VEGFR

VEGF receptors are receptors for vascular endothelial growth factor (VEGF). There are three main subtypes of VEGFR, numbered 1, 2 and 3. Also, they may be membrane-bound (mbVEGFR) or soluble (sVEGFR), depending on alternative splicing.

Cat. No.	Product name	CAS No.	Purity
T14677	BMS-690514	859853-30-8	98%
T14677	BMS-690514 is a potent and orally active inhibitor of EGFR and VEGFR. It has IC50s of 5, 20 and 60 nM for EGFR, HER 2 and HER 4, respectively.
TN3587	Capillarisin	56365-38-9	98%
TN3587	Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cell...
T13156	TG 100572	867334-05-2	98%
T13156	TG 100572 is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 ...
TN1867	Licoricidin	30508-27-1	98%
TN1867	Licoricidin, is a potent anti-metastatic agent, which can markedly inhibit the metastatic and invasive capacity of malignant prostate cancer cells.
TQ0080	SU14813 maleate	849643-15-8	98%
TQ0080	SU14813 maleate is an inhibitor of multi-targeted receptor tyrosine kinases (IC50s: 2, 50, 4, 15 nM for VEGFR1, VEGFR2, PDGFRβ, and KIT).
TN4913	Riddelline	23246-96-0	98%
TN4913	Riddelline is a potent genotoxic agent in vitro and induces significant elevations in unscheduled DNA synthesis and S-phase synthesis in rat liver.
T6936	PF-03814735	942487-16-3	98%
T6936	PF-03814735 is a novel, potent and reversible inhibitor of Aurora A/B with IC50of 0.8 nM/5 nM, is less potent to Flt3, FAK, TrkA, and minimally active to Met and...
TN1095	Ginsenoside Rk2	364779-14-6	98%
TN1095	Ginsenoside Rk1 has anti-tumor, and anti-platelet aggregation activities.
TMA1743	Ergosterol peroxide	2061-64-5	98%
TMA1743	Ergosterol peroxide is an inhibitor of osteoclast differentiation, which has antiviral, trypanocidal, antitumor, and antiangiogenic actions, it can stimulate Fox...
TN4748	Penduletin	569-80-2	98%
TN4748	Penduletin has anti-inflammatory,anti-tumor cells, and anti-bacterical activities,it inhibits growth of the Gram-negative pathogen neisseria gonorrhoeae. Pendule...
TN4603	Myricanol	33606-81-4	98%
TN4603	Myricanol can elicit growth inhibitory and cytotoxic effects on lung cancer cells, it can significantly decelerate tumor growth in vivo by inducing apoptosis.
TQ0321	BIBF 1202	894783-71-2	98%
TQ0321	BIBF 1202 is a VEGFR2 kinase inhibitor (IC50: 62 nM).
T13157L	TG 100801 Hydrochloride	1018069-81-2	98%
T13157L	TG 100801 Hydrochloride is a prodrug to treat age-related macular degeneration. TG 100572 is a inhibitor of multi-targeted kinase(IC50s of 2, 7, 2, 16, 13, 5, 0....
TN5250	Vomifoliol	23526-45-6	98%
TN5250	Vomifoliol is most likely the immediate precursor of dehydrovomifoliol, because of the organism converted abscisic acid (ABA), to dehydrovomifoliol as the major ...
T10123	VEGFR-2-IN-9	408502-06-7	98%
T10123	KDR-in-4 is an effective inhibitor of kinase insert domain-containing receptor (KDR/VEGFR2) (IC50: 7 nM).
T13039	Sunitinib-d10	1126721-82-1	98%
T13039	Sunitinib D10 is a deuterium labeled Sunitinib. Sunitinib is a inhibitor of multi-targeted receptor tyrosine kinase(IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ...
TN1567	Delphinidin chloride	528-53-0	98%
TN1567	Delphinidin chloride, a natural plant pigment found in berries and red wine, is a precursor of certain anthocyanins. Delphinidin chloride induces the release of ...
TN5050	Sprengerinin C	88861-91-0	98%
TN5050	Sprengerinin C exerts anti-tumorigenic effects in hepatocellular carcinoma via inhibition of proliferation and angiogenesis and induction of apoptosis, it can st...
T9904	Bevacizumab	216974-75-3	98%
T9904	Ipilimumab anti-CTLA-4) is an immunomodulatory monoclonal antibody directed against the cell surface antigen CTLA-4 and also a type of immune checkpoint inhibito...
TN5100	Taspine	602-07-3	98%
TN5100	Taspine shows antitumor activity by modulating the EGFR signaling pathway of Erk1/2 and Akt in vitro and in vivo, it can inhibit growth and induce apoptosis of H...