T68078 |
Gantofiban
|
183547-57-1
|
98%
|
|
Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.
|
TQ0291 |
Firategrast
|
402567-16-2
|
98%
|
|
Firategrast is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervous system (CNS)...
|
T13473 |
αvβ1 integrin-IN-1
|
1689540-62-2
|
98%
|
|
αvβ1 integrin-IN-1 is a potent and selective inhibitor of αvβ1 integrin (IC50 of 0.63 nM) with antifibrotic effects.
|
T41151L |
K34c hydrochloride
|
|
98%
|
|
K34c hydrochloride is an alpha5β1 integrin antagonist for glioblastoma study.
|
T13473L |
αvβ1 integrin-IN-1 TFA (1689540-62-2 free base)
|
T13473L
|
98%
|
|
αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM).
|
T8726 |
Cyclo(RGDyK)
|
217099-14-4
|
98%
|
|
Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.
|
TP2148 |
LXW7 TFA (1313004-77-1 free base)
|
TP2148
|
98%
|
|
LXW7 TFA, a cyclic peptide containing Arg-Gly-Asp (RGD), is an integrin αvβ3 inhibitor with an anti-inflammatory effect. LXW7 has a high binding affinity to αvβ3...
|
T14558 |
BI-1950
|
1159724-42-1
|
98%
|
|
BI-1950 is a highly potent lymphocyte function associated antigen-1 (LFA-1) inhibitor and the LFA-1 is an essential component in normal immune system function an...
|
T9914 |
Vedolizumab
|
943609-66-3
|
98%
|
|
Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of Crohn's disease and ulcerative colitis.
|
T13478 |
β-glycosidase-IN-1
|
176485-27-1
|
98%
|
|
β-glycosidase-IN-1 is a piperidine derivative, and is an inhibitor of β-glycosidase. It has hypoglycemic activity.
|
T29089 |
Valategrast hydrochloride
|
828271-96-1
|
98%
|
|
Valategrast hydrochloride, a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.
|
T16100 |
Balamapimod
|
863029-99-6
|
98%
|
|
Balamapimod is a reversible inhibitor of Ras/Raf/MEK. It also has a potential anti-tumor activity.
|
T6806 |
Cilengitide TFA
|
199807-35-7
|
98%
|
|
Cilengitide is a potent integrin inhibitor for αvβ3 receptor and αvβ5 receptor with IC50 of 4.1 nM and 79 nM in cell-free assays, respectively; ~10-fold selectiv...
|
T14573 |
Bimosiamose disodium
|
187269-60-9
|
98%
|
|
Bimosiamose disodium has anti-inflammatory effects[1]. Bimosiamose disodium (TBC-1269Z) is a nonoligosaccharide pan-selectin inhibitor with IC50s of 88 μM, 20 μM...
|
T6657 |
SB273005
|
205678-31-5
|
98%
|
|
SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.
|
T14574 |
Bimosiamose
|
187269-40-5
|
98%
|
|
Bimosiamose has anti-inflammatory effects[1]. Bimosiamose (TBC-1269) is a nonoligosaccharide pan-selectin antagonist with IC50s of 88 μM, 20 μM, and 86 μM for E-...
|
T3881 |
Vaccarin
|
53452-16-7
|
98%
|
|
Vaccarin is a major flavonoid glycoside in Vaccariae semen, its biotransformation pathways involves methylation, hydroxylation, glycosylation and deglycosylation...
|
T8523 |
ILK-IN-3
|
6975-75-3
|
98%
|
|
ILK-IN-3 is an inhibitor of integrin linked kinase, and with antitumor activity.
|
T6182 |
Tirofiban
|
144494-65-5
|
98%
|
|
Tirofiban (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.
|
TN1244 |
3'-Demethylnobiletin
|
112448-39-2
|
98%
|
|
3'-Demethylnobiletin has chemopreventive effects on colon carcinogenesis, it can significantly inhibit the growth of human colon cancer cells, cause cell-cycle a...
|