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Search Results for " parp "

Targets

182

Compounds

26

Natural Products

13

Recombinant Proteins

2

Libraries

Cat No. Product Name Synonyms Targets
T12365 PARP/PI3K-IN-1 PARP , PI3K
PARP/PI3K-IN-1 is a novel dual poly (ADP-ribose) polymerase (PARP) and phosphatidylinositol 3-kinase (PI3K) dual inhibitor with anticancer, antitumour and antiproliferative activities for the study of breast, pancreatic ...
T78182 PARP-1-IN-4 Others , PARP
PARP-1-IN-4 is a potent PARP-1 inhibitor with potential see anti-tumor activity, and inhibition of PARP-1 may be used in cancer development.
T62281 PARP-1-IN-2 PARP
PARP-1-IN-2 is a potent PARP1 inhibitor that crosses the blood-brain barrier (IC50: 149 nM).PARP-1-IN-2 showed significant antiproliferative activity against the human lung adenocarcinoma epithelial cell line A549 in cel...
T78157 PARP-1-IN-3 Apoptosis , PARP
PARP-1-IN-3 is a potent PARP-1 inhibitor that inhibits PARP-1 and PARP-2 with IC50 values of 0.25 nM and 2.34 nM, respectively.PARP-1-IN-3 has potential anti-inflammatory activity, induces apoptosis, and arrests the cell...
T40310 PARP/EZH2-IN-1 PARP/EZH2-IN-1
PARP/EZH2-IN-1 is a novel compound that functions as a dual inhibitor for both PARP (IC50 6.87 nM) and EZH2 (IC50 36.51 nM), showing promising potential for the treatment of triple-negative breast cancer with wild-type B...
T73027 PARP-2-IN-3 Apoptosis , PARP
PARP-2-IN-3 is used as a potent PARP-2 inhibitor (IC50=0.07 μM) with anti-tumor activity that induces apoptosis and necrosis in cancer cells, and can be used for the study of breast cancer.CAS 번호128-52-56-8
T6329 3-Aminobenzamide 3-AB,INO1001,INO-1001,3-ABA,PARP-IN-1,INO 1001 PARP
3-Aminobenzamide (PARP-IN-1) is an effective inhibitor of PARP (IC50<50 nM in CHO cells) and a mediator of oxidant-induced myocyte dysfunction during reperfusion.
T12364 PARP-2-IN-1 Others
PARP-2-IN-1 is a potent and selective inhibitor of PARP-2(IC50 of 11.5 nM).
T72862 PARP-2/1-IN-2
PARP-2/1-IN-2, an enantiomer of Veliparib, serves as a potent inhibitor of PARP, demonstrating inhibition constants (Kis) of 2 nM for PARP-2 and 5 nM for PARP-1. This compound exhibits a half-maximal effective concentrat...
T79330 PARP-1-IN-13 PARP
PARP-1-IN-13 (Compound 19c) is a potent PARP-1 inhibitor with an IC50 of 26 nM, hindering DNA single-strand break repair and exacerbating DNA double-strand breaks. It induces apoptosis in cancer cells via the mitochondri...
T61798 PARP-1-IN-1
PARP-1-IN-1 is a highly selective and orally active inhibitor of the enzyme PARP-1, with an IC50 value of 0.96 nM. It exhibits excellent tolerance and demonstrates significant activity in a single dose in the MDA-MB-436 ...
T62508 PARP-1/2-IN-1
PARP-1-/2-IN-1 is a potent inhibitor of PARP-1 (IC50: 0.51 nM) and PARP-2 (IC50: 23.11 nM).
T61962 PARP-1/HDAC-IN-1
PARP-1/HDAC-IN-1 is an effective dual inhibitor of PARP-1/HDAC6, with IC50 of 68.90 nM and 510 nM respectively. PARP-1/HDAC-IN-1 has anti-cancer, anti-migration and anti-angiogenesis activities.
T79647 VEGFR/PARP-IN-1 PARP
