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TargetMol is dedicated to ensuring our products remain at the forefront of scientific research. Every month, we update over 200 new compounds, covering various fields and targeting a diverse range of molecular targets. Our catalog is continually expanding to provide you with the latest and most pertinent compounds for your research needs.
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Anti-Mouse PD-1 Antibody (RMP1-14)
T78269
RMP1-14 is an IgG1-like immunoglobulin and anti-Mouse PD-1 antibody that blocks PD-1/PD-L1 signaling.
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IACS-52825
T793032640376-72-1In house
IACS-52825 is a selective and potent dual leucine zipper kinase (DLK) inhibitor that reverses para-mechanical aberrant pain in a CIPN mouse model for the study of neurological disorders.
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Brigimadlin
T699232095116-40-6
Brigimadlin (BI 907828) is an orally active and highly potent E3 ubiquitin-protein ligase
MDM2-p53 antagonist with antitumor activity.Brigimadlin can be used to study metastatic BTC, PDAC, lung adenocarcinoma, or bladder cancer.
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Eribulin
T13688253128-41-5
Eribulin (B1939) is a nonpaclitaxel microtubule kinetic inhibitor with anticancer activity that inhibits polymerization of microtubule protein subunits by preventing lengthening and shortening of microtubules during cell division.Eribulin is used in the study of metastatic breast cancer and solid tumors.
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RMC-6291
T751312641998-63-0
RMC-6291 is an orally available, highly potent KRASG12C(ON) inhibitor with anticancer and antitumor activity that acts through spatial blockade of RAS effector binding.RMC-6291 blocks ERK signaling and induces apoptosis in KRASG12C-mutant H358 cells.
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Gimsilumab
T770251648796-29-5
Gimsilumab (MORAb-022) is a humanized monoclonal antibody targeting granulocyte macrophage colony-stimulating factor for the study of COVID-19-induced inflammation and hypoxemia.
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SB 216641 hydrochloride
T23315193611-67-5
SB 216641 hydrochloride (SB-216641A) is a selective 5-HT1B/D receptor antagonist with anxiolytic properties that antagonizes the vasoconstrictor response mediated by sumatriptan. 10-O-Methylprotosapphosporin is an HbF inducer that can be used in the study of metabolic disorders and diabetes.
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HOIPIN-8 sodium
T628262519537-70-1
HOIPIN-8 sodium is a potent linear ubiquitin chain assembly complex (LUBAC) inhibitor for the study of inflammatory and immune diseases.
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diABZI STING agonist-1 trihydrochloride
Cited
T55162138299-34-8
diABZI STING agonist-1 (trihydrochloride) is stimulator of interferon genes (STING) receptor agonist.
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CitedPF-610355
T16509862541-45-5In house
PF-610355 is a long-acting and potent β2-adrenergic receptor agonist (EC50: 0.26 nM).PF-610355 can be used to study asthma and COPD.
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Azelaprag
T143902049980-18-7In house
Azelaprag (AMG 986) is an effective small-molecule apelin receptor agonist. Azelaprag can be used to treat neurological diseases and cardiovascular diseases.
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2',3'-cGAMP sodium
T10065L2734858-36-5
2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium) is a second messenger in cellular innate immunity and is catalyzed by cGAMP synthase (cGAS) under DNA binding conditions. 2',3'-cGAMP sodium binds to STING to form a dimer, inducing the production and expression of interferon-β and other cytokines.
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AS-136A
T62160949898-66-2
AS-136A is an orally active measles virus RNA-dependent RNA polymerase (RdRp) inhibitor with antiviral activity that inhibits measles virus and blocks viral RNA synthesis.
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