281
123
178
5
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T37071 | Pyrimethanil | Antifungal | |
Pyrimethanil is a strobilurin fungicide belonging to the anilinopyrimidine class. Pyrimethanil is a broad-spectrum contact fungicide for the control of Botrytis spp. on a wide variety of crops. Pyrimethanil inhibits the ... | |||
T14362 | AY 9944 | Others | |
AY 9944 is a specific cholesterol biosynthesis inhibitor. AY 9944 inhibits the 7-dehydro cholesterol Δ7-reductase (DHCR7) enzyme (IC50=13 nM). At high doses, AY 9944 inhibits also in cultured embryos sterol Δ7-Δ8 isomera... | |||
T19859 | Nicosulfuron | Milagro,Accent,Motivell | Others |
Nicosulfuron (Milagro) is a pesticide that works by inhibiting the acetolactate synthase enzyme. Nicosulfuron has not been found to induce mutagenic or carcinogenic effects. Nicosulfuron is a herbicide to protect corn cr... | |||
T20237 | Fenhexamid | Elevate,Teldor | Antifungal |
Fenhexamid (Elevate), a sterol biosynthesis inhibitor, shows antifungal activity against the plant pathogenic fungus. Fenhexamid is used for agriculture and is present in measurable amounts in fruits and vegetables. | |||
T33828 | O-Succinylhomoserine | O-Succinyl-L-homoserine | Others |
O-Succinylhomoserine (O-Succinyl-L-homoserine) is an intermediate in the synthesis of cystathionine by E coli.. | |||
T20691 | Fenpropidin | Ro12-3049,Ro-12-3049,Ro 12-3049 | Antifungal |
Fenpropidin (Ro-12-3049), a fungicide, is a specific inhibitor of sterol 14-reductase and biosynthesis. | |||
T15507 | Hycanthone | Etrenol(mesylate),Win 249-33 | DNA/RNA Synthesis , Topoisomerase , Parasite |
Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal. Hycanthone is a DNA intercalator that inhibits RNA synthesis and DNA topoisomerases I and II. Hycanthone inhibits nucleic acid biosynthesis and inhibit... | |||
T20625 | Prochloraz | Sporgon,Prelude | Estrogen Receptor/ERR , AhR , Androgen Receptor , Antifungal |
Prochloraz (Prelude) is a broad-spectrum contact imidazole fungicide. Prochloraz inhibits human placental microsomal aromatase in vitro (IC50 = 40 nM). Prochloraz also acts as an estrogen receptor (IC50s = 25 μM) and and... | |||
T26296 | Triparanol | MER-29,NSC 65345,NSC-65345,NSC65345 | Apoptosis , Hedgehog/Smoothened |
Triparanol (NSC-65345) interferes with posttranslational modification of Hedgehog signaling molecules as well as the sterol sensing domain of its receptor PTCH1, leading to down-regulation of Hedgehog signaling. Triparan... | |||
T6893 | MK-886 | MK886,L 663536 | Apoptosis , Leukotriene Receptor , COX , PPAR , FLAP |
MK-886 (L 663536) is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP). It is also a moderately potent PPARα antagonist. | |||
T2305 | Isavuconazole | BAL-4815,RO-0094815 | P450 , Antibiotic , Antifungal |
Isavuconazole (RO-0094815)(BAL-4815; RO-0094815) is the active component of the new azole antifungal agent BAL8557 with MIC(50)s/MIC(90)s ranged from 0.002/0.004 mg/liter for C. albicans to 0.25/0.5 mg/liter for C. glabr... | |||
T19721 | Epoxiconazole | BAS-480F,BAS 480F,EC 406 850 2,BAS480F,EC-406-850-2 | Antifungal |
Epoxiconazole (BAS-480F) is a 14-α demethylase inhibitor. It inhibits ergosterol synthesis and fungal cell wall formation. | |||
T24327 | L 674573 | L 674,573,L674,573,L-674,573,L674573,L-674573 | Leukotriene Receptor |
L 674573 is an inhibitor of leukotriene biosynthesis. | |||
T72045 | Fmoc-N-methyl-L-alloisoleucine | ||
Fmoc-N-methyl-L-alloisoleucine is a biochemical reagent for biosynthesis. | |||
T13312L | Seviteronel | VT-464 | Others |
Seviteronel is an effective CYP17 lyase inhibitor (h-Lyase IC50=69 nM). In a hamster model of androgen biosynthesis inhibition, it demonstrated both exceptional in vitro lyase/hydroxylase selectivity (~10-fold) and oral... | |||
T27112 | Cytembena | DNA/RNA Synthesis | |
Cytembena is a cytostatic and a carcinogenic compound that may increase the incidence of fibroadenomas.Cytembena broadly inhibits DNA biosynthesis. | |||
T77625 | CCG-13514 | Others | |
CCG-13514 is a biochemical reagent to be developed for biosynthesis. | |||
T11933 | MAC13772 | Others | |
MAC13772 is a potent inhibitor of the enzyme BioA with an IC50 of 250 nM thereby inhibiting biotin biosynthesis. MAC13772 exhibits antibacterial activity. | |||
T12092 | Monacolin J | Antibiotic MB 530A,Lovastatin diol lactone | HMG-CoA Reductase , Autophagy |
Monacolin J (Antibiotic MB 530A) is a cholesterol biosynthesis inhibitor. | |||
T9994 | WAY-620521 | Others | |
WAY-620521 is a cell-based high-throughput assay to identify small molecules that inhibit phospholipid biosynthesis in animal cells. | |||