VEGFR/PARP-IN-1 (Compound 14b) is a dual inhibitor of VEGFR and PARP with IC50 values of 191 nM and 60.9 nM, respectively. It impairs DNA damage repair pathways, promotes apoptosis, and halts cells in the G2/M phase. Thi...
T74173 PROTAC PARP/EGFR ligand 1
PROTAC PARP/EGFR ligand 1 is a potent compound utilized in the creation of dual PARP-EGFR degraders through Proteolytic Targeting Chimera (PROTAC) technology [1].
T78787 PARP-1/2-IN-2 PARP
PARP-1/2-IN-2-IN-1 (Compound 12e) effectively inhibits PARP1/2 and CDK12 with IC 50 values of 34 nM, 30 nM, and 285 nM respectively, impairing DNA damage repair and inducing cell cycle arrest and apoptosis. This compound...
T9610 PARP1-IN-5 dihydrochloride  PARP
PARP1-IN-5 dihydrochloride is an orally active, potent and selective PARP-1 inhibitor (IC50 =14.7 nM). PARP1-IN-5 dihydrochloride can be used for the research of cancer.
T16761 RK-287107 Others , PARP
RK-287107 is an effective and specific inhibitor of tankyrase (IC50s: 14.3 and 10.6 nM for tankyrase-1 and tankyrase-2, respectively).
T8964 G244-LM Others , PARP
G244-LM is a potent and specific inhibitor of tankyrase 1/2. G244-LM inhibits Wnt signaling.
T1807 JW 55 JW55 PARP , Wnt/beta-catenin
JW 55 (JW55) is an effective and selective β-catenin signaling pathway inhibitor, works by inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2).
T15639 K-756 PARP , Wnt/beta-catenin
K-756 is a direct and selective inhibitor of tankyrase (TNKS), which inhibits the ADP-ribosylation activity of TNKS1 and TNKS2 (IC50s: 31 and 36 nM, respectively).
T6842 G007-LK PARP , Wnt/beta-catenin
G007-LK is a selective inhibitor of TNKS1 and TNKS2, with IC50s of 46 nM and 25 nM, respectively.
T3168 MN-64 MN64 Others , PARP , Wnt/beta-catenin
MN-64 is a tankyrases inhibitor, showed 6 nM potency against tankyrase 1, isoenzyme selectivity, and Wnt signaling inhibition.
T6197 PJ34 PARP
PJ34 HCl is the hydrochloride salt of PJ34, which is a PARP inhibitor with EC50 of 20 nM and is equally potent to PARP1/2.
T2484 AZD-2461 PARP
AZD2461 is a novel PARP inhibitor.
T6578 ME0328 PARP
ME0328 is a potent and selective PARP inhibitor with IC50 of 0.89 μM for PARP3, about 7-fold selectivity over PARP1.
T6181 UPF 1069 PARP
UPF 1069 is a specific PARP2 inhibitor ( IC50: 0.3 μM). It is ~27-fold selective against PARP1.
T6768 AZ6102 PARP , Wnt/beta-catenin
AZ6102 is a potent TNKS1/2 inhibitor that has 100-fold selectivity against other PARP family enzymes and shows IC50 of 5 nM for Wnt pathway inhibition in DLD-1 cells.
T21524 4-amino-1,8-Naphthalimide PARP
4-amino-1,8-Naphthalimide (4-ANI) is a PARP inhibitor with IC50 of 180 nM
T22264 AZ9482 PARP
AZ9482 is a selective and potent inhibitor of PARP featuring an amide linkage to a 2-piperazinyl-3-cyano-pyridine. AZ9482 exhibits very potent activity of centrosome declustering with EC50 of < 18 nM in HeLa cells.
T7042 1,5-Isoquinolinediol PARP
1, 5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1; IC50: 0.39 μM). The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis. 1, 5-Isoquinolinediol...
T6253 Talazoparib LT-673,BMN-673 PARP
Talazoparib (LT-673) is a new-type PARP inhibitor (IC50: 0.58 nM), It similarly binds to PARP1/2 (Kis: 1.2/0.85 nM).
