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Cat No. | Product Name | Synonyms | Targets |
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T7202 | ITE | AhR , Aryl Hydrocarbon Receptor | |
ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR) (Ki : 3 nM), has immunosuppressive activity. | |||
T1960 | YL-109 | AhR , Aryl Hydrocarbon Receptor | |
YL-109, a novel anticancer agent, can inhibit breast Y cell growth and invasiveness in vitro and in vivo. | |||
T21966 | MeBIO | GSK-3 , Aryl Hydrocarbon Receptor , CDK | |
MeBIO is an agonist of aryl hydrocarbon receptor, with IC50 of 44 and 55 μM for GSK-3 and CDK1/CyclinB, respectively. MeBIO does not affect GSK-3β. | |||
T4608 | PDM2 | AhR , Aryl Hydrocarbon Receptor | |
PDM 2 is a potent and selective aryl hydrocarbon receptor (AhR) antagonist. | |||
T15410 | GNF351 | Aryl Hydrocarbon Receptor | |
GNF351 is a full antagonist of the aryl hydrocarbon receptor (AHR)with the capacity to inhibit both DRE-dependent and -independent activity. GNF351 is minimal toxicity in mouse or human keratinocytes. GNF351 competes wit... | |||
T2448 | CH-223191 | CH 223191 | AhR , Aryl Hydrocarbon Receptor |
CH-223191 is a potent and specific antagonist for aryl hydrocarbon receptor (AhR). | |||
T5622 | BAY-218 | AHR antagonist 1 | AhR , Aryl Hydrocarbon Receptor |
BAY-218 (AHR antagonist 1) is an aryl hydrocarbon receptor (AHR) antagonist , has an IC50 of 39.9 nM in human cell line. | |||
T20625 | Prochloraz | Sporgon,Prelude | Estrogen Receptor/ERR , AhR , Androgen Receptor , Antifungal |
Prochloraz (Prelude) is a broad-spectrum contact imidazole fungicide. Prochloraz inhibits human placental microsomal aromatase in vitro (IC50 = 40 nM). Prochloraz also acts as an estrogen receptor (IC50s = 25 μM) and and... | |||
T4607 | CAY 10465 | CAY10465,CAY10465 Exclusive | AhR , Aryl Hydrocarbon Receptor |
CAY 10465 is a selective and high-affinity AhR agonist, with a Ki of 0.2 nM, and shows no effect on estrogen receptor (Ki >100000 nM). | |||
T10270 | BAY 2416964 | Aryl Hydrocarbon Receptor | |
BAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist(example 192, IC50: 341 nM). It has the potential for cancer treatment. | |||
T10007 | 1,4-Chrysenequinone | Chrysene-1,4-dione | AhR |
1,4-Chrysenequinone (Chrysene-1,4-dione) is an activator of aryl hydrocarbon receptor (AhR). | |||
T3389 | Antitumor agent-21 | TRX818 | Others |
Antitumor agent-21 (TRX818) is an orally bioavailable agent with potential antineoplastic and anti-vasculogenic mimicry (VM) activities. | |||
TQ0257 | FICZ | 6-Formylindolo[3,2-b]carbazole | Aryl Hydrocarbon Receptor |
FICZ (6-Formylindolo[3,2-b]carbazole) is a potent aryl agonist for the hydrocarbon receptor (AhR, Kd: 70 pM). | |||
T1831 | StemRegenin 1 | SR1 | AhR , Aryl Hydrocarbon Receptor |
StemRegenin 1 (SR1) is an aryl hydrocarbon receptor (AhR) inhibitor. | |||
T21704 | 5-fluoro 203 | 5F-203,NSC-703786 | Others |
5-fluoro 203 (NSC-703786) is a cytotoxic molecule leading to cell death by forming DNA adducts. 5-fluoro 203 induces aryl hydrocarbon receptor signaling, and elevates expression of CYP1A1. 5-fluoro 203 treatment of cells... | |||
T13276 | VAF347 | Aryl Hydrocarbon Receptor | |
VAF347 is a cell-permeable and highly affinity agonist of the aryl hydrocarbon receptor (AhR) with anti-inflammatory effects. | |||
T2623 | PD98059 | PD 98059 | ERK , Aryl Hydrocarbon Receptor , MEK , Autophagy |
PD98059 is an MEK inhibitor that inhibits MEK1 and MEK2 (IC50=2/50 μM) and is non-ATP-competitive. PD98059 is also antagonistic as a ligand for AHR. PD98059 inhibits autophagy. | |||