T0506 | Clotrimazole | BAY b 5097,FB 5097 | Antibacterial , Antibiotic , Antifection , Autophagy , Antifungal |
Clotrimazole (FB 5097), an imidazole derivative with a broad spectrum of antimycotic activity, inhibits biosynthesis of the sterol ergostol. | |||
T32237 | Isoxaben | EL 107,NA 8318,Isoxaben; EL 107; NA 8318 | Cell wall |
Isoxaben (EL 107) is a specific inhibitor of cell wall biosynthesis, often used as a herbicide, that inhibits the incorporation of radiolabeled glucose into acid-insoluble cell wall fractions. | |||
T33584 | Namirotene | CBS 211A,Cbs 211 A | Others |
Namirotene (CBS 211A) is a protein biosynthesis inhibitor, a synthetic retinoic acid analog that is used in the study of corneal diseases, corneal ulcers and dry eye syndrome. | |||
TQ0115 | NB-598 | Antifungal | |
NB-598 is an effective and competitive inhibitor of squalene epoxidase. It suppresses triglyceride biosynthesis through the farnesol pathway. | |||
T31163 | Cytidine 5'-diphosphate disodium | CDP sodium salt,Cytidine 5'-diphosphate disodium salt,Cytidine diphosphate sodium salt | Others |
Cytidine 5'-diphosphate disodium (CDP sodium salt) produces CTP to support DNA and RNA biosynthesis and ribonucleotide reductase to produce dCMP. | |||
T9369L | UDP-a-D-Galactose disodium salt | Others | |
UDP-a-D-Galactose disodium salt is a donor substrate for galactosyltransferases employed in the biosynthesis of galactose-containing oligosaccharides[1]. | |||
T2199 | Myclobutanil | Systhane | Antifungal |
Myclobutanil (Systhane) is a triazole chemical used as a fungicide. It is a steroid demethylation inhibitor, specifically inhibiting ergosterol biosynthesis. Ergosterol is a critical component of fungal cell membranes. | |||
T32490 | L-161240 | L-161,240 | Antibacterial |
L-161240 is an antimicrobial agent associated with lipid A biosynthesis with an IC50 value of 30 nM as determined by DEACET and a MIC value of 1-3 μg/ mL against wild-type E. coli. | |||
T4982 | Benznidazol | Radanil,Benznidazole,Ro 71051,Ro 07-1051 | Antibiotic , Parasite |
Benznidazol (Benznidazole)e has an antiprotozoal activity by interfering with parasite protein biosynthesis, influencing cytokines production and stimulating host phagocytosis. | |||
T4055 | Etoxazole | Others | |
Etoxazole is an acaricide/insecticide that works via chitin biosynthesis inhibition for the control of mites. Used as a standard for Pesticide detection. | |||
T8332 | Bipenquinate | Dehydrogenase | |
Bipenquinate is a potent and selective inhibitor of dihydroorotate dehydrogenase (DHODH) with IC50 of 20 nM, blocking de novo pyrimidine biosynthesis. | |||
T5955 | Tricyclazole | Tricyclazol | Antibacterial |
Tricyclazole (Tricyclazol) is a pentaketide-derived melanin biosynthesis inhibitor. Tricyclazole is a a unique fungicide for control of Pyricularia oryzae on rice. | |||
T27094 | CT-2584 | CT2584 | |
CT-2584 is an angiogenesis inhibitor and lysophosphatidic acid acyltransferase inhibitor. CT-2584 inhibits phospholipid signaling. By inhibiting CTP:choline-phosphate cytidylyltransferase (CT), CT-2584 caused de novo pho... | |||
T1869 | PluriSIn 1 | NSC 14613,PluriSIn #1,PluriSln 1 | Apoptosis , Dehydrogenase , Stearoyl-CoA Desaturase (SCD) |
PluriSIn 1 (NSC 14613) is an inhibitor of stearoyl-CoA desaturase (SCD1), the key enzyme in oleic acid biosynthesis, revealing a unique role for lipid metabolism in hPSCs. | |||
T0002 | Ethamsylate | Cyclonamine,Etamsylate,Dicynene,Aglumin | Prostaglandin Receptor |
Ethamsylate (Dicynene) usually is used as a hemostatic drug, which increases capillary endothelial resistance and platelet adhesion, and inhibits biosynthesis and action of prostaglandins. | |||
T17176 | Salicyl-AMS | Antibacterial | |
Salicyl-AMS is an inhibitor of mycobacterium auxin biosynthesis that inhibits the growth of mycobacterium in the presence of iron deficiency in vitro. | |||
T1998 | CHS-828 | CHS 828,GMX1778 | Apoptosis , NAMPT |
CHS-828 (GMX1778), a pyridyl cyanoguanidine, is an effective inhibitor of NAD+ biosynthesis enzyme NAMPT (IC50 <25 nM). | |||
T19508 | Peroxidase | Others | |
Peroxidase, found in the roots of horseradish, actively involves in oxidizing reactive oxygen species, innate immunity, hormone biosynthesis, and pathogenesis of several diseases. | |||
T1356 | 4-Hydroxy-3-methoxybenzylamine hydrochloride | N-Vanillylamine hydrochloride | Others |
4-Hydroxy-3-methoxybenzylamine hydrochloride (N-Vanillylamine hydrochloride) is an alkaloid that is an intermediate in the biosynthesis of capsaicin. 4-Hydroxy-3-methoxybenzylamine hydrochloride is produced from vanillin... | |||
