iop — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T0142	Brinzolamide	AL-4862	Carbonic Anhydrase
	Brinzolamide (AL-4862) is a Carbonic Anhydrase Inhibitor. The mechanism of action of brinzolamide is as a Carbonic Anhydrase Inhibitor.		Carbonic Anhydrase
T1522	Iopromide	Iopromidum,Ultravist	Others
	Iopromide (Iopromidum) is a low osmolar, non-ionic contrast agent for intravascular use.		Others
T0352	Dibenzothiophene	Imino semicarbazide,Diphenylene sulfide	Others
	Dibenzothiophene (Imino semicarbazide), a component of petroleum oils, is a sulfur-containing polycyclic aromatic hydrocarbon (PAH) derivate consisting of 3 fused rings with keratolytic activity.		Others
T20371	2'-Hydroxypropiophenone	AI3 11684,AI311684,AI3-11684	Others
	2'-Hydroxypropiophenone (AI3-11684) is an agent that is derivatized salicylaldoxime.		Others
T5701	OPHIOPOGONIN D		RAAS , Calcium Channel , NF-κB , PPAR
	Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.		RAAS , Calcium Channel , NF-κB , PPAR
T4104	Ophiopojaponin C	Ophiopogonin C	Others
	Ophiopogonin C' pharmacological activities may be related to the substances in nucleus mainly.		Others
T50088	N-phenylthiophene-2-carboximidamide		Others
	N-phenylthiophene-2-carboximidamide is a thiophene derivative that functions as an inhibitor of protein tyrosine kinases (PTKs) and a ligand for G protein-coupled receptors (GPCRs).		Others
T50019	1-[(5-chlorothiophen-2-yl)sulfonyl]pyrrolidine-2-carboxylic acid		Others
	1-[(5-chlorothiophen-2-yl)sulfonyl]pyrrolidine-2-carboxylic acid has been used as a starting material for the synthesis of drugs, polymers, etc., and has also been used to synthesize bioactive compounds such as peptides,...		Others
T3809	Liriope muscari baily saponins C		Others
	Liriope muscari baily saponins C has an anti-thrombotic activity due to down-regulation of the increased mRNA expression levels of TF and IL-6.		Others
T8603	ETHYL 2-AMINO-4-METHYL-5-PHENYLTHIOPHENE-3-CARBOXYLATE		Prostaglandin Receptor
	ETHYL 2-AMINO-4-METHYL-5-PHENYLTHIOPHENE-3-CARBOXYLATE targets the prostaglandin E2 receptor EP2 subtype (human)		Prostaglandin Receptor
T4244	Methylophiopogonone A		Others
	Methylophiopogonone A, an isoflavone isolated from the roots of Ophiopogon japonicus, exhibits anti-inflammatory properties.		Others
T5S1262	Methylophiopogonanone A		Others
	1. Methylophiopogonanone A has anti-inflammatory and anti-oxidative properties. 2. Methylophiopogonanone A has therapeutic potential against cerebral I/R injury through its ability to attenuate BBB disruption by regulati...		Others
T16470	Penthiopyrad	Vertisan,MTF-753	Antifungal
	Penthiopyrad (MTF-753) shows a broad spectrum of antifungal activity and suppresses fungal respiration. Penthiopyrad can be used in studies about foliar and soil-borne plant diseases.		Antifungal
T4S1439	6'-O-beta-D-Glucosylgentiopicroside	6'-O-Glucosylgentiopicroside	Antifungal
	1. 6'-O-beta-D-Glucosylgentiopicroside (6'-O-Glucosylgentiopicroside) may have antifungal activity.		Antifungal
T2770	Gentiopicroside	Gentiopicrin	P450 , HCV Protease
	Gentiopicroside (Gentiopicrin), a naturally occurring iridoid glycoside, extracted from Gentiana manshurica Kitag, inhibits P450 activity, with an IC50 and a Ki of 61 μM and 22.8 μM for CYP2A6; has antianti-inflammatorya...		P450 , HCV Protease
T19160	7,8-Dihydro-L-biopterin		Endogenous Metabolite
	7,8-Dihydro-L-biopterin is a kind of oxidation product of tetrahydrobiopterin.		Endogenous Metabolite
T3821	Deapioplatycodin D	Deapi-platycodin D,DesapioplatycodinD	Others , HCV Protease
	Deapioplatycodin D and platycodin D can regulate the production and secretion of airway mucin and, at least in part, explains the traditional use of aqueous extract of APG as expectorants in diverse inflammatory pulmonar...		Others , HCV Protease
T41247	Thioperamide maleate	MR-12842 maleate	Histamine Receptor
	Thioperamide maleate (MR-12842 maleate) is an effective and selective antagonist of H3 receptor (Ki = 4.3 nM) for inhibition of [3H]histamine synthesis (Ki = 31 nM).		Histamine Receptor
T1630	Tiopronin	Thiopronine,Acadione,Captimer	ROS
	Tiopronin (Acadione), a sulfhydryl acylated derivative of glycine, leads to a reduction in urinary cystine concentration and subsequently reduces cystine stone formation.		ROS
T1342	3-Chloropropiophenone		Others
	3-Chloropropiophenone (CPP) is a synthetic compound that is used in the synthesis of organic reagents, pharmaceuticals, and other products. It has the ability to inhibit certain enzymes (e.g. cytochrome P450) and inhibit...		Others