influenza

Influenza HA 126-138 acetate is a influenza virus hemagglutinin (HA) peptide acetate comprising amino acids 126-138. Influenza HA 126-138 acetate induces thymic and peripheral T-cell apoptosis.

Influenza Matrix Protein (61-72) is a peptide derived from the matrix protein of influenza viruses, encompassing amino acids 61-72, and has the ability to elicit a CD4+ T-cell response.

Influenza HA (110-119) refers to a specific fragment (110-119) derived from the hemagglutinin protein of the influenza virus. This fragment has the ability to induce the proliferation of Treg cells.

NS2 (114-121), Influenza, is a fragment derived from the nonstructural protein 2 (NS2) of the influenza virus, serving as an epitope for influenza research and useful for studying CD8+ cytotoxic T lymphocyte (CTL) responses in antiviral immunity.

Influenza A virus-IN-1, a dihydropyrrolidones derivative, is a highly effective inhibitor of various subtypes of influenza A virus (IAV) with IC 50 values ranging from 3.11 μM to 7.13 μM. It effectively suppresses IAV replication and enhances the expression of key antiviral cytokines, such as IFN-β, and the antiviral protein MxA.

Influenza virus-IN-6 (Compound 35) is a potent inhibitor of the N-terminal domain of the polymerase acidic protein (PA N) endonuclease subunit of the influenza virus, with an inhibitory concentration 50 (IC 50) value of 0.20 μM [1].

Anti-Influenza agent 5 (Compound IIB-2), a chalcone-like derivative, serves as an influenza nuclear export inhibitor, effectively inhibiting oseltamivir-resistant strains and hindering viral proliferation by obstructing the export of influenza virus nucleoprotein [1].

Influenza HA (518-526) is an immunodominant epitope in H2d mice post flu virus infection.

CEF8, Influenza Virus NP (383-391), is an influenza A virus nucleoprotein containing residues 383 to 391, and it is the most important HLA-B*2705-restricted epitope in the nucleoprotein of influenza A viruses, associated with escape from cytotoxic T lymphocytes-mediated immunity. [HLA-B*3501 restricted influenza virus nucleoprotein epitope (383-391).]

HLA-B*08 restricted influenza virus nucleoprotein epitope.

This peptide is a H2-Db-restricted epitope from Influenza nucleoprotein (147-155).

This peptide is an H2-Db-restricted epitope from the Influenza A/PR/8/34 nucleoprotein.

This peptide is a H-2Kd-restricted epitope from Influenza nucleoprotein (147-155).

CEF1, Influenza Matrix Protein M1 (58-66), is an epitope derived from the matrix protein of the influenza A virus. GILGFVFTL is an HLA-A2-restricted epitope from this matrix M1 protein.

Influenza HA (126-138) is a peptide derived from the hemagglutinin (HA) protein of the influenza virus, consisting of amino acids 126-138, and has the ability to induce apoptosis in both thymic and peripheral T-cells.

Influenza HA (307-319) acetate is the 307-319 amino acid fragment of the influenza virus hemagglutinin (HA) protein, an HLA-DRB1 0101-restricted epitope polypeptide with the sequence PKYVKQNTLKLAT, which can be used for the study of influenza virus immunogenicity as well as for the development of vaccines and diagnostic reagents against influenza virus.

Anti-Influenza agent 4 is a potent and selective inhibitor of the influenza virus, effectively inhibiting the A/Parma and A/Roma strains with EC50s of 62 nM and 150 nM, respectively.

Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity.

Baloxavir (S-033447) is a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit.

(-)-Arctigenin ((-)-Arctigenin) is found in burdock. (-)-Arctigenin is isolated from Cnicus benedictus, Forsythia viridissima, Arctium lappa, Ipomoea cairica and others (CCD). Arctigenin is a lignan found in certain plants of the Asteraceae, including the Greater burdock (Arctium lappa) and Saussurea heteromalla. It has shown antiviral and anticancer effects. It is the aglycone of arctiin.

2'-Deoxy-2'-fluorouridine serves as an intermediate in the synthesis of antiviral agents targeting influenza viruses[1].

Triazavirin, a nucleoside analogue of nucleic acid, is an antiviral agent.

RN-18 antagonizes Vif function and inhibits HIV-1 replication only in the presence of A3G. RN-18 increases cellular A3G levels in a Vif-dependent manner and increases A3G incorporation into virions without inhibiting general proteasome-mediated protein degradation. RN-18 enhances Vif degradation only in the presence of A3G, reduces viral infectivity by increasing A3G incorporation into virions and enhances cytidine deamination of the viral genome.

CU-T12-9 is a potent TLR1/2 agonist(EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay). It acts by activating the NFkB pathway, upregulating proinflammatory cytokines, and enhancing TLR1 and TLR2 dimerization.CU-T12-9 activates both the innate and the adaptive immune systems. CU-T12-9 selectively activates the TLR1/2 heterodimer, not TLR2/6. CU-T12-9 signals through NF-κB and invokes an elevation of the downstream effectors TNF-α, IL-10, and iNOS.