T27753 |
KT-362 fumarate
|
105394-80-7
|
98%
|
|
KT-362 fumarate is a novel compound that acts as an antagonist of calcium channels, potassium channels and sodium channels.KT-362 fumarate causes vasodilation by...
|
T72066 |
CHET3
|
2489231-47-0
|
98%
|
|
CHET3 is a TASK-3 inhibitor that can be used to study pain.
|
T3465L |
Vesnarinone HCl
|
T3465L
|
98%
|
|
Vesnarinone HCl is an orally active phosphodiesterase 3 (PDE3) inhibitor.Vesnarinone HCl modulates calcium and potassium ions, increasing calcium flux and decrea...
|
T16444 |
PD-118057
|
313674-97-4
|
98%
|
|
PD-118057 is a potent ether associated (hERG) potassium channel activator that shows no activity against hERG. PD-118057 inhibits the excitability of the membran...
|
T68038 |
Celivarone
|
401925-43-7
|
98%
|
|
Celivarone is a potassium channel blocker used in the study of arrhythmias, atrial flutter and atrial fibrillation.
|
T30520 |
BMS-394136
|
343246-73-1
|
98%
|
|
BMS-394136 is a KV1.5 antagonist for the treatment of cardiovascular diseases such as arrhythmias and atrial fibrillation.
|
T32873 |
Maralixibat Chloride
|
228113-66-4
|
98%
|
|
Maralixibat Chloride, an apical, sodium-dependent, bile acid transport inhibitor, prevents enterohepatic bile acid recirculation.
|
T2434 |
LY 303511
|
154447-38-8
|
98%
|
|
LY303511, an inactive analogue of LY294002, is a mTOR inhibitor and no inhibition for PI3-K.
|
TN3910 |
Ecdysone
|
3604-87-3
|
98%
|
|
Ecdysone signaling through Ecdysone receptor isoform B1 is required cell autonomously for the muscle death. A nctional Bombyx Ecdysone receptor binds to EcRE-D a...
|
T8182 |
Guanfu base A
|
1394-48-5
|
98%
|
|
Guanfu base A is a potent noncompetitive CYP2D6 inhibitor (Ki: 1.20 μM in HLMs; Ki: 0.37 μM for rCYP2D6). It also inhibits HERG channel current.
|
TN3042 |
4-Hydroxycinnamamide
|
194940-15-3
|
98%
|
|
4-Hydroxycinnamamide has antioxidant activity. 4-Hydroxycinnamamide derivatives are specific inhibitors of tyrosine-specific protein kinases.
|
TMA0763 |
Methyl 3,4,5-trimethoxycinnamate
|
7560-49-8
|
98%
|
|
Methyl 3,4,5-trimethoxycinnamate may protect the heart from arrhythmias via its inhibitory effect on calcium channel.
|
TN3460 |
Asebogenin
|
520-42-3
|
98%
|
|
Asebogenin has anti-bacterial activity, it shows inhibitory activity against S. aureus and methicillin-resistant S. aureus (IC50 of 10 and 4.5 micrograms/ml, res...
|
TP1852 |
Myomodulin
|
110570-93-9
|
98%
|
|
Myomodulin is a neuropeptide present in molluscs, insects, and gastropods.Myomodulin is present in two identified aplysia neurons that contain myomodulin A the A...
|
TN3319 |
9-Hydroxycanthin-6-one
|
138544-91-9
|
98%
|
|
9-Hydroxycanthin-6-one might be the active component that contributed to the aphrodisiac effect of E. longifolia by antagonizing the smooth muscle tone of CC as ...
|
TQ0307 |
Vernakalant
|
794466-70-9
|
98%
|
|
Vernakalant (RSD-1235) is a mixed ion channel blocker.
|
T14040 |
4-Hydroxytolbutamide
|
5719-85-7
|
98%
|
|
4-Hydroxytolbutamide(Hydroxytolbutamide), a metabolite of Tolbutamide, which is metabolized by CYP2C8 and CYP2C9. Tolbutamide is a first generation potassium cha...
|
TN4697 |
Odoroside H
|
18810-25-8
|
98%
|
|
Odoroside H has anticancer activities, the cytotoxic effects are induced by the inhibition of the plasma membrane bound Na(+)/K(+)-ATPase.
|
TN5141 |
Thevetin B
|
27127-79-3
|
98%
|
|
Thevetin B is a cardiac glycoside and an inhibitor of Na+-, K+-dependent adenosinetriphosphatase (Na+,K+-ATPase) from Thevetia peruviana.
|
TN3636 |
Chlorahololide C
|
1007859-25-7
|
98%
|
|
Chlorahololide C is a potent and selective potassium channel blocker, it exerts potent and selective inhibition on the delayed rectifier (I(K)) K(+) current with...
|