T65347 | Methyl acetyl-L-cysteinate | (R)-Methyl 2-acetamido-3-mercaptopropanoate,N-Acetyl-L-cysteine methyl ester | Amino Acids and Derivatives |
Methyl acetyl-L-cysteinate (N-Acetyl-L-cysteine methyl ester) is a cysteine derivative that is used in biosynthesis and is associated with body metabolism and immunity. | |||
T19781 | Clomazone | Gamit,FMC 57020,Command,Dimethazone,Magister | Others |
Clomazone (Magister) is an agricultural herbicide. The molecule consists of a 2-chlorobenzyl group bound to an N-O heterocycle called Isoxazole. Clomazone suppresses the biosynthesis of chlorophyll and other plant pigmen... | |||
T15608 | Jarin-1 | Others | |
Jarin-1 is a jasmonic acid-amido synthetase (JAR1) inhibitor (IC50: 3.8 μM). Jarin-1 specific suppresses bioactive JA biosynthesis in Arabidopsis and other plants. | |||
T0260 | Meclofenamic acid sodium | Meclofenamate Sodium,Movens,Meclomen,Meclonax | Gap Junction Protein , COX |
Meclofenamic acid sodium (Movens), a non-steroidal anti-inflammatory agent, has properties of antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis. | |||
T1447 | Fenclonine | Fenchlonine,PCPA,CP-10188,4-Chloro-DL-phenylalanine,DL-4-Chlorophenylalanine | Hydroxylase |
Fenclonine (CP-10188) is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine(CP-10188) acts pharmacologically to dep... | |||
T9085 | JFD01307SC | [(1,1-DIOXIDOTETRAHYDROTHIEN-3-YL)AMINO] | Antibacterial |
JFD01307SC ([(1,1-DIOXIDOTETRAHYDROTHIEN-3-YL)AMINO]) is a glutamine synthetase inhibitor. It is anti-tuberculosis agent and acts as a mimic of L-Glutamate and thus target enzymes involved in glutamine biosynthesis. | |||
T35973 | Cholesterol-5α,6α-epoxide | Epoxycholesterol,5α,6α-epoxy Cholestanol,NSC 18176 | Others |
Cholesterol-5α,6α-epoxide (Epoxycholesterol) is the metabolite of cholesterol produced by oxidation. Cholesterol-5α,6α-epoxide induces triacylglycerol biosynthesis by binding to LXRβ following tamoxifen and PBPE applicat... | |||
T3268 | Mildronate | Kvaterin,Meldonium,Quaterin | Hydroxylase |
Mildronate (Meldonium) is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine reabsorption. | |||
T21482 | Uniconazole | P450 , ROS Kinase | |
Uniconazole is a plant growth regulator that inhibit cytochrome P450 707As (Ki=68 nM). CYP707As is a major ABA catabolic enzyme that catabolize Abscisic acid, accordingly suppress gibberellin and sterol biosynthesis. | |||
T22352 | L-Gulose | Others , Endogenous Metabolite | |
L-Gulose is an unnatural monosaccharide. L-Gulose is the putative furanose form of L-sorbosone that exists as a syrup with a sweet taste. It is an L-hexose sugar and an intermediate in the biosynthesis of L-Ascorbate (vi... | |||
T2213 | Terconazole | Gyno-Terazol,Terazol 3,Terazol 7,Triaconazole,R42470 | Antifection , Antifungal |
Terconazole (Terazol 7) is a synthetic triazole derivative structurally related to fluconazole, antifungal Terconazole seems to disrupt cell wall synthesis by inhibiting biosynthesis of ergosterol or other sterols, damag... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3816 | Velutin | NF-κB , HIF/HIF Prolyl-Hydroxylase | |
Velutin shows the strongest inhibitory effect in NF-κB activation and exhibits the greatest effects in blocking the degradation of inhibitor of NF-κB as well as in inhibiting mitogen-activated protein kinase p38 and JNK ... | |||
T8115 | Menthofuran | Others | |
Menthofuran is a natural product. | |||
TN1576 | Diallyl disulfide | IL Receptor , NOS , NF-κB | |
Diallyl disulfide has antitumor effect, the effect can be enhanced by miR-200b and miR-22. | |||
TN6715 | 7-Ketocholesterol | Others | |
7-Ketocholesterol is a metabolite of Cholesterol | |||
T2919 | Sesamin | Fagarol,Fsesamin | Others |
Sesamin (Fsesamin) is a lignan extracted from Sesamum indicum L. | |||
TN2331 | Eleutheroside B1 | Influenza Virus | |
Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits l... | |||
T4834 | Indole-3-acetamide | 3-Indoleacetamide,3-Indolylacetamide | Others , Endogenous Metabolite |
1H-Indole-3-acetamide (3-Indolylacetamide), also known as auxin amide or 2-(3-indolyl)acetamide, belongs to the class of organic compounds known as 3-alkylindoles. Within the cell, 1H-indole-3-acetamide is primarily loca... | |||
T1589 | D-Cycloserine | RO-1-9213 | Others , Antibacterial , Antibiotic , iGluR |
D-Cycloserine (RO-1-9213) is a broad spectrum antibiotic used as a second line agent for treatment of drug resistant tuberculosis, always in combination with other antituberculosis agents. | |||
T7786 | Tryptanthrin | DNA gyrase | |
Tryptanthrin is a natural DNA gyrase inhibitor. | |||
T7132 | (Rac)-Brassinazole | BRASSINAZOLE | P450 |
