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Search Result

Search Results for " antineoplastic "

545

Compounds

72

Natural Products

1

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T31424 DIBA PD022551,NSC 654077,DIBA-1,PD-22551,DIBA (Antineoplastic)
DIBA is an ER zinc finger inhibitor that inhibits ligand-dependent and non-dependent cell growth in TAM resistant breast cancer in vitro and in vivo.
T9262 MAT2A inhibitor 4 Others , Methionine Adenosyltransferase (MAT)
MAT2A Inhibitor 4 acts as an inhibitor targeting the catalytic subunit of methionine S-adenosyltransferase-2 (MAT2A), offering potential utility in cancer research.
T7747 Datelliptium chloride hydrochloride DNA/RNA Synthesis
Datelliptium chloride hydrochloride is a DNA-intercalating agent derived from ellipticine. with anti-tumor activities.
T13386 Zandelisib PI3K
Zandelisib is an inhibitor of phosphatidylinositol 3-kinase (PI3K)(p110δ, IC50 of 3.5 nM), and with antineoplastic activity.
T12401 Pemigatinib INCB054828 FGFR
Pemigatinib (INCB054828) is an orally active, selective inhibitor of FGFR(IC50s of 0.4 nM, 0.5 nM, 1.2 nM, 30 nM for FGFR1, FGFR2, FGFR3, FGFR4, respectively).
T1564 Cisplatin cis-Diaminodichloroplatinum,CDDP DNA Alkylator/Crosslinker , Ferroptosis , DNA/RNA Synthesis , Autophagy
Cisplatin (CDDP) is a DNA cross-linking agent. Cisplatin has antitumor activity and inhibits DNA synthesis by forming DNA adducts in cancer cells. Cisplatin also activates iron death and induces autophagy.
T9473 4SC-203 FLT
4SC-203 is a multikinase inhibitor with potential antineoplastic activity. 4SC-203 selectively inhibits FMS-related tyrosine kinase 3 (FLT3/STK1), FLT3 mutated forms, and vascular endothelial growth factor receptors (VEG...
T1307 Carmofur HCFU Nucleoside Antimetabolite/Analog , Virus Protease , SARS-CoV , DNA/RNA Synthesis
Carmofur (HCFU) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer. Carmofur has been known to induce leukoencephalopathy.
T8003 Methotrexate disodium Apoptosis , Dehydrogenase , DNA/RNA Synthesis , Antifolate
Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor
T12317 Orelabrutinib ICP-022 BTK
Orelabrutinib (ICP-022) is an orally active and irreversible inhibitor of Bruton's tyrosine kinase (BTK).
T15012 Crolibulin EPC2407 Microtubule Associated
Crolibulin (EPC2407) is an inhibitor of small molecule tubulin polymerization.
T1921 Alpelisib BYL-719 PI3K
Alpelisib (BYL-719) is a PI3Kα inhibitor (IC50=5 nM) with selective, potent, and oral activity. Alpelisib inhibits PI3Kβ/γ/δ with low activity (IC50=250/290/1200 nM). Alpelisib has antitumor activity and is targeted to P...
T23256 RS-25344 hydrochloride PDE
RS 25344 hydrochloride is a phosphodiesterase (PDE) 4 inhibitor
T4552 Fursultiamine Diteftin,Judolor,Alinamin F Others
Fursultiamine (Alinamin F) is a disulfide derivative of thiamine, or an allithiamine. It has potential uses in the treatment of vitamin B1 deficiency.
T1120 Dacarbazine Imidazole Carboxamide,DTIC-Dome Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
Dacarbazine (DTIC-Dome) is an antineoplastic agent. It has significant activity against melanomas.
T7539 O6-Benzylguanine Apoptosis , DNA Alkylation , DNA/RNA Synthesis
O6-Benzylguanine is a guanine analog with antineoplastic activity,and is a potent O6-alkylguanine DNA alkyltransferase (AGT) inactivator.
T5462 Almonertinib HS-10296 EGFR
Almonertinib (HS-10296) is an inhibitor of EGFR activation mutation and tolerant mutation of EGFR T790M, which has only limited activity against wild-type EGFR.
T20681 Estramustine NSC-89201,NSC 89201,LEO 275,LEO275,NSC89201,LEO-275 Microtubule Associated
Estramustine (LEO-275) is a nitrogen mustard linked to estradiol, usually as phosphate. Estramustine has been used to treat prostatic neoplasms; also has radiation protective properties. Estramustine is selectively taken...
T5675 Almonertinib hydrochloride HS-10296 hydrochloride EGFR
Almonertinib hydrochloride (HS-10296 hydrochloride) is a small molecule inhibitor of EGFR-activating mutations and T790M-resistant mutation with limited activity against wild-type EGFR.
T6410 Bexarotene Ro 26-4455,Targretin,LGD1069 Retinoid Receptor , Autophagy
Bexarotene (LGD1069) is a retinoid analogue that is used to treat the skin manifestations of cutaneous T cell lymphoma (CTCL).
T1199 Mitotane Mitotan,o,p'-DDD,NCI-C04933,2,4′-DDD Apoptosis , AChR
Mitotane (NCI-C04933) is a derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors a...