T2148 | Carbidopa monohydrate | Carbidopa Hydrate,S(-)-Carbidopa | Decarboxylase , Aryl Hydrocarbon Receptor |
Carbidopa monohydrate (S(-)-Carbidopa) is an inhibitor of DOPA decarboxylase, preventing the conversion of levodopa to dopamine. | |||
T4644 | Tapinarof | GSK2894512,Benvitimod,WBI 1001 | AhR , Aryl Hydrocarbon Receptor |
Tapinarof (Benvitimod) is targeted as a topical cream treatment for psoriasis, a chronic autoimmune skin disease. | |||
T0640 | Benzyl butyl phthalate | BBP,1,2-benzenedicarboxylic acid,butyl phenylmethyl ester,Butyl benzyl phthalate | Others , Aryl Hydrocarbon Receptor |
Benzyl butyl phthalate (1,2-benzenedicarboxylic acid) is used as a plasticizer for PVC. | |||
T2707 | Pifithrin-α hydrobromide | Pifithrin hydrobromide,Pifithrin-α (PFTα) HBr,Pifithrin-α,PFTα,PFTα hydrobromide | Ferroptosis , Aryl Hydrocarbon Receptor , p53 |
Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-responsive genes. | |||
T13012 | Stearyldiethanolamine | PEG-2 Stearamine,2,2'-(Octadecylazanediyl)diethanol,2,2'-(Octadecylimino)diethanol | Others |
Stearyldiethanolamine (2,2'-(Octadecylazanediyl)diethanol) can be used in studies about antibacterial nonwoven fabric and antibacterial freshness-keeping film. | |||
T0790 | Carbaryl | 1-naphthyl methylcarbamate,Sevin | AChR |
Carbaryl (1-naphthyl methylcarbamate) is a carbamate insecticide and parasiticide. It is a potent anticholinesterase agent belonging to the carbamate group of reversible cholinesterase inhibitors. It has a particularly l... | |||
T34713 | Stearyl tyrosine | Stearyl-tyrosine,Stearyltyrosine | |
Stearyl tyrosine is an immunoadjuvants, long-chain stearyl ester of amino acids and peptides. | |||
T73752 | Glutarylcarnitine lithium | ||
Glutarylcarnitine lithium, a key diagnostic metabolite for malonic aciduria and glutaric aciduria type I, is routinely monitored in the majority of newborn screening programs utilizing tandem mass spectrometry [1]. | |||
T76448 | Arylomycin A2 | ||
Arylomycin A2, a lipopeptide antibiotic, functions as a type I signal peptidase (SPase I) inhibitor. It exhibits antibacterial properties [1]. | |||
T76163 | Arylsulfatase | ||
Arylsulfatase, a type I sulfatase enzyme found in both prokaryotes and eukaryotes, is frequently utilized in biochemical research [1]. | |||
T22036 | Arylquin 1 | ||
Arylquin 1, a prostate-apoptosis-response-4 (Par-4) secretagogue, specifically targets vimentin to facilitate Par-4 secretion. Additionally, it promotes non-apoptotic cell death in cancer cells by inducing lysosomal memb... | |||
T19912 | Distearyl thiodipropionate | NSC65493,NSC-65493,NSC 65493 | |
Distearyl thiodipropionate is an agent of biochemical. | |||
T34712 | Stearyl caprate | Octadecyl decanoate | |
Stearyl caprate is a biochemicla. | |||
T34957 | Tristearyl citrate | ||
Tristearyl citrate is a bioactive chemical. | |||
T65655 | Stearyl gallate | ||
Stearyl gallate is a useful organic compound for research related to life sciences. The catalog number is T65655 and the CAS number is 10361-12-3. | |||
T22268 | Benzyldimethylstearylammonium chloride | Benzyldimethylstearylammonium Chloride Hydrate | Others |
Benzyl dimethyl stearyl ammonium chloride hydrate is a kind of mild smell chemical | |||
T82293 | Glutaryl coenzyme A lithium | ||
Glutaryl coenzyme A lithium, a derivative of the endogenous metabolite glutaryl coenzyme A, is utilized in experiments related to HMG-CoA or glutaryl-CoA. | |||
