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IBI-363
(Synonyms: IBI363) Copy Product Info
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Synonyms: IBI363
Catalog No. T9901A-2415 Copy Product Info
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IBI-363 is a PD-1/IL-2α-bias bispecific fusion protein targeting PD-1 and the IL-2 signaling pathway. It blocks PD-1/PD-L1-mediated immune suppression while selectively modulating IL-2 signaling to enhance T-cell activation and antitumor immune responses. IBI-363 can be used in cancer immunotherapy research, T-cell activation studies, immune checkpoint regulation, and immune activation of cold tumors.
IBI-363
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| Description | IBI-363 is a PD-1/IL-2α-bias bispecific fusion protein targeting PD-1 and the IL-2 signaling pathway. It blocks PD-1/PD-L1-mediated immune suppression while selectively modulating IL-2 signaling to enhance T-cell activation and antitumor immune responses. IBI-363 can be used in cancer immunotherapy research, T-cell activation studies, immune checkpoint regulation, and immune activation of cold tumors. |
| Synonyms | IBI363 |
| Reactivity | Human |
| Application | Functional assay |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | PD-1 & IL-2α |
| Molecular Weight | 112 kDa (Predicted) |
| Relative Density. | no data available |
| Storage | -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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