T1485 Methotrexate NCI-C04671,WR19039,Amethopterin,CL14377 Apoptosis , Dehydrogenase , DNA/RNA Synthesis , Antifolate
Methotrexate (WR19039) is a folate analog, an inhibitor of the dihydrofolate reductase DHFR. Methotrexate has antimetabolic, antitumor, and immunosuppressive activities, and is commonly used in rheumatoid arthritis and v...
T1241 Altretamine Hexamethylmelamine,NSC13875,RB-1515,ENT-50852,WR-95704 DNA Alkylator/Crosslinker , DNA Alkylation
Altretamine (ENT-50852) is an alkylating agent with antineoplastic activity.
T9445 Vepafestinib c-RET
Vepafestinib is a RET inhibitor with potential antineoplastic activity[1].
T26972 Cedazuridine (4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine DNA Methyltransferase
Cedazuridine ((4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine) is an oral inhibitor of cytidine deaminase with antineoplastic properties.
T7660 IDO inhibitor 1 Indoleamine 2,3-Dioxygenase (IDO)
IDO inhibitor 1 is an potent inhibitor of indoleamine-2,3 dioxygenase (IDO) ( IC50 <100 nM).with potential immunomodulating and antineoplastic activities.
T20048 Vidarabine phosphate Antiviral
Vidarabine phosphate is an adenosine monophosphate analog. It is the monophosphate ester of VIDARABINE. It also has antiviral and possibly antineoplastic properties.
T0244 Tilorone dihydrochloride Influenza Virus , HIF/HIF Prolyl-Hydroxylase , IFNAR
Tilorone dihydrochloride is an orally active interferon inducer, and has antineoplastic and anti-inflammatory actions.
T17172 Trofosfamide Antibacterial
Trofosfamide is a derivative of oxazaphosphorine with antineoplastic potency.
T1250 Thio-TEPA Tiofosyl,Triethylenethiophosphoramide,Tiofosfamid DNA Alkylator/Crosslinker , DNA Alkylation , Antibacterial , Antibiotic
Thio-TEPA (Tiofosyl) is a polyfunctional, organophosphorus alkylating agent with antineoplastic activity.
T3389 Antitumor agent-21 TRX818 Others
Antitumor agent-21 (TRX818) is an orally bioavailable agent with potential antineoplastic and anti-vasculogenic mimicry (VM) activities.
T6153 Icotinib BPI-2009,BPI-2009H,Conmana EGFR
Icotinib (Conmana) is an orally available quinazoline-based inhibitor of epidermal growth factor receptor (EGFR), with potential antineoplastic activity.
T2492 Perifosine NSC 639966,D21266,KRX-0401 Apoptosis , Akt , Autophagy
Perifosine (KRX-0401) is an oral-active, alkyl-phosphocholine Akt inhibitor with potential antineoplastic activity.
T2510 Galunisertib LY2157299 TGF-beta/Smad
Galunisertib (LY2157299) is an orally available inhibitor of TGFβRI kinase (IC50: 56 nM) with potential antineoplastic activity.
T1961 Vistusertib AZD2014 Apoptosis , Akt , PI3K , S6 Kinase , mTOR , Autophagy
Vistusertib (AZD2014) is an orally bioavailable inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity.
T2243 Serdemetan JNJ-26854165 Apoptosis , Mdm2 , E1/E2/E3 Enzyme , p53
Serdemetan (JNJ-26854165) is an orally bioavailable HDM2 antagonist with potential antineoplastic activity.
T2666 Taladegib LY2940680 Hedgehog/Smoothened , Smo
Taladegib (LY2940680) is an orally bioavailable small molecule antagonist of the Hedgehog (Hh)-ligand cell surface receptor smoothened (Smo) with potential antineoplastic activity.
T8945L AST5902 mesylate(2412155-74-7 free base) Drug Metabolite
AST5902 mesylate is principal metabolite of Alflutinib in vivo. AST5902 mesylate exerts antineoplastic activity.
T8151 Mobocertinib tak788 EGFR
Mobocertinib (tak788) is a potent inhibitor of epidermal growth factor receptor (EGFR) and an antineoplastic agent
T6121 Tepotinib EMD-1214063,MSC2156119 Trk receptor , c-Met/HGFR , TAM Receptor
Tepotinib (EMD-1214063) is an inhibitor of MET tyrosine kinase with potential antineoplastic activity.
T3091 Carmustine bis-chloroethylnitrosourea,Nitrumon,Gliadel,BCNU,BiCNU,Carmubris DNA Alkylator/Crosslinker , DNA Alkylation
Carmustine (bis-chloroethylnitrosourea) is a cell-cycle phase nonspecific alkylating antineoplastic agent.
T26889 Borofalan(10B) L-4-Boronophenylalanine Others
Borofalan(10B) (L-4-Boronophenylalanine) echibits antineoplastic effects. Borofalan can be used in studies on recurrent or locally advanced head and neck cancer.
T3677 GSK2879552 GSK2879552 2HCl Histone Demethylase
GSK2879552 is a selective, orally bioavailable, irreversible, mechanism-based inactivator of lysine-specific demethylase 1 (LSD1)/corepressor, with potential antineoplastic activity.
T6131 Pimasertib AS703026,MSC1936369B,SAR 245509 MEK
Pimasertib (AS703026) is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity.
