T79359 |
Anticancer agent 147
|
2241283-11-2
|
98%
|
|
Compound 6j (Anticancer agent 147), a sophoridine derivative and ferroptosis inducer, promotes intracellular accumulation of Fe2+, reactive oxygen species (ROS),...
|
T79639 |
Lepadin H
|
412328-25-7
|
98%
|
|
Lepadin H, a marine alkaloid and ferroptosis inducer, exhibits significant cytotoxicity by promoting p53 expression, escalating ROS production, and enhancing lip...
|
T79777 |
GPX4-IN-7
|
|
98%
|
|
GPX4-IN-7 (Compound 31), an indirubin derivative, serves as a ferroptosis inducer in colon cancer treatment. Exhibiting potent antitumor properties, it inhibits ...
|
T79945 |
Ferroptosis-IN-1
|
|
98%
|
|
Ferroptosis-IN-1, a diterpene derived from A. campylantha, functions as a ferroptosis inhibitor with an EC50 of 10 μM and is utilized in the study of neuroinflam...
|
T82408 |
Ferroptosis-IN-3
|
|
98%
|
|
Ferroptosis-IN-3 (Compound 25), a ferroptosis inhibitor, demonstrates potent activity by inhibiting RSL3-induced ferroptosis in HT-1080 cells (EC50: 8.6 nM). It ...
|
T1565 |
Deferiprone
|
30652-11-0
|
99.97%
|
|
Deferiprone (Deferidone) is an Iron Chelator. The mechanism of action of deferiprone is as an Iron Chelating Activity.
|
T0877 |
Gallic acid
|
149-91-7
|
99.95%
|
|
Gallic acid (Benzoic acid) is found in almost all plants. Plants known for their high gallic acid content include gallnuts,grapes,tea,hops and oak bark.
|
T0687 |
Simvastatin
|
79902-63-9
|
99.95%
|
|
Simvastatin (MK 733) is a HMG-CoA Reductase Inhibitor. The mechanism of action of simvastatin is as a Hydroxymethylglutaryl-CoA Reductase Inhibitor.
|
T6468 |
D-glutamine
|
5959-95-5
|
99.92%
|
|
D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code.
|
T0433 |
Artesunate
|
88495-63-0
|
99.91%
|
|
Artesunate (WR-256283) is part of the artemisinin group of drugs that treat malaria. It is a semi-synthetic derivative of artemisinin that is water-soluble and m...
|
T4309 |
CIL56
|
300802-28-2
|
99.91%
|
|
CIL56 (CA3) is a small molecule that induces cellular ferroptosis through the production of iron-dependent reactive oxygen species (ROS). It also induces accumul...
|
T3116 |
Atorvastatin hemicalcium salt
|
134523-03-8
|
99.89%
|
|
Atorvastatin hemicalcium salt (Atorvastatin Calcium), an effective HMG-CoA reductase inhibitor (IC50 = 8 nM), is utilized as a cholesterol-lowering medication.
|
T0078 |
Lapatinib
|
231277-92-2
|
99.89%
|
|
Lapatinib (GW572016) is a dual inhibitor of Lapatinib is a dual ErbB2/EGFR (IC50: 9.2/10.8 nM) inhibitor
|
T1457 |
Deferasirox
|
201530-41-8
|
99.89%
|
|
Deferasirox (CGP-72670) is an oral iron chelating agent used to treat chronic iron overload.
|
T8662 |
UAMC-3203 hydrochloride
|
2271358-65-5
|
99.87%
|
|
UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.
|
T9073 |
SRS16-86
|
1793052-96-6
|
99.85%
|
|
SRS16-86 is a novel third-generation ferrostatin, is an inhibitor of ferroptosis.
|
T60168 |
NCOA4 - 9a
|
2650557-72-3
|
99.84%
|
|
NCOA4 - 9a is a ferroptosis inhibitor.
|
TQ0211 |
Brusatol
|
14907-98-3
|
99.82%
|
|
Brusatol (NSC-172924) is a natural product isolated from the Brucea javanica plant. It inhibits Nrf2.
|
T3S1447 |
Arteannuin B
|
50906-56-4
|
99.8%
|
|
1. Arteannuin B has potent antimalarial activity.
|
T1637 |
Deferoxamine Mesylate
|
138-14-7
|
99.8%
|
|
Deferoxamine Mesylate (DFOM) is an iron chelator and iron death inhibitor. Deferoxamine Mesylate binds free iron into a stable complex and reduces iron accumulat...
|