(Rac)-Brassinazole are a class of phytohormones with essential roles in plant growth and development, including the promotion of stem elongation and cell division. Brassinazole is a triazole-type brassinosteroid biosynth... | |||
T4454 | Traumatic Acid | Dodec-2-Enedioic Acid,2E-Dodecenedioic Acid,Trans-2-Dodecenedioic Acid | Antioxidant |
Traumatic Acid (Dodec-2-Enedioic Acid) is a product of the hydroperoxide lyase pathway in plants. Potential as a wound healing agent that stimulates cell division near a wound site to form a protective callus. | |||
T9086 | Deoxythymidine-5'-triphosphate trisodium | dTTP trisodium salt,thymidine 5'-(trisodium hydrogen triphosphate),Deoxythymidine-5'-triphosphate (dTTP) trisodium salt | DNA/RNA Synthesis |
Deoxythymidine-5'-triphosphate trisodium (Deoxythymidine-5'-triphosphate (dTTP) trisodium salt) is one of the four natural deoxynucleotides. It is used for the biosynthesis of deoxyribonucleic acid by DNA polymerase and ... | |||
T5875 | 4-Methoxycinnamic acid | Endogenous Metabolite | |
4-Methoxycinnamic acid is an unusual phenylpropanoid involved in phenylphenalenone biosynthesis in Anigozanthos preissi. | |||
T8273 | 4,6-Dioxoheptanoic acid | Succinylacetone | Others , Endogenous Metabolite |
4,6-Dioxoheptanoic acid (Succinylacetone) acts as a potent inhibitor of heme biosynthesis. | |||
T5284 | N-Carbamoyl-DL-aspartic acid | N-Carbamoyl-DL-aspartic acid,Ureidosuccinic acid | Others , Endogenous Metabolite |
N-Carbamoyl-DL-aspartic acid (Ureidosuccinic acid) is an intermediary product in pyrimidine biosynthesis. | |||
T21130 | Precocene II | AI3-36847,Ageratochromene,BRN 0160683 | Others |
Precocene II (Ageratochromene), an antiallotropin compound, inhibits juvenile hormone biosynthesis. Precocene II has insecticidal, antifungal, antibacterial, and antioxidant activities. | |||
T19711 | Desmosterol | Desmesterol,24-Dehydrocholesterol | Endogenous Metabolite |
Desmosterol (24-Dehydrocholesterol) is a cholesterol biosynthesis intermediate that inhibits macrophage inflammatory vesicle activation and prevents vascular inflammation and atherosclerosis. | |||
T4795 | Pimelic acid | Pileric acid,1,7-Heptanedioic acid,1,5-Pentanedicarboxylic acid | Others , Endogenous Metabolite |
Derivatives of Pimelic acid (1,5-Pentanedicarboxylic acid) can participate in the biosynthesis of lysine. | |||
TQ0273 | Neopterin | D-(+)-Neopterin,2-Amino-6-((1S,2R)-1,2,3-trihydroxypropyl)pteridin-4(3H)-one | Endogenous Metabolite |
D-(+)-Neopterin (D-(+)-Neopterin) is produced by human monocytes/macrophages upon stimulation with the cytokine interferon-γ. In humans, neopterin is involved in purine biosynthesis. | |||
TN2237 | Steviol-19-O-glucoside | Steviol-19-O-Glucoside | Others |
Steviol-19-O-glucoside is a natural product from the steviol glycosides biosynthesis pathway in Stevia rebuadiana. | |||
T2748 | Cortodoxone | 11-Deoxycortisol,cortexolone,17α,21-dihydroxyprogesterone,Reichstein's substance S,11-Desoxycortisol | Glucocorticoid Receptor , Endogenous Metabolite |
Cortodoxone (11-Desoxycortisol) is a glucocorticoid steroid hormone that is an intermediate in the biosynthesis of cortisol in the adrenal gland. | |||
T8949 | UDP-g acid | Others | |
UDP-g acid is a sugar used in the production of polysaccharides and is an intermediate in the biosynthesis of ascorbic acid | |||
T4972 | 2'-Deoxycytidine-5'-diphosphate trisodium | dCDP | Endogenous Metabolite |
2'-Deoxycytidine-5'-diphosphate trisodium (dCDP) is used as a substrate of CDP (nucleoside diphosphate) kinase (2.7.4.6) for the production of dCTP to support DNA biosynthesis and reverse transcription. | |||
T1662 | 5-Aminolevulinic acid hydrochloride | Hydrangin,5-ALA,5-Aminolevulinic acid HCl,ALA hydrochloride | Apoptosis , Mitophagy , Endogenous Metabolite , Autophagy |
5-Aminolevulinic acid hydrochloride (5-ALA) serves as an intermediate in the body's heme biosynthesis and is the universal precursor of tetrapyrroles. | |||
T4923 | 7-Dehydrocholesterol | Provitamin D3,7-DHC | Endogenous Metabolite |
7-Dehydrocholesterol (Provitamin D3) down-regulates cholesterol biosynthesis in cultured Smith-Lemi-Opitz syndrome skin fibroblasts. | |||
T3003 | 5-hydroxytryptophan | NSC-92523 | Others , Endogenous Metabolite |
5-hydroxytryptophan (NSC-92523) is the immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant. | |||
T4921 | Oxoadipic acid | 2-Oxoadipic acid | Endogenous Metabolite |
Oxoadipic acid (2-Oxoadipic acid) is a key metabolite of the essential amino acids tryptophan and lysine.Important metabolite between the TCA cycle and lysine biosynthesis. Of interest for research on mitochondrial metab... | |||