T50098 TIQ-A PARP
TIQ-A is a PARP1 inhibitor which involved in DNA single-strand break repair via the base excision repair pathway. PARP1 is triggered by DNA damage and its excessive activation has been proposed as a causative factor in m...
T3062 WIKI4 PARP , Wnt/beta-catenin
WIKI4 is a potent inhibitor of Wnt/β-catenin signaling and tankyrase 2 (TNKS2).
T5058 Pamiparib BGB-290 PARP
Pamiparib (BGB-290) is an orally active, potent, highly selective PARP inhibitor(IC50 of 0.9 nM and 0.5 nM for PARP1 and PARP2, respectively). It has potent PARP trapping, and capability to penetrate the brain, and can b...
T6339 AG14361 AG 14361,AG-14361 PARP
AG14361 is an effective inhibitor of PARP1 (Ki<5 nM).
T9165 AZD5305 PARP
AZD5305 is a potent, selective and oral active PARP inhibitor.
T4472 NMS-P118 PARP
NMS-P118 is a potent, selective and orally available Inhibitor of PARP-1 for cancer therapy.
T4471 E7449 Stenoparib,UNII-9X5A2QIA7C Others , PARP
E7449 (UNII-9X5A2QIA7C) is a potent PARP1 and PARP2 inhibitor and also inhibits TNKS1 and TNKS2, with IC50s of 2.0, 1.0, ~50 and ~50 nM for PARP1, PARP2, TNKS1 and TNKS2, respectively, using 32P-NAD+ as substrate.
T22414 RBN012759 PARP
RBN012759, a potent and selective PARP14 inhibitor, decreases pro-tumor macrophage function and elicits inflammatory responses in tumor explants.
T9593 Senaparib IMP4297 PARP
Senaparib (IMP4297) is a novel highly potent and selective oral PARP1/2 inhibitor with strong antitumor activity.
T22749 DR2313 DR 2313 PARP
DR2313 is a competitive inhibitor of poly(ADP-ribose) polymerase (IC50: 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). It also has neuroprotective.
T3649 BGP-15 BGP15,BGP-15 2HCl PARP
BGP-15 (BGP-15 2HCl) is a PARP inhibitor with protecting effect after ischemia-reperfusion injury.
T12695 RBN-2397 PARP
RBN-2397 is a potent, selective and orally active accross species NAD+ competitive PARP7 inhibitor with IC50 less than 3 nM.
T7896 BYK204165 RT-017290 PARP
BYK204165 (RT-017290) is a potent PARP inhibitor (PARP1; IC50 = 44.67 nM for human recombinant PARP1 in an enzyme assay)
T9497 Niraparib tosylate monohyrate PARP
Niraparib, also know as MK-4827, is an inhibitor of poly (ADP-ribose) polymerase (PARP) with potential antineoplastic activity. MK4827 inhibits PARP activity, enhancing the accumulation of DNA strand breaks and promoting...
T5399 GeA-69 PARP
GeA-69 (GeA69) is a selective and allosteric PARP14 macrodomain 2 (MD2) inhibitor (Kd: 0.86 μM in ITC assays).
T8478 SC-43 Apoptosis , Phosphatase , STAT
SC-43 is a potent and orally active agonist of SHP-1 (PTPN6). SC-43 inhibits the phosphorylation of STAT3 and induces cell apoptosis, and with anti-fibrotic and anticancer effects.
T9430 Venadaparib NOV140101,IDX-1197 PARP
Venadaparib (NOV140101) (IDX-1197) is a potent, selective and orally active PARP inhibitor with IC50s of 1.4 nM and 1.0 nM for PARP1 and PARP2, respectively. Venadaparib is insensitive to PARP-5. Venadaparib prevents the...
T2124 PJ34 hydrochloride PJ34 HCl PARP
PJ34 hydrochloride (PJ34 HCl) is a potent specific inhibitor of PARPl/2.

