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coa

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  • Inhibitors & Agonists
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3-Methylglutaric acid
T4766626-51-7
Methylglutaric acid is a leucine metabolite. A large amount of methylglutaric acid is identified in urine of patients with deficiency of 3-methylglutaconyl coenzyme A hydratase (PMID 6181239 ). Methylglutaric acid is also found to be associated with 3-hyd
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Dephospho-CoA
T356593633-59-8
Dephospho-CoA (dpCoA) is an endogenous compound extracted from Escherichia coli and Lactobacillus plantarum, and is an intermediate in coenzyme A biosynthesis.
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Palmitoyl CoA lithium
Palmitoyl coenzyme A lithium
T74038188174-64-3
Palmitoyl CoA lithium (Palmitoyl coenzyme A lithium) is a major component of fatty acids involved in the carnitine shuttle system, beta-oxidation, and the tricarboxylic acid cycle, and can be used to study metabolic disorders in the body.
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7-10 days
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Caffeoyl-CoA
T8279253034-79-0
Caffeoyl-CoA can be isolated from the leaf tissues of Gramineae, exhibiting a Km value of 1.45 μM [1].
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3-Hydroxybutyryl-CoA
TN76042871-66-1
3-Hydroxybutyryl-CoA, a metabolite found in mice, E. coli, and others, contains 3-hydroxybutanoyl as the S-acyl component and serves as an intermediate in butyric acid fermentation and the metabolism of lysine and tryptophan [1].
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4-6 weeks
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CoA-S-S-CoA
TN765631664-36-5
CoA-S-S-CoA, an endogenous metabolite found in *P. furiousus*, serves as a substrate for NOXA2 [1].
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Malonyl CoA tetralithium
Malonyl coenzyme A tetralithium
TN7723116928-84-8
Malonyl CoA tetralithium (Malonyl coenzyme A), serves as a substrate in fatty acid biosynthesis and functions as an inhibitor of fatty acid oxidation. Additionally, it acts as a reversible inhibitor of mitochondrial carnitine palmitoyltransferase (CPT) 1 [1] [2].
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Methylmalonyl-CoA tetralithium
Methylmalonyl coenzyme tetralithium,Isosuccinyl coenzyme A tetralithium
TN7730104809-02-1
Methylmalonyl-CoA tetralithium, also known as Methylmalonyl coenzyme A, serves as a metabolic byproduct derived from the breakdown of valine, isoleucine, methionine, threonine, odd-chain fatty acids, and cholesterol. It is converted into succinyl-CoA through the enzymatic activity of methylmalonyl-CoA mutase (MCM) in the presence of the coenzyme vitamin B12 [1].
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Coatline B
T12403087441-89-2
Coatline B is a useful organic compound for research related to life sciences. The catalog number is T124030 and the CAS number is 87441-89-2.
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Coatline A
T12403187441-88-1
Coatline A is a useful organic compound for research related to life sciences. The catalog number is T124031 and the CAS number is 87441-88-1.
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26-Desglucoavenacoside A
T12458359795-21-0
26-Desglucoavenacoside A is a useful organic compound for research related to life sciences. The catalog number is T124583 and the CAS number is 59795-21-0.
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6-8 weeks
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Glucoalyssin
T124765
Glucoalyssin is a useful organic compound for research related to life sciences and the catalog number is T124765.
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Coagulin L
T125335216164-64-6
Coagulin L is a useful organic compound for research related to life sciences. The catalog number is T125335 and the CAS number is 216164-64-6.
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Licoagroside B
T130375325144-72-7
Licoagroside B is a useful organic compound for research related to life sciences and the catalog number is T130375.
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Licoagrochalcone B
T32742325144-67-0
Licoagrochalcone B is a flavonoid isolated from Patrinia villosa.
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Licoagrochalcone C
T74203325144-68-1
Licoagrochalcone C, a flavonoid compound, demonstrates potent inhibitory effects on NF-κB transcription and significantly reduces LPS-induced NO production, showcasing its bioactive properties [1] [2].
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Glucoamylase
T785019032-08-0
Glucoamylase, an enzyme obtained from various sources such as plants, animals, and microorganisms, is utilized in industrial applications. It is extensively employed in starch saccharification processes and the brewing and distilling industries [1].
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Glucoarabin
T8230567920-64-3
Glucoarabin, a bioactive glucosinolate, upregulates the phase II detoxification enzyme quinone reductase (NQO1) in Hepa1c1c7 cells when hydrolyzed (hGSL 9), without affecting cytochrome P450 (CYP) 1A1 activity [1].
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Licoarylcoumarin
TN4433125709-31-1
Licoarylcoumarin is a strong inhibitor of adenosine 3',5'-cyclic monophosphate (cAMP) phosphodiesterase. Licoarylcoumarin has antibacterial effects on the VRE strains; it has anti-HIV activity, and it has inhibitory effects on xanthine oxidase.
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Secoaristolenedioic acid
TN83982756011-83-1
Secoaristolenedioic acid (Compound 1) is a sesquiterpene identified in the ethanol extract of the roots and rhizomes of Nardostachys chinensis.
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S-Secoantioquine
S-Secoantioquine, Secantioquine
TN896093767-29-4
S-Secoantioquine (Secantioquine) is an open-ring derivative of dibenzylisoquinoline alkaloids. In experiments involving rat striatal membranes, it shows weak displacement activity at the [3H-SCH 23390] binding site but demonstrates some displacement activity at the [3H-raclopride] binding site.
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sterculic acid
T41253738-87-4In house
Sterculic acid, a stearoyl-CoA desaturase-1 (SCD1) inhibitor, effectively suppresses delta-9 desaturase (Δ9D) activity in a dose-dependent manner, exhibiting an inhibition concentration (IC50) value of 0.9 μM [1].
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6-8 weeks
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Mevastatin
ML236B, Compactin
T068373573-88-3
Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum. Mevastatin was the first statin to enter clinical trials.
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Simvastatin
MK-0733, MK 733
T068779902-63-9
Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity. Simvastatin has hypolipidemic activity, inhibits hepatic production of cholesterol, and is also used for the prevention of cardiovascular disease.
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