T6487 Encorafenib LGX818 Raf
Encorafenib (LGX818) is an orally available mutated BRaf V600E inhibitor(IC50=0.3 nM) with potential antineoplastic activity.
T2394 Pixantrone dimaleate BBR-2778,Pixantrone Maleate,BBR 2778 dimaleate Topoisomerase
Pixantrone dimaleate (Pixantrone Maleate) (BBR 2778 dimaleate) is an experimental antineoplastic drug.
T0676 Hydroxyurea Hydroxycarbamide,nsc32065,nci-c04831 Apoptosis , HIV Protease , DNA/RNA Synthesis , Autophagy
Hydroxyurea (Hydroxycarbamide), an antineoplastic agent, inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.
T2339 Apalutamide ARN-509 Androgen Receptor , GABA Receptor
Apalutamide (ARN-509) is a small molecule and androgen receptor (AR) antagonist with potential antineoplastic activity.
T1759 OTSSP167 MELK inhibitor,OTS167 MELK
OTSSP167 (OTS167) is an orally available inhibitor of maternal embryonic leucine zipper kinase (MELK) with potential antineoplastic activity.
T8495 Alobresib Vorolanib,GS-5829 Epigenetic Reader Domain
Alobresib (Vorolanib) is an inhibitor of BET bromodomain,is an antineoplastic drug candidate.

Compounds

DIBA
T31424
Synonym: PD022551,NSC 654077,DIBA-1,PD-22551,DIBA (Antineoplastic)
Target:
MAT2A inhibitor 4
T9262
Synonym:
Target: Others, Methionine Adenosyltransferase (MAT)
Datelliptium chloride hydrochloride
T7747
Synonym:
Target: DNA/RNA Synthesis
Zandelisib
T13386
Synonym:
Target: PI3K
Pemigatinib
T12401
Synonym: INCB054828
Target: FGFR
Cisplatin
T1564
Synonym: cis-Diaminodichloroplatinum,CDDP
Target: DNA Alkylator/Crosslinker, Ferroptosis, DNA/RNA Synthesis, Autophagy
4SC-203
T9473
Synonym:
Target: FLT
Carmofur
T1307
Synonym: HCFU
Target: Nucleoside Antimetabolite/Analog, Virus Protease, SARS-CoV, DNA/RNA Synthesis
Methotrexate disodium
T8003
Synonym:
Target: Apoptosis, Dehydrogenase, DNA/RNA Synthesis, Antifolate
Orelabrutinib
T12317
Synonym: ICP-022
Target: BTK
Crolibulin
T15012
Synonym: EPC2407
Target: Microtubule Associated
Alpelisib
T1921
Synonym: BYL-719
Target: PI3K
RS-25344 hydrochloride
T23256
Synonym:
Target: PDE
Fursultiamine
T4552
Synonym: Diteftin,Judolor,Alinamin F
Target: Others
Dacarbazine
T1120
Synonym: Imidazole Carboxamide,DTIC-Dome
Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis
O6-Benzylguanine
T7539
Synonym:
Target: Apoptosis, DNA Alkylation, DNA/RNA Synthesis
Almonertinib
T5462
Synonym: HS-10296
Target: EGFR
Estramustine
T20681
Synonym: NSC-89201,NSC 89201,LEO 275,LEO275,NSC89201,LEO-275
Target: Microtubule Associated
Almonertinib hydrochloride
T5675
Synonym: HS-10296 hydrochloride
Target: EGFR
Bexarotene
T6410
Synonym: Ro 26-4455,Targretin,LGD1069
Target: Retinoid Receptor, Autophagy
Mitotane
T1199
Synonym: Mitotan,o,p'-DDD,NCI-C04933,2,4′-DDD
Target: Apoptosis, AChR
Methotrexate
T1485
Synonym: NCI-C04671,WR19039,Amethopterin,CL14377
Target: Apoptosis, Dehydrogenase, DNA/RNA Synthesis, Antifolate
Altretamine
T1241
Synonym: Hexamethylmelamine,NSC13875,RB-1515,ENT-50852,WR-95704
Target: DNA Alkylator/Crosslinker, DNA Alkylation
Vepafestinib
T9445
Synonym:
Target: c-RET
Cedazuridine
T26972
Synonym: (4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine
Target: DNA Methyltransferase
IDO inhibitor 1
T7660
Synonym:
Target: Indoleamine 2,3-Dioxygenase (IDO)
Vidarabine phosphate
T20048
Synonym:
Target: Antiviral
Tilorone dihydrochloride
T0244
Synonym:
Target: Influenza Virus, HIF/HIF Prolyl-Hydroxylase, IFNAR
Trofosfamide
T17172
Synonym:
Target: Antibacterial
Thio-TEPA
T1250
Synonym: Tiofosyl,Triethylenethiophosphoramide,Tiofosfamid
Target: DNA Alkylator/Crosslinker, DNA Alkylation, Antibacterial, Antibiotic
Antitumor agent-21
T3389
Synonym: TRX818
Target: Others
Icotinib
T6153
Synonym: BPI-2009,BPI-2009H,Conmana
Target: EGFR
Perifosine
T2492
Synonym: NSC 639966,D21266,KRX-0401
Target: Apoptosis, Akt, Autophagy
Galunisertib
T2510
Synonym: LY2157299
Target: TGF-beta/Smad
Vistusertib