Compounds

PARP/PI3K-IN-1
T12365
Synonym:
Target: PARP, PI3K
PARP-1-IN-4
T78182
Synonym:
Target: Others, PARP
PARP-1-IN-2
T62281
Synonym:
Target: PARP
PARP-1-IN-3
T78157
Synonym:
Target: Apoptosis, PARP
PARP/EZH2-IN-1
T40310
Synonym: PARP/EZH2-IN-1
Target:
PARP-2-IN-3
T73027
Synonym:
Target: Apoptosis, PARP
3-Aminobenzamide
T6329
Synonym: 3-AB,INO1001,INO-1001,3-ABA,PARP-IN-1,INO 1001
Target: PARP
PARP-2-IN-1
T12364
Synonym:
Target: Others
PARP-2/1-IN-2
T72862
Synonym:
Target:
PARP-1-IN-13
T79330
Synonym:
Target: PARP
PARP-1-IN-1
T61798
Synonym:
Target:
PARP-1/2-IN-1
T62508
Synonym:
Target:
PARP-1/HDAC-IN-1
T61962
Synonym:
Target:
VEGFR/PARP-IN-1
T79647
Synonym:
Target: PARP
PROTAC PARP/EGFR ligand 1
T74173
Synonym:
Target:
PARP-1/2-IN-2
T78787
Synonym:
Target: PARP
PARP1-IN-5 dihydrochloride 
T9610
Synonym:
Target: PARP
RK-287107
T16761
Synonym:
Target: Others, PARP
G244-LM
T8964
Synonym:
Target: Others, PARP
JW 55
T1807
Synonym: JW55
Target: PARP, Wnt/beta-catenin
K-756
T15639
Synonym:
Target: PARP, Wnt/beta-catenin
G007-LK
T6842
Synonym:
Target: PARP, Wnt/beta-catenin
MN-64
T3168
Synonym: MN64
Target: Others, PARP, Wnt/beta-catenin
PJ34
T6197
Synonym:
Target: PARP
AZD-2461
T2484
Synonym:
Target: PARP
ME0328
T6578
Synonym:
Target: PARP
UPF 1069
T6181
Synonym:
Target: PARP
AZ6102
T6768
Synonym:
Target: PARP, Wnt/beta-catenin
4-amino-1,8-Naphthalimide
T21524
Synonym:
Target: PARP
AZ9482
T22264
Synonym:
Target: PARP
1,5-Isoquinolinediol
T7042
Synonym:
Target: PARP
Talazoparib
T6253
Synonym: LT-673,BMN-673
Target: PARP
TIQ-A
T50098
Synonym:
Target: PARP
WIKI4
T3062
Synonym:
Target: PARP, Wnt/beta-catenin
Pamiparib
T5058
Synonym: BGB-290
Target: PARP
AG14361
T6339
Synonym: AG 14361,AG-14361
Target: PARP
AZD5305
T9165
Synonym:
Target: PARP
NMS-P118
T4472
Synonym:
Target: PARP
E7449
T4471
Synonym: Stenoparib,UNII-9X5A2QIA7C
Target: Others, PARP
RBN012759
T22414
Synonym:
Target: PARP
Senaparib
T9593
Synonym: IMP4297
Target: PARP
DR2313
T22749
Synonym: DR 2313
Target: PARP
BGP-15
T3649
Synonym: BGP15,BGP-15 2HCl
Target: PARP
RBN-2397
T12695
Synonym:
Target: PARP
BYK204165
T7896
Synonym: RT-017290
Target: PARP
Niraparib tosylate monohyrate
T9497
Synonym:
Target: PARP
GeA-69
T5399
Synonym:
Target: PARP
SC-43
T8478
Synonym:
Target: Apoptosis, Phosphatase, STAT
Venadaparib
T9430
Synonym: NOV140101,IDX-1197
Target: PARP
PJ34 hydrochloride
T2124
Synonym: PJ34 HCl
Target: PARP
1 2 3 4
Cat No. Product Name Synonyms Targets
T8184 Fucosterol PARP , Endogenous Metabolite , PPAR
Fucosterol is isolated from E. stolonifera with anti-diabetic, anti-adipogenic and anti-cancer activities. It regulates adipogenesis via modulation of PPARα and C/EBPα expression.
T7982 3,6-Dihydroxyflavone Others
3,6-Dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway.
T13795 Nicotinamide riboside Sirtuin
Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities.
T8150 Nudifloramide 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide PARP , Endogenous Metabolite
Nudifloramide (1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide) is one of the end degradation products of nicotinamide-adenine dinucleotide (NAD).
T7443 4'-Methoxychalcone PARP , PPAR
4'-Methoxychalcone with a variety of pharmacological activities, such as anti-tumor and anti-inflammatory activities.
T5S2358 Dehydrocorydaline Dehydrocorydalin,13-Methylpalmatine BCL , PARP , p38 MAPK , Caspase , Parasite , Autophagy
1. Dehydrocorydaline (13-Methylpalmatine) exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSC-LC cells. 2. Dehydrocorydaline stimulates p38 MAPK activation, which can enhance heterodimeriz...
T6780 Benzamide Amid kyseliny benzoove,Phenylcarboxyamide,Benzoylamide PARP , Endogenous Metabolite
Benzamide (Amid kyseliny benzoove), an inhibitor of poly(ADP-ribose) polymerase, is a derivative of benzoic acid.
T10990 Dehydrocorydaline chloride 13-Methylpalmatine chloride BCL , PARP , p38 MAPK , Caspase , Parasite , Autophagy
Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid with anti-inflammatory and anti-cancer activity. Can improve the activation of p38 MAPK.
T2S2362 Dehydrocorydaline nitrate BCL , Others , PARP , p38 MAPK , Caspase , Parasite , Autophagy
1. Dehydrocorydaline(DHC) not only inhibits antibody-mediated allergic reactions but also influences cell-mediated allergic reactions, and the inhibitory effect of Corydalis Tuber on allergic reactions may be partially a...
