gal

GAL-021 an intravenous BKCa-channel blocker.

Neu5Acα(2-3)Galβ MP glycoside is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

Galβ(1-3)GlcNAcβ(1-3)Galβ(1-4)Glc-β-pNP is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

Phenyl 2,4,6-tri-O-acetyl-3-O-allyl-β-D-thiogalactopyranoside (Gal[246Ac,3All]-β-SPh) is a biochemical reagent employed in glycobiology research. Glycobiology focuses on the study of sugar structures, synthesis, biology, and evolution. It encompasses carbohydrate chemistry, glycan synthesis and degradation enzymology, protein-glycan interactions, and the role of glycans in biological systems, closely linking basic research, biomedicine, and biotechnology.

ST3 beta-Gal alpha-2,3-Sialyltransferase 2 (EC:2.4.3.4, ST3GAL2) catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates.

ST3 beta-Gal alpha-2,3-Sialyltransferase 6 (EC:2.4.99., ST3GAL6; SIAT10, Type 2 lactosamine alpha-2,3-sialyltransferase) is responsible for transferring sialic acid from activated cytidine 5'-monophospho-N-acetylneuraminic acid to terminal positions on sialylated glycolipids (gangliosides) or to N- or O-linked glycans on glycoproteins. This enzyme plays a significant role in cancer.

ST6 GalSialyltransferase1 (EC:2.4.3.1, ST6GAL1) catalyzes the transfer of sialic acid from CMP-sialic acid to substrates containing galactose.

ST6 GalSialyltransferase2 (EC:2.4.3.1, ST6GAL2) catalyzes the transfer of sialic acid from CMP to oligosaccharide substrates. It plays a significant role in schizophrenia research.

Galβ(1-4)Glc-β-MP is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

Gal[26Bn]β(1-4)Glc[236Bn]-β-MP is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

Gal[246Bn]β(1-4)Glc[236Bn]-β-MP is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

Galβ(1-3)[Neu5Acα(2-6)]GlcNAc-β-pNP is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

β-Galactosidase (GAL) is a glycoside hydrolase that hydrolyzes the β-glycosidic bond formed between galactose and its organic part, and naturally catalyzes the hydrolysis of the galactosidic bond in oligosaccharides and disaccharides for the degradation of lactose and the production of low-lactose and lactose-free lactose products that are beneficial to lactose intolerant patients.

4-Nitrophenyl α-D-galactopyranoside (PNP-alpha-D-Gal) is an artificial substrate of 4-nitrophenyl (pNP) glycopyranoside used for detecting α-galactosidase activity. The amount of released pNP increases significantly when PNP-alpha-D-Gal is used as a substrate.

X-alpha-Gal is a substrate for alpha-galactosidase. It is used for differentiating alpha-galactosidase-positive strains of yeast.

Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH (Fmoc-Ser(Ac3AcNH-α-Gal)-OH) is an anti-tumor drug.

ZINC77292789 (Fmoc-Thr[GalNAc(Ac)3-α-D]-OH) is a reagent for the preparation of a synthetic MUC1 Glycopeptide Bearing βGalNAc-Thr as a Tn antigen isomer which induces the antibody production against tumor cells. ZINC77292789 is a starting material to make trimeric MUC1 immunodominant motif antigen-based anti-cancer vaccine candidates.

Gal[246Bn,3All]-β-SPh is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

GB1107 is an effective and selective Galectin-3 inhibitor with a Kd of 37 nM.

ONPG (2-Nitrophenyl β-D-galactopyranoside) is a colorimetric and spectrophotometric substrate used to detect β-galactosidase activity.

Lactulose (Lactulosum) , a synthetic disaccharide , is used in the treatment of constipation and hepatic encephalopathy.

GAL-021 sulfate is a BKCa channel blocker that inhibits the analgesic effects of opioids and is used in the study of respiratory control diseases.

C2-Gal-Dox is a galactose conjugate known for its high cytotoxicity and ability to inhibit the growth of various cancer cells.

Gal-ARV-771 is a PROTAC prodrug, modified with galactose, based on ARV-771. It is activated in senescent cancer cells that express SA-β-Gal, thereby releasing ARV-771. Through the ubiquitin-proteasome pathway, Gal-ARV-771 induces selective degradation of the BRD4 protein in senescent cells and promotes apoptosis (apoptosis) of these cancer cells.