T34714 | Stearylbetaine | NSC 36343,NSC-36343,NSC-9859,NSC 9859,NSC36343 | |
Stearylbetaine is a bioactive chemical. | |||
T13662 | Diarylalkane derivative 1 | Others | |
Diarylalkane derivative 1 is used for the research of pancreatitis. | |||
T31948 | Glutarylleucine | Glutaryl-L-leucine | |
Glutarylleucine is a bioactive chemical. | |||
T10106 | 3-arylisoquinolinamine derivative | Others | |
3-arylisoquinolinamine derivative is a compound with antitumor activity. | |||
T31481 | Diisostearyl adipate | ||
Diisostearyl adipate can be used for skin care. | |||
T9658 | DCZ3301 | NPS ALX Compound 4a hydrochloride(1:1)(299433-10-6 Free base) | Others |
DCZ3301 is a novel aryl-guanidino inhibitor. | |||
T9704 | 1-Ethynylpyrene | P450 | |
1-Ethynylpyrene is an aryl acetylenic inhibitor of CYTP450 1A1(IC50=0.18 μM), 1A2(IC50 = 0.32 μM), and 2B1(IC50 = 0.04 μM). | |||
T12071 | MKC9989 | IRE1 | |
MKC9989 is an inhibitor of Hydroxy aryl aldehydes (HAA). MKC9989 also inhibits IRE1α with an IC50 of 0.23 to 44 μM. | |||
T8980 | SGA360 | Aryl Hydrocarbon Receptor | |
SGA360 is a selective aryl hydrocarbon (Ah) receptor modulator. It exhibits anti-inflammatory properties. | |||
T19446 | N-Boc-O-tosyl hydroxylamine | Others | |
N-Boc-O-tosyl hydroxylamine is nitrogen source for the N-amination of aryl and alkyl amines. | |||
T10269 | AHR antagonist 2 | Aryl Hydrocarbon Receptor | |
AHR antagonist 2 is an antagonist of the aryl hydrocarbon receptor. The IC50s for human AHR and mouse AHR are 0.885 and 2.03 nM, respectively. | |||
T0609 | Azobenzene | Diazene,Diphenyldiazene | Others |
Azobenzene (Diazene) is a compound constituted of two phenyl rings linked by an N=N double bond. Azobenzene is the simplest example of an aryl azo chemical compound. The term 'azobenzene' or simply 'azo' is constantly us... | |||
T5541 | PDM11 | 1-[2-(4-Chloro-phenyl)-vinyl]-3,5-diMeth,PDM 11 | AhR |
PDM11 (1-[2-(4-Chloro-phenyl)-vinyl]-3,5-diMeth) is an antagonist of aryl hydrocarbon receptor (AhR) | |||
T10325 | ANI-7 | Chk | |
ANI-7 is an activator of aryl hydrocarbon receptor (AhR) pathway. ANI-7 inhibits the growth of multiple cancer cells and potently and selectively inhibits the growth of MCF-7 breast cancer cells (GI50: 0.56 μM). | |||
T10526 | β-NF-JQ1 | Others | |
β-NF-JQ1 is a PROTAC that recruits aryl hydrocarbon receptor E3 (AhR E3) ligase to target proteins. β-NF-JQ1 uses β-NF as an AhR ligand to target bromodomain (BRD)-containing proteins and induce AhR and BRD protein inter... | |||
T3637 | Pifithrin-β hydrobromide | Cyclic PFT-α,PFT-β,Cyclic Pifithrin-α hydrobromide,Pifithrin-β,PFT β (hydrobromide) | Ferroptosis , p53 |
Pifithrin-β hydrobromide (Cyclic PFT-α) is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of stroke and neurodegenerative disorder... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN1451 | Brevifolincarboxylic acid | AhR , Aryl Hydrocarbon Receptor , Glucosidase | |
Brevifolincarboxylic acid is a natural product isolated from Polygonum capitatum, it has inhibitory effect on the aryl hydrocarbon receptor (AhR). Brevifolincarboxylic acid is an α-glucosidase inhibitor with an IC50 of 3... | |||
T6795 | Carbidopa | (S)-(-)-Carbidopa,Lodosyn | Decarboxylase , Aryl Hydrocarbon Receptor |
Carbidopa (Lodosyn) is an aromatic-L-amino-acid decarboxylase inhibitor (IC50: 29±2 μM). It is used in PARKINSON DISEASE to reduce peripheral adverse effects of LEVODOPA. | |||
T5786 | TETRAHYDROPIPERINE | Cosmoperine | P450 , TRP/TRPV Channel |