T6220 Nicotinamide riboside chloride Sirtuin , Endogenous Metabolite
Nicotinamide riboside chloride, also known as NR and SRT647, is a pyridine-nucleoside form of vitamin B3 that functions as a precursor to nicotinamide adenine dinucleotide or NAD+.
TN2883 3',4'-Dimethoxyflavone Others , PARP
3',4'-Dimethoxyflavone is a standard compound of flavonoids with numerous medicinal activities.
T5S1805 5,7-Dihydroxychromone 5,7-Dihydroxy-4H-Chromen-4-One Others , Virus Protease , PARP , Caspase , Nrf2
1. 5,7-Dihydroxychromone (5,7-Dihydroxy-4H-Chromen-4-One) isolated from DME is one of the active compounds that may contribute to regulate blood glucose levels. 2. 5,7-Dihydroxychromone exerts neuroprotective effect agai...
T1152 Albendazole SKF-62979 HIF/HIF Prolyl-Hydroxylase , Microtubule Associated , Antibiotic , Parasite
Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations.
T8296 5,​7,​4'-​Trimethoxyflavone 4',5,7-Trimethoxyflavone Apoptosis , PARP , Caspase
5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.
T2851 Daphnetin 7,8-Dihydroxycoumarin,Daphnetol EGFR , PKA , PKC , Parasite , Autophagy
Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM), and PKC (IC50: 25.01 μM), also exhibit anti-oxidant and anti-...
T4085 Paris saponin VII Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII Apoptosis , BCL , Others , PARP , p38 MAPK , Akt , Caspase , P-gp , Autophagy
Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.
T3S1471 Cucurbitacin IIA Dihydrocucurbitacin Q1,Hemslecin A,Curcurbitacin IIA Apoptosis , Survivin
1. Cucurbitacin IIA (Dihydrocucurbitacin Q1) can induce apoptosis and enhance autophagy , contributes to the anti-inflammatory activity of Cucurbitacin IIA against inflammation-related diseases. 2. Cucurbitacin IIA is a ...
TN1880 Lucidenic acid B Lucidenicacid B Apoptosis , Caspase
Lucidenic acid B (Lucidenicacid B), a natural compound extracted from Ganoderma lucidum, induces activation of caspase-9 and caspase-3 and cleavage of PARP, which can induce apoptosis in human leukemia cells through mito...
T9113 Myristicin Myristicine IL Receptor , Anti-infection , BCL , P450 , PARP , 5-HT Receptor , Caspase , GABA Receptor , NO Synthase
Myristicin (Myristicine) is a natural product found in spices and umbelliferous plants. Myristicin has anti-cholinergic, Antibacterial, and hepatoprotective effects, it also has anti-inflammatory properties related with ...
T6S2391 L-Chicoric Acid (-)-Chicoric acid,trans-Caffeoyltartaric acid,Chicoric acid,dicaffeoyltartaric acid Others , HIV Protease
L-Chicoric Acid (trans-Caffeoyltartaric acid) has been shown to inhibit hyaluronidase and HIV-1 integrase, and to possess phagoeytosis stimulatory activity in vitro and in vivo and antiviral acitivy. L-Chicoric acid may ...
T4973 Paraxanthine 1,7-DIMETHYLXANTHINE Endogenous Metabolite
Paraxanthine (1,7-dimethylxanthine) is a metabolite of caffeine (sc-202514) which functions as an adenosine receptor ligand and a PARP-1 inhibitor in pulmonary epithelial cells. Studies suggest that Paraxanthine is struc...
T6942 Picolinamide 2-Pyridinecarboxamide,2-Carbamoylpyridine,2-Picolinamide,Picolinoylamide PARP
Picolinamide (Picolinoylamide) is found to be a strong inhibitor of poly (ADP-ribose) synthetase of nuclei from rat pancreatic islet cells.
T24638 Picrasidine M
Picrasidine M is a PARP-1 inhibitor.
TN1139 Dehydrocavidine Dehydrocorydaline BCL , PARP
Dehydrocavidine (Dehydrocorydaline) has antitumor activity, it inhibits MCF-7 cell proliferation by inducing apoptosis mediated by regulating Bax/Bcl-2, activating caspases as well as cleaving PARP.
T73403 Aviculin
Aviculin, a lignan glycoside, exhibits significant anticancer properties, particularly in inhibiting the metabolic activity of MCF-7 cells to below 50%, with an IC 50 value of 75.47 μM. It promotes apoptosis in breast ca...
TN4046 Excisanin A MMP , FAK , PARP , GSK-3 , NF-κB , Wnt/beta-catenin , Akt , Caspase , PI3K , Prostaglandin Receptor , JNK
ExcisaninA may be a potent inhibitor of AKT signaling pathway in tumor cells, it can inhibit invasion by suppressing MMP-2 and MMP-9 expression, it may be a potential anti-metastatic chemotherapeutic agent for the treatm...