T1961
Synonym: AZD2014
Target: Apoptosis, Akt, PI3K, S6 Kinase, mTOR, Autophagy
Serdemetan
T2243
Synonym: JNJ-26854165
Target: Apoptosis, Mdm2, E1/E2/E3 Enzyme, p53
Taladegib
T2666
Synonym: LY2940680
Target: Hedgehog/Smoothened, Smo
AST5902 mesylate(2412155-74-7 free base)
T8945L
Synonym:
Target: Drug Metabolite
Mobocertinib
T8151
Synonym: tak788
Target: EGFR
Tepotinib
T6121
Synonym: EMD-1214063,MSC2156119
Target: Trk receptor, c-Met/HGFR, TAM Receptor
Carmustine
T3091
Synonym: bis-chloroethylnitrosourea,Nitrumon,Gliadel,BCNU,BiCNU,Carmubris
Target: DNA Alkylator/Crosslinker, DNA Alkylation
Borofalan(10B)
T26889
Synonym: L-4-Boronophenylalanine
Target: Others
GSK2879552
T3677
Synonym: GSK2879552 2HCl
Target: Histone Demethylase
Pimasertib
T6131
Synonym: AS703026,MSC1936369B,SAR 245509
Target: MEK
Encorafenib
T6487
Synonym: LGX818
Target: Raf
Pixantrone dimaleate
T2394
Synonym: BBR-2778,Pixantrone Maleate,BBR 2778 dimaleate
Target: Topoisomerase
Hydroxyurea
T0676
Synonym: Hydroxycarbamide,nsc32065,nci-c04831
Target: Apoptosis, HIV Protease, DNA/RNA Synthesis, Autophagy
Apalutamide
T2339
Synonym: ARN-509
Target: Androgen Receptor, GABA Receptor
OTSSP167
T1759
Synonym: MELK inhibitor,OTS167
Target: MELK
Alobresib
T8495
Synonym: Vorolanib,GS-5829
Target: Epigenetic Reader Domain
1 2 3 4 5 6 7 8 9 10 11
Cat No. Product Name Synonyms Targets
T5778 5,7-DIMETHOXYFLAVONE Anti-infection , P450
5,7-DIMETHOXYFLAVONE possessed remarkable leishmanicidal potential.
T6431 Levoleucovorin Calcium Calcium Levofolinate,CL307782 Others , Antifolate
Levoleucovorin Calcium (CL307782), a calcium salt of the folinic acid, is used in cancer chemotherapy as an adjuvant.
TN1375 α-Lapachone alpha-Lapachone Topoisomerase , Antifection
α-Lapachone has antineoplastic activity, it shows an approximately trypanocidal activity against Trypanosoma cruzi.
T1174 Topotecan hydrochloride SKF 104864A,SKFS 104864A,NSC609699,Nogitecan HCl,NSC 609669,Topotecan HCl Apoptosis , Topoisomerase , Autophagy
Topotecan hydrochloride (NSC609699) is an antineoplastic agent used to treat ovarian cancer.
T2807 Caffeic Acid Lipoxygenase , Endogenous Metabolite , TRP/TRPV Channel
Caffeic Acid is an orally bioavailable, hydroxycinnamic acid derivative and polyphenol, with potential anti-oxidant, anti-inflammatory, and antineoplastic activities.
TN2101 Primin Antifection
Primin has antimycobacterial, and strong antineoplastic actions.
T4614 Ellipticine hydrochloride Ellipticine HCl,NSC 71795 (hydrochloride) Topoisomerase
Ellipticine hydrochloride (NSC-71795 (hydrochloride)) is a potent antineoplastic agent; inhibits DNA topoisomerase II activities.
T3801 (Rac)-Byakangelicin Bjacangelicin,Bjakangelicin,Biacangelicin,7H-Furo[3,2-g][1]benzopyran-7-one, 9-(2,3-dihydroxy-3-methylbutoxy)-4-methoxy-,Byakangelicin Others
(Rac)-Byakangelicin (7H-Furo[3,2-g][1]benzopyran-7-one, 9-(2,3-dihydroxy-3-methylbutoxy)-4-methoxy-) is an antineoplastic agent.
T3S1707 Dendrophenol Moscatilin NF-κB
Dendrophenol (Moscatilin) is a natural product isolated from the stem of Dendrobium loddigesii Rolfe, act as a NF-κB inhibitor. Antineoplastic activity.
TN1372 Alpha-Amyrin alpha-Amyrenol,α-Amyrin,alpha-Amyrine,Viminalol P450 , Serine Protease , ROS
Alpha-Amyrin (alpha-Amyrine) is an inhibitor of trypsin and chymotrypsin with antineoplastic effects. alpha-Amyrin can be used in studies about acting as a hepatomodulatory.
T0051 Urethane Ethyl carbamate,Ethylurethane,Carbamic acid ethyl ester Chloride channel , GABA Receptor , Antibacterial , GluR , NMDAR , AChR , Parasite
Urethane (Ethylurethane) was an antineoplastic agent .Now is used for other medicinal purposes.
T5784 Topotecan NSC 609669,SKF 104864A Topoisomerase , Autophagy
Topotecan (NSC-609669) is a Topoisomerase I inhibitor,and is an antineoplastic agent used to treat ovarian cancer that works by inhibiting DNA topoisomerases.
