Potassium Channel

Potassium Channels. K+ channels are membrane proteins that allow rapid and selective flow of K+ ions across the cell membrane, and thus generate electrical signals in cells. Voltage-gated K+ channels (Kv channels), present in all animal cells, open and close upon changes in the transmembrane potential.

Cat. No.	Product name	CAS No.	Purity
T27753	KT-362 fumarate	105394-80-7	98%
T27753	KT-362 fumarate is a novel compound that acts as an antagonist of calcium channels, potassium channels and sodium channels.KT-362 fumarate causes vasodilation by...
T72066	CHET3	2489231-47-0	98%
T72066	CHET3 is a TASK-3 inhibitor that can be used to study pain.
T3465L	Vesnarinone HCl	T3465L	98%
T3465L	Vesnarinone HCl is an orally active phosphodiesterase 3 (PDE3) inhibitor.Vesnarinone HCl modulates calcium and potassium ions, increasing calcium flux and decrea...
T16444	PD-118057	313674-97-4	98%
T16444	PD-118057 is a potent ether associated (hERG) potassium channel activator that shows no activity against hERG. PD-118057 inhibits the excitability of the membran...
T68038	Celivarone	401925-43-7	98%
T68038	Celivarone is a potassium channel blocker used in the study of arrhythmias, atrial flutter and atrial fibrillation.
T30520	BMS-394136	343246-73-1	98%
T30520	BMS-394136 is a KV1.5 antagonist for the treatment of cardiovascular diseases such as arrhythmias and atrial fibrillation.
T32873	Maralixibat Chloride	228113-66-4	98%
T32873	Maralixibat Chloride, an apical, sodium-dependent, bile acid transport inhibitor, prevents enterohepatic bile acid recirculation.
T2434	LY 303511	154447-38-8	98%
T2434	LY303511, an inactive analogue of LY294002, is a mTOR inhibitor and no inhibition for PI3-K.
TN3910	Ecdysone	3604-87-3	98%
TN3910	Ecdysone signaling through Ecdysone receptor isoform B1 is required cell autonomously for the muscle death. A nctional Bombyx Ecdysone receptor binds to EcRE-D a...
T8182	Guanfu base A	1394-48-5	98%
T8182	Guanfu base A is a potent noncompetitive CYP2D6 inhibitor (Ki: 1.20 μM in HLMs; Ki: 0.37 μM for rCYP2D6). It also inhibits HERG channel current.
TN3042	4-Hydroxycinnamamide	194940-15-3	98%
TN3042	4-Hydroxycinnamamide has antioxidant activity. 4-Hydroxycinnamamide derivatives are specific inhibitors of tyrosine-specific protein kinases.
TMA0763	Methyl 3,4,5-trimethoxycinnamate	7560-49-8	98%
TMA0763	Methyl 3,4,5-trimethoxycinnamate may protect the heart from arrhythmias via its inhibitory effect on calcium channel.
TN3460	Asebogenin	520-42-3	98%
TN3460	Asebogenin has anti-bacterial activity, it shows inhibitory activity against S. aureus and methicillin-resistant S. aureus (IC50 of 10 and 4.5 micrograms/ml, res...
TP1852	Myomodulin	110570-93-9	98%
TP1852	Myomodulin is a neuropeptide present in molluscs, insects, and gastropods.Myomodulin is present in two identified aplysia neurons that contain myomodulin A the A...
TN3319	9-Hydroxycanthin-6-one	138544-91-9	98%
TN3319	9-Hydroxycanthin-6-one might be the active component that contributed to the aphrodisiac effect of E. longifolia by antagonizing the smooth muscle tone of CC as ...
TQ0307	Vernakalant	794466-70-9	98%
TQ0307	Vernakalant (RSD-1235) is a mixed ion channel blocker.
T14040	4-Hydroxytolbutamide	5719-85-7	98%
T14040	4-Hydroxytolbutamide(Hydroxytolbutamide), a metabolite of Tolbutamide, which is metabolized by CYP2C8 and CYP2C9. Tolbutamide is a first generation potassium cha...
TN4697	Odoroside H	18810-25-8	98%
TN4697	Odoroside H has anticancer activities, the cytotoxic effects are induced by the inhibition of the plasma membrane bound Na(+)/K(+)-ATPase.
TN5141	Thevetin B	27127-79-3	98%
TN5141	Thevetin B is a cardiac glycoside and an inhibitor of Na+-, K+-dependent adenosinetriphosphatase (Na+,K+-ATPase) from Thevetia peruviana.
TN3636	Chlorahololide C	1007859-25-7	98%
TN3636	Chlorahololide C is a potent and selective potassium channel blocker, it exerts potent and selective inhibition on the delayed rectifier (I(K)) K(+) current with...