T4721 | β-Nicotinamide mononucleotide | β-NM | Others , Endogenous Metabolite |
β-Nicotinamide mononucleotide (β-NM) is an important intermediate metabolite in the nicotinate and nicotinamide metabolism pathway. Mammals predominantly use nicotinamide rather than nicotinic acid as a precursor for NAD... | |||
T2739 | Shikimic Acid | Shikimate | Others , Endogenous Metabolite |
Shikimic Acid (Shikimate) is a tri-hydroxy cyclohexene carboxylic acid important in the biosynthesis of so many compounds that the shikimate pathway is named after it. | |||
T12796 | S-Dihydrodaidzein | (3S)-7-hydroxy-3-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one | Others |
S-Dihydrodaidzein ((3S)-7-hydroxy-3-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one) is an enantiomer of dihydrodaidzein which is involved in equol biosynthesis in a lactic acid bacterium, Lactococcus sp. strain. | |||
T79972 | Cyclo(L-leucyl-L-valyl) | ||
Cyclo(L-leucyl-L-valyl) suppresses Aflatoxin biosynthesis in Aspergillus parasiticus by inhibiting the transcription of Aflatoxin-associated genes, including aflR, hexB, pksL1, and dmtA.[1] | |||
T4722 | O-Acetyl-L-serine hydrochloride | Others , Endogenous Metabolite | |
O-Acetylserine (OASS) is an acylated amino acid derivative. It is an intermediate in the biosynthesis of the common amino acid cysteine in bacteria and plants. Its presence in humans arises from either microbial metaboli... | |||
T5225 | Hypotaurine | 2-Aminoethanesulfinic acid,2-Aminoethylsulfinic acid | Chloride channel , Endogenous Metabolite |
Hypotaurine (2-Aminoethanesulfinic acid), functioning as an intermediate in the biosynthesis of taurine from cysteine within astrocytes, acts as an endogenous inhibitory amino acid targeting the glycine receptor. | |||
T0146 | Tioconazole | UK-20349,Vagistat | Antibiotic , Antifection , Antifungal |
Tioconazole (Vagistat) is a synthetic imidazole derivative, inhibits cell wall synthesis by inhibiting the biosynthesis of ergosterol or other sterols, damaging the fungal cell membrane, altering its permeability, and pr... | |||
T21065 | Artemisitene | Others | |
Artemisitene is the oxidized form of Artemisinin and is an antimalarial agent. Artemisinin precursors are the important basic substances for biosynthesis of Artemisinin, including Artemisinin B, Artemisitene, Artemisini... | |||
T3324 | Lycorine | Galanthidine,Narcissine,Amarylline,Belamarine,Licorine | Apoptosis , Virus Protease , Antibacterial , AChR , Fatty Acid Synthase |
Lycorine (Narcissine) inhibits protein synthesis and may inhibit ascorbic acid biosynthesis, although studies on the latter are controversial and inconclusive. | |||
T5578 | L-Gulono-1,4-lactone | Others , Endogenous Metabolite | |
L-Gulono-1,4-lactone is a substrate of L-gulono-1,4-lactone oxidoreductase, which catalyzes the last step of the biosynthesis of L-ascorbic (Vitamin) C. | |||
T3948 | Undecanoic acid | Hendecanoic acid,Undecylic acid | Others , Endogenous Metabolite , Antifungal |
Undecanoic acid (Hendecanoic acid) is a monocarboxylic acid with antimycotic property. Undecanoic acid inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum. | |||
T2760 | (S)-2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid dihydrate | Iodogorgoic acid,apothyrin,jodgorgon,3,5-Diiodotyrosine Dihydrate | Others , Endogenous Metabolite |
(S)-2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid dihydrate (jodgorgon) is a product from the iodination of MONOIODOTYROSINE. In the biosynthesis of thyroid hormones, diiodotyrosine residues are coupled with other... | |||
T41054 | γ-Glutamyl-S-allylcysteine | L-γ-Glutamyl-(S)-Allyl-Cysteine | Antioxidant |
γ-Glutamyl-S-allylcysteine (L-γ-Glutamyl-(S)-Allyl-Cysteine) is a γ-glutamyl peptide extracted from Allium sativum L. γ-Glutamyl-S-allylcysteine possesses anti-glycation and antioxidant activities, and can inhibit the ch... | |||
T4731 | 2'-Deoxycytidine-5'-monophosphoric acid | dCMP,2'-Deoxycytidine 5'-monophosphate | Others , Endogenous Metabolite |
2'-Deoxycytidine-5'-monophosphoric acid (2'-Deoxycytidine 5'-monophosphate) is used as a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) to form dCDP which upon phosphorylation t... | |||
TN6993 | Benzylideneacetone | Benzalacetone | Phospholipase , Endogenous Metabolite |
Benzylideneacetone, a monoterpene produced by the insect pathogenic bacterium Xenorhabdus nematophila, is a phospholipase A2 (PLA2) inhibitor with inhibitory effects on arachidonoid biosynthesis and enhances baculovirus ... | |||
T7040 | Angiotensin II human | DRVYIHPF,Angiotensin II,Hypertensin II,Ang II | Apoptosis , RAAS |