T1059 Retinyl palmitate Retinol palmitate,Vitamin A palmitate,Retinyl (Vitamin A) Palmitate Others , Endogenous Metabolite
Retinyl palmitate (Vitamin A palmitate) is a naturally-occurring phenyl analogue of retinol, with potential antineoplastic and chemopreventive activities.
T2898 Andrographolide Andrographis SARS-CoV , Influenza Virus , NF-κB , Autophagy
Andrographolide (Andrographis)(Andrographis), an irreversible antagonist of NF-κB, has anti-inflammatory and anti-platelet aggregation activities and potential antineoplastic.
T5A2455 Arenobufagin Others
Arenobufagin is a natural bufadienolide from toad venom with potent antineoplastic activity against HCC HepG2 cells and corresponding multidrug-resistant HepG2/ADM cells.
T1511 Daunorubicin hydrochloride Daunomycin HCl,RP-13057 Hydrochloride,Rubidomycin hydrochloride,Daunorubicin HCl,Daunomycin Apoptosis , DNA/RNA Synthesis , Topoisomerase , Antibacterial , Antibiotic , Autophagy
Daunorubicin hydrochloride (Rubidomycin hydrochloride), an anthracycline aminoglycoside antineoplastic, inhibits DNA replication and repair and RNA and protein synthesis.
T4803 (E/Z)-Demethoxycurcumin Others
Demethoxycurcumin is found in Curcuma zedoaria and Etlingera elatior. It has a role as a metabolite, an antineoplastic agent and an anti-inflammatory agent.
T2218 8-Azaguanine Azaguanine-8,SK 1150,NSC-749,SF-337 Nucleoside Antimetabolite/Analog , Others , Endogenous Metabolite
8-Azaguanine (SK 1150) is a purine analogue with potential antineoplastic activity.
T2993 Cordycepin 3'-Deoxyadenosine MMP , TNF , Antibacterial , Antibiotic , Autophagy
Cordycepin (3'-Deoxyadenosine) is a purine nucleoside antimetabolite and antibiotic isolated from the fungus Cordyceps militaris with potential antineoplastic activity.
T2543 Cabazitaxel XRP6258,RPR-116258A,TXD 258,taxoid XRP6258 Microtubule Associated , Autophagy
Cabazitaxel (taxoid XRP6258) is a taxane and antineoplastic agent which is currently used in the therapy of castration-resistant metastatic prostate cancer after failure of docetaxel.
T8373 6-Diazo-5-oxo-L-nor-Leucine DON,L-6-Diazo-5-oxonorleucine,Diazooxonorleucine Influenza Virus , Glutaminase , Antibacterial , Antibiotic
6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine) is an antagonist of glutaminases (Ki : 6 μM). It is an antineoplastic antibiotic produced by an unidentified species of Streptomyces from Peruvian soil.
T1737 Genistein NPI 031L Apoptosis , EGFR , Endogenous Metabolite , Autophagy
Genistein (NPI 031L) is an isoflavonoid derived from soy products. It inhibits protein-tyrosine kinase and topoisomerase-II (DNA TOPOISOMERASES, TYPE II), with antineoplastic and antitumor activities.
T2336 Vitamin K2 Menatetrenone Endogenous Metabolite
Vitamin K2 (Menatetrenone) is a menaquinone compound and form of vitamin K2 with potential antineoplastic activity. Menatetrenone may act by modulating the signaling of certain tyrosine kinases, thereby affecting several...
T6S0923 Hypericin Hypericine,Cyclosan Apoptosis , Antiviral , Influenza Virus , Tyrosine Kinases , Antibacterial , PKC
1. Hypericin (Cyclosan) has antineoplastic activity. 2. Hypericin has antibiotic and antiviral activities. 3. Hypericin has antidepressive activity through inhibiting monoamine oxidase enzyme. 4. Hypericin inhibits RANKL...
T0983 Penicillamine d-penicillamin,Dimethyl Cysteine,Artamine,D-(-)-Penicillamine Antibiotic
Penicillamine (Artamine), possessing antineoplastic properties, induces apoptosis by a p53-mediated mechanism and inhibits angiogenesis by chelating with copper, a cofactor for angiogenesis. Artamine is a beta dimethyl a...
T0650 Phenyl acetate Acetylphenol,Phenol acetate,Acetic acid phenyl ester Others , Endogenous Metabolite
Phenyl acetate (Acetic acid phenyl ester) is an aromatic fatty acid metabolite of phenylalanine with potential antineoplastic activity. Naturally occurring in mammals, phenylacetate induces differentiation, growth inhibi...
TN1087 Deoxypodophyllotoxin Apoptosis , Microtubule Associated , Autophagy
Deoxypodophyllotoxin shows cytotoxic , antineoplastic, antitumor, insecticidal, anti-angiogenic, vascular disrupting, insecticidal, antiviral, and anti-inflammatory activities.
T1705 5-Amino-3H-imidazole-4-Carboxamide 4-Amino-5-imidazolecarboxamide,AICA,5-Aminoimidazole-4-carboxamide Endogenous Metabolite
5-Amino-3H-imidazole-4-Carboxamide (AICA) is an imidazole derivative which is a metabolite of the antineoplastic agents BIC and DIC. By itself, or as the ribonucleotide, it is used as a condensation agent in the preparat...
