibitor I
	Human PD-L1 inhibitor I is a peptide ligand that specifically inhibits the interaction between human PD-L1 and human PD-1. It exhibits a KD value of 3.39 μM, indicating its binding affinity. The presence of Human PD-L1 i...
T36487	Evixapodlin	PD-1/PD-L1-IN 7,GS-4224	Antiviral , HBV , PD-1/PD-L1
	Evixapodlin (PD-1/PD-L1-IN 7) is a human PD-1/PD-L1 protein/protein interaction inhibitor (IC50: 0.213).Evixapodlin has anticancer and antiviral activities.		Antiviral , HBV , PD-1/PD-L1
T39589	Human PD-L1 inhibitor III	Human PD-L1 inhibitor III
	Human PD-L1 inhibitor III is a human PD-L1 inhibitor.
T39590	Human PD-L1 inhibitor II	Human PD-L1 inhibitor II
	Human PD-L1 inhibitor II is a potent PD-L1 inhibitor with anti-cancer activity.
T39588	Human PD-L1 inhibitor IV	Human PD-L1 inhibitor IV
	Human PD-L1 inhibitor IV is a polypeptide compound that competitively inhibits the human PD-1 protein. It has a Kd value of 1.38 μM and effectively blocks the interaction between hPD-1 and hPD-L1.
T12380	PD-1/PD-L1-IN 5 TFA	PD-1/PD-L1-IN 5	Others
	PD-1/PD-L1-IN 5 is an inhibitor of PD-1/PD-L1 protein/protein interaction (IC50 of ≤100 nM).		Others
T3146	BMS-202	PD1-PDL1 inhibitor 2,PD-1/PD-L1 inhibitor 2	Apoptosis , PD-1/PD-L1
	BMS-202 (PD1-PDL1 inhibitor 2) is an inhibitor of the PD-1 (Programmed death- 1) /PD-Ll (Programmed death-ligand 1) protein/protein interaction.		Apoptosis , PD-1/PD-L1
T4696	BMS202 hydrochloride (1675203-84-5(free base))	PD-1/PD-L1 inhibitor 2 hydrochloride	PD-1/PD-L1
	BMS202 hydrochloride (1675203-84-5(free base)) (PD-1/PD-L1 inhibitor 2 hydrochloride) is a small-molecule PD-1/PD-L1 interaction inhibitor (IC50: 18 nM). Biophysical studies demonstrate that BMS202 binds directly to PD-L...		PD-1/PD-L1
T26859	BMS-8		PD-1/PD-L1
	BMS-8 is a novel inhibitor of the PD-1/PD-L1 interaction (IC50: 7.2 μM) by binding directly to PD-L1 and inducing the formation of PD-L1 homodimers.		PD-1/PD-L1
TP1463	PD-1/PD-L1-IN 3 TFA (1629654-95-0 free base)	PD-1/PD-L1-IN 3 TFA
	PD-1/PD-L1-IN 3 TFA inhibits the binding of human PD-1 to PD-Ll with an IC50 of 9 nM.
T72670	PD-1/PD-L1-IN-13
	PD-1/PD-L1-IN-13 is a potent immune checkpoint PD-1/PD-L1 inhibitor with an IC50 value of 10.2 nM for PD-1/PD- L1 interaction.PD-1/PD-L1-IN-13 promotes CD8+ T-cell activation and delays tumour growth in a Hepa1-6 homozyg...
T62501	PD-1/PD-L1-IN-17
	PD-1/PD-L1-IN-17 (Compound P20) is a potent PD-1/PD-L1 inhibitor (IC50: 26.8 nM). PD-1/PD-L1-IN-17 is a promising lead compound for the development of inhibitors of PD-1/PD-L1 interactions. -17 has potential for cancer d...
T72675	PD-1/PD-L1-IN-23
	PD-1/PD-L1-IN-23 is a potent, orally active ester prodrug of L7, a benzooxadiazole derivative, and functions as an inhibitor of PD-1/PD-L1. It has been biologically evaluated for its inhibitory effects on PD-L1, demonstr...
T63614	PD-1/PD-L1-IN-15
	PD-1/PD-L1-IN-15 is a potent inhibitor of PD-1/PD-L1 (IC50: 60.1 nM) and has shown investigational potential for tumor immunotherapy.