Angiotensin II human (Ang II) is a biologically active peptide, a vasoconstrictor. Angiotensin II interacts with AT1R and AT2R to regulate blood pressure, stimulate sympathetic nerves, and increase aldosterone biosynthes... | |||
TN2296 | Vinaginsenoside R4 | Others | |
Vinaginsenoside R4 was isolated from the leaves of hydroponically grown ginseng. It inhibits melanin biosynthesis and enhances pigmentation in zebrafish without any cytotoxic effects on melan-a cells. It may have potenti... | |||
TN1051 | 1-Caffeoylquinic acid | NF-κB | |
1-Caffeoylquinic acid is an important intermediate in lignin biosynthesis. 1-Caffeoylquinic acid has anti-influenza, and antioxidant activities, it also slows the release of glucose into the bloodstream after a meal. | |||
T6702 | Terbinafine | Terbinex,SF 86-327,Lamisil,TDT 067 | Antibacterial , Antibiotic , Antifungal |
Terbinafine (TDT 067) is a synthetic allylamine derivative with antifungal activity. Terbinafine exerts its effect through inhibition of squalene epoxidase, thereby blocking the biosynthesis of ergosterol, an important c... | |||
T4852 | Trimyristin | Trimyristoylglycerol,Tritetradecanoin,Glyceryl trimyristate,1,2,3-Tritetradecanoylglycerol | Phosphatase , Endogenous Metabolite , AChE |
Trimyristin (Tritetradecanoin) is primarily located in the membrane (predicted from logP) and adiposome. glyceryl trimyristate exists in all eukaryotes, ranging from yeast to humans. In humans, glyceryl trimyristate is i... | |||
T1379 | L-5-Hydroxytryptophan | L-oxitriptan,Oxitriptan,L-5-HTP | Amino Acids and Derivatives , Endogenous Metabolite |
L-5-Hydroxytryptophan (L-5-HTP) is the immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant. | |||
T4939 | Indole-3-pyruvic acid | 3-(3-Indolyl)-2-oxopropanoic acid | Others |
Indole-3-pyruvic acid (3-(3-Indolyl)-2-oxopropanoic acid) is a compound involved in the biosynthesis of Indole-3-acetic acid, a plant hormone which plays important roles in regulating growth and responses to environmenta... | |||
T1468 | Lornoxicam | Ro 13-9297,Chlortenoxicam,TS110 | COX , Endogenous Metabolite |
Lornoxicam (Chlortenoxicam) (chlortenoxicam) is a new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory, and antipyretic properties. Lornoxicam differs from other oxicam co... | |||
------------------------ More ------------------------ |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-03525 | Cap5A Protein, S. aureus, Recombinant (His) | Staphylococcus aureus | in vitro E. coli expression system |
Required for the biosynthesis of type 5 capsular polysaccharide (Cap5/CP5). Might act as the chain-length regulator. | |||
TMPH-00188 | BioAB Protein, Bacteroides fragilis, Recombinant (His & Myc) | Bacteroides fragilis | E. coli |
BioAB Protein, Bacteroides fragilis, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPJ-00932 | PBLD Protein, Human, Recombinant (His) | Human | E. coli |
Phenazine Biosynthesis-Like Domain-Containing protein (PBLD) belongs to the phenazine biosynthesis-like protein (PhzF) family, which is expressed in most tissues. PBLD takes part in the MAPK signaling pathway, and is inv... | |||
TMPY-01736 | COX-2 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
PTGS2, also known as COX-2, is s component of Prostaglandin-endoperoxide synthase (PTGS). PTGS, also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a perox... | |||
TMPY-00392 | PAM Protein, Human, Recombinant (His) | Human | HEK293 |
Peptidylglycine alpha-amidating monooxygenase (PAM) is highly expressed in neurons and endocrine cells, where it catalyzes one of the final steps in the biosynthesis of bioactive peptides. PAM is also expressed in unicel... | |||
TMPY-03156 | VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, His) | Mouse,Rat | HEK293 |
Vascular endothelial growth factor C (VEGF-C) is a member of the VEGF family. Upon biosynthesis, VEGF-C protein is secreted as a non-covalent momodimer in an anti-parellel fashion. VEGF-C protein is a dimeric glycoprotei... | |||
TMPY-01007 | VEGFC Protein, Human, Recombinant (His) | Human | HEK293 |
Vascular endothelial growth factor C (VEGF-C) is a member of the VEGF family. Upon biosynthesis, VEGF-C protein is secreted as a non-covalent momodimer in an anti-parellel fashion. VEGF-C protein is a dimeric glycoprotei... | |||
TMPY-01460 | ABHD4 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Abhydrolase domain containing 4 (ABHD4), also known as alpha/beta-hydrolase 4 (ABH4) , or lyso-N-acylphosphatidylethanolamine lipase, which belongs to the ABHD4/ABHD5 subfamily of peptidase S33 family. Abhydrolase domain... | |||