T3314 Perillyl alcohol Isocarveol,Perilla alcohol Apoptosis , Endogenous Metabolite
Perillyl Alcohol is a naturally occurring monoterpene related to limonene with antineoplastic activity. Perillyl alcohol (Isocarveol) inhibits farnesyl transferase and geranylgeranyl transferase, thereby preventing post-...
T6569 Mimosine Leucenine,NSC 69188,Leucenol,L-Mimosine Others
L-Mimosine (Leucenol) is an antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca and acts as an iron chelator.
T1633 β-Carotene Carotaben,Beta-Carotene,Provitamin A Apoptosis , ROS , Endogenous Metabolite
β-Carotene (Provitamin A) is a naturally-occurring retinol (vitamin A) precursor obtained from certain fruits and vegetables with potential antineoplastic and chemopreventive activities. As an anti-oxidant, beta carotene...
T1506 Vidarabine Adenine Arabinoside,9-β-D-Arabinofuranosyladenine,Vira-A,Arabinosyladenine,Ara-A Nucleoside Antimetabolite/Analog , Tyrosine Kinases , DNA/RNA Synthesis , Antibiotic , HSV
Vidarabine (Adenine Arabinoside) is a nucleoside antibiotic isolated from Streptomyces antibioticus. It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and signific...
T1166 Ellipticine NSC 71795,Elliptisine Topoisomerase
Ellipticine (Elliptisine) is a potent antineoplastic agent exhibiting multiple mechanisms of action, IC50 of 0.67±0.06, 1.25±0.13, 1.25±0.13, 0.67±0.06, 0.27±0.02, 0.49±0.04, 0.44±0.03, and 1.48±0.62 μM for Leukemia HL-6...
TN1215 (2S)-2'-Methoxykurarinone 2'-Methoxykurarinone,2'-O-Methylkurarinone Akt , Antifection
(2S)-2'-Methoxykurarinone is isolated from the roots of Sophora flavescens. (2S)-2'-Methoxykurarinone has anti-inflammatory, antipyretic, antidiabetic, and antineoplastic effects. (2S)-2'-Methoxykurarinone inhibits osteo...
T1121 Podofilox Podophyllotoxin,(+)-Shikonin Microtubule Associated , Topoisomerase
Podofilox ((+)-Shikonin) is a lignan (LIGNANS) found in PODOPHYLLIN resin from the roots of PODOPHYLLUM plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irrit...
T5S0661 Koumine Others
1. Koumine can treat the diabetic neuropathy. 2. Koumine has antineoplastic effect, may be a future breast cancer chemotherapeutic agent. 3. Koumine has a significant analgesic effect in rodent behavioral models of infla...
T1719 Bufalin ATPase
Bufalin is an active ingredient and one of the glycosides in the traditional Chinese medicine ChanSu; it is also a bufadienolide toxin originally isolated from the venom of the Chinese toad Bufo gargarizans, with potenti...
T0186 Docetaxel trihydrate RP-56976 (Trihydrate),RP56976 (NSC 628503) Trihydrate Apoptosis , BCL , Microtubule Associated
Docetaxel trihydrate (RP-56976 Trihydrate) is an antineoplastic agent that has a unique mechanism of action as an inhibitor of cellular mitosis and that currently plays a central role in the therapy of many solid tumor i...
T3524 Halofuginone hydrobromide Tempostatin,RU-19110 (hydrobromide),Stenorol Others , Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad
Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor ce...
T5S1467 Cucurbitacin E CDK , Autophagy
Cucurbitacin E is a natural product isolated from the climbing stem of Cucumic melo L. It significantly suppresses the activity of the cyclin B1/CDC2 complex.Cucurbitacin E has prevention of neurodegeneration, it has pot...
T1611 Isotretinoin 13-cis-Retinoic acid Retinoid Receptor , Endogenous Metabolite , Autophagy
Isotretinoin (13-cis-Retinoic acid) binds to and activates nuclear retinoic acid receptors (RARs); activated RARs serve as transcription factors that promote cell differentiation and apoptosis. Isotretinoin is a naturall...
T2220 2-Methoxyestradiol NSC-659853,2-MeOE2,2-ME2 Apoptosis , Reactive Oxygen Species , Microtubule Associated , Endogenous Metabolite , HIF , Autophagy
2-Methoxyestradiol (2-ME2) is an orally bioavailable estradiol metabolite with potential antineoplastic activity. 2-Methoxyestradiol inhibits angiogenesis by reducing endothelial cell proliferation and inducing endotheli...
T3923 Calycosin Cyclosin,3'-Hydroxyformononetin Apoptosis , Tyrosinase
Calycosin (Cyclosin) acts as a selective estrogen receptor modulator. Calycosin induces apoptosis in human ovarian cancer SKOV3 cells by activating caspases and Bcl-2 family proteins. Calycosin suppresses breast cancer c...
T1591 Ancitabine hydrochloride NSC 145668 HCl,Cyclocytidine hydrochloride,Cyclo-CMP hydrochloride,Cyclocytidine HCl,Cyclo-C Others , DNA/RNA Synthesis , Autophagy
Ancitabine hydrochloride (NSC 145668 HCl) is the hydrochloride salt of a cytarabine congener prodrug with antineoplastic activity. Upon administration, ancitabine is slowly hydrolyzed into cytarabine. Subsequently, cytar...
