Search Result

Search Results for " parp "

Targets

Libraries

Clinical Compound Library Anti-Breast Cancer Compound Library

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Compounds

Cat No.	Product Name
T62281	PARP-1-IN-2		PARP
	PARP-1-IN-2 is a potent PARP1 inhibitor that crosses the blood-brain barrier (IC50: 149 nM).PARP-1-IN-2 showed significa...		PARP
T40310	PARP/EZH2-IN-1
	PARP/EZH2-IN-1 is a novel compound that functions as a dual inhibitor for both PARP (IC50 6.87 nM) and EZH2 (IC50 36.51 ...
T12365	PARP/PI3K-IN-1		PI3K
	PARP/PI3K-IN-1 is a potent inhibitor of PARP/PI3K(pIC50 values of 8.22).		PI3K
T12364	PARP-2-IN-1		Others
	PARP-2-IN-1 is a potent and selective inhibitor of PARP-2(IC50 of 11.5 nM).		Others
T61798	PARP-1-IN-1
	PARP-1-IN-1 is a highly selective and orally active inhibitor of the enzyme PARP-1, with an IC50 value of 0.96 nM. It ex...
T72862	PARP-2/1-IN-2
	PARP-2/1-IN-2 , the enantiomer of Veliparib , is a potent PARP inhibitor with K i s of 2 and 5 nM against PARP-2 and PAR...
T62508	PARP-1/2-IN-1
	PARP-1-/2-IN-1 is a potent inhibitor of PARP-1 (IC50: 0.51 nM) and PARP-2 (IC50: 23.11 nM).
T61962	PARP-1/HDAC-IN-1
	PARP-1/HDAC-IN-1 is an effective dual inhibitor of PARP-1/HDAC6, with IC50 of 68.90 nM and 510 nM respectively. PARP-1/H...
T74173	PROTAC PARP/EGFR ligand 1
	PROTAC PARP/EGFR ligand 1 is an active compound that can be used for the synthesis of dual PARP EGFR degraders by proteo...
T6329	3-Aminobenzamide	3-AB,INO 1001,3-ABA,INO1001,INO-1001,PARP-IN-1	PARP
	INO-1001 is an effective inhibitor of PARP (IC50<50 nM in CHO cells) and a mediator of oxidant-induced myocyte dysfuncti...		PARP
T9610	PARP1-IN-5 dihydrochloride		PARP
	PARP1-IN-5 dihydrochloride is an orally active, potent and selective PARP-1 inhibitor (IC50 =14.7 nM). PARP1-IN-5 dihydr...		PARP
T6197	PJ34		PARP
	PJ34 HCl is the hydrochloride salt of PJ34, which is a PARP inhibitor with EC50 of 20 nM and is equally potent to PARP1/...		PARP
T2484	AZD-2461		PARP
	AZD2461 is a novel PARP inhibitor.		PARP
T6181	UPF 1069		PARP
	UPF 1069 is a specific PARP2 inhibitor ( IC50: 0.3 μM). It is ~27-fold selective against PARP1.		PARP
T6578	ME0328		PARP
	ME0328 is a potent and selective PARP inhibitor with IC50 of 0.89 μM for PARP3, about 7-fold selectivity over PARP1.		PARP
T1807	JW 55	JW55	Wnt/beta-catenin , PARP
	JW 55 is an effective and selective β-catenin signaling pathway inhibitor, works by inhibition of the PARP domain of tan...		Wnt/beta-catenin , PARP
T6768	AZ6102		PARP , Wnt/beta-catenin
	AZ6102 is a potent TNKS1/2 inhibitor that has 100-fold selectivity against other PARP family enzymes and shows IC50 of 5...		PARP , Wnt/beta-catenin
T6339	AG14361	AG-14361,AG 14361	PARP
	AG14361 is an effective inhibitor of PARP1 (Ki<5 nM).		PARP
T3168	MN-64	MN64	Wnt/beta-catenin , Others , PARP
	MN-64 is a tankyrases inhibitor, showed 6 nM potency against tankyrase 1, isoenzyme selectivity, and Wnt signaling inhib...		Wnt/beta-catenin , Others , PARP
T16761	RK-287107		PARP , Others
	RK-287107 is an effective and specific inhibitor of tankyrase (IC50s: 14.3 and 10.6 nM for tankyrase-1 and tankyrase-2, ...		PARP , Others