ubiquitin proteasome

E3 ligase Ligand 23 is a cereblon binding agent that degrades Ikaros or Aiolos via the ubiquitin proteasome.

Bis-PEG23-endo-BCN, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Amino-PEG9-alcohol is a PEG-based linker for PROTACs [Proteolysis Targeting Chimeras], facilitating the conjugation of two essential ligands for PROTAC formation and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Fmoc-PEG12-NHS ester, a PEG-based linker for PROTACs, facilitates the joining of two essential ligands, crucial for the formation of PROTAC molecules, and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

ARV-393 is a PROTAC degrader targeting BCL6 with the advantage of being highly potent and orally available.ARV-393 recruits BCL6 and E3 ligase cerebellum to rapidly degrade BCL6 through the cell's natural ubiquitin proteasome system for the treatment of diffuse large b-cell lymphoma (DLBCL) and non-Hodgkin's lymphoma (NHL).

SNIPER(TACC3)-1 targets TACC3 protein degradation via the ubiquitin-proteasome pathway.It induces cancer cell death.

SNIPER(TACC3)-2 targets TACC3 protein degradation via the ubiquitin-proteasome pathway. It induces cancer cell death.

2-(Benzyloxy)ethanol is a PEG-based linker for PROTACs, facilitating the connection of two essential ligands necessary for forming PROTAC molecules, thereby enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Acid-C2-PEG3-NHS ester is a PEG-based linker for PROTACs, joining two essential ligands crucial for PROTAC formation, enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Acid-PEG1-C2-Boc is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Acid-PEG2-C2-Boc is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Acid-PEG3-PFP ester is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Acid-PEG5-C2-Boc, a PEG-based linker for PROTACs, facilitates the connection of two essential ligands necessary for PROTAC molecule formation, enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Acid-PEG5-TEMPO is a PEG-based linker for PROTACs, joining two essential ligands crucial for PROTAC molecule formation, and facilitates selective protein degradation using the ubiquitin-proteasome system within cells.

Acid-PEG6-C2-Boc is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Acid-PEG9-NHS ester is a PEG-based linker for PROTACs [proteolysis-targeting chimeras], facilitating the conjugation of two essential ligands, essential for PROTAC molecule formation, and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Ald-C2-PEG4-azide is a PEG-based linker for PROTACs that joins two essential ligands, enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Ald-CH2-PEG4-Boc is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Ald-Ph-PEG2-NH-Boc is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Ald-Ph-PEG4-Boc is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules, and enabling selective protein degradation by leveraging the [ubiquitin-proteasome] system within cells.

Ald-Ph-PEG4-NH-Boc, a PEG-based linker for PROTACs, connects two essential ligands, crucial for forming PROTAC molecules. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Ald-Ph-PEG6-acid is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Ald-Ph-PEG6-Boc is a PEG-based linker for PROTACs that joins two essential ligands, crucial for the formation of PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Alkyne-ethyl-PEG1-Boc is a PEG-based linker for PROTACs that connects two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.