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Potassium Channel

Potassium Channels. K+ channels are membrane proteins that allow rapid and selective flow of K+ ions across the cell membrane, and thus generate electrical signals in cells. Voltage-gated K+ channels (Kv channels), present in all animal cells, open and close upon changes in the transmembrane potential.
Cat. No. Product name CAS No. Purity Chemical Structure
T27753 KT-362 fumarate 105394-80-7 98%
KT-362 fumarate is a novel compound that acts as an antagonist of calcium channels, potassium channels and sodium channels.KT-362 fumarate causes vasodilation by...
T72066 CHET3 2489231-47-0 98%
CHET3 is a TASK-3 inhibitor that can be used to study pain.
T3465L Vesnarinone HCl T3465L 98%
Vesnarinone HCl is an orally active phosphodiesterase 3 (PDE3) inhibitor.Vesnarinone HCl modulates calcium and potassium ions, increasing calcium flux and decrea...
T16444 PD-118057 313674-97-4 98%
PD-118057 is a potent ether associated (hERG) potassium channel activator that shows no activity against hERG. PD-118057 inhibits the excitability of the membran...
T68038 Celivarone 401925-43-7 98%
Celivarone is a potassium channel blocker used in the study of arrhythmias, atrial flutter and atrial fibrillation.
T30520 BMS-394136 343246-73-1 98%
BMS-394136 is a KV1.5 antagonist for the treatment of cardiovascular diseases such as arrhythmias and atrial fibrillation.
T32873 Maralixibat Chloride 228113-66-4 98%
Maralixibat Chloride, an apical, sodium-dependent, bile acid transport inhibitor, prevents enterohepatic bile acid recirculation.
T2434 LY 303511 154447-38-8 98%
LY303511, an inactive analogue of LY294002, is a mTOR inhibitor and no inhibition for PI3-K.
TN3910 Ecdysone 3604-87-3 98%
Ecdysone signaling through Ecdysone receptor isoform B1 is required cell autonomously for the muscle death. A nctional Bombyx Ecdysone receptor binds to EcRE-D a...
T8182 Guanfu base A 1394-48-5 98%
Guanfu base A is a potent noncompetitive CYP2D6 inhibitor (Ki: 1.20 μM in HLMs; Ki: 0.37 μM for rCYP2D6). It also inhibits HERG channel current.
TN3042 4-Hydroxycinnamamide 194940-15-3 98%
4-Hydroxycinnamamide has antioxidant activity. 4-Hydroxycinnamamide derivatives are specific inhibitors of tyrosine-specific protein kinases.
TMA0763 Methyl 3,4,5-trimethoxycinnamate 7560-49-8 98%
Methyl 3,4,5-trimethoxycinnamate may protect the heart from arrhythmias via its inhibitory effect on calcium channel.
TN3460 Asebogenin 520-42-3 98%
Asebogenin has anti-bacterial activity, it shows inhibitory activity against S. aureus and methicillin-resistant S. aureus (IC50 of 10 and 4.5 micrograms/ml, res...
TP1852 Myomodulin 110570-93-9 98%
Myomodulin is a neuropeptide present in molluscs, insects, and gastropods.Myomodulin is present in two identified aplysia neurons that contain myomodulin A the A...
TN3319 9-Hydroxycanthin-6-one 138544-91-9 98%
9-Hydroxycanthin-6-one might be the active component that contributed to the aphrodisiac effect of E. longifolia by antagonizing the smooth muscle tone of CC as ...
TQ0307 Vernakalant 794466-70-9 98%
Vernakalant (RSD-1235) is a mixed ion channel blocker.
T14040 4-Hydroxytolbutamide 5719-85-7 98%
4-Hydroxytolbutamide(Hydroxytolbutamide), a metabolite of Tolbutamide, which is metabolized by CYP2C8 and CYP2C9. Tolbutamide is a first generation potassium cha...
TN4697 Odoroside H 18810-25-8 98%
Odoroside H has anticancer activities, the cytotoxic effects are induced by the inhibition of the plasma membrane bound Na(+)/K(+)-ATPase.