Tetrahydropiperine (Cosmoperine) is a natural product derived from piperine, can be used to treat convulsion, epilepsy, relieve pain, and control insects. | |||
T4928 | L-Kynurenine | (S)-Kynurenine | AhR , Aryl Hydrocarbon Receptor , Endogenous Metabolite |
L-Kynurenine ((S)-Kynurenine) is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase, KMO, and KAT associated with the suppression of antitumor immune responses. It has ... | |||
T0878 | Diosmin | Venosmine,Diosmil,Barosmin | Aryl Hydrocarbon Receptor , Norepinephrine |
Diosmin (Venosmine) is a bioflavonoid that strengthens vascular walls. | |||
TN2883 | 3',4'-Dimethoxyflavone | Others , PARP | |
3',4'-Dimethoxyflavone is a standard compound of flavonoids with numerous medicinal activities. | |||
T5281 | Skatole | Scatole,3-Methylindole,3-Methylindole,3-Methyl-1H-indole,beta-Methylindole | AhR , p38 MAPK , Aryl Hydrocarbon Receptor , Endogenous Metabolite , Antibacterial , Autophagy , Antifungal |
Skatole (3-Methyl-1H-indole) is produced by intestinal bacteria. Skatole regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38. | |||
T4939 | Indole-3-pyruvic acid | 3-(3-Indolyl)-2-oxopropanoic acid | Others |
Indole-3-pyruvic acid (3-(3-Indolyl)-2-oxopropanoic acid) is a compound involved in the biosynthesis of Indole-3-acetic acid, a plant hormone which plays important roles in regulating growth and responses to environmenta... | |||
T2947 | Indole-3-carbinol | I3C,3-Indolemethanol,Indole-3-Methanol | E1/E2/E3 Enzyme , NF-κB , Aryl Hydrocarbon Receptor , Endogenous Metabolite , p53 |
Indole-3-carbinol (I3C), a naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, inhibits NF-κB and IκBα kinase activation. | |||
T19340 | Glutarylcarnitine | O-glutaroyl-L-carnitine | Endogenous Metabolite |
Glutarylcarnitine (O-glutaroyl-L-carnitine) is a diagnostic metabolite for malonic aciduria and glutaric aciduria type I monitored in most tandem mass spectrometry newborn screening programmes. | |||
T5802 | Stearyl glycyrrhetinate | Antiviral , Antibacterial | |
Stearyl glycyrrhetinate, the stearyl ester of 18-β-glycyrrhetinic acid, has been demonstrated to improve antiviral effects, reduce inflammation and suppress allergies in the pharmaceutical and cosmetic industry. | |||
T83542 | (E)-p-Coumaryl alcohol | (E)-p-Hydroxycinnamyl alcohol | |
(E)-p-Coumaryl alcohol, a coumarin metabolite, exhibits notable cytotoxicity and can be isolated from Alpinia officinarum and Rhodiola rosea. It is utilized in inflammation research [1]. | |||
TN2028 | P-Coumaryl alcohol | Others | |
p-Coumaryl alcohol derivatives have antioxidant activity. | |||
T81506 | Petunidin-3-O-(6-O-p-coumaryl)-5-O-diglucoside | ||
Petunidin-3-O-(6-O-p-coumaryl)-5-O-diglucoside, a natural compound, can be extracted from grapes [1]. | |||
TN3842 | Diarylcomosol III | Others | |
Diarylcomosol III shows inhibitory effects on melanogenesis in B16 melanoma cells, it is a promising therapeutic agent for the treatment of skin disorders. | |||
TN4433 | Licoarylcoumarin | cAMP , HIV Protease , Antifection | |
Licoarylcoumarin is a strong inhibitor of adenosine 3',5'-cyclic monophosphate (cAMP) phosphodiesterase. Licoarylcoumarin has antibacterial effects on the VRE strains; it has anti-HIV activity, and it has inhibitory effe... | |||
TN6363 | Tsaokoarylone | ||
Tsaokoarylone is a natural product for research related to life sciences. The catalog number is TN6363 and the CAS number is 811471-20-2. | |||
T83321 | 4-Demethyldeoxypodophyllotoxin | Chk | |