Natural Products

Fucosterol
T8184
Synonym:
Target: PARP, Endogenous Metabolite, PPAR
3,6-Dihydroxyflavone
T7982
Synonym:
Target: Others
Nicotinamide riboside
T13795
Synonym:
Target: Sirtuin
Nudifloramide
T8150
Synonym: 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide
Target: PARP, Endogenous Metabolite
4'-Methoxychalcone
T7443
Synonym:
Target: PARP, PPAR
Dehydrocorydaline
T5S2358
Synonym: Dehydrocorydalin,13-Methylpalmatine
Target: BCL, PARP, p38 MAPK, Caspase, Parasite, Autophagy
Benzamide
T6780
Synonym: Amid kyseliny benzoove,Phenylcarboxyamide,Benzoylamide
Target: PARP, Endogenous Metabolite
Dehydrocorydaline chloride
T10990
Synonym: 13-Methylpalmatine chloride
Target: BCL, PARP, p38 MAPK, Caspase, Parasite, Autophagy
Dehydrocorydaline nitrate
T2S2362
Synonym:
Target: BCL, Others, PARP, p38 MAPK, Caspase, Parasite, Autophagy
Nicotinamide riboside chloride
T6220
Synonym:
Target: Sirtuin, Endogenous Metabolite
3',4'-Dimethoxyflavone
TN2883
Synonym:
Target: Others, PARP
5,7-Dihydroxychromone
T5S1805
Synonym: 5,7-Dihydroxy-4H-Chromen-4-One
Target: Others, Virus Protease, PARP, Caspase, Nrf2
Albendazole
T1152
Synonym: SKF-62979
Target: HIF/HIF Prolyl-Hydroxylase, Microtubule Associated, Antibiotic, Parasite
5,​7,​4'-​Trimethoxyflavone
T8296
Synonym: 4',5,7-Trimethoxyflavone
Target: Apoptosis, PARP, Caspase
Daphnetin
T2851
Synonym: 7,8-Dihydroxycoumarin,Daphnetol
Target: EGFR, PKA, PKC, Parasite, Autophagy
Paris saponin VII
T4085
Synonym: Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII
Target: Apoptosis, BCL, Others, PARP, p38 MAPK, Akt, Caspase, P-gp, Autophagy
Cucurbitacin IIA
T3S1471
Synonym: Dihydrocucurbitacin Q1,Hemslecin A,Curcurbitacin IIA
Target: Apoptosis, Survivin
Lucidenic acid B
TN1880
Synonym: Lucidenicacid B
Target: Apoptosis, Caspase
Myristicin
T9113
Synonym: Myristicine
Target: IL Receptor, Anti-infection, BCL, P450, PARP, 5-HT Receptor, Caspase, GABA Receptor, NO Synthase
L-Chicoric Acid
T6S2391
Synonym: (-)-Chicoric acid,trans-Caffeoyltartaric acid,Chicoric acid,dicaffeoyltartaric acid
Target: Others, HIV Protease
Paraxanthine
T4973
Synonym: 1,7-DIMETHYLXANTHINE
Target: Endogenous Metabolite
Picolinamide
T6942
Synonym: 2-Pyridinecarboxamide,2-Carbamoylpyridine,2-Picolinamide,Picolinoylamide
Target: PARP
Picrasidine M
T24638
Synonym:
Target:
Dehydrocavidine
TN1139
Synonym: Dehydrocorydaline
Target: BCL, PARP
Aviculin
T73403
Synonym:
Target:
Excisanin A
TN4046
Synonym:
Target: MMP, FAK, PARP, GSK-3, NF-κB, Wnt/beta-catenin, Akt, Caspase, PI3K, Prostaglandin Receptor, JNK