TN5141 Thevetin B 27127-79-3 98%
Thevetin B is a cardiac glycoside and an inhibitor of Na+-, K+-dependent adenosinetriphosphatase (Na+,K+-ATPase) from Thevetia peruviana.
TN3636 Chlorahololide C 1007859-25-7 98%
Chlorahololide C is a potent and selective potassium channel blocker, it exerts potent and selective inhibition on the delayed rectifier (I(K)) K(+) current with...
KT-362 fumarate
T27753
KT-362 fumarate is a novel compound that acts as an antagonist of calcium channels, potassium channels and sodium channels.KT-362 fumarate causes vasodilation by...
CHET3
T72066
CHET3 is a TASK-3 inhibitor that can be used to study pain.
Vesnarinone HCl
T3465L
Vesnarinone HCl is an orally active phosphodiesterase 3 (PDE3) inhibitor.Vesnarinone HCl modulates calcium and potassium ions, increasing calcium flux and decrea...
PD-118057
T16444
PD-118057 is a potent ether associated (hERG) potassium channel activator that shows no activity against hERG. PD-118057 inhibits the excitability of the membran...
Celivarone
T68038
Celivarone is a potassium channel blocker used in the study of arrhythmias, atrial flutter and atrial fibrillation.
BMS-394136
T30520
BMS-394136 is a KV1.5 antagonist for the treatment of cardiovascular diseases such as arrhythmias and atrial fibrillation.
Maralixibat Chloride
T32873
Maralixibat Chloride, an apical, sodium-dependent, bile acid transport inhibitor, prevents enterohepatic bile acid recirculation.
LY 303511
T2434
LY303511, an inactive analogue of LY294002, is a mTOR inhibitor and no inhibition for PI3-K.
Ecdysone
TN3910
Ecdysone signaling through Ecdysone receptor isoform B1 is required cell autonomously for the muscle death. A nctional Bombyx Ecdysone receptor binds to EcRE-D a...
Guanfu base A
T8182
Guanfu base A is a potent noncompetitive CYP2D6 inhibitor (Ki: 1.20 μM in HLMs; Ki: 0.37 μM for rCYP2D6). It also inhibits HERG channel current.
4-Hydroxycinnamamide
TN3042
4-Hydroxycinnamamide has antioxidant activity. 4-Hydroxycinnamamide derivatives are specific inhibitors of tyrosine-specific protein kinases.
Methyl 3,4,5-trimethoxycinnamate
TMA0763
Methyl 3,4,5-trimethoxycinnamate may protect the heart from arrhythmias via its inhibitory effect on calcium channel.
Asebogenin
TN3460
Asebogenin has anti-bacterial activity, it shows inhibitory activity against S. aureus and methicillin-resistant S. aureus (IC50 of 10 and 4.5 micrograms/ml, res...
Myomodulin
TP1852
Myomodulin is a neuropeptide present in molluscs, insects, and gastropods.Myomodulin is present in two identified aplysia neurons that contain myomodulin A the A...
9-Hydroxycanthin-6-one
TN3319
9-Hydroxycanthin-6-one might be the active component that contributed to the aphrodisiac effect of E. longifolia by antagonizing the smooth muscle tone of CC as ...
Vernakalant
TQ0307
Vernakalant (RSD-1235) is a mixed ion channel blocker.
4-Hydroxytolbutamide
T14040
4-Hydroxytolbutamide(Hydroxytolbutamide), a metabolite of Tolbutamide, which is metabolized by CYP2C8 and CYP2C9. Tolbutamide is a first generation potassium cha...
Odoroside H
TN4697
Odoroside H has anticancer activities, the cytotoxic effects are induced by the inhibition of the plasma membrane bound Na(+)/K(+)-ATPase.
Thevetin B
TN5141
Thevetin B is a cardiac glycoside and an inhibitor of Na+-, K+-dependent adenosinetriphosphatase (Na+,K+-ATPase) from Thevetia peruviana.
Chlorahololide C
TN3636
Chlorahololide C is a potent and selective potassium channel blocker, it exerts potent and selective inhibition on the delayed rectifier (I(K)) K(+) current with...
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