TMPY-02371 | ST6GAL1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Beta-galactoside alpha-2,6-sialyltransferase 1, also known as B-cell antigen CD75, Sialyltransferase 1, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1, ST6GAL1 and SIAT1, is a single-pass type I... | |||
TMPY-02801 | PHGDH Protein, Human, Recombinant (His) | Human | E. coli |
PHGDH is a member of the D-isomer specific 2-hydroxyacid dehydrogenase family. This new family consists of D-isomer-stereospecific enzymes. The conserved residues in this family appear to be the residues involved in the ... | |||
TMPY-02779 | Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His) | Human | Baculovirus-Insect Cells |
Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoant... | |||
TMPH-00591 | SpeA Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Catalyzes the biosynthesis of agmatine from arginine. | |||
TMPH-03584 | Shikimate dehydrogenase Protein, S. epidermidis, Recombinant (His & Myc) | Staphylococcus epidermidis | E. coli |
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). It can also u... | |||
TMPH-01395 | QPCTL Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Responsible for the biosynthesis of pyroglutamyl peptides. | |||
TMPH-02293 | UGDH Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Catalyzes the formation of UDP-alpha-D-glucuronate, a constituent of complex glycosaminoglycans. Required for the biosynthesis of chondroitin sulfate and heparan sulfate. Required for embryonic development via its role i... | |||
TMPH-00795 | Glutamate racemase Protein, Helicobacter pylori, Recombinant (His & Myc) | Helicobacter pylori | E. coli |
Provides the (R)-glutamate required for cell wall biosynthesis. | |||
TMPH-00572 | ACP Protein, E. coli, Recombinant (His & SUMO) | E. coli | E. coli |
Carrier of the growing fatty acid chain in fatty acid biosynthesis. | |||
TMPH-01812 | SEPSECS Protein, Human, Recombinant (His) | Human | Yeast |
Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. | |||
TMPH-01813 | SEPSECS Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. | |||
TMPH-02652 | FGF-15 Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression. | |||
TMPH-00563 | 3-demethoxyubiquinol 3-hydroxylase Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Catalyzes the hydroxylation of 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis. | |||
TMPH-02958 | Tryptophan Hydroxylase 1 Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Oxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis. | |||
TMPH-03402 | STR1 Protein, Rauvolfia serpentina, Recombinant (His & Myc) | Rauvolfia serpentina | E. coli |
Catalyzes the stereospecific condensation of tryptamine with secologanin to form strictosidine, the key intermediate of indole alkaloid biosynthesis. | |||
TMPH-00019 | BlaNDM-1 Protein, Acinetobacter baumannii, Recombinant (His & SUMO) | Acinetobacter baumannii | E. coli |
TMPH-00020 | Elongation factor Tu Protein, Acinetobacter baumannii, Recombinant (His) | Acinetobacter baumannii | Yeast |
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. | |||
TMPH-03048 | LpxA Protein, MenC, Recombinant (His) | MenB | E. coli |
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | |||
TMPH-03518 | ACP Protein, S. aureus, Recombinant (GST) | Staphylococcus aureus | E. coli |
Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced. | |||
TMPH-03520 | ACP Protein, S. aureus, Recombinant (His & SUMO) | Staphylococcus aureus | E. coli |
Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced. | |||
TMPY-00481 | AKR1C4 Protein, Human, Recombinant (His) | Human | E. coli |
Aldo-keto reductases comprise of AKR1C1-AKR1C4, four enzymes that catalyze NADPH dependent reductions and have been implicated in biosynthesis, intermediary metabolism, and detoxification. there is a strong correlation ... | |||
TMPH-03519 | ACP Protein, S. aureus, Recombinant (His) | Staphylococcus aureus | Yeast |
Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced. | |||
TMPH-03447 | ERG11 Protein, S. cerevisiae, Recombinant (GST) | Saccharomyces cerevisiae | E. coli |
Catalyzes C14-demethylation of lanosterol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol. | |||
TMPH-03453 | GPI3 Protein, S. cerevisiae, Recombinant (His & Myc) | Saccharomyces cerevisiae | E. coli |
Catalytic subunit in the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. | |||
TMPH-00024 | LpxC Protein, Acinetobacter baumannii, Recombinant (His) | Acinetobacter baumannii | E. coli |
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. | |||
TMPH-03179 | LpxC Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO) | Pseudomonas aeruginosa | E. coli |
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. | |||