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-01188 PARP Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
PARP Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 114.5 kDa and the accession number is A0A024R3T8.
TMPY-02465 PARP Protein, Mouse, Recombinant (His) Mouse Baculovirus Insect Cells
PARP Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 115 kDa and the accession number is Q921K2.
TMPY-02421 PARP3 Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
Poly(ADP-ribose) polymerase 3 (PARP3) is an important member of the PARP family and shares high structural similarities with both PARP1 and PARP2. Poly(ADP-ribose) polymerase 3 (PARP3), a critical player in cellular resp...
TMPH-01944 PARP9 Protein, Human, Recombinant (His & Myc) Human HEK293 Cells
PARP9 Protein, Human, Recombinant (His & Myc) is expressed in HEK293.
TMPH-01945 TIPARP Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
TIPARP Protein, Human, Recombinant (His) is expressed in Baculovirus.
TMPH-01879 PARP11 Protein, Human, Recombinant (His) Human E. coli
Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins. Plays a role in nuclear envelope stability and nuclear remodeling during spermiogenesis. PARP11 Protein, Human, Recombinant (His) is exp...
TMPH-01881 PARP2 Protein, Human, Recombinant (GST & His) Human Baculovirus Insect Cells
PARP2 Protein, Human, Recombinant (GST & His) is expressed in Baculovirus insect cells with N-GST and C-6xHis tag. The predicted molecular weight is 92.8 kDa and the accession number is Q9UGN5.
TMPH-01942 PARP14 Protein, Human, Recombinant (His & Myc) Human HEK293 Cells
PARP14 Protein, Human, Recombinant (His & Myc) is expressed in HEK293.
TMPH-01943 PARP4 Protein, Human, Recombinant (His) Human E. coli
PARP4 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-01880 PARP2 Protein, Human, Recombinant (His) Human E. coli
PARP2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 72.2 kDa and the accession number is Q9UGN5.
TMPH-01882 PARP9 Protein, Human, Recombinant (His) Human E. coli
PARP9 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 30.0 kDa and the accession number is Q8IXQ6.
TMPH-01941 PARP12 Protein, Human, Recombinant (His & Myc) Human E. coli
PARP12 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPY-02831 Caspase-7 Protein, Human, Recombinant (His) Human E. coli
Caspase 7, also known as caspase-7 and MCH3, belongs to the cysteine-aspartic acid protease (caspase) family. Caspases play a role in the signal transduction pathways of apoptosis, necrosis and inflammation. There are tw...
Cat No. Product Name
L3400 Clinical Compound Library

3404 compounds
A unique collection of 3404 compounds in clinical trial phases for high throughput screening (HTS) and high content screening (HCS);
L2191 Anti-Breast Cancer Compound Library

1939 compounds
A unique collection of 1939 compounds with anti-breast cancer therapeutic activity or targeting breast cancer’s major signaling pathways, can be used for anti-breast cancer drug discovery and mechanism study;
TargetMol