Ferroptosis

Ferroptosis is a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides, and is genetically and biochemically distinct from other forms of regulated cell death such as apoptosis.

Cat. No.	Product name	CAS No.	Purity
T60084	FINO2	869298-31-7	98%
T60084	FINO2 is a potent ferroptosis-inducing compound that inhibits GPX4 activity. It functions as a stable oxidant, effectively oxidizing ferrous iron and demonstrati...
T0877	Gallic acid	149-91-7	98%
T0877	Gallic acid is found in almost all plants. Plants known for their high gallic acid content include gallnuts,grapes,tea,hops and oak bark.
T0687	Simvastatin	79902-63-9	98%
T0687	Simvastatin is a HMG-CoA Reductase Inhibitor. The mechanism of action of simvastatin is as a Hydroxymethylglutaryl-CoA Reductase Inhibitor.
T0875	Acetylcysteine	616-91-1	98%
T0875	Acetylcysteine is the N-acetyl derivative of CYSTEINE. It is used as a mucolytic agent to reduce the viscosity of mucous secretions. It has also been shown to ha...
T6468	D-glutamine	5959-95-5	98%
T6468	D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code.
T0433	Artesunate	88495-63-0	98%
T0433	Artesunate is part of the artemisinin group of drugs that treat malaria. It is a semi-synthetic derivative of artemisinin that is water-soluble and may therefore...
T4309	CIL56	300802-28-2	98%
T4309	CIL56 is a small molecule that induces cellular ferroptosis through the production of iron-dependent reactive oxygen species (ROS). It also induces accumulation ...
T0078	Lapatinib	231277-92-2	98%
T0078	Lapatinib is a dual inhibitor of Lapatinib is a dual ErbB2/EGFR (IC50: 9.2/10.8 nM) inhibitor
T9073	SRS16-86	1793052-96-6	98%
T9073	SRS16-86 is a novel third-generation ferrostatin, is an inhibitor of ferroptosis.
TQ0211	Brusatol	14907-98-3	98%
TQ0211	Brusatol is a natural product isolated from the Brucea javanica plant. It inhibits Nrf2.
T0093	Sorafenib tosylate	475207-59-1	98%
T0093	Sorafenib is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf).
T36404L	PRLX-93936 HCL	1094210-96-4	98%
T36404L	PRLX-93936 hcl is an analog of erastin and demonstrated synergistic effects against non-small cell lung cancer (NSCLC) cells with cisplatin.
T6192	Alogliptin	850649-61-5	98%
T6192	Alogliptin(SYR-322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10, 000-fold selectivity over DPP-8 and DPP-9.
T7530	PD146176	4079-26-9	98%
T7530	PD146176 is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM. PD146176 reverses cognitive im...
T64357	FA16		98%
T64357	FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 μM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16 inhibit...
T11631	IFSP1	150651-39-1	98%
T11631	iFSP1 is able to sensitize a variety of human cancer cell lines to the ferroptosis inducer, such as (1S,3R)-RSL3.iFSP1 is a potent, selective and glutathione-ind...
T1847	Necrostatin-1	4311-88-0	98%
T1847	Necrostatin-1 is a specific RIP1 inhibitor and inhibits TNF-α-induced necroptosis (EC50: 490 nM in Jurkat cells).
T1297	Eugenol	97-53-0	98%
T1297	Eugenol is a Standardized Chemical Allergen. The physiologic effect of eugenol is by means of Increased Histamine Release and Cell-mediated Immunity.
T6235	Lapatinib Ditosylate	388082-77-7	98%
T6235	Lapatinib is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).
T2A2497	L-Glutamic acid	56-86-0	98%
T2A2497	(S)-Glutamic acid acts as an excitatory transmitter, shows a direct activating effect on the release of DA from dopaminergic terminals.