TMPH-02378 | LpxC Protein, Klebsiella pneumoniae, Recombinant (His & Myc) | Klebsiella pneumoniae | E. coli |
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. | |||
TMPH-03180 | LpxC Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) | Pseudomonas aeruginosa | E. coli |
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. | |||
TMPH-00555 | LpxC Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. | |||
TMPH-00564 | FabG Protein, E. coli, Recombinant (His & Myc) | E. coli | E. coli |
Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. | |||
TMPH-00691 | IscS Protein, E. coli O6:K15:H31, Recombinant (His & Myc & SUMO) | E. coli | E. coli |
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur and selenium atoms from cysteine and sel... | |||
TMPH-02680 | QPCT Protein, Mouse, Recombinant (His & Myc) | Mouse | HEK293 |
Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue... | |||
TMPH-03017 | CYP51 Protein, Mycobacterium tuberculosis, Recombinant (His & Myc) | Mycobacterium tuberculosis | Baculovirus |
Its precise biological substrate is not known. Catalyzes C14-demethylation of lanosterol, 24,25-dihydrolanosterol and obtusifoliol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'-dimethy... | |||
TMPH-02679 | QPCT Protein, Mouse, Recombinant (His) | Mouse | Yeast |
Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue... | |||
TMPJ-01265 | PPC-DC Protein, Human, Recombinant (aa 1-204, His) | Human | E. coli |
Phosphopantothenoylcysteine Decarboxylase (PPC-DC) is an essential enzyme in the biosynthesis ofCoenzyme A and catalyzes the decarboxylation of PPC to Phosphopantetheine. PPC-DC catalyzes the decarboxylation of the Cyste... | |||
TMPH-00602 | MetC Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Primarily catalyzes the cleavage of cystathionine to homocysteine, pyruvate and ammonia during methionine biosynthesis. Also exhibits cysteine desulfhydrase activity, producing sulfide from cysteine. In addition, under c... | |||
TMPJ-00473 | QPRTase Protein, Human, Recombinant (His) | Human | E. coli |
Nicotinate-Nucleotide Pyrophosphorylase (QPRT) belongs to the nadC/modD family. QPRT plays an improtant role in catabolism of quinolinate which acts as a potent endogenous exitotoxin to neurons. In addition, QPRT serves ... | |||
TMPY-03452 | PTS Protein, Human, Recombinant (His) | Human | E. coli |
PTS(6-pyruvoyltetrahydropterin synthase) belongs to the PTPS family. It catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesi... | |||
TMPH-02491 | SCD1 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond at the Delta-9... | |||
TMPY-01948 | COQ7 Protein, Human, Recombinant (His) | Human | HEK293 |
Ubiquinone biosynthesis protein COQ7 homolog, also known as Coenzyme Q biosynthesis protein 7 homolog, Timing protein clk-1 homolog and COQ7, is a mitochondrion inner membrane and peripheral membrane protein which bel... | |||
TMPH-01603 | Lanosterol synthase/LSS Protein, Human, Recombinant (His) | Human | E. coli |
Key enzyme in the cholesterol biosynthesis pathway. Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. Through the production of lanosterol may regulate lens prote... | |||
TMPY-06352 | ALDH1A3 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Aldehyde dehydrogenase 1 family, member A3 (ALDH1A3), also known as Retinaldehyde dehydrogenase 3 (RALDH3), which belongs to the aldehyde dehydrogenase family. ALDH1A3 is a novel Cancer stem cell (CSC) marker with potent... | |||
------------------------ More ------------------------ |
Cat No. | Product Name | ||
---|---|---|---|
L6120 | Flavonoid Natural Product Library | 477 compounds | |
A unique collection of 477 flavonoids can be used for high throughput and high content screening; | |||
L9820 | Beta-Lactam Compound Library | 105 compounds | |
A unique collection of 105 beta-lactam compounds, can be used in HTS and HCS; | |||
L7000 | Bioactive Lipid Compound Library | 385 compounds | |
A unique collection of 385 bioactive lipids related compounds for high throughput screening (HTS) and high content screening (HCS), including Agonists & Antagonists, Endocannabinoids, Farnesyl/geranylgeranyl derivates, ... | |||
L9700 | Endoplasmic Reticulum Stress Compound Library | 193 compounds | |
A unique collection of 193 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS); | |||
L2550 | Glutamine Metabolism Compound Library | 580 compounds | |
A unique collection of 580 glutamine metabolism related compounds can be used for high throughput screening (HTS) and high content screening (HCS), and also is an effective tool for research in glutamine metabolism and ... |