Hepatitis

Hepatitis Virus C NS3 Protease Inhibitor 2, a peptide inhibitor derived from a product targeting the NS3 protease of the hepatitis C virus (HCV), exhibits inhibitory activity with a Ki value of 41 nM.

The hepatitis B virus (HBV) core protein has been found in the nucleus, the cytoplasm, or both of HBV-infected hepatocytes. nuclear localization of the HBV core protein is negatively regulated by phosphorylation during the cell cycle.

Oglufanide (H-Glu-Trp-OH) is a naturally occurring thymic immunomodulator that inhibits vascular endothelial growth factor (VEGF).

Hepatitis C Virus S5A/5B, a synthetic peptide substrate, replicates the NS5A/5B junction of the nonstructural protein (NS), serving as the substrate for examining HCV NS3 protease activity [1].

Hepatitis B Virus Receptor Binding Fragment (hepatitis B peptide 4980), a synthetic peptide analog, specifically binds to Hep G2 cells and is a potential immunogen expected to induce protective antibodies through the attachment blockade pathway of virus neutralization [1] [2].

Hepatitis B Virus Pre-S Region (120-145) is a preS2 peptide that effectively blocks the attachment of single-chain Fv fragment (scFv) or IgG to recombinant Hepatitis B surface antigen (r-HBsAg) [1].

[Ala127] Hepatitis B Virus Pre-S Region (120-131) is a peptide with the sequence MQWNSTAFHQT, potentially useful for studies on activity enhancement [1].

HBcAg (core antigen) is a hepatitis B viral protein. It is an indicator of active viral replication; this means the person infected with Hepatitis B can likely transmit the virus on to another person.

H-Asp(otbu)-otbu HCl is an aspartic acid derivative that may be used to study comparative neurological function and metabolic disorders of non-alcoholic hepatitis.

Alisporivir (Debio-025) is a cyclophilin A inhibitor that disrupts the interaction between CypA and NS5A. It exhibits anti-hepatitis C virus (HCV) activity in vivo and in vitro, inhibits the replication of MERS and SARS coronaviruses, and promotes antigen-specific CD8(+) T cell activation.

Cyclosporin B is an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. Cyclosporin B displays antiviral properties, inhibiting the entry of hepatitis B into hepatocytes. Cyclosporin B also

Bulevirtide, also known by its developmental code name Myrcludex B, is a synthetic lipopeptide inhibitor of the sodium taurocholate cotransporting polypeptide (NTCP) that effectively inhibits the cellular entry of both hepatitis B virus (HBV) and hepatitis D virus (HDV) into hepatocytes, even in cases of compensated cirrhosis, showing significant potential for the treatment of chronic hepatitis D.

PQDVKFP, a synthetic peptide, identifies antigenic domains within the core protein of the hepatitis C virus (HCV) [1].

HCV-1 e2 Protein (554-569), a primary antigenic region within the Hepatitis C Virus envelope 2 (e2) protein, contains a putative N-glycosylation site believed to affect immune recognition of e2 [1].

HCV-1 e2 Protein (484-499) is a 16-amino acid peptide derived from the envelope 2 protein of the hepatitis C virus, identified in the sera of individuals possessing antibodies to HCV [1].

HCV Peptide (131-140) is a research-grade peptide used in studying the hepatitis C virus (HCV) [1].

HCV Peptide (35-44), a core protein of Hepatitis C Virus at positions 35 to 44, functions as an HLA-A2-restricted CTL epitope and inhibits NK cell activity through the KIR2DL2/3 receptor and synergistically through the CD94:NKG2A receptor [1].

HCV Peptide (257-266) is a peptide employed in hepatitis C virus (HCV) research [1].

HCV Core Protein (59-68) is a peptide containing residues 59-68 from the core protein of the Hepatitis C virus (HCV) [1].

HBV Seq2 aa:28-39, a Hepatitis B surface antigen (HBsAg) peptide, specifically binds to Major Histocompatibility Complex (MHC) class I molecules, as evidenced in sources [1] [2].

HBV Seq2 aa:208-216, a CD8 epitope peptide derived from HBsAg, is investigated within the context of the Large envelope protein from the Hepatitis B virus [1].

HBV Seq2 aa:179-186, a novel epitope located on the hepatitis B virus surface antigen, effectively serves as a motif for CTL response within the H-2b system following in vitro restimulation of primed T cells [1].

HBV Seq1 aa:93-100 is a peptide fragment of the hepatitis B virus (HBV) core antigen spanning amino acids 93 to 100 [1].

HBV Seq1 aa:63-71 is a fragment of the hepatitis B virus (HBV) [1].