enhancing — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T6682	STF-118804	STF 118804,STF118804	Apoptosis , NAMPT
	STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM.		Apoptosis , NAMPT
T4335	GNE-617	GNE617	NAMPT
	GNE-617, a specific NAMPT inhibitor(IC50=5 nM), shows potency in xenograft models of cancer.		NAMPT
T12171	Nampt-IN-5		P450 , NAMPT
	Nampt-IN-5 is a potent and orally active inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) .		P450 , NAMPT
T4376	Nampt-IN-1	LSN3154567	c-Fms , NAMPT , CSF-1R
	Nampt-IN-1 (LSN3154567) (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with an IC50 of 3.1 nM.		c-Fms , NAMPT , CSF-1R
T2718	Palmatine chloride		Others , Indoleamine 2,3-Dioxygenase (IDO) , Aurora Kinase
	Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.		Others , Indoleamine 2,3-Dioxygenase (IDO) , Aurora Kinase
T15758	Linopirdine	DuP 996	Potassium Channel , TRP/TRPV Channel
	Linopirdine (DuP 996) is a TRPV1 agonist. Linopirdine is an orally active and selective M-type K+ current (IM; Kv7; KCNQ Channels) inhibitor (IC50: 2.4 μM). Linopirdine is a cognitive enhancer. It acts by stimulating rel...		Potassium Channel , TRP/TRPV Channel
T2230	Paeoniflorin	Peoniflorin	HSP , COX
	Paeoniflorin (Peoniflorin) is a herbal constituent extracted from the root of Paeonia albiflora Pall.		HSP , COX
T5S0802	Palmatine	Berbericinine,Burasaine	Indoleamine 2,3-Dioxygenase (IDO) , AChR , AChE , Aurora Kinase
	1. Palmatine (Burasaine) is an inhibitor of dopamine generation. 2. Palmatine could potentially be developed for the treatment of flavivirus infections. 3. Palmatine has been used in the treatment of jaundice, dysentery,...
T1998	CHS-828	CHS 828,GMX1778	Apoptosis , NAMPT
	CHS-828 (GMX1778), a pyridyl cyanoguanidine, is an effective inhibitor of NAD+ biosynthesis enzyme NAMPT (IC50 <25 nM).		Apoptosis , NAMPT
T12854	SBI-797812		NAMPT
	SBI-797812 is structurally similar to active-site directed inhibitor of NAMPT(NAMPT with EC50 of 0.37 μM).		NAMPT
T3026	(-)-Huperzine A	HupA,Huperzine A	Apoptosis , AChR , AChE , iGluR
	(-)-Huperzine A (HupA) , an active Lycopodium alkaloid extracted from the traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the tr...		Apoptosis , AChR , AChE , iGluR
T2644	(E)-Daporinad	Daporinad,(E)-N-[4-(1-BENZOYL-PIPERIDIN-4-YL)-BUTYL]-3-PYRIDIN-3-YL-ACRYLAMIDE,APO866,FK866	NAMPT , Transferase , Autophagy
	(E)-Daporinad (FK866) is a small molecule inhibitor of nicotinamide phosphoribosyltransferase (NMPRTase), with potential antineoplastic and antiangiogenic activities.		NAMPT , Transferase , Autophagy
T19211	BM152054		Others
	BM152054 is a potent PPARγ ligand that induces glucose utilization in peripheral tissues by enhancing insulin action.		Others
T7829	FK962		Somatostatin
	FK962 is an somatostatin release enhancer , exerts cognitive-enhancing actions.		Somatostatin
T21715	BRD6688		HDAC
	BRD6688 is a selective HDAC2 inhibitor that acts by enhancing the learning and memory processes		HDAC
T8725	A 582941 HCl (848591-90-2(free base))		AChR
	A-582941 is a alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties		AChR
T2S0122	D-(-)-Mandelic acid	Mandelic acid,(R)-(-)-Mandelic acid,D-(−)-Mandelic Acid,R-(−)-Mandelic Acid	Others
	D-(-)-Mandelic acid ((R)-(-)-Mandelic acid) has the health function of killing sperm, reducing Yin, inhibiting bacteria, anti-inflammation and enhancing vagina self-cleaning.		Others
T3S1589	Notoginsenoside Fa		Others
	1. Notoginsenosides Fa and R4 show significant neurite outgrowth enhancing activities in human neuroblastoma SK-N-SH cells.		Others
T2S0342	Armillarisin A		Others , Interleukin
	Armillarisin A enhancing the role of macrophages, inhibiting bacteria growth, improving the protein metabolism, and regulating liver function.		Others , Interleukin
T9106	E1231		Sirtuin
	E1231 is an activator of SIRT1 . E1231 protects from experimental atherosclerosis and lowers plasma cholesterol and triglycerides by enhancing ABCA1 expression.		Sirtuin