T6429 Caffeic Acid Phenethyl Ester Phenylethyl Caffeate,CAPE Apoptosis , NF-κB
Caffeic Acid Phenethyl Ester (Phenylethyl Caffeate) (CAPE) inhibits the activation of nuclear transcription factor NF-kappa B and may suppress p70S6K and Akt-driven signaling pathways, with antineoplastic, cytoprotective...
T4919 Ureidopropionic acid Carbamoyl-b-alanine,3-Ureidopropionic acid Endogenous Metabolite
Ureidopropionic acid (3-Ureidopropionic acid) is an intermediate in the metabolism of uracil. More specifically it is a breakdown product of dihydrouracil and is produced by the enzyme dihydropyrimidase. It is further de...
T4S0797 Berberine Berberin,Umbellatine Reactive Oxygen Species , Topoisomerase , Endogenous Metabolite , Antibacterial , Antibiotic , Autophagy
1. Berberine (Umbellatine) is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism. 2. Berberine may as a broad-spectrum anti-microbial medicine, a complementary therapeutic agent for HIV/AIDS. 3....
T3S0027 Picropodophyllotoxin AXL 1717,Picropodophyllin IGF-1R
Picropodophyllotoxin (AXL 1717) is a cyclolignan alkaloid found in the mayapple plant family (Podophyllum peltatum), and a small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF1R) with potential anti...
T26030 Rabdosin C Isodonoiol,Rabdophyllin G
Rabdosin C is an antineoplastic isolated from the leaves of Rabdosia japonic.
T2S2378 7-Xylosyltaxol Others
7-xylosyltaxol is a taxol (Paclitaxel) derivative, has antineoplastic activity.
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Natural Products

5,7-DIMETHOXYFLAVONE
T5778
Synonym:
Target: Anti-infection, P450
Levoleucovorin Calcium
T6431
Synonym: Calcium Levofolinate,CL307782
Target: Others, Antifolate
α-Lapachone
TN1375
Synonym: alpha-Lapachone
Target: Topoisomerase, Antifection
Topotecan hydrochloride
T1174
Synonym: SKF 104864A,SKFS 104864A,NSC609699,Nogitecan HCl,NSC 609669,Topotecan HCl
Target: Apoptosis, Topoisomerase, Autophagy
Caffeic Acid
T2807
Synonym:
Target: Lipoxygenase, Endogenous Metabolite, TRP/TRPV Channel
Primin
TN2101
Synonym:
Target: Antifection
Ellipticine hydrochloride
T4614
Synonym: Ellipticine HCl,NSC 71795 (hydrochloride)
Target: Topoisomerase
(Rac)-Byakangelicin
T3801
Synonym: Bjacangelicin,Bjakangelicin,Biacangelicin,7H-Furo[3,2-g][1]benzopyran-7-one, 9-(2,3-dihydroxy-3-methylbutoxy)-4-methoxy-,Byakangelicin
Target: Others
Dendrophenol
T3S1707
Synonym: Moscatilin
Target: NF-κB
Alpha-Amyrin
TN1372
Synonym: alpha-Amyrenol,α-Amyrin,alpha-Amyrine,Viminalol
Target: P450, Serine Protease, ROS
Urethane
T0051
Synonym: Ethyl carbamate,Ethylurethane,Carbamic acid ethyl ester
Target: Chloride channel, GABA Receptor, Antibacterial, GluR, NMDAR, AChR, Parasite
Topotecan
T5784
Synonym: NSC 609669,SKF 104864A
Target: Topoisomerase, Autophagy
Retinyl palmitate
T1059
Synonym: Retinol palmitate,Vitamin A palmitate,Retinyl (Vitamin A) Palmitate
Target: Others, Endogenous Metabolite
Andrographolide
T2898
Synonym: Andrographis
Target: SARS-CoV, Influenza Virus, NF-κB, Autophagy
Arenobufagin
T5A2455
Synonym:
Target: Others
Daunorubicin hydrochloride
T1511
Synonym: Daunomycin HCl,RP-13057 Hydrochloride,Rubidomycin hydrochloride,Daunorubicin HCl,Daunomycin
Target: Apoptosis, DNA/RNA Synthesis, Topoisomerase, Antibacterial, Antibiotic, Autophagy
(E/Z)-Demethoxycurcumin
T4803
Synonym:
Target: Others
8-Azaguanine
T2218
Synonym: Azaguanine-8,SK 1150,NSC-749,SF-337
Target: Nucleoside Antimetabolite/Analog, Others, Endogenous Metabolite
Cordycepin
T2993
Synonym: 3'-Deoxyadenosine
Target: MMP, TNF, Antibacterial, Antibiotic, Autophagy
Cabazitaxel
T2543
Synonym: XRP6258,RPR-116258A,TXD 258,taxoid XRP6258
Target: Microtubule Associated, Autophagy
6-Diazo-5-oxo-L-nor-Leucine
T8373
Synonym: DON,L-6-Diazo-5-oxonorleucine,Diazooxonorleucine
Target: Influenza Virus, Glutaminase, Antibacterial, Antibiotic
Genistein
T1737
Synonym: NPI 031L