4-Demethyldeoxypodophyllotoxin, an aryl tetrahydronaphthalenyl lignan analog from the roots of Podophyllum peltatum, has anticancer activity and modulates the Chk-2 signaling pathway in MCF-7 breast cancer cells. | |||
T3776 | Rhapontigenin | Protigenin | P450 , Antibacterial , Antifungal |
Rhapontigenin (Protigenin) is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50: 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens. R... | |||
TN6694 | 5,6-Benzoflavone | β-Naphthoflavone,beta-NF | Antioxidant |
5,6-Benzoflavone (β-Naphthoflavone) is an exogenous ligand for the aryl hydrocarbon receptor, which disrupts zinc homeostasis in human hepatocellular carcinoma HepG2 cells. 5,6-Benzoflavone (β-Naphthoflavone) possesses a... | |||
T4938 | Potassium 1H-indol-3-yl sulfate | Indoxyl sulfate potassium salt,Potassium 3-indoxyl sulfate | AhR , Endogenous Metabolite |
Potassium 1H-indol-3-yl sulfate (Potassium 3-indoxyl sulfate) is an agonist for the human Aryl Hydrocarbon Receptor (AhR). The Aryl Hydrocarbon Receptor (AhR) has recently emerged as a pathophysiological regulator of imm... | |||
TN6366 | Lupinalbin A | ||
Lupinalbin A as the most potent estrogen receptor α- and aryl hydrocarbon receptor agonist in Eriosema laurentii de Wild. (Leguminosae). It exerts anti-inflammatory effects via the inhibition of pro-inflammatory cytokine... | |||
T75433 | Norisoboldine hydrochloride | ||
Norisoboldine hydrochloride, an orally active aryl hydrocarbon receptor (AhR) agonist and a prominent isoquinoline alkaloid found in Radix Linderae, is utilized for research purposes in the study of Rheumatoid Arthritis ... | |||
T73402 | Flavipin | ||
Flavipin, an aryl hydrocarbon receptor (Ahr) agonist, activates Ahr downstream gene expression in mouse CD4+ T cells and CD11b+ macrophages. This compound disrupts the stabilizing effect of Arid5a on the newly identified... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00958 | AHR Protein, Human, Recombinant (His) | Human | E. coli |
AHR Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPJ-00586 | SULT1A2 Protein, Human, Recombinant (His) | Human | E. coli |
Sulfotransferase 1A2 (SULT1A2) is a member of the Sulfotransferase 1 family. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. SULT1A2 is a cy... | |||
TMPH-00957 | ARNT Protein, Human, Recombinant (His) | Human | Yeast |
ARNT Protein, Human, Recombinant (His) is expressed in Yeast. | |||
TMPY-05911 | Influenza B (B/Maryland/1959) Hemagglutinin/HA Protein (His) | Influenza B | HEK293 |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPY-02654 | FDPS Protein, Human, Recombinant (His) | Human | E. coli |
Z-farnesyl diphosphate synthase (FDPS) is an enzyme belonging to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. Z-farnesyl diphosphate synthase (FDPS) functions... | |||
TMPY-00451 | FDPS Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Z-farnesyl diphosphate synthase (FDPS) is an enzyme belonging to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. Z-farnesyl diphosphate synthase (FDPS) functions... | |||
TMPY-01709 | HIF-1 alpha Protein, Human, Recombinant (His) | Human | E. coli |
HIF-1 alpha, also known as HIF1A, contains 1 basic helix-loop-helix (bHLH) domain, 1 PAC (PAS-associated C-terminal) domain, and 2 PAS (PER-ARNT-SIM) domains. It is one of the two subunits of Hypoxia-inducible factor-1 (... |
Cat No. | Product Name | ||
---|---|---|---|
L7810 | High Solubility Polyfunctional Group Fragment Library | 1159 compounds | |
Highly soluble multifunctional fragment library contains 1159 kinds of fragment molecules. |