Target: Apoptosis, EGFR, Endogenous Metabolite, Autophagy
Vitamin K2
T2336
Synonym: Menatetrenone
Target: Endogenous Metabolite
Hypericin
T6S0923
Synonym: Hypericine,Cyclosan
Target: Apoptosis, Antiviral, Influenza Virus, Tyrosine Kinases, Antibacterial, PKC
Penicillamine
T0983
Synonym: d-penicillamin,Dimethyl Cysteine,Artamine,D-(-)-Penicillamine
Target: Antibiotic
Phenyl acetate
T0650
Synonym: Acetylphenol,Phenol acetate,Acetic acid phenyl ester
Target: Others, Endogenous Metabolite
Deoxypodophyllotoxin
TN1087
Synonym:
Target: Apoptosis, Microtubule Associated, Autophagy
5-Amino-3H-imidazole-4-Carboxamide
T1705
Synonym: 4-Amino-5-imidazolecarboxamide,AICA,5-Aminoimidazole-4-carboxamide
Target: Endogenous Metabolite
Perillyl alcohol
T3314
Synonym: Isocarveol,Perilla alcohol
Target: Apoptosis, Endogenous Metabolite
Mimosine
T6569
Synonym: Leucenine,NSC 69188,Leucenol,L-Mimosine
Target: Others
β-Carotene
T1633
Synonym: Carotaben,Beta-Carotene,Provitamin A
Target: Apoptosis, ROS, Endogenous Metabolite
Vidarabine
T1506
Synonym: Adenine Arabinoside,9-β-D-Arabinofuranosyladenine,Vira-A,Arabinosyladenine,Ara-A
Target: Nucleoside Antimetabolite/Analog, Tyrosine Kinases, DNA/RNA Synthesis, Antibiotic, HSV
Ellipticine
T1166
Synonym: NSC 71795,Elliptisine
Target: Topoisomerase
(2S)-2'-Methoxykurarinone
TN1215
Synonym: 2'-Methoxykurarinone,2'-O-Methylkurarinone
Target: Akt, Antifection
Podofilox
T1121
Synonym: Podophyllotoxin,(+)-Shikonin
Target: Microtubule Associated, Topoisomerase
Koumine
T5S0661
Synonym:
Target: Others
Bufalin
T1719
Synonym:
Target: ATPase
Docetaxel trihydrate
T0186
Synonym: RP-56976 (Trihydrate),RP56976 (NSC 628503) Trihydrate
Target: Apoptosis, BCL, Microtubule Associated
Halofuginone hydrobromide
T3524
Synonym: Tempostatin,RU-19110 (hydrobromide),Stenorol
Target: Others, Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad
Cucurbitacin E
T5S1467
Synonym:
Target: CDK, Autophagy
Isotretinoin
T1611
Synonym: 13-cis-Retinoic acid
Target: Retinoid Receptor, Endogenous Metabolite, Autophagy
2-Methoxyestradiol
T2220
Synonym: NSC-659853,2-MeOE2,2-ME2
Target: Apoptosis, Reactive Oxygen Species, Microtubule Associated, Endogenous Metabolite, HIF, Autophagy
Calycosin
T3923
Synonym: Cyclosin,3'-Hydroxyformononetin
Target: Apoptosis, Tyrosinase
Ancitabine hydrochloride
T1591
Synonym: NSC 145668 HCl,Cyclocytidine hydrochloride,Cyclo-CMP hydrochloride,Cyclocytidine HCl,Cyclo-C
Target: Others, DNA/RNA Synthesis, Autophagy
Caffeic Acid Phenethyl Ester
T6429
Synonym: Phenylethyl Caffeate,CAPE
Target: Apoptosis, NF-κB
Ureidopropionic acid
T4919
Synonym: Carbamoyl-b-alanine,3-Ureidopropionic acid
Target: Endogenous Metabolite
Berberine
T4S0797
Synonym: Berberin,Umbellatine
Target: Reactive Oxygen Species, Topoisomerase, Endogenous Metabolite, Antibacterial, Antibiotic, Autophagy
Picropodophyllotoxin
T3S0027
Synonym: AXL 1717,Picropodophyllin
Target: IGF-1R
Rabdosin C
T26030
Synonym: Isodonoiol,Rabdophyllin G
Target:
7-Xylosyltaxol
T2S2378
Synonym:
Target: Others
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Recombinant Proteins

Species：
Human (1)
Expression System：
Baculovirus-Insect Cells (1)
Tag：
Tag Free (1)
Cat No. Product Name Species Expression System
TMPY-03431 HDAC4 Protein, Human, Recombinant (aa 612-1084) Human Baculovirus-Insect Cells
HDAC4 (histone deacetylase 4), belongs to class II of the histone deacetylase/AcuC/APhA family. Histone Deacetylases (HDACs) are a group of enzymes closely related to sirtuins. They catalyze the removal of acetyl groups ...
Cat No. Product Name
L6100 Polyphenolic Natural Product Library

640 compounds
A unique collection of 640 natural polyphenolic compounds for high throughput screening (HTS) and high content screening (HCS);

Libraries

Polyphenolic Natural Product Library
L6